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Development of SNP catalog toward to disease mapping by sequence determination of the HLA haplotypes

Research Project

Project/Area Number 16310136
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field 基礎ゲノム科学
Research InstitutionTokai University

Principal Investigator

SHIINA Takashi  Tokai University, School of Medicine, Lecturer (00317744)

Co-Investigator(Kenkyū-buntansha) TOKUNAGA Katsushi  Tokyo University, School of Medicine, Professor (40163977)
INOKO Hidetoshi  Tokai University, School of Medicine, Professor (10101932)
ANDO Asako  Tokai University, School of Medicine, Lecturer (40101935)
Project Period (FY) 2004 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥16,640,000 (Direct Cost: ¥15,500,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2007: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2006: ¥3,800,000 (Direct Cost: ¥3,800,000)
Fiscal Year 2005: ¥3,800,000 (Direct Cost: ¥3,800,000)
Fiscal Year 2004: ¥4,100,000 (Direct Cost: ¥4,100,000)
KeywordsHLA / diversity / polymorphism / sequencing / SNP / ハプロタイプ
Research Abstract

A plausible explanation for many MHC-linked diseases is lacking. Sequencing of the MHC region (coding units or full contigs) in several human and primate single haplotypes allowed an analysis of Single Nucleotide Variations (SNV) across this entire segment. We demonstrate that the MI-IC-I diversity is not limited to the antigen/TCR binding sites but spreads to surrounding segments. Corroborating data suggests that this hitchhiking diversity, otherwise eliminated by purifying selection in most other genomic sites, has perdured within the MHC perhaps because of the strong biological incentive for constant generation and maintenance of a species-specific diverse allelic repertoire. This was evidenced by the existence of a large reservoir of hvSNV, reminiscent of the fact that most of MHC diversity is de novo generated and not as the result of their trans-species inheritance as initially thought.This result finally puts the MHC in line with the bulk of population and evolutionary genetics data which firmly conclude that a narrow bottleneck has occurred at the origin of our species, -a fact inconsistent with massive flow of alleles from one species to the next as required by the trans-species postulate.Moreover, this fitness in fighting infections seems to have taken its toll on neighboring loci, as the most gene-rich and polymorphic segment around HLA-B is also where most MHC-I diseases are mapped to.Finally, this observation is not limited to the MHC class I region as it extends to the other MHC-disease associations and perhaps to the wider genome.

Report

(5 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • Research Products

    (268 results)

All 2008 2007 2006 2005 2004 Other

All Journal Article (203 results) (of which Peer Reviewed: 98 results) Presentation (63 results) Book (2 results)

  • [Journal Article] Donner killer immunoglobulin-like receptor(KIR) genotype-patient cognate KIR Igand combination and antithymocyte globulin preadministration are critical factors in outcome of HLA-C-KIR ligand-mismatched T Cell-replete unrelated bone marrow transplantation2008

    • Author(s)
      Yabe, T, Matsuo, T, Hirayasu, K, Kashiwase, K, Kawamura-Ishii, S, Tanaka, H, Ogawa, A, Takanashi, M, Satake, M, Nakajima, K, Tokunaga, K, Inoko, H, Saji, H, Ogawa, S, Juji, T, Sasazuki, T, Kodera, Y, Morishima
    • Journal Title

      Biology of Blood and Marrow Transplantation(BBMT) 14

      Pages: 75-87

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Identification of heat shock protein 70 genes HSPA2, HSPA5 and HSPA8 from the Japanese quail, Coturnix japonica2008

    • Author(s)
      Iwamoto, S, Sato, S, Hosomichi, K, Taweetungtragoon, A, Shona, T, Matsubayashi, H, Hara, H, Yoshida, Y, Kanzawa, K
    • Journal Title

      Animal Sci J 79

      Pages: 171-181

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] A BAC-based contig map of the cynomolgus macaque (Macaca fascicularis)major histocompatibility complex genomic region2007

    • Author(s)
      Watanabe A
    • Journal Title

      Genomics 89

      Pages: 402-412

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Effects of a new immunosuppressive agent,beta-SQAG9,in swine kidney transplantation2007

    • Author(s)
      Tanaka T
    • Journal Title

      Transpl Immunol 18

      Pages: 67-71

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] A third broad lineage of major histocompatibility complex(MHC)class I in teleost fish;MHC class II linkage and processed genes2007

    • Author(s)
      Dijkstra JM
    • Journal Title

      Immunogenetics 59

      Pages: 305-321

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Extended gene map reveals tripartite motif,C-type lectin,and Ig superfamily type genes within a subregion of the chicken MHC-B affecting infectious disease2007

    • Author(s)
      Shiina T
    • Journal Title

      J Immunol. 178

      Pages: 7162-7172

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Synergistic association of mitochondrial uncoupling protein(UCP)genes with schizophrenia2007

    • Author(s)
      Yasuno K
    • Journal Title

      Am J Med Genet B Neuropsychiatr Genet 144

      Pages: 250-253

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Two critical genes(HLA-DRB1 and ABCF1)in the HLA region are associated with the susceptibility to autoimmune pancreatitis2007

    • Author(s)
      Ota M
    • Journal Title

      Immunogenetics 59

      Pages: 45-52

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] One-step generation of recombineering constructs by asymmetric-end ligation and negative selection2007

    • Author(s)
      Ohtsuka M
    • Journal Title

      Anal Biochem 360

      Pages: 306-308

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Mapping of susceptibility and protective loci for acute GVHD in unrelated HLA-matched bone marrow transplantation donors and recipients using 155 microsatellite markers on chromosome 222007

    • Author(s)
      Kikuchi T
    • Journal Title

      Immunogenetics 59

      Pages: 99-108

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Genes in the HLA region indicative for head and neck squamous cell carcinoma2007

    • Author(s)
      Reinders J
    • Journal Title

      Mol Immunol 44

      Pages: 848-855

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Microsatellite markers for genome-wide association studies2007

    • Author(s)
      Bahram S
    • Journal Title

      Nature Reviews Genetics 8

      Pages: 164-164

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] High-resolution mapping for essential hypertension using microsatellite markers2007

    • Author(s)
      Yatsu K
    • Journal Title

      Hypertension 49

      Pages: 446-452

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Effects of HLA allele and killer immunoglobulin-like receptor ligand matching on clinical outcome in leukemia patients undergoing transplantation with T-cell-replete marrow from an unrelated donor2007

    • Author(s)
      Morishima Y
    • Journal Title

      Biol Blood Marrow Transplant 13

      Pages: 315-328

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Exclusion of transforming growth factor-betal as a candidate gene for myopia in the Japanese2007

    • Author(s)
      Hayashi T
    • Journal Title

      Jpn J Ophthalmol 51

      Pages: 96-99

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Alternative splicing due to an intronic SNP in HMSD generates a novel minor histocompatibility antigen2007

    • Author(s)
      Kawase T
    • Journal Title

      Blood 110

      Pages: 1055-1063

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] High-risk HLA allele mismatch combinations responsible for severe acute graft versus host disease and implication for its molecular mechanism2007

    • Author(s)
      Kawase T
    • Journal Title

      Blood 110

      Pages: 2235-2241

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] The COL1A1 gene and high myopia susceptibility in Japanese2007

    • Author(s)
      Inamori Y
    • Journal Title

      Hum Genet 122

      Pages: 151-157

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Immunological actions of Sophy β-Gllucan (β-1,3-1,6 Gulucan),currently available commercially as a health food supplement2007

    • Author(s)
      Ikewaki N
    • Journal Title

      Microbiol Immunol 51

      Pages: 861-873

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Human leukocyte antigen may predict outcome of primary recurrent spontaneous abortion treated with paternal lymphocyte alloimmunization therapy2007

    • Author(s)
      Kano T
    • Journal Title

      Am J Reprod Immunol 58

      Pages: 383-387

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Lack of association of Toll-like receptor 9 gene polymorphism with Behcet's disease in Japanese patients2007

    • Author(s)
      Ito A
    • Journal Title

      Tissue Antigens 70

      Pages: 423-426

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Association of autoimmune disease-related gene polymorphisms with chronic graft-versus-host disease2007

    • Author(s)
      Shimada M
    • Journal Title

      Br J Haematol 139

      Pages: 458-463

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Single nucleotide polymorphism detection by polymerase chain reaction-restriction fragment length polymorphism2007

