• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Longevity and lifestyle

Research Project

Project/Area Number 16300220
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied health science
Research InstitutionGifu University

Principal Investigator

MORITA Hiroyuki  Gifu University, Graduate School of Medicine, Associate Professor (90252147)

Co-Investigator(Kenkyū-buntansha) ISHIZUKA Tatsuo  Gifu University, Graduate School of Medicine, Professor (20108070)
UNO Yoshihiro  Gifu University, Graduate School of Medicine, Associate Professor (70293553)
谷本 真由実  岐阜大学, 医学部, 助手 (10372517)
梅本 敬夫  岐阜大学, 大学院・医学研究科, 助教授 (40223614)
Project Period (FY) 2004 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥15,320,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥420,000)
Fiscal Year 2007: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2006: ¥1,900,000 (Direct Cost: ¥1,900,000)
Fiscal Year 2005: ¥4,000,000 (Direct Cost: ¥4,000,000)
Fiscal Year 2004: ¥7,600,000 (Direct Cost: ¥7,600,000)
Keywordssurvey of food / survey of exercise / adiponectin / metabolic syndrome / software for nutritional analysis / diet fiber / blood pressure monitorine / unsaturated fatty acids / DHEA-S / 長寿 / 食事解析 / 栄養調査 / 栄養解析ソフトウェア / 高齢者 / 栄養解析ソフトウエア開発 / ソフトウエア開発
Research Abstract

1. Invention of software for analysis of daily meal
We have invented software for analysis of nutrients in daily meal from photographs taken by a digital camera. Plenty of nutrients and energy are automatically calculated and summed up when a dish is painted over the photograph on the software.
2. Effect of a fiber-rich liquid diet to metabolic syndrome
We performed a randomized control study on an effect of diet fiber on metabolic syndrome. Twenty five patients with metabolic syndrome were divided randomly into two groups (an ordinary liquid group and fiber-rich liquid group) and had taken either of the liquid for six months. Endpoints were body weight, waist circumference, serum lipids, 75gOGTT, etc. We are analyzing the results.
3.Beneficial effects of a home health care system
We have prospectively investigated beneficial effects of a home health care system which is composed by an automatic sphygmomanometer and ECG with data telecommunication. The blood pressure in the user was lower than that in the non-user. No difference between the two groups was found in BMI, serum lipids and glucose tolerance.
4. Lifestyle between long-lived and short-lived areas
A cross-sectional study on lifestyle between long-lived and short-lived areas in Gifu Prefecture was performed by medical checkup, photographs of the food and questionnaires. In the long-lived area, blood pressure, ability of exercise, plasma adiponectin concentrations and intake of n-3/n-6 ratio of unsaturated fatty acids were higher than the short-lived one.

Report

(5 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • Research Products

    (45 results)

All 2008 2007 2006 2005 2004 Other

All Journal Article (32 results) (of which Peer Reviewed: 12 results) Presentation (13 results)

  • [Journal Article] DHEA-sulfate concentration in Men from a Japanese longevity district2008

    • Author(s)
      Matsumoto M, Ishizuka T, Morita H, Uno Y, et. al.
    • Journal Title

      Geriatr Gerontol Int (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Effect of fasting on PPARγ and AMPK activity in adipocytes2008

    • Author(s)
      Kajita K, Uno Y, Morita H, Ishizuka T, et. al.
    • Journal Title

      Diabetes Res Clin Pract (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Platelet aggregation in obese and diabetic subjects: association with leptin level2007

    • Author(s)
      Sugiyama C, Morita H, Uno Y, IshizukaT, et. al.
    • Journal Title

      Platelets 18

      Pages: 128-134

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Effect of dehydroepiandrosterone on insulin sensitivity in Otsuka Long-Evans Tokushima-fatty rats2007

    • Author(s)
      Ishizuka T, Morita H, Uno Y, et. al.
    • Journal Title

      Acta Diabetol 44

      Pages: 219-226

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Platelet aggregation in obese and diabetic subjects : association with leptin level2007

    • Author(s)
      Sugiyama, C, Morita, H, Uno, Y, Ishizuka, T, et. al.
    • Journal Title

      Platelets 18

      Pages: 128-134

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Effect of dehydroepi-androsterone on insulin sensitivity in Otsuka Long-Evans Tokushima-fatty rats2007

    • Author(s)
      Ishizuka, T, Morita, H, Uno, Y, et. al.
    • Journal Title

      Acta Diabetol 44

      Pages: 219-226

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Platelet aggregation in obese and diabetic subjects: association with leptin level.2007

    • Author(s)
      Sugiyama C, et. al.
    • Journal Title

      Platelets 18

      Pages: 128-134

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 在宅健康管理システム利用による生活習慣病関運指標への効果-健康診断での非利用者との比較研究-2007

    • Author(s)
      森田浩之、他
    • Journal Title

      日本遠隔医療学会雑誌 3

      Pages: 229-230

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Physiologic roles of 11β-hydroxydehydrogenase type 2 in kidney2006

