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New development in molecular genetic and molecular pharmacological studies on intractable intraocular inflammation.

Research Project

Project/Area Number 16209051
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Ophthalmology
Research InstitutionHOKKAIDO UNIVERSITY

Principal Investigator

OHNO Shigeaki  Hokkaido Univ., Grad. School of Med., Prof., 大学院医学研究科, 教授 (50002382)

Co-Investigator(Kenkyū-buntansha) YOSHIDA Kazuhiko  Hokkaido Univ., Hokkaido Univ. Hospital, Lec., 講師 (90281807)
NAMBA Kenichi  Hokkaido Univ., Grad. School of Med., Inst., 大学院医学研究科, 助手 (70333599)
MIZUKI Nobuhisa  Yokohama city Univ., Grad. School of Med., Prof., 医学部, 教授 (90336579)
INOKO Hidetoshi  Toukai Univ., Grad. School of Med., Prof., 医学部, 教授 (10101932)
ONOE Kazunori  Hokkaido Univ., Institute for Genetic Med., Prof., 遺伝子病制御研究所, 教授 (40002117)
田川 義継  北海道大学, 大学院・医学研究科, 助教授 (40109426)
Project Period (FY) 2004 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥50,310,000 (Direct Cost: ¥38,700,000、Indirect Cost: ¥11,610,000)
Fiscal Year 2006: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
Fiscal Year 2005: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
Fiscal Year 2004: ¥25,870,000 (Direct Cost: ¥19,900,000、Indirect Cost: ¥5,970,000)
Keywordsintractable intraocular inflammation / uveitis / microsatellite / pooled DNA / oxidative stress / 多型microsatellite / pooled DNA法 / ベーチェット病 / 原田病 / 一酸化窒素 / エンドトキシン / アロニア抽出物 / フコキサンチン / エンドトキシ / コキサンチン / 顆粒球吸着カラム
Research Abstract

Association analysis was carried out for the Behcet's disease and the Vogt-Koyanagi-Harada (VKH) disease. In the 23,465 microsatellite markers on whole genome, 147 markers (0.63%) was picked up as susceptible genes areas of the Behcet's disease. In the VKH disease, which is the popular uveitis in Japan, is known about the strong association with HLA-DR area. However, other association area is detected on the long arm of chromosome 6. We are now analyzing the functions of this area.
In refractory intraocular inflammation groups, nitric oxide levels in the aqueous humor and blood were significantly higher than that in the control group. On the other hand, Treatment with antioxidative compounds significantly suppressed ocular inflammation. The results indicate that these compounds show a significant anti-inflammatory effect. For instance, Treatment with the crude extract by blue honeysuckle, the flora of north countries, has a strong anti-oxidative effect, significantly suppressed inflammation in refractory intraocular inflammation model in a dose-dependent manner.
Immunomodulatory granulocytapheresis therapy was revealed to be significantly effective to reduce frequency of light threatening ocular inflammatory attacks in Behcet's disease. And it was also indicated that this therapy was effective in the patient especially with less than 5 years duration of the disease from onset.

Report

(4 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • Research Products

    (133 results)

All 2007 2006 2005 2004 Other

All Journal Article (131 results) Book (2 results)

  • [Journal Article] Association of heal shock protein 70 induction and the amelioration of experimental autoimmune uveoretinitis in mice.2007

    • Author(s)
      Kitamei H
    • Journal Title

      Immunobiology 212・5

      Pages: 11-18

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Association of heat shock protein 70 induction and the amelioration of experimental autoimmune uveoretinitis in mice.2007

    • Author(s)
      Kitamei H
    • Journal Title

      Immunobiology 212

      Pages: 11-18

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effect of p75NTR on the regulation of photoreceptor apoptosis in the rd mouse.2007

    • Author(s)
      Nakamura K
    • Journal Title

      Molecular Vision (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Expression of cyclin D1 in the developing lens of c-maf -/- mice.2007

    • Author(s)
      Kase S
    • Journal Title

      Acta Histochemica (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Association of heat shock protein 70 induction and the amelioration of experimental autoimmune uveoretinitis in mice.2007

    • Author(s)
      Kitamei H
    • Journal Title

      Immunobiology 212・5

      Pages: 11-18

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Elevation of serum KL-6 levels in patients with tubulointerstitial nephritis and uveitis (TINU) syndrome.2006

    • Author(s)
      Kase S
    • Journal Title

      Am J Kidney Dis 48・6

      Pages: 935-941

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Epstein-Barr virus-infected cells in the aqueous humor originated from nasal NK/T cell lymphoma.2006

    • Author(s)
      Kase S
    • Journal Title

      Br J Ophthalmol 90・2

      Pages: 244-245

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Increased expression of mucinous glycoprotein KL-6 in human pterygium.2006