    • Author(s)
      Ota M
    • Journal Title

      Nature Protoc 11

      Pages: 2857-2864

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] A single nucleotide polymorphism analysis of the LAMAA1 gene in Japanese patients with high myopia2007

    • Author(s)
      Sasaki S
    • Journal Title

      Clinical Opthalmology 1

      Pages: 289-295

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Lack of association with high myopia and the MYP2 locus in the Japanese population by high resolution analysis on chromosome 182007

    • Author(s)
      Yamane T
    • Journal Title

      Clinical Opthalmology 1

      Pages: 311-316

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Genetic analysis of craniofacial traits in the medaka2007

    • Author(s)
      Kimura T
    • Journal Title

      Genetics 177

      Pages: 2379-2388

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Decrease in CD93(C1qRp) expression in a human monocyte cell line(U937)treated with various apoptosis-inducing chemical substances2007

    • Author(s)
      Ikewaki N
    • Journal Title

      Microbiol Immunol 51

      Pages: 1189-1200

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] HLA-DPβ chain may confer the susceptibility to hepatitis C virus-associated hypertrophic cardiomyopathy2007

    • Author(s)
      Shichi D
    • Journal Title

      Int J immunogenetics 35

      Pages: 37-43

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Donner killer immunoglobulin-like receptor(KIR) genotype-patient cognate KIR lgand combination and antithymocyte globulin preadministration are critical factors in outcome of HLA-C-KIR ligand-mismatched T Cell-replete unrelated bone marrow transplantation2007

    • Author(s)
      Yabe T
    • Journal Title

      Biology of Blood and Marrow Transplantation 14

      Pages: 75-87

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Identification of heat shock protein 70 genes HSPA2,HSPA5 and HSPA8 from the Japanese quail,Coturnix japonica2007

    • Author(s)
      Iwamoto S
    • Journal Title

      Animal.Sci.J. 79

      Pages: 171-181

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] A BAC-based contig map of the cynomolgus macaque(Macaca fascicularis) major histocompatibility complex genomic region2007

    • Author(s)
      Watanabe, A, Shiina, T, Shimizu, S, Hosomichi, K, Yanagiya, K, Kita, YF, Kimura, T, Soeda, E, Toni, R, Ogasawara, K, Kulski, JK, Inoko, H
    • Journal Title

      Genomics 89

      Pages: 402-412

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Effects of a new immunosuppressive agent, beta-SQAG9, in swine kidney transplantation2007

    • Author(s)
      Tanaka, T, Kitamura, H, Sahara, H, Imai, A, Itoh, Y, Honma, I, Sato, E, Kobayashi, K, Maeda, T, Takenouchi, M, Ohta, K, Sugawara, F, Sakaguchi, K, Ando, A, Inoko, H, Sato, N, Tsukamoto, T
    • Journal Title

      Transpl Immunol 18

      Pages: 67-71

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] A third broad lineage of major histocompatibility complex(MHC) class I in teleost fish, MHC class II linkage and processed genes2007

    • Author(s)
      Dijkstra, JM, Katagiri T, Hosomichi K, Yanagiya K, Inoko H, Ototake M, Aoki T, Hashimoto K, Shiina T
    • Journal Title

      Immunogenetics 59

      Pages: 305-321

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Extended gene map reveals tripartite motif, C-type lectin, and Ig superfamily type genes within a subregion of the chicken MHC-B affecting infectious disease2007

    • Author(s)
      Shiina, T, Briles WE, Goto, RM, Hosomichi, K, Yanagiya, K, Shimizu, S, Inoko, H, Miller, MM
    • Journal Title

      J Immunol 178 178

      Pages: 7162-7172

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Synergistic association of mitochondnal uncoupling protein(UCP) genes with schizophrenia2007

    • Author(s)
      Yasuno, K, Ando, S, Misumi, S, Makino, S, Kulski, JK, Muratake, T, Kaneko, N, Amagane, H, Someya, T, Inoko, H, Suga, H, Kanemoto, K, Tamiya, G
    • Journal Title

      Am J Med Genet B Neuropsychiatr Genet 144

      Pages: 250-253

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Two critical genes(HLA-DRB1 and ABCF1) in the HLA region are associated with the susceptibility to autoimmune pancreatitis2007

