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Evaluation of the difficulty in deglutition and the development of thickening agents for dysphagia

Research Project

Project/Area Number 16300237
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Eating habits, studies on eating habits
Research InstitutionOSAKA CITY UNIVERSITY

Principal Investigator

NISHINARI Katsuyoshi  Osaka City University, Graduate School of Human Life Science, Professor, 大学院生活科学研究科, 教授 (10254426)

Co-Investigator(Kenkyū-buntansha) TACHIMURA Takashi  Osaka University, Graduate School of Dentistry, Division of Functional Oral Neuroscience, Associate professor, 大学院・歯学研究科, 助教授 (60188266)
YOSHIMURA Miki  University of Hyogo, School of Human Science and Environment, Associate Professor, 環境人間学部, 助教授 (90240358)
Project Period (FY) 2004 – 2005
Project Status Completed (Fiscal Year 2005)
Budget Amount *help
¥8,900,000 (Direct Cost: ¥8,900,000)
Fiscal Year 2005: ¥2,700,000 (Direct Cost: ¥2,700,000)
Fiscal Year 2004: ¥6,200,000 (Direct Cost: ¥6,200,000)
Keywordselectromyography / palatoglossus muscle / levator veli palatini muscle / optimum volume / oral phase / pharyngeal phase / Xanthan gum / Minced food / 口腔相 / 咽頭相 / ビデオ嚥下造影検査法 / 降伏応力 / のどごし
Research Abstract

In the present work, rheological properties of various polysaccharides and commercially available thickening agents used in hospitals and homes have been studied. It was found that the mixtures of xanthan-xyloglucan and xyloglucan-gellan form a gel although each individual polysaccharide does not form a gel in dilute regime. Effects of the quantity of drinks, viscosity and yield stress of the mixture of contrast medium and thickening agent on the swallowing process was examined by videofluorography, and it was found that silent aspiration is induced when the viscosity is too low, and that the too high yield stress of the drinks tend to make remain the drinks on the vallecula.
It is important to electromyographically clarify the aspect of regulation of the levator veli palatini and the palatoglossus muscles during transition from the oral to the pharyngeal phases during swallowing. When water was used as tested food, activity of both muscles changed in relation to swallowing volume in a … More range specific to each subject, which was determined on the basis of optimum swallowing volume individually. When liquid with relatively greater viscosity was used as a test food, swallowing volume was statistically changed in relation to change in viscosity. There was significant correlation between viscosity and swallowing volume. When viscosity of test food was changed, both muscle activities were significantly changed in relation to both viscosity and swallowing volume. Levator veli palatini muscle activity was correlated with changes in viscosity and swallowing volume with multiple correlation coefficients ranged from 0.795 to 0.869. However, the multiple correlation coefficients for palatoglossus muscle activity were ranged from 0.562 to 0.745. Therefore, it can be supposed that activity of the palatoglossus muscle could be regulated with other factors as well as two factors tested here.
The relationship between the rheological properties of xanthan gum(0.6, 1.2, 2.0%) with different intrinsic viscosities(15.6, 16.0, 16.5, 20.0 dl/g) and the palatabilities of the minced carrots with the xanthan gum was examined by steady shear viscosity, dynamic viscoelasticity measurements, and sensory evaluation. Adding xanthan gum reduced the number and the time for chewing of minced carrots. The aged panel judged that minced carrots with xanthan gum (intrinsic viscosity : 15.6dl/g, concentration : 0.6%) were of better mouthfeel and easy to swallow than minced carrots without xanthan gum and cut carrots without xanthan gum. The age panel with full dentures judged that cut carrots were best to masticate, because minced carrots were too small to masticate. Less

Report

(3 results)
  • 2005 Annual Research Report   Final Research Report Summary
  • 2004 Annual Research Report
  • Research Products

    (49 results)

All 2006 2005 2004 Other

All Journal Article (47 results) Book (2 results)

  • [Journal Article] Change in levator veli palatini muscle activity in relation to swallowing volume during the transition from the oral phase to pharyngeal phase.2006

    • Author(s)
      T.Tachimura, K.Okuno, M.Ojima, K.Nohara:
    • Journal Title

      Dysphagia (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Levator veli palatini muscle fatigue during phonation in speakers with cleft palate with borderline velopharyngeal incompetence.2006

    • Author(s)
      K.Nohara, T.Tachimura, T.Wada
    • Journal Title

      Cleft Palate-Craniofacial Journal 43・1

      Pages: 103-107

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] Anomalous rheological behaviour of gum Arabic solutions2006

    • Author(s)
      S.Tanaka, Y.Fang, K.Nishinari
    • Journal Title

      Food & Food Ingredients Journal of Japan 211・3

      Pages: 216-221

    • NAID

      40007267529

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Synergistic interaction of xyloglucan and xanthan investigated by rheology, differential scanning calorimetry, and NMR2006

    • Author(s)
      B.S.Kim, M.Takemasa, K.Nishinari
    • Journal Title

      Biomacromolecules 7・4

      Pages: 1223-1230

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Anomalous rheological behaviour of gum Arabic solutions2006

    • Author(s)
      S.Tanaka, Y.Fang, K.Nishinari
    • Journal Title

      Food & Food Ingredients Journal of Japan 211(3)

      Pages: 216-221

    • NAID

      40007267529

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Synergistic interaction of xyloglucan and xanthan investigated by rheology, differential scanning calorimetry, and NMR2006

    • Author(s)
      B.S.Kim, M.Takemasa, K.Nishinari
    • Journal Title

      Biomacromolecules 7(4)

      Pages: 1223-1230

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Change in levator veli palatini muscle activity in relation to swallowing volume during the transition from the oral phase to pharyngeal phase.2006

    • Author(s)
      T.Tachimura, K.Okuno, M.Ojima, K.Nohara
    • Journal Title

      Dysphagia 21(in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Change in levator veli palatini muscle activity in relation to swallowing volume during the transition from the oral phase to pharyngeal phase.2006

    • Author(s)
      T.Tachimura, K.Okuno, M.Ojima, K.Nohara
    • Journal Title

      Dysphagia (in press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Change in palatoglossus muscle activity in relation to swallowing volume during the transition from the oral phase to pharyngeal phase2005

    • Author(s)
      T.Tachimura, M.Ojima, K.Nohara.et al.
    • Journal Title

      Dysphagia 20・1

      Pages: 32-39

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Velar ascent and morphological factors in velopharyngeal function in cleft palate patients and noncleft controls : a cephalometric study2005

    • Author(s)
      K.Satoh, T.Wada, T.Tachimura, J.Fukuda
    • Journal Title

      International Journal of Oral & Maxillofacial Surgery 34・2

      Pages: 122-126

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] 固有粘度の異なるキサンタンガムの物性とニンジンのきざみ食の咀嚼性2005

    • Author(s)
      吉村美紀, 桑野稔子, 船見孝博, 西成勝静
    • Journal Title

      日本咀嚼学会雑誌 15・2

      Pages: 48-57

    • NAID

      10016929383

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Effects of molar mass on the coil to helix transition of sodium-type gellan gums in aqueous solutions2005

    • Author(s)
      E.Ogawa, R.Takahashi, H.Yajima, K.Nishinari
    • Journal Title

      Food Hydrocolloids 20・2-3

      Pages: 378-385

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 食べ物および食べる過程とレオロジー2005

    • Author(s)
      西成勝好
    • Journal Title

      日本バイオレオロジー学会誌(B&R) 9・1

      Pages: 3-15

    • NAID

      130001932280

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 食品の物性におけるハイドロゲルに関する研究2005

    • Author(s)
      西成勝好
    • Journal Title

      日本食品科学工学会誌 52・9

      Pages: 385-390

    • NAID

      130000052411

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 食感の創出素材-テクスチャーモディファイヤーの現状と課題2005

    • Author(s)
      西成勝好
    • Journal Title

      日本調理科学会誌 38・5

      Pages: 397-403

    • NAID

      110001877004

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] 日本語テクスチャー用語の収集2005

    • Author(s)
      早川文代, 井奥加奈, 阿久澤さゆり, 齋藤昌義, 西成勝好, 山野善正, 神山かおる
    • Journal Title

      日本食品科学工学会誌 52・8

      Pages: 337-346

    • NAID

      10019043861

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] おいしさを創るハイドロコイド2005

    • Author(s)
      西成勝好, 船見孝博
    • Journal Title

      令凍2005年5月号 80・931

      Pages: 7-14

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 食品のテクスチャー評価と改質技術2005

    • Author(s)
      西成勝好, 平島円
    • Journal Title

      ジャパンフードサイエンス 44・8

      Pages: 19-25

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Change in Palatoglossus muscle activity in relation to swallowing volume during the transition from the oral phase to pharyngeal phase.2005

    • Author(s)
      T.Tachimura, M.Ojima, K.Nohara, T.Wada
    • Journal Title

      Dysphagia 20(1)

      Pages: 32-39

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Levator veli palatini muscle fatigue during phonation in speakers with cleft palate with borderline velopharyngeal incompetence.2005

    • Author(s)
      K.Nohara, T.Tachimura, T.Wada
    • Journal Title

      Cleft Palate-Craniofacial Journal 43(1)

      Pages: 103-107

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Velar ascent and morphological factors in velopharyngeal function in cleft palate patients and noncleft controls : a cephalometric study2005

    • Author(s)
      K.Satoh, T.Wada, T.Tachimura, J.Fukuda
    • Journal Title

      International Journal of Oral & Maxillofacial Surgery 34(2)

      Pages: 122-126

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rheological Properties of Xanthan Gum of Different Intrinsic Viscosity and Mastication of the Minced Carrots2005

    • Author(s)
      M.Yoshimura, T.Kuwano, T.Funami, K.Nishinari
    • Journal Title

      Japanese Society for Mastication Science and Health Promotion 15(2)

      Pages: 48-57

    • NAID

      10016929383

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Effects of molar mass on the coil to helix transition of sodium-type gellan gums in aqueous solutions2005

    • Author(s)
      E.Ogawa, R.Takahashi, H.Yajima, K.Nishinari
    • Journal Title

      Food Hydrocolloids 20(2-3)

      Pages: 378-385

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rheology in foods and eating process2005

    • Author(s)
      K.Nishinari
    • Journal Title

      Japanese Journal of Biorheology 9(1)

      Pages: 3-15

    • NAID

      130001932280

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Study on hydrogels in food physics2005

    • Author(s)
      K.Nishinari
    • Journal Title

      Nippon Shokuhin Kagaku Kogaku Kaishi 52(9)

      Pages: 385-390

    • NAID

      130000052411

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] New texture modifiers- Present situation and future problems2005

    • Author(s)
      K.Nishinari
    • Journal Title

      Japanese Journal of Cookery Science 38(5)

      Pages: 397-403

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Collection of Japanese texture terms(Studies on Japanese texture expressions Part1.)2005

    • Author(s)
      F.Hayakawa, K.Ioku, S.Akuzawa, M.Saito, K.Nishinari, Y.Yamano, K.Kohyama
    • Journal Title

      Nippon Shokuhin Kagaku Kogaku Kaishi 52(8)

      Pages: 337-346

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Hydrocolloids for creating palatable foods2005

    • Author(s)
      K.Nishinari, T.Funami
    • Journal Title

      Reito 80(931)

      Pages: 7-14

    • NAID

      10015666427

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Evaluation and control of food texture2005

    • Author(s)
      K.Nishinari, M.Hirashima
    • Journal Title

      Japan Food Science 44(8)

      Pages: 19-25

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 固有粘度の異なるキサンタンガムの物性とニンジンのきざみ食の咀嚼性2005

    • Author(s)
      吉村美紀, 桑野稔子, 船見孝博, 西成勝好
    • Journal Title

      日本咀嚼学会雑誌 15・2

      Pages: 48-57

    • NAID

      10016929383

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Change in palatoglossus muscle activity in relation to swallowing volume during the transition from the oral phase to pharyngeal phase2005

    • Author(s)
      Tachimura T, Ojima M, Nohara K, et al.
    • Journal Title

      Dysphagia (in press)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] キサンタンガムを添加したきざみ食の嗜好特性について2005

    • Author(s)
      吉村美紀, 桑野稔子, 盛崎利恵, 西成勝好
    • Journal Title

      日本咀嚼学会雑誌 14・2

      Pages: 50-61

    • NAID

      10014493663

    • Related Report
      2004 Annual Research Report
  • [Journal Article] キサンタンガムを添加したきざみ食の嗜好特性について2004

    • Author(s)
      吉村美紀, 桑野稔子, 盛綺利恵, 西成勝好
    • Journal Title

      日本咀嚼学会雑誌 14・2

      Pages: 50-61

    • NAID

      10014493663

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] トロミ調整食品『トロメイク』で粘性を調整したバリウム製剤の物性評価2004

    • Author(s)
      外山義雄, 竹端彩, 高見正雄, 村尾周久, 金保叔, 西成勝好, 清水隆雄, 藤岡誠司, 音無弘子
    • Journal Title

      日本摂食嚥下リハビリテーション学会誌 8・2

      Pages: 213-213

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 簡易粘度計の試作検討とトロミ評価への適用2004

    • Author(s)
      外出義雄, 竹端彩, 高見正雄, 村尾周久, 金保叔, 西成勝好, 井元俊之
    • Journal Title

      日本摂食嚥下リハビリテーション学会誌 8・2

      Pages: 213-213

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rheology, food texture and mastication2004

    • Author(s)
      K.Nishinari
    • Journal Title

      J. Texture Studies 35

      Pages: 113-124

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rheology, food texture and mastication2004

    • Author(s)
      K.Nishinari
    • Journal Title

      J.Texture Studies 35

      Pages: 113-124

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rheological characterization of contrast medium containing barium ; viscosity of the contrast medium was controlled by a thickening agent "toromake"2004

    • Author(s)
      Y.Toyama, A.Takeba, M.Takami, K.Murao, B.S.Kim, K.Nishinari, T.Shimizu, S.Hujioka, H.Otonashi
    • Journal Title

      The Japanese Society of Dysphagia Rehabilitation 8(2)

      Pages: 213-213

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A simple and rapid measurement of the viscosity and its application for thickening agents2004

    • Author(s)
      Y.Toyama, A.Takeba, M.Takami, K.Murao, B.S.Kim, K.Nishinari, T.Imoto
    • Journal Title

      The Japanese Society of Dysphagia Rehabilitation 8(2)

      Pages: 213-213

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rheological Properties and Sensory Evaluation of the Minced Foods with Xanthan Gum2004

    • Author(s)
      M.Yoshimura, T.Kuwano, R.Morisaki, K.Nishinari
    • Journal Title

      Japanese Society for Mastication Science and Health Promotion 14(2)

      Pages: 50-61

    • NAID

      10014493663

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 口蓋裂術後鼻咽腔閉鎖不全症例における発音時の口蓋帆挙筋の疲労に関する研究-健常者との相違-2004

    • Author(s)
      野原幹司, 舘村 卓, 和田 健, 他
    • Journal Title

      日本口腔外科学会誌 50・8

      Pages: 455-460

    • NAID

      10018619346

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 小型圧力センサ-を用いた舌接触補肋床の作製法2004

    • Author(s)
      野原幹司, 舘村 卓, 和田 健, 他
    • Journal Title

      音声言語医学 45・3

      Pages: 192-195

    • Related Report
      2004 Annual Research Report
  • [Journal Article] トロミ調整食品『トロメイク』で粘性を調整したバリウム製剤の物性評価2004

    • Author(s)
      外山義雄, 竹端彩, 高見正雄, 村尾周久, 金保叔, 西成勝好, 清水隆雄, 藤岡誠司, 音無弘子
    • Journal Title

      日本摂食・嚥下リハビリテーション学会雑誌 8・2

      Pages: 213-213

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 簡易粘度計の試作検討とトロミ評価への適用2004

    • Author(s)
      外山義雄, 竹端彩, 高見正雄, 村尾周久, 金保叔, 西成勝好, 井元俊之
    • Journal Title

      日本摂食・嚥下リハビリテーション学会雑誌 8・2

      Pages: 213-213

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Rheological and related study of gelation of xyloglucan in the presence of small molecules and other polysaccharides

    • Author(s)
      K.Nishinari, B.S.Kim, Y.Fang, Y.Nitta, M.Takemasa
    • Journal Title

      Cellulose (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rheological and related study of gelation of xyloglucan in the presence of small molecules and other polysaccharides

    • Author(s)
      K.Nishinari, B.S.Kim, Y.Fang, Y.Nitta, M.Takemasa
    • Journal Title

      Cellulose (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rheological and related study of gelation of xyloglucan in the presence of small molecules and other polysaccharides

    • Author(s)
      K.Nishinari, B.S.Kim, Y.Fang, Y.Nitta, M.Takemasa
    • Journal Title

      Cellulose (in press)

    • Related Report
      2005 Annual Research Report
  • [Book] 食感創造ハンドブック2005

    • Author(s)
      西成勝好, 大越ひろ, 神山かおる, 山本隆編
    • Publisher
      サイエンスフォーラム
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Book] Sol-gel transition in polysaccharides In "Comprehensive Handbook of Calorimetry & Thermal Analysis" (M. Sorai Ed.)2004

    • Author(s)
      K.Nishinari
    • Total Pages
      3
    • Publisher
      John Wiley & Sons, Ltd.
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary

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Published: 2004-04-01   Modified: 2016-04-21  

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