    • Author(s)
      Isomura Y, Morita H, et. al.
    • Journal Title

      Metabolism 55

      Pages: 1352-1357

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Physiologic roles of 11B-hydroxydehydrogenase type 2 in kidney2006

    • Author(s)
      Isomura, Y, Morita, H, et. al.
    • Journal Title

      Metabolism 55

      Pages: 1352-1357

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Physiologic roles of 11β-hydroxydehydrogenase type 2 in kidney2006

    • Author(s)
      Isomura Y, et al.
    • Journal Title

      Metabolism 55・10

      Pages: 1352-1357

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 医学生による訪問看護体験実習の評価2006

    • Author(s)
      森田浩之, 他
    • Journal Title

      医学教育 37・5

      Pages: 311-315

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 両側に副腎皮質腺腫がみられた原発性アルドステロン症の1例-右アルドステロン産生腺腫と左非機能性腺腫-2006

    • Author(s)
      森田浩之, 他
    • Journal Title

      日本内分泌学会雑誌 82・補

      Pages: 61-63

    • NAID

      10018812418

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 医学生の訪問看護体験実習の評価2006

    • Author(s)
      森田浩之, 宇野嘉弘, 他
    • Journal Title

      医学教育 37・4(印刷中)

    • NAID

      10019267173

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Paraneoplastic neurologic syndrome and autoimmune Addison disease in a patient with thymoma2005

    • Author(s)
      Morita H, Ishizuka T, et. al.
    • Journal Title

      Am J Med Sci 329

      Pages: 48-51

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Correlation between left ventricular mass and urinary sodium excretion in specific genotype of CYP11B22005

    • Author(s)
      Isaji M, Morita H, et. al.
    • Journal Title

      J Hypertens 23

      Pages: 1149-1157

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Association of Lys173Arg polymorphism with CYP11B2 expression in normal adrenal glands and aldosterone-producing adenomas2005

    • Author(s)
      Tanahashi H, Morita H, et. al.
    • Journal Title

      J Clin Endocrinol Metab 90

      Pages: 6226-6231

    • NAID

      110004462211

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Paraneoplastic neurologic syndrome and autoimmune Addison disease in a patient with thymoma2005

    • Author(s)
      Morita, H, Ishizuka, T, et. al.
    • Journal Title

      Am J Med Sci 329

      Pages: 48-51

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Correlation between left ventricular mass and urinary sodium excretion in specific genotype of CYP11B22005

    • Author(s)
      Isaji, M, Morita, H, et. al.
    • Journal Title

      J Hypertens 23

      Pages: 1149-1157

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Association of Lys173Arg polymorphism with CYP11B2 expression in normal adrenal glands and aldosterone-producing adenomas2005

    • Author(s)
      Tanahashi, H, Morita, H, et. al.
    • Journal Title

      J Olin Endocrinol Metab 90

      Pages: 6226-6231

    • NAID

      110004462211

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Paraneoplastic neurologic syndrome and autoimmune Addison disease in a patient with thymoma2005

    • Author(s)
      Morita H, Hirota T, et al.
    • Journal Title

      Am J Med Sci 329・1

      Pages: 48-51

    • Related Report
      2005 Annual Research Report 2004 Annual Research Report
  • [Journal Article] Plasma cortisol and cortisone concentrations in normal subjects and patients with adrenocortical disorders2004

    • Author(s)
      Morita H, Ishizuka T, et. al.
    • Journal Title

      Metabolism 53

      Pages: 89-94

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Protein kinase C(PKC)β modulates rerine phaophorylation of insulin receptor substrate-1(IRS-1)-effect of overexpressin of PKCβ on insulin signal transduction2004

    • Author(s)
      Ishizuka T, Morita H, Uno Y, et. al.
    • Journal Title

      Endocr Res 30

      Pages: 287-299

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Plasma cortisol and cortisone concentrations in normal subjects and patients with adrenocortical disorders2004

    • Author(s)
      Morita, H, Ishizuka, T, et. al.
    • Journal Title

      Metabolism 53

      Pages: 89-94

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Protein kinase C (PKC) B modulates rerine phaophorylation of insulin receptor substrate-1 (IRS-1) -effect of overexpressin of PKCB on insulin signal transduction2004

    • Author(s)
      Ishizuka, T, Morita, H, Uno, Y, et. al.
    • Journal Title

      Endocr Res 30

      Pages: 287-299

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] γアミノ酪酸富化胚芽米長期摂取による生活習慣病関連指標への効果2004

    • Author(s)
      森田浩之, 宇野嘉弘, 梅本敬夫, 他
    • Journal Title

      日本老年医学会雑誌 41・2

      Pages: 211-216

    • NAID

      10013289806

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 大腸潰瘍を伴う偽性腸閉塞を発症した慢性甲状腺炎合併ミトコンドリア糖尿病2004

    • Author(s)
      森田浩之, 山田浩司, 宗友厚, 他
    • Journal Title

      日本内分泌学会雑誌 80・増

      Pages: 105-108

    • NAID

      10013292572

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Graves病の治療中に発症したHTLV-1ぶどう膜炎の1例2004

    • Author(s)
      森田浩之, 松本雅美, 宇野嘉弘, 他
    • Journal Title

      内科専門医会雑誌 16・4

      Pages: 651-654

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 地域在宅高齢者における栄養アセスメント指標および栄養摂取の現状2004

    • Author(s)
      園木浩文, 鳩宿篤子, 森田浩之, 他
    • Journal Title

      栄養評価と治療 21・6

      Pages: 539-543

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 地域在宅高齢者における栄養アセスメント指標と分岐鎖アミノ酸との関係について2004

    • Author(s)
      鳩宿篤子, 園木浩文, 森田浩之, 他
    • Journal Title

      栄養評価と治療 21・6

      Pages: 545-548

    • Related Report
      2004 Annual Research Report
  • [Journal Article] DHEA-sulfates concentration in Men from a Japanese longevity district

    • Author(s)
      Matsumoto, M, Ishizuka, T, Morita, H, Uno, Y, et. al.
    • Journal Title

      Geriatr Gerontol Int (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Effect of fasting on PPARy and AMPK activity in adipocytes

    • Author(s)
      Kajita, K, Uno, Y, Morita, H, Ishizuka, T, et. al.
    • Journal Title

      Diabetes Res Olin Pract (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 在宅健康管理システム利用による生活習慣病関連指標への効果-健康診断での非利用者との比較研究-.2007

    • Author(s)
      森田浩之、他
    • Organizer
      平成19年度日本遠隔医療学会学術大会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2007-10-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] Association of longevity factors with blood pressure, ability of exercise or glucose tolerance2006

    • Author(s)
      Ishizuka, T, Morita, H, Uno, Y, et. al.
    • Organizer
      66th Scientific Sessions of American Diabetes Associations
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2006-06-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Association between platelet aggregation and obesity index2006

    • Author(s)
      Sugiyama, C, Morita, H, Uno, Y, Ishizuka T, et. al.
    • Organizer
      66th Scientific Sessions of American Diabetes Associations
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2006-06-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Association of evity factors with blood pressure, ability of exercise or glucose tolerance2006

    • Author(s)
      Ishizuka, T, Matsumoto, M, Morita, H, Uno, Y, et. al.
    • Organizer
      66th Scientific Sessions of American long Diabetes Associations
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2006-06-09
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Association of longevity factors with blood pressure, ability of exercise or glucose tolerance?2006

    • Author(s)
      Ishizuka T, Matsumoto M, Morita H, Uno Y, et. al.
    • Organizer
      66th Scientific Sessions of American Diabetes Associations
    • Place of Presentation
      Washington DC, USA
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effect of dehydroepiandrosterone (DHEA) on insulin resistance and DHEA-sulfate concentration in male adults of Japanese longevity district2005

    • Author(s)
      Ishizuka, T, Morita, H, Uno, Y, et. al.
    • Organizer
      41st Annual Meeting of the European Association for the Study of Diabetes
    • Place of Presentation
      Athens, Greece
    • Year and Date
      2005-09-13
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Platelet aggregation in obese and diabetic subjects-association with leptin Level2005

    • Author(s)
      Sugiyama, C, Morita, H, Uno, Y, T, Ishizuka, T, et. al.
    • Organizer
      65th Scientific Sessions of American Diabetes Associations
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2005-06-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Relationship between depressive scale and lifestyle in new outpatients2005

    • Author(s)
      Morita, H, Uno, Y, Ishizuka, T, et. al.
    • Organizer
      WONCA Asia Pacific Regional Conference 2005
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2005-05-28
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Relationship between depressive scale and lifestyle in new outpatients2005

    • Author(s)
      Morita H, Uno Y, Ishizuka T, et. al.
    • Organizer
      WONCA Asia Pacific Regional Conference
    • Place of Presentation
      Kyoto, Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Dehydroepiandrosterone-induced improvement of insulin resistance in rat adipocytes and its clinical significance in male adults2005

    • Author(s)
      Ishizuka T, Morita H, Uno Y, et. al.
    • Organizer
      65th Scientific Sessions of American Diabetes Associations
    • Place of Presentation
      San Diego, USA
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Platelet aggregation in obese and diabetic subjects-association with leptin level2005

    • Author(s)
      Sugiyama C, Morita H, Uno Y, Ishizuka T, et. al.
    • Organizer
      65th Scientific Sessions of American Diabetes Associations
    • Place of Presentation
      San Diego, USA
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effect of dehydroepiandrosterone(DHEA)on insulin resistance and DHEA-sulfate concentration in male adults of Japanese longevity district2005

    • Author(s)
      Ishizuka T, Morita H, Uno Y, et. al.
    • Organizer
      41st Annual Meeting of the European Association for the Study of Diabetes
    • Place of Presentation
      Athens, Greece
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] The Association of dehydroepiandrosterone with insulin sensitivity of male adults and longevity in Japan2004

    • Author(s)
      Ishizuka T, Morita H, Uno Y, et. al.
    • Organizer
      64th Scientific Sessions of American Diabetes Associations
    • Place of Presentation
      Orlando, USA
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary

URL: 

Published: 2004-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi