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Community-based randomized controlled trial on risk reduction for cardiovascular disease by therapeutic life-style change

Research Project

Project/Area Number 16300218
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied health science
Research InstitutionHokkaido University

Principal Investigator

KAWAGUCHI Akito  Hokkaido Univ. Grad.School of Edu., Prof., 大学院教育学研究科, 教授 (70214608)

Co-Investigator(Kenkyū-buntansha) MORIYA Kiyoshi  Hokkaido Univ. Grad.School of Edu., Prof., 大学院教育学研究科, 教授 (40000939)
YANO Tokuo  Hokkaido Univ. Grad.School of Edu., Prof., 大学院教育学研究科, 教授 (80200559)
SUDA Tsutomu  Hokkaido Univ. Grad.School of Edu., Prof., 大学院教育学研究科, 教授 (90091470)
KIMURA Makoto  Hokkaido Univ. Ctr of Res. & Higher Edu., Prof., 高等教育機能開発総合センター, 教授 (90153212)
KAWAHATSU Kiyonori  Hokkaido Univ. Ctr of Res. & Higher Edu, Prof., 高等教育機能開発総合センター, 教授 (80026822)
Project Period (FY) 2004 – 2005
Project Status Completed (Fiscal Year 2005)
Budget Amount *help
¥15,200,000 (Direct Cost: ¥15,200,000)
Fiscal Year 2005: ¥4,100,000 (Direct Cost: ¥4,100,000)
Fiscal Year 2004: ¥11,100,000 (Direct Cost: ¥11,100,000)
KeywordsLife-style related disease / Primary prevention / Physical activity / Nutrition / Cholesterol / Obesity / Randomized controlled trial / Health volunteer / 運動指導 / 栄養指導 / 健康教育 / 無作為化介入研究 / n-3多価不飽和脂肪酸 / 食物繊維 / 歩行運動
Research Abstract

The randomized controlled primary prevention study to introduce increased physical activity and therapeutic life-style changes was carried out to reduce risk profile for cardiovascular disease and health promotion to asymptomatic habitants, male and female with menopause, aged 40 to 69 years old. A total of 316 habitants were recruited with informed consent, and allocated into three groups consisting control (A: 105) and interventional groups (B=exercise; 106, C=exercise with diet; 105). As a therapeutic life-style change, increased physical activity of 150 minutes brisk walking per week was recommended to B and C groups. In addition, nutritional instruction consisting of optimal energy intake for ideal body weight, increased intake of n-3 ploy-unsaturated fatty acid up to 2.9g a day and additional increase of dietary fiber by 2.0g more than ever were recommended to C group. Brisk walking of all participants was monitored by pedometer which enables to record at least more than 10 minutes continuous brisk walking. News letters and lectures on therapeutic life-style changes were provided to the interventional groups every month. After 1 year, risk profile was re-evaluated, resulting reduction of BMI, serum concentration of triglyceride and increased HDL-cholesterol levels in all groups. Physical activity was significantly increased in exercise groups (B & C). The interventional study with health education for normal population induced increased physical activity in the interventional groups and ameliorated lipids risk profile in all groups.

Report

(3 results)
  • 2005 Annual Research Report   Final Research Report Summary
  • 2004 Annual Research Report
  • Research Products

    (17 results)

All 2006 2005 2004

All Journal Article (16 results) Book (1 results)

  • [Journal Article] メタボリック・シンドローム集族因子の単一指標化2006

    • Author(s)
      小林玄, 河口明人
    • Journal Title

      北海道大学大学院教育学研究科紀要 98

      Pages: 251-261

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 北海道大学大学院教育学研究科2006

    • Author(s)
      河口明人
    • Journal Title

      ヘルスケアネットワークの形成に関する研究 6

      Pages: 49-61

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Simplification to Evaluate Metabolic Syndrome in Sapporo Life-style Study2006

    • Author(s)
      Gen Kobayashi, Akito Kawaguchi.
    • Journal Title

      Bulletin of Graduate School of Education, Hokkaido University 98

      Pages: 251-261

    • NAID

      120000956933

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Research for formation of Health Care Network2006

    • Author(s)
      Akito Kawaguchi
    • Journal Title

      Research for Network to support Development & Learning 6

      Pages: 49-61

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 札幌住民におけるメタボリック・シンドロームの分布2005

    • Author(s)
      小林玄ら
    • Journal Title

      日本公衆衛生雑誌 52

      Pages: 597-597

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 生活習慣病予防無作為化介入試験における糖-脂質代謝相関2005

    • Author(s)
      安江千歳ら
    • Journal Title

      日本公衆衛生雑誌 52

      Pages: 589-589

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] メタボリック・シンドロームにおける体組成と基礎代謝量2005

    • Author(s)
      加藤華奈子ら
    • Journal Title

      日本公衆衛生雑誌 52

      Pages: 597-597

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Metabolic Syndromeにおける副交感神経活動2005

    • Author(s)
      小林玄ら
    • Journal Title

      体力科学 54

      Pages: 488-488

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Distribution of Metabolic Syndrome in Sapporo Life-style Study2005

    • Author(s)
      Gen Kobayashi, Akito Kawaguchi et al.
    • Journal Title

      Jpn J Public Health 52

      Pages: 597-597

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Glucose-lipid Correlation in Prevention study for Lifestyle-related Disease2005

    • Author(s)
      Chitose Yasue, Akito Kawagcuhi et al.
    • Journal Title

      Jpn J Public Health 52

      Pages: 589-589

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Body composition and Basal Metabolic Rate in Metabolic Syndrome2005

    • Author(s)
      Kanako Kato, Akito Kawaguchi et al.
    • Journal Title

      Jpn J Public Health 52

      Pages: 597-597

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Parasympathetic nerve activity in Metabolic Syndrome2005

    • Author(s)
      Gen Kobayashi, Ryota Matsuura, Akito Kawaguchi.
    • Journal Title

      Jpn J Pysical fitness & Soprts medicine 54

      Pages: 488-488

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 札幌住民におけるメタボリック・シンドロームの分布2005

    • Author(s)
      小林玄
    • Journal Title

      日本公衆衛生雑誌 52

      Pages: 597-597

    • Related Report
      2005 Annual Research Report
  • [Journal Article] メタボリック・シンドロームにおける体組成と基礎代謝量2005

    • Author(s)
      加藤華奈子
    • Journal Title

      日本公衆衛生雑誌 52

      Pages: 597-597

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 生活習慣病予防無作為化介入試験における糖-脂質代謝相関2005

    • Author(s)
      安江千歳
    • Journal Title

      日本公衆衛生雑誌 52

      Pages: 589-589

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Metabolic Syndromeにおける副交感神経活動2005

    • Author(s)
      小林玄
    • Journal Title

      体力科学 54

      Pages: 488-488

    • Related Report
      2005 Annual Research Report
  • [Book] 内分泌・糖尿病科:「Metabolic Syndromeの系譜と臨床病態」2004

    • Author(s)
      河口明人
    • Total Pages
      7
    • Publisher
      科学評論社
    • Related Report
      2004 Annual Research Report

URL: 

Published: 2004-04-01   Modified: 2016-04-21  

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