    • Author(s)
      Kase S
    • Journal Title

      Br J Ophthalmol 90・9

      Pages: 1208-1209

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Acute unilateral conjunctivitis after rubella vaccination : the detection of the rubella genome in the inflamed conjunctiva by reverse transcriptase-polymerase-chain reaction.2006

    • Author(s)
      Kitaichi N
    • Journal Title

      Br J Ophthalmol 90・11

      Pages: 1436-1437

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Increase in macrophage migration inhibitory factor levels in lacrimal fluid of patients with severe atopic dermatitis.2006

    • Author(s)
      Kitaichi N
    • Journal Title

      Graefe's Arch Clin Exp Ophthalmol 244・7

      Pages: 825-828

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Amelioration of experimental autoimmune uveoreitinitis (EAU) with an ininhibitor of nuclear factor kappa B (NF-kappaB), pyrrolidine dithiocarbamate.2006

    • Author(s)
      Kitamei M
    • Journal Title

      J Leukocyte Biol 79・6

      Pages: 1193-1201

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Phosphorylation of p27 (KIP1) in the mitotic cells of the corneal epithelium.2006

    • Author(s)
      Kase S
    • Journal Title

      Curr Eye Res 31・4

      Pages: 307-312

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Usefulness of quantiyfying serum KL-6 levels in the follow-up of uveitic patients with sarcoidosis.2006

    • Author(s)
      Kitaichi N
    • Journal Title

      Graefe' s Arch Clin Exp Ophthalmol 244・4

      Pages: 433-437

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Immunolocalization of cyclin D1 in the develoing lens of c-maf-/-mice.2006

    • Author(s)
      Kase S
    • Journal Title

      Acta Histochem 107・6

      Pages: 469-472

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Expression of cdc2 and p27 (KIP1) phosphorylation in mitotic cells of the human retinoblastoma.2006

    • Author(s)
      Kase S
    • Journal Title

      Int J Mol Med 17・3

      Pages: 465-468

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role of apoptosis signal-regulating kinase 1 in stress-induced neural cell apoptosis in vivo.2006

    • Author(s)
      Harada C
    • Journal Title

      Am J Pathol 168・1

      Pages: 261-269

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Expression of glutamine synthetase and cell proliferation in human idiopathic epiretinal membrane.2006

    • Author(s)
      Kase S
    • Journal Title

      Ophthalmol 90・1

      Pages: 96-98

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Phosphorylation of extracellular signal-regulated kinase and p27 (KIP1) after retinal detachment.2006

    • Author(s)
      Kase S
    • Journal Title

      Graefe' s Arch Clin Exp Ophthalmol 244・3

      Pages: 352-358

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Captopril suppresses inflammation in endotoxin-induced uveitis in rats.2006

    • Author(s)
      Ilieva I
    • Journal Title

      Exp Eye Res 83・3

      Pages: 651-657

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] アレルギー性結膜炎の診断と治療.2006

    • Author(s)
      合田千穂
    • Journal Title

      アレルギー 55・7

      Pages: 791-793

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] 増殖糖尿病網膜症の硝子体手術成績と手術適応の検討.2006

    • Author(s)
      村松昌裕
    • Journal Title

      日本眼科学会雑誌 110・12

      Pages: 950-960

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] HLAとは?2006

    • Author(s)
      竹本裕子
    • Journal Title

      あたらしい眼科 23・12

      Pages: 1515-1519

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Elevation of serum KL-6 levels in patients with tubulointerstitial nephritis and uveitis (TINU) syndrome.2006

    • Author(s)
      Kase S, Kitaichi N, Namaba K, Miyazaki A, Yoshida K, Ishikura K, Ikeda M, Nakashima T, Ohno S
    • Journal Title

      Am J Kidney Dis 48

      Pages: 935-941

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Epstein-Barr virus-infected cells in the aqueous humor originated from nasal NK/T cell lymphoma.2006

    • Author(s)
      Kase S, Namba K, Kitaichi N, Ohno S
    • Journal Title

      Br J Ophthalmol 90

      Pages: 244-5

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Increased expression of mucinous glycoprotein KL-6 in human pterygium.2006

    • Author(s)
      Kase S, Kitaichi N, Furudate N, Yoshida K, Ohno S
    • Journal Title

      Br J Ophthalmol 90

      Pages: 1208-1209

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Acute unilateral conjunctivitis after rubella vaccination : the detection of the rubella genome in the inflamed conjunctiva by reverse transcriptase-polymerase-chain reaction.2006

    • Author(s)
      Kitaichi N, Ariga T, Ohno S, Shimizu T
    • Journal Title

      Br J Ophthalmol 90

      Pages: 1436-1437

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Increase in macrophage migration inhibitory factor levels in lacrimal fluid of patients with severe atopic dermatitis.2006

    • Author(s)
      Kitaichi N, Shimizu T, Honda A, Abe R, Ohgami K, Shiratori K, Shimizu H, Ohno S
    • Journal Title

      Graefe' s Arch Clin Exp Ophthalmol 244

      Pages: 825-828

    • NAID

      120000964444

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Amelioration of experimental autoimmune uveoreitinitis (EAU) with an ininhibitor of nuclear factor kappa B (NF-kappaB), pyrrolidine dithiocarbamate.2006

    • Author(s)
      Kitamei M, Iwabuchi K, Namba K, Yoshida K, Yanagawa Y, Kitaichi N, Kitamura M, Ohno S, Onoe K
    • Journal Title

      J Leukocyte Biol 79

      Pages: 1193-1201

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Phosphorylation of p27 (KIP1) in the mitotic cells of the corneal epithelium.2006

    • Author(s)
      Kase S, Yoshida K, Ohgami K, Shiratori K, Nakayama K I, Ohno S
    • Journal Title

      Curr Eye Res 31

      Pages: 307-312

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Usefulness of quantiyfying serum KL-6 levels in the follow-up of uveitic patients with sarcoidosis.2006

    • Author(s)
      Kitaichi N, Ariga T, Kase S, Yoshida K, Namba K, Ohno S
    • Journal Title

      Graefe's Arch Clin Exp Ophthalmol 244

      Pages: 433-437

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Immunolocalization of cyclin D1 in the develoing lens of c-maf-/-mice.2006

    • Author(s)
      Kase S, Yoshida K, Sakai M, Ohgami K, Shiratori K, Kitaichi N, Suzuki Y, Harada T, OhnO S
    • Journal Title

      Acta Histochem 107

      Pages: 469-472

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Expression of cdc2 and p27 (KIP1) phosphorylation in mitotic cells of the human retinoblastoma.2006

    • Author(s)
      Kase S, Yoshida K, Ohgami K, Shiratori K, Suzuki Y, Nakayama K, Ohno S
    • Journal Title

      Int J Mol Med 17

      Pages: 465-468

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role of apoptosis signal-regulating kinase 1 in stress-induced neural cell apoptosis in vivo.2006

    • Author(s)
      Harada C, Nakamura K, Namekata K, Okumura A, Mitamura Y, lizuka Y, Kashiwagi K, Yoshida K, Ohno S, Matsuzawa A, Tanaka K, Ichijo H, Harada T
    • Journal Title

      Am J Pathol 168

      Pages: 261-269

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Expression of glutamine synthetase and cell proliferation in human idiopathic epiretinal membrane.2006

    • Author(s)
      Kase S, Saito W, Yokoi M, Yoshida K, Furudate N, Muramatsu M, Saito A, Kase M, Ohno S
    • Journal Title

      Br J Ophthalmol 90

      Pages: 96-98

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Phosphorylation of extracellular signal-regulated kinase and p27 (KIP1) after retinal detachment.2006

    • Author(s)
      Kase S, Yoshida K, Harada T, Harada C, Namekata K, Suzuki Y, Ohgami K, Shiratori K, Nakayama K, Ohno S
    • Journal Title

      Graefe' s Arch Clin Exp Ophthalmol 244

      Pages: 352-358

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Captopril suppresses inflammation in endotoxin-induced uveitis in rats.2006

    • Author(s)
      Ilieva I, Ohgami K, Jin X H, Suzuki Y, Shiratori K, Yoshida K, Kase S, Ohno S
    • Journal Title

      Exp Eye Res 83

      Pages: 651-657

    • NAID

      120000964230

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Elevation of serum KL-6 levels in patients with tubulointerstitial mephritis and uveitis (TINU) syndrome.2006

    • Author(s)
      Kase S
    • Journal Title

      Am J Kidney Dis 48・6

      Pages: 935-941

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Increase in macrophage migration inhibitory factor levels in lacrimal fluid of patients with severe atopic dermatitis2006

    • Author(s)
      Kitaichi N
    • Journal Title

      Graefe's Arch Clin Exp Ophthalmol 244・7

      Pages: 825-828

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Amelioration of experimental autoimmune uveoreitinitis (EAU) with an ininbitor of nuclear factor kappa B (NF-kappaB), pyrrolidine dithiocarbamate.2006

    • Author(s)
      Kitamei M
    • Journal Title

      J Leukocyte Biol 79・6

      Pages: 1193-1201

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Phosphorylation of p27 (KIPI) in the mitotic cells of the corneal epithelium.2006

    • Author(s)
      Kase S
    • Journal Title

      Curr Eye Res 31・4

      Pages: 307-312

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Expression of cdc2 and p27 (KIPI) phosphorylation in mitotic cells of the human retinoblastoma.2006

    • Author(s)
      Kase S
    • Journal Title

      Int J Mol Med 17・3

      Pages: 465-468

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Phosphorylation of extracellular signal-regulated kinase and p27 (KIPI) after retinal detachment.2006

    • Author(s)
      Kase S
    • Journal Title

      Graefe' s Arch Clin Exp Ophthalmol 244・3

      Pages: 352-358

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Captopril suppresses inflammation in endotoxin-induced uveitis in rats.2006

    • Author(s)
      Ilieva I
    • Journal Title

      Exp Eye Res 83 ? 3

      Pages: 651-657

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Suppressive effects of astaxanthin against rat endotoxin-induceduveitis by inhibiting the NF-<kappa>B signaling pathway.2006

    • Author(s)
      Suzuki Y
    • Journal Title

      Expeimental Eye Research 82

      Pages: 275-281

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Effects of blue honeysuckle (Lonicera caerulea L.) extract on lipopolysaccharideinduced inflammation in vitro and in vivo.2006

    • Author(s)
      Jin XH
    • Journal Title

      Expeimental Eye Research 82

      Pages: 860-867

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Immunolocalization of cyclin D1 in the develoing lens of c-maf-/-mice.2006

    • Author(s)
      Kase S
    • Journal Title

      Acta Histochem 107

      Pages: 469-472

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Expression of cdc2 and p27(KIP1) phosphorylation in mitotic cells of the human retinoblastoma.2006

    • Author(s)
      Kase S
    • Journal Title

      Int J Mol Med 17

      Pages: 465-468

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Role of apoptosis signal-regulating kinase 1 in stress-induced neural cell apoptosis in vivo.2006

    • Author(s)
      Harada C
    • Journal Title

      American Journal of Pathology 168

      Pages: 261-269

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Expression of glutamine synthetase and cell proliferation in human idiopathic epiretinal membrane.2006

    • Author(s)
      Kase S
    • Journal Title

      British Journal of Ophthalmology 90

      Pages: 96-98

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Expression of thymidine phosphorylase in choroidal malignant melanoma associated with neovascular glaucoma.2005

    • Author(s)
      Kase S
    • Journal Title

      Pathol Int 55・9

      Pages: 569-573

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Bilateral diffuse uveal melanocytic proliferation in a patient with cancer-associated retinopathy.2005

    • Author(s)
      Saito W
    • Journal Title

      Am J Ophthalmol 140・5

      Pages: 942-945

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Expression of p27(KIP1) and cell proliferation in human retina and retinoblastoma.2005

    • Author(s)
      Kase S
    • Journal Title

      Anticancer Res 25・6

      Pages: 3843-3846

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of fucoxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo.2005

    • Author(s)
      Shiratori K
    • Journal Title

      Exp Eye Res 81・4

      Pages: 422-428

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The effects of naringin and naringenin on endotoxin-induced uveitis in rats.2005

    • Author(s)
      Shiratori K
    • Journal Title

      J Ocul Pharmacol Ther 21・4

      Pages: 298-304

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Phosphorylation of p27(KIP1) in the developing retina and retinoblastoma.2005

    • Author(s)
      Kase S
    • Journal Title

      Int J Mol Med 16・2

      Pages: 257-262

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Disappearance of p27(KIP1) and increase in proliferation of the lens cells after extraction of most of the fiber cells of the lens.2005

    • Author(s)
      Kase S
    • Journal Title

      Cur Eye Res 30・6

      Pages: 437-442

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] A patient with sarcoidosis diagnosed by a biopsy of scleral nodules.2005

    • Author(s)
      Saito W
    • Journal Title

      Graefe' s Arch Clin Exp Ophthalmol 243・4

      Pages: 374-376

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role of neurotrophin-4/5 in neural cell death during retinal development and ischemic retinal injury in vivo.2005

    • Author(s)
      Harada C
    • Journal Title

      Invest Ophthalmol Vis Sci 46・2

      Pages: 669-673

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Anti-inflammatory effects of aronia extract on rat endotoxin-induced uveitis.2005

    • Author(s)
      Ohgami K
    • Journal Title

      Invest Ophthalmol Vis Sci 46・1

      Pages: 275-281

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Central Serous Retinal Detachment Detected by Optical Coherence Tomography in Leber's Idiopathic Stellate Neuroretinitis.2005

    • Author(s)
      Ando R
    • Journal Title

      Jpn J Ophthalmol 49・6

      Pages: 547-548

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] アレルギー性眼疾患を巡る最近の話題.2005

    • Author(s)
      合田千穂
    • Journal Title

      日本醫事新報 4261

      Pages: 7-11

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] アレルギー性結膜疾患.2005

    • Author(s)
      合田千穂
    • Journal Title

      アレルギー科 20

      Pages: 138-141

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] アスタキサンチンの調節機能および疲れ眼におよぼす影響-健常成人を対象とした摂取量設定試験.2005

    • Author(s)
      新田卓也
    • Journal Title

      臨床医薬 21・5

      Pages: 543-556

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] アスタキサンチンの過剰摂取における安全性の検討.2005

    • Author(s)
      大神一浩
    • Journal Title

      臨床医薬 21・6

      Pages: 651-659

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 眼疾患の外因と内因.2005

    • Author(s)
      大野重昭
    • Journal Title

      日本眼科学会雑誌 109

      Pages: 885-916

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] ベーチェット病患者を対象とした抗TNFα抗体の前期第II相臨床試験成績.2005

    • Author(s)
      中村聡
    • Journal Title

      臨眼 59・10

      Pages: 1685-1689

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] アレルギー性結膜疾患ガイドラインの話題.2005

    • Author(s)
      南場研一
    • Journal Title

      Allergia Trends 7・3

      Pages: 10-13

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Behcet病2005

    • Author(s)
      北市伸義
    • Journal Title

      日本臨床 63・5

      Pages: 376-380

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Expression of thymidine phosphorylase in choroidal malignant melanoma associated with neovascular glaucoma.2005

    • Author(s)
      Kase S, Saito W, Yoshida K, Namba K, Osaki M, Ohgami K, Shiratori K, Kitaichi N, Adachi H, Ito H, Ohno S
    • Journal Title

      Pathol Int 55

      Pages: 569-573

    • NAID

      10019344364

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Bilateral diffuse uveal melanocytic proliferation in a patient with cancer-associated retinopathy.2005

    • Author(s)
      Saito W, Kase S, Yoshida K, Ohguro H, Kinoshita H, Yokoi M, Iwaki H, Ohno S:
    • Journal Title

      Am J Ophthalmol 140

      Pages: 942-945

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Expression of p27(KIP1)1 and cell proliferation in human retina and retinoblastoma.2005

    • Author(s)
      Kase S, Yoshida K, Ohgami K, Shiratori K, Harada T, Ohno S
    • Journal Title

      Anticancer Res 25

      Pages: 3843-3846

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of fucoxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo.2005

    • Author(s)
      Shiratori K, Ohgami K, Ilieva B.I, Xue-Hai Jin, KoyamaY, MiyashitaK, YoshidaK, Kase1 S, Ohno S
    • Journal Title

      Exp Eye Res 81

      Pages: 422-428

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The effects of naringin and naringenin on endotoxin-induced uveitis in rats.2005

    • Author(s)
      Shiratori K, Ohgami K, Ilieva B.I, Jin, Yoshida K, Kase S, Ohno S:
    • Journal Title

      J Ocul Pharmacol Ther 21

      Pages: 298-304

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Phosphorylation of p27(KIP1) in the developing retina and retinoblastoma.2005

    • Author(s)
      Kase S, Yoshida K, Nakayama I K, Nakayama K, Ikeda H2, Harada T, Harada C, Ohgami K, Shiratori K, Ohno S
    • Journal Title

      Int J Mol Med 16

      Pages: 257-262

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Disappearance of p27(KIP1) and increase in proliferation of the lens cells after extraction of most of the fiber cells of the lens.2005

    • Author(s)
      Kase S, Ikeda H, Harada T, Harada C, Imaki J, Ohgami K, Shiratori K, Nakayama K I., Nakayama K, Ohno S, Yoshida K:
    • Journal Title

      Cur Eye Res 30

      Pages: 437-442

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] A patient with sarcoidosis diagnosed by a biopsy o scleral nodules.2005

    • Author(s)
      Saito W, Kotake S, Ohno S
    • Journal Title

      Graefe' s Arch Clin Exp Ophthalmol 243

      Pages: 374-376

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Role of neurotrophin-4/5 in neural cel death during retinal development and ischemic retinal injury in vivo.2005

    • Author(s)
      Harada C, Harada T, Hun-Meng A.Q, Namekat K, Yoshida K, Ohno S, Tanaka K, L.F.Parada
    • Journal Title

      Invest Ophthalmol Vis Sci 46

      Pages: 669-673

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Anti-inflammatory effects of aroni extract on rat endotoxin-induced uveitis.2005

    • Author(s)
      Ohgami K, Ilieva B.I, Shiratori K, Koyama Y, Xue-Hai Jin, Yoshida K, Kase S, Kitaich N, Suzuki Y, Tanaka T, Ohno S
    • Journal Title

      Invest Ophthalmol Vis Sci 46

      Pages: 275-281

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Central Serous Retina Detachment Detected by Optical Coherence Tomography in Leber's Idiopathic Stellate Neuroretinitis.2005

    • Author(s)
      Ando R, Shinmei Y, Nitta T, Yoshida K, Chin S, Kase M, Ohno S
    • Journal Title

      Jpn J Ophthalmol 49

      Pages: 547-548

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Clinical features in tubulointerstitial nephritis and uveitis (TINU) syndrome.2005

    • Author(s)
      Goda C
    • Journal Title

      American Journal of Ophthalmology 140

      Pages: 637-641

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Long-term evaluation of visual field alteration in Leber s hereditary optic neuroathy with visual recovery.2005

    • Author(s)
      Naka M
    • Journal Title

      Neuro Ophthalmol 29

      Pages: 65-67

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Phosphorylation of extracellular signal-regulated kinase and p27(KIP1) after retinal detachment.2005

    • Author(s)
      Kase S
    • Journal Title

      Graefes Arch Clin Exp Ophthalmol 2

      Pages: 1-7

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Expression of thymidine phosphorylase in choroidal malignant melanoma associated with neovascular glaucoma.2005

    • Author(s)
      Kase S
    • Journal Title

      Pathol Int 55

      Pages: 569-573

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Bilateral diffuse uveal melanocytic proliferation in a patient with cancer-associated retinopathy.2005

    • Author(s)
      Saito W
    • Journal Title

      American Journal of Ophthalmology 140

      Pages: 942-945

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Expression of p27(KIP1) and cell proliferation in human retina and retinoblastoma.2005

    • Author(s)
      Kase S
    • Journal Title

      Anticancer Research 25

      Pages: 3843-3846

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Effects of fucoxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo.2005

    • Author(s)
      Shiratori K
    • Journal Title

      Expeimental Eye Research 81

      Pages: 422-428

    • Related Report
      2005 Annual Research Report
  • [Journal Article] The effects of naringin and naringenin on endotoxin-induced uveitis in rats.2005

    • Author(s)
      Shiratori K
    • Journal Title

      J Ocul Pharmacol Ther 21

      Pages: 298-304

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Phosphorylation of p27(KIP1) in the developing retina and retinoblastoma.2005

    • Author(s)
      Kase S
    • Journal Title

      Int J Mol Med 16

      Pages: 257-262

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Comparative study of two sets of criteria for the diagnosis of Vogt-Koyanagi-Harada s disease : Comparative study of two sets of criteria for the diagnosis of Vogt-Koyanagi-Harada s disease.2005

    • Author(s)
      Kitamura M
    • Journal Title

      American Journal of Ophthalmology 139

      Pages: 1080-1085

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Disappearance of p27(KIP1) and increase in proliferation of the lens cell after extraction of most of the fiber cells of the lens.2005

    • Author(s)
      Kase S
    • Journal Title

      Current Eye Research 30

      Pages: 437-442

    • Related Report
      2005 Annual Research Report
  • [Journal Article] A patient with sarcoidosis diagnosed by a biopsy of scleral nodules.2005

    • Author(s)
      Saito W
    • Journal Title

      Graefes Arch Clin Exp Ophthalmol 243

      Pages: 374-376

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Role of neurotrophin-4/5 in neural cell death during retinal development and ischemic retinal injury in vivo.2005

    • Author(s)
      Harada C
    • Journal Title

      Invest Ophthalmol Vis Sci 46

      Pages: 669-673

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Anti-inflammatory effects of aronia extract on rat endotoxin-induced uveitis.2005

    • Author(s)
      Ohgami K
    • Journal Title

      Invest Ophthalmol Vis Sci 46

      Pages: 275-281

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Usefulness of quantifying serum KL-6 levels in the follow-up of uveitic patients with sarcoidosis.2005

    • Author(s)
      Kitaichi N
    • Journal Title

      Graefes Arch Clin Exp Ophthalmol 23

      Pages: 1-5

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Inducible immune regulation following autoimmune disease in the immune privileged eye.2005

    • Author(s)
      Kitaichi N, Namba K, Taylor AW
    • Journal Title

      J Leuokoc Biol 77・4(印刷中)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Comparative study of two sets of criteria for the diagnosis of Vogt-Koyanagi-Harada's disease2005

    • Author(s)
      Kitamura M, Takami K, Kitaichi N, Namba K, Kitamei H, Kotake S, Ohno
    • Journal Title

      Am J Ophthalmol 139(印刷中)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Anti-inflammatory Effects of Aronia Extract on Rat Endotoxin-Induced Uveitis2005

    • Author(s)
      Ohgami K, Ilieva I, Shiratori K, Koyama Y, Jin XH, Yoshida K, Kase S, Kitaichi N, Suzuki Y, Tanaka T, Ohno S.
    • Journal Title

      Invest Ophthalmol Vis Sci 46・1

      Pages: 275-281

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Predominance of infiltrating IL-4 producing T cells in conjunctiva of patients with allergic conjunctival disease.2004

    • Author(s)
      Matsuura N
    • Journal Title

      Curr Eye Res 29・4

      Pages: 235-243

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Efficacy, safety, and pharmacokinetics of multiple administration of infliximab in Behcet's disease with refractory uveoretinitis.2004

    • Author(s)
      Ohno S
    • Journal Title

      J Rheumatol 31・7

      Pages: 1362-1368

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The effects of Ginkgo Biloba Extract on Lipopolysaccharide-induced inflammation in vitro and in vivo.2004

    • Author(s)
      Ilieva B. I
    • Journal Title

      Exp Eye Res 79・2

      Pages: 181-187

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Involvement of p27KIP1 in the proliferation of the developing corneal endothelium.2004

    • Author(s)
      Yoshida K
    • Journal Title

      Invest Ophthalmol Vis Sci 45・7

      Pages: 2163-2167

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Distribution of p27(KIP1), cyclin D1, and proliferating cell nuclear antigen after retinal detachment.2004

    • Author(s)
      Yoshida K
    • Journal Title

      Graefe's Arch Clin Exp Ophthalmol 242・5

      Pages: 437-441

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Involvement of p27(KIP1) in proliferation of the retinal pigment epithelium and ciliary body.2004

    • Author(s)
      Yoshida K
    • Journal Title

      Anat Embryol (BerlMar 9) 208・2

      Pages: 145-150

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Inhibition of endotoxin-induced uveitis and potentiation of cyclooxygenase-2 protein expression by alpha-melanocyte-stimulating hormone.2004

    • Author(s)
      Shiratori K
    • Journal Title

      Invest Ophthalmol Vis Sci 45・1

      Pages: 159-164

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The cotton rat model for adenovirus ocular infection : antiviral activity of cidofovir.2004

    • Author(s)
      Kaneko H
    • Journal Title

      Antivir Res 61・1

      Pages: 63-66

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Anti-inflammatory effects of alpha-melanocyte-stimulating hormone against rat endotoxin-induced uveitis and the time course of inflammatory agents in aqueous humor.2004

    • Author(s)
      Nishida T
    • Journal Title

      Int Immunopharmacol 4・8

      Pages: 1059-1066

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Diverse NF-κB expression in epiretinal membranes after human diabetic retinopathy and proliferative vitreoretinopathy.2004

    • Author(s)
      Harada C
    • Journal Title

      Molecular Vision 10・1

      Pages: 31-36

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 血管内リンパ腫による仮面症候群の1例.2004

    • Author(s)
      岩田大樹
    • Journal Title

      臨眼 58・13

      Pages: 2307-2344

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] シクロスポリン療法施行中に視神経乳頭浮腫を呈した小児皮膚筋炎の1例.2004

    • Author(s)
      戸板成昭
    • Journal Title

      小児科臨床 57・6

      Pages: 1111-1114

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 相対的求心性瞳孔障害が陽性となったacute zonal occult outer retinopathyの1例.2004

    • Author(s)
      高橋理美
    • Journal Title

      臨眼 58・6

      Pages: 983-985

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 移動性網膜下液を伴った後部強膜炎の1例.2004

    • Author(s)
      森祥平
    • Journal Title

      臨眼 58・13

      Pages: 2313-2316

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Vogt-小柳-原田病新鮮例に対するステロイド大量療法とパルス療法の比較.2004

    • Author(s)
      北明大洲
    • Journal Title

      臨眼 58・3

      Pages: 369-372

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 特集 川崎病Q&A 川崎病の結膜充血における眼科的な特徴を教えてください。2004

    • Author(s)
      北明大洲
    • Journal Title

      小児内科 35・9

      Pages: 1506-1507

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Predominance of infiltrating IL-4 producing T cells in conjunctiva of patients with allergic conjunctival disease.2004

    • Author(s)
      Matsuura N, Uchio E, Nakazawa M, Yago T, Matsumoto S, Ohno S, Minami M
    • Journal Title

      Curr Eye Res 29

      Pages: 235-243

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Efficacy, safety, and pharmacokinetics of multiple administration of infliximab in Behcet' disease with refractory uveoretinitis.2004

    • Author(s)
      Ohno S, Nakamura S, Hori S, Shimakawa M, Kawashima H, Mochizuki M, Sugita S, Uenc S, Yoshizaki K, Inaba G
    • Journal Title

      J Rheumatol 31

      Pages: 1362-1368

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The effects of Ginkgo Biloba Extract on Lipopolysaccharide-inducec inflammation in vitro and in vivo.2004

    • Author(s)
      Ilieva B.I, Ohgami K, Shiratori K, Koyama Y, Yoshida K, KitameiH, Takemoto Y, Yazawa K, Ohno S
    • Journal Title

      Exp Eye Res 79

      Pages: 181-187

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Involvement of p27KIP1 in the proliferation of the developing corneal endothelium.2004

    • Author(s)
      Yoshida K, Kase S, Nakayama K, Nagahama H, Harada T, Ikeda H, Harada C, Imaki J, Ohgami K, Shiratori K, Iliyana B I, Ohno S, Nishi S, Nakayama K I
    • Journal Title

      Invest Ophthalmol Vis Sci 45

      Pages: 2163-2167

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Distribution of p27(KIP1), cyclin D1, and proliferating cell nuclear antigen after retinal detachment.2004

    • Author(s)
      Yoshida K, Kase S, Nakayama K, Nagahama H, Harada T, Ikeda H, Harada C, Imaki J, Ohgami K, Shiratori K, Ohno S, Nakayama KI
    • Journal Title

      Graefe' s Arch Clin Exp Ophthalmol 242

      Pages: 437-441

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Involvement of p27(KIP1) in proliferation of the retinal pigment epithelium and ciliary body.2004

    • Author(s)
      Yoshida K, Nakayama K, Kase S, Nagahama H, Harada T, Ikeda H, Harada C, Imaki J, Ohgami K, Shiratori K, Ohno S, Nishi S, Nakayama KI
    • Journal Title

      Anat Embryol (BerlMar 9)

      Pages: 145-150

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Inhibition of endotoxin-induced uveitis and potentiation of cyclooxygenase-2 protein expression by alpha-melanocyte-stimulating hormone.2004

    • Author(s)
      Shiratori K, Ohgami K, Ilieva IB, Koyama Y, Yoshida K, Ohno S
    • Journal Title

      Invest Ophthalmol Vis Sci 45

      Pages: 159-164

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The cotton rat model for adenovirus ocular infection : antiviral activity of cidofovir.2004

    • Author(s)
      Kaneko H, Mori S, Suzuki 0, Iida T, Shigeta S, Abe M, Ohno S, Aoki K, Suzutani T
    • Journal Title

      Antivir Res 61

      Pages: 63-66

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Anti-inflammatory effects of alpha-melanocyte-stimulating hormone against rat endotoxin-induced uveitis and the time course of inflammatory agents in aqueous humor.2004

    • Author(s)
      Nishida T, Miyata S, Itoh Y, Mizuki N, Ohgami K, Shiratori K, Iliyana B I, Ohno S, Andrew W T
    • Journal Title

      Int Immunopharmacol 4

      Pages: 1059-1066

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Diverse NF-κ B expression in epiretinal membranes after human diabetic retinopathy and proliferative vitreoretinopathy.2004

    • Author(s)
      Harada C, Harada T, Mitamura Y, Quah AH-M, Ohtsuka K, Kotake S, Ohno S, Wada K, Takeuchi S, Tanaka K
    • Journal Title

      Molecular Vision 10

      Pages: 31-36

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 血管内リンパ腫による仮面症候群の1例2004

    • Author(s)
      岩田大樹, 南場研一, 東こずえ, 小竹 聡, 大野重昭
    • Journal Title

      臨床眼科 58・13

      Pages: 2307-2311

    • Related Report
      2004 Annual Research Report
  • [Journal Article] The effects of Ginkgo Biloba Extract on Lipopolysaccharide-induced inflammation in vitro and in vivo2004

    • Author(s)
      Ilieva B.I, Ohgami K, Shiratori K, Koyama Y, Yoshida K, Kitamei H, Takemoto Y, Yazawa K, Ohno S
    • Journal Title

      Experimental Eye Research 79・2

      Pages: 181-187

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Inhibition of endotoxin-induced uveitis and potentiation of cyclooxygenase-2 protein expression by alpha-melanocyte-stimulating hormone.2004

    • Author(s)
      Shiratori K, Ohgami K, Ilieva IB, Koyama Y, Yoshida K, Ohno S.
    • Journal Title

      Invest Ophthalmol Vis Sci 45・1

      Pages: 159-164

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Effect of p75NTR on the regulation of photoreceptor apoptosis in the rd mouse.

    • Author(s)
      Nakamura K
    • Journal Title

      Molecular Vision (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Expression of cyclin D1 in the developing lens of c-maf -/-mice.

    • Author(s)
      Kase S
    • Journal Title

      Acta Histochemica (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effect of p75NTR on the regulation of photoreceptor apoptosis in the rd mouse.

    • Author(s)
      Nakamura K, Harada C, Okumura A, Namekata K, Mitamura Y, Yoshida K, Ohno S, Yoshida H, Harada T
    • Journal Title

      Molecular Vision (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Expression of cyclin D1 in the developing lens of c-maf-/-mice.

    • Author(s)
      Kase S, Yoshida K, Sakai M, Ohgami K, Shiratori K, Kitaichi N, Suzuki Y, Harada T, Ohno S
    • Journal Title

      Acta Histochemica (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effects of fucoxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo

    • Author(s)
      Kenji Shiratori, Kazuhiro Ohgami, Iliyana Ilieva, MD, Xue-Hai Jin, Yoshikazu Koyama, Kazuo Miyashita, Kazuhiko Yoshida, Satoru Kase, Shigeaki Ohno
    • Journal Title

      Experimental Eye Research in press

    • Related Report
      2004 Annual Research Report
  • [Book] Behcet病に対するシクロスポリン治療2006

    • Author(s)
      大野重昭
    • Total Pages
      271
    • Publisher
      医薬ジャーナル社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Book] 網膜ぶどう膜炎.新・病気とからだの読本 7.眼と耳と鼻の病気2005

    • Author(s)
      大野重昭
    • Total Pages
      380
    • Publisher
      暮らしの手帖社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary

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Published: 2004-04-01   Modified: 2021-09-01  

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