    • Author(s)
      Ota, M, Katsuyama, Y, Hamano, H, Umemura, T, Kimura, A, Yoshizawa, K, Kryosawa, K, Fukushima, H, Bahram, S, Inoko, H, Kowa, S
    • Journal Title

      Immunogenetics 59

      Pages: 45-52

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] One-step generation of recombineering constructs by asymmetric-end ligation and negative2007

    • Author(s)
      Ohtsuka, M, Mizutani, A, Kikuti, YY, Kulski, JK, Sato, M, Kimura, M, Tanaka, M, lnoko, H
    • Journal Title

      Anal Biochem 360

      Pages: 306-308

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Mapping of susceptibility and protective loci for acute GVHD in unrelated HLA-matched bone marrow transplantation donors and recipients using 155 microsatellite markers on chromosome 222007

    • Author(s)
      Kikuchi, T, Naruse, TK, Onizuka, M, Li, S, Kimura, T, Oka, A, Morishima, Y, Kulski, JK, Ichtmiya, S, Sato, N, Inoko, H
    • Journal Title

      Immunogenetics 59

      Pages: 99-108

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Genes in the HLA region indicative for head and neck squamous cell carcinoma Bahram S, Inoko H : Microsatellite markers for genome-wide association studies2007

    • Author(s)
      Reinders J, Rozemuller EH, van der Weide P, Oka A, Slootweg PJ, Inoko H, Tilanus MG
    • Journal Title

      Mol Immunol 44

      Pages: 848-855

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] 「研究成果報告書概要(欧文)」より2007

    • Author(s)
      Yatsu, K, Mizuki, N, Hirawa, N, Oka, A, Itoh, N, Yamane, T, Ogawa, M, Shiwa, T, Tabara, Y, Ohno, S, Soma, M, Hata, A, Nakao, K, Ueshima, H, Ogihara, T, Tomoike, H, Miki, T, Kimura, A
    • Journal Title

      Nature Reviews Genetics 8

      Pages: 164-164

    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Inoko H High-resolution mapping for essential hypertension using microsatellite markers2007

    • Author(s)
      Mano, S, Kulski, JK, Umemura, S
    • Journal Title

      Hypertension 49

      Pages: 446-452

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Effects of HLA allele and killer immunoglobulin-like receptor ligand matching on clinical outcome in leukemia patients undergoing transplantation with T-cell-replete marrow from an unrelated donor2007

    • Author(s)
      Monshima, Y, Yabe, T, Matsuo, K, Kashiwase, K, Inoko, H, Sap, H, Yamamoto, K, Maruya, E, Akatsuka, Y, Onizuka, M, Sakamaki, H, Sao, H, Ogawa, S, Kato, S, Juji, T, Sasazuki, T, Kodera, Y
    • Journal Title

      Biol Blood Marrow Transplant 13

      Pages: 315-328

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Exclusion of transforming growth factor-betal as a candidate gene for myopia in the Japanese2007

    • Author(s)
      Hayashi T, Inoko H, Nishizaki R, Ohno S, Mizuki
    • Journal Title

      Jpn J Ophthalmol 51

      Pages: 96-99

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Alternative splicing due to an intronic SNP in HMSD generates a novel minor histocompatibility antigen2007

    • Author(s)
      Kawase, T, Akatsuka, Y, Torikai, H, Monshima, S, Oka, A, Tsujimura, A, Miyazaki, M, Tsujimura, K, Miyamura, K, Ogawa, S, Inoko, H, Morishima, Y, Kodera, Y, Kuzushima, K, Takahashi, T
    • Journal Title

      Blood 110

      Pages: 1055-1063

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] High-risk HLA allele mismatch combinations responsible for severe acute graft versus host disease and implication for its molecular mechanism2007

    • Author(s)
      Kawase, T, Morishima, Y, Matsuo, K, Kashiwase, K, Inoko, H, Saji, H, Kato, S, Juji, T, Kodera, Y, Sasazuki, T
    • Journal Title

      Blood 110

      Pages: 2235-2241

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] The COL1A1 gene and high myopia susceptibility in Japanese2007

    • Author(s)
      Inamori, Y, Ota, M, lnoko, H, Okada, E, Nishizaki, R, Shiota, T, Mok, J, Oka, A, Ohno, S, Mizuki, N
    • