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A STUDY ON DEVELOPMENT OF LARGE-SCALE MEDICAL ONTOLOGY FOR CLINICAL USE

Research Project

Project/Area Number 16200039
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical systems
Research InstitutionThe University of Tokyo

Principal Investigator

OHE Kazuhiko  The University of Tokyo, THE UNIVERSITY OF TOKYO HOSPITAL, PROFESSOR (40221121)

Co-Investigator(Kenkyū-buntansha) ONOGI Yuzo  INTERNATIONAL UNIVERSITY OF HEALTH AND WELFARE, MITA HOSPITAL, Assoc. PROFESSOR (90233593)
HATANO Kenji  THE UNIVERSITY OF TOKYO, Graduate School of Medicine, RESEARCH Assoc (60311619)
MIYOK Kengo  THE UNIVERSITY OF TOKYO HOSPITAL, 医学部附属病院, LECTURER (40302690)
SHINOHARA Nobuo  THE UNIVERSITY OF TOKYO HOSPITAL, 医学部附属病院, RESEARCH Assoc (90345223)
YAMAGUCHI Izumi  THE UNIVERSITY OF TOKYO HOSPITAL, 医学部附属病院, RESEARCH Assoc (80345222)
Project Period (FY) 2004 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥46,540,000 (Direct Cost: ¥35,800,000、Indirect Cost: ¥10,740,000)
Fiscal Year 2007: ¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
Fiscal Year 2006: ¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000)
Fiscal Year 2005: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000)
Fiscal Year 2004: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
KeywordsONTOLOOGY / THESAURUS / NATURAL LANGUAGE PROCESSING / ELECTRONIC MEDICAL RECORD / HEALTH INFORMATION SYSTEMS / MEDICAL TERMINOLOGY / KNOWLEDGE-BASED SYSTEMS / 医療用語
Research Abstract

For the purpose of developing large-scale medical ontology for clinical use, we conducted the following four subjects in the research period.
1) Automatic extraction and classification of relationship among clinical terminology from medical dictionary
2) Automatic extraction of relationship among human body elements
3) Automatic extraction of important clinical findings from diagnostic reports
4) Consideration about database structure for large-scale medical ontology
After the above work, we developed a top-level ontology framework, using ontology editor "HOZO", in the domain of internal medicine, surgery, clinical findings, surgical procedure, and anatomy. For example, general disease concept was classified into formal disease that can be represented by the etiology of the disease, syndrome that can be represented only by the list of clinical findings and symptoms. For anatomical structures, entity for representing an anatomical elements was introduced and the spatial relationship between the entity and the adjacent structures was represented. All the anatomical entities could be represented by this method. We verified that three thousand diseases could be represented by this top-level ontology framework.

Report

(5 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • Research Products

    (46 results)

All 2008 2007 2006 2005 2004 Other

All Journal Article (27 results) (of which Peer Reviewed: 13 results) Presentation (18 results) Remarks (1 results)

  • [Journal Article] 情報検索尺度Okapi-BM25と交換可能語ペアを用いた自動ICDコーディングに関する研究2007

    • Author(s)
      荒牧英治, 今井健, 梶野正幸, 美代賢吾, 大江和彦
    • Journal Title

      医療情報学 27(1)

      Pages: 101-107

    • NAID

      10022604900

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 情報検索尺度Okapi-BM25と交換可能語ペアを用いた自動ICDコーディングに関する研究2007

    • Author(s)
      荒牧 英治, 今井 健, 梶野 正幸, 美代 賢吾, 大江 和彦
    • Journal Title

      医療情報学 27(1)

      Pages: 101-107

    • NAID

      10022604900

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 情報検索手法による長い病名の自動ICDコーディングに関する研究2006

    • Author(s)
      荒牧英治, 今井健, 梶野正幸, 美代賢吾, 大江和彦
    • Journal Title

      医療情報学 26(Suppl. )

      Pages: 852-855

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] メタ関係を利用したテキストからの人体部位関係の抽出2006

    • Author(s)
      荒牧英治, 今井健, 梶野正幸, 美代賢吾, 大江和彦
    • Journal Title

      言語処理学会第12回年次大会

      Pages: 508-511

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary 2006 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 医学用語属性と構文情報を用いた診断報告書からの重要所見情報の抽出2006

    • Author(s)
      今井健, 荒牧英治, 梶野正幸, 美代賢吾, 小野木雄三, 大江和彦
    • Journal Title

      言語処理学会第12回年次大会

      Pages: 89-92

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 構文情報と医学用語属性を用いた画像診断所見オントロジ-の構築の試み2006

    • Author(s)
      今井健, 荒牧英治, 梶野正幸, 美代賢吾, 大江和彦
    • Journal Title

      医療情報学 25・6

      Pages: 395-403

    • NAID

      10022604184

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 情報検索手法による長い病名の自動ICDコ-ディングに関する研究2006

    • Author(s)
      荒牧英治, 今井健, 梶野正幸, 美代賢吾, 大江和彦
    • Journal Title

      第26回医療情報学連合大会論文集

      Pages: 512-515

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 医学用語属性と構文情報を用いた診断報告書からの重要所見情報の抽出2006

    • Author(s)
      荒牧英治, 今井健, 梶野正幸, 美代賢吾, 小野木雄三, 大江和彦
    • Journal Title

      言語処理学会第12回年次大会

      Pages: 89-92

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Toward Medical Ontology via Natural Language Processing2005

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Masayo Kashiwagi, Masayuki Kajino, Kengo Miyo, Kazuhiko Ohe
    • Journal Title

      International Joint Conference on Natural Language Processing (IJCNLP)workshop OntoLex2005

      Pages: 53-58

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 臨床医学オントロジーとターミノロジー2005

    • Author(s)
      大江和彦
    • Journal Title

      医療情報学 25(Suppl)

      Pages: 131-132

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary 2005 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 診断報告書における病理医から臨床医へのリクエスト表現の分析2005

    • Author(s)
      光石豊, 遠藤徹, 河添悦昌, 高田真美, 田中勝弥, 美代賢吾, 大江和彦
    • Journal Title

      医療情報学 25(suppl)

      Pages: 688-691

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 自然言語処理による臨床医学オントロジーの自動構築の試み2005

    • Author(s)
      荒牧英治, 今井健, 柏木聖代, 梶野正幸, 美代賢吾, 大江和彦
    • Journal Title

      医療情報学 25(Suppl)

      Pages: 966-969

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary 2005 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 自然言語処理を用いた画像診断所見オントロジー構築の試み2005

    • Author(s)
      今井健, 荒牧英治, 柏木聖代, 梶野正幸, 美代賢吾, 大江和彦
    • Journal Title

      医療情報学 25(Suppl)

      Pages: 972-975

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary 2005 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 構文情報と医学用語属性を用いた画像診断所見オントロジーの構築の試み2005

    • Author(s)
      今井健, 荒牧英治, 梶野正幸, 美代賢吾, 大江和彦
    • Journal Title

      医療情報学 25・6

      Pages: 395-403

    • NAID

      10022604184

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 医学辞書を用いた用語間関係の自動抽出手法と用語の自動分類手法に関する研究2005

    • Author(s)
      荒牧英治, 今井健, 梶野正幸, 美代賢吾, 大江和彦
    • Journal Title

      医療情報学 25・6

      Pages: 463-474

    • NAID

      10022604285

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary 2006 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Takeshi Imai, Masayo Kashiwagi, Masayuki Kajino, Kengo Miyo, Kazuhiko Ohe : Toward Medical Ontology via Natural Language Processing2005

    • Author(s)
      Eiji Aramaki
    • Journal Title

      International Joint Conference on Natural Language Processing (IJCNLP) workshop OntoLex2005

      Pages: 53-58

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Toward Medical Ontology via Natural Language Processing2005

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Masayo Kashiwagi, Masayuki Kajino, Kengo Miyo, Kazuhiko Ohe
    • Journal Title

      International Joint Conference on Natural Language Processing (IJCNLP) workshop OntoLex2005

      Pages: 53-58

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 我が国の医療情報システムの方向性2005

    • Author(s)
      大江和彦
    • Journal Title

      映像情報Medical 37(13)

      Pages: 1347-1352

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 診断報告書における病理医から臨床医へのリクエスト表現の分析2005

    • Author(s)
      光石豊, 遠藤徹, 河添悦昌, 高田真美, 田中勝弥, 美代賢吾, 大江和彦
    • Journal Title

      医療情報学 25(Suppl)

      Pages: 688-691

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Mapping Japanese Medical Terms to UMLS Metathesaurus2004

    • Author(s)
      Y. Onogi, K. Ohe, M. Tanaka, A. Nozoe, T. Sakurai, M. Sato, Y. Kikuchi, T. Shinohara, H. Suzuki, S. Kaihara, Y. Setyama
    • Journal Title

      MEDINFO 2004 Proceedings of the II th World Congress on Medical Informatics

      Pages: 406-410

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 医療情報の標準化 : 個別規格の標準化から全体の標準化へ2004

    • Author(s)
      大江和彦
    • Journal Title

      映像情報Medical 36

      Pages: 1420-1424

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Mapping Japanese Medical Terms to UMLS Metathesaurus2004

    • Author(s)
      Y. Onogi, K. Ohe, M. Tanaka, A. Nozoe, T. Sakurai, M. Sato, Y. Kikuchi, T. Shinohara, H. Suzuki, S. Kaihara, Y. Setyama
    • Journal Title

      MEDINFO 2004 Proceedings of the II th World Congress on Medical Infnrmatics

      Pages: 406-410

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Mapping Japanese Medical Terms to UMLS Metathesaurus2004

    • Author(s)
      Y.Onogi, K.Ohe, M.Tanaka, A.Nozoe, T.Sakurai, M.Sato, Y.Kikuchi, T.Shinohara, H.Suzuki, S.Kaihara, Y.Setyama
    • Journal Title

      MEDINFO 2004 Proceedings of the IIth World Congress on Medical Informatics

      Pages: 406-410

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 医療情報の標準化:個別規格の標準化から全体の標準化へ2004

    • Author(s)
      大江和彦
    • Journal Title

      映像情報Medical 36

      Pages: 1420-1424

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 標準的電子カルテの考え方と機能モデル2004

    • Author(s)
      大江和彦
    • Journal Title

      新医療 31(7)

      Pages: 73-76

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 効果的な医学知識提供のための電子医学教科書のアクセス分析2004

    • Author(s)
      美代賢吾, 大江和彦
    • Journal Title

      医療情報学 24(suppl)

      Pages: 456-457

    • Related Report
      2004 Annual Research Report
  • [Journal Article] インシデント自由入力文からインシデント種別の自動分類の試み2004

    • Author(s)
      岩橋佑佳, 大江和彦
    • Journal Title

      医療情報学 24(suppl)

      Pages: 804-805

    • Related Report
      2004 Annual Research Report
  • [Presentation] A Statistical Selector of the Best among Multiple ICD-coding Methods2008

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Masayuki Kajino Kengo Miyo, Kazuhiko Ohe
    • Organizer
      MedInfo 2007
    • Place of Presentation
      オーストラリア・ブリスベン
    • Year and Date
      2008-08-21
    • Related Report
      2007 Annual Research Report
  • [Presentation] Orthographic Disambiguation Incorporating Transliterated Probability2008

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Kengo Miyo, Kazuhiko One
    • Organizer
      International Joint Conference on Natural Language Processing (IJCNLP2008)
    • Place of Presentation
      Mumbai, India.
    • Year and Date
      2008-01-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Support Vector Machine Based Orthographic Disambiguation2007

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Kengo Miyo, Kazuhiko Ohe
    • Organizer
      The Conference on Theoretical and Methodological Issues in Machine Translation (TMI2007)
    • Place of Presentation
      スエーデン・スコブデ
    • Year and Date
      2007-09-08
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Support Vector Machine Based Orthographic Disambiguation2007

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Kengo Miyo, Kazuhiko Ohe
    • Organizer
      The Conference on Theoretical and Methodological Issues in Machine Translation (TMT2007)
    • Place of Presentation
      Skovede, Sweden
    • Year and Date
      2007-09-08
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Statistical Selector of the Best Multiple ICD-coding Methods2007

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Masayuki Kajino Kengo Miyo, Kazuhiko Ohe
    • Organizer
      Medlnfo 2007
    • Place of Presentation
      オーストラリア・ブリスペン
    • Year and Date
      2007-08-21
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Finding Malignant Findings from Radiological Reports using Medical Attributes ans Syntactic Information2007

    • Author(s)
      Takeshi Imai, Eiji Aramaki, Masayuki Kajino, Kengo Miyo, Yuzo Onogi, Kazuhiko Ohe
    • Organizer
      Medlnfo 2007
    • Place of Presentation
      オーストラリア・ブリスペン
    • Year and Date
      2007-08-21
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Statistical Selector of the Best Multiple ICD-coding Methods2007

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Masayuki Kajino Kengo Miyo, Kazuhiko Ohe
    • Organizer
      Medlnfo 2007
    • Place of Presentation
      Brisbane, Australia
    • Year and Date
      2007-08-21
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Finding Malignant Findings from Radiological Reports using Medical Attributes ans Syntactic Information2007

    • Author(s)
      Takeshi Imai, Eiji Aramaki, Masayuki Kajino, Kengo Miyo, Yuzo Onogi, Kazuhiko Ohe
    • Organizer
      MedInfo 2007
    • Place of Presentation
      Brisbane, Australia
    • Year and Date
      2007-08-21
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Finding Malignant Findings from Radiological Reports using Medical Attributes ans Syntactic Informatio2007

    • Author(s)
      Takeshi Imai, Eiji Aramaki, Masayuki Kajino, Kengo Miyo, Yuzo Onogi, Kazuhiko Ohe
    • Organizer
      MedInfo 2007
    • Place of Presentation
      オーストラリア・ブリスベン
    • Year and Date
      2007-08-21
    • Related Report
      2007 Annual Research Report
  • [Presentation] Semantic Relation Classification using Physical Sizes2007

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Kengo Miyo, Kazuhiko Ohe
    • Organizer
      the Association for Computational Linguistics (ACL2007) Workshop on Semant ic Evaluations (SemEval 2007)
    • Place of Presentation
      チェコ・プラハ
    • Year and Date
      2007-06-23
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Semantic Relation Classification using Physical Sizes2007

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Kengo Miyo, Kazuhiko Ohe
    • Organizer
      the Association for Computational Linguistics (ACL2007) Workshop on Semantic Evaluations (SemEval 2007)
    • Place of Presentation
      Prague, Czech Renpublic.
    • Year and Date
      2007-06-23
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] UTH:SVM-based Semantic Relation Classification using Physical Sizes2007

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Kengo Miyo, Kazuhiko Ohe
    • Organizer
      the Association for Computational Linguistics (ACL 2007) Workshop on Semantic Evaluations (SemEval 2007)
    • Place of Presentation
      チェコ・プラハ
    • Year and Date
      2007-06-23
    • Related Report
      2007 Annual Research Report
  • [Presentation] 自然言語処理によるオントロジー構築支援の試みとその問題点2007

    • Author(s)
      荒牧英治, 今井健, 梶野正幸, 美代賢吾, 大江和彦
    • Organizer
      言語処理学会第13同年次大会(NLP2007)併設ワークショップ「言語的オントロジーの構築・連携・利用」
    • Place of Presentation
      大津
    • Year and Date
      2007-03-23
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 非文法的かつ断片化されたテキストからの頑健な情報抽出2007

    • Author(s)
      荒牧英治, 今井健, 美代賢吾, 大江和彦
    • Organizer
      言語処理学会第13回年次大会(NLP2007)
    • Place of Presentation
      大津
    • Year and Date
      2007-03-21
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Patient Status Classification by using Rule based Sentence Extraction and BM25-kNN based Classifier2006

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Kengo Miyo, Kazuhiko Ohe
    • Organizer
      Workshop on Challenges in Natural Language Processing for Clinical Data
    • Place of Presentation
      米国ソシレトンDC
    • Year and Date
      2006-11-14
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Automatic Deidentification by using Sentence Features and Label Consistency2006

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Kengo Miyo, Kazuhiko Ohe
    • Organizer
      Workshop on Challenges in Natural Language Processing for Clinical Data
    • Place of Presentation
      米国ワシントンDC
    • Year and Date
      2006-11-13
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Automatic Deidentification by using Sentence Features and Label Consistency2006

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Kengo Miyo, Kazuhiko Ohe
    • Organizer
      Workshop on Challenges in Natural Language Processing for Clinical Data
    • Place of Presentation
      Washington DC, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Patient Status Classification by using Rule based Sentence Extraction and BM25-KNN based Classifier2006

    • Author(s)
      Eiji Aramaki, Takeshi Imai, Kengo Miyo, Kazuhiko Ohe
    • Organizer
      Workshop on Challenges in Natural Language Processing for Clinical Data
    • Place of Presentation
      Washington DC, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Remarks]

    • URL

      http://www.m.u-tokyo.ac.jp/medinfo/

    • Related Report
      2007 Annual Research Report

URL: 

Published: 2004-04-01   Modified: 2016-04-21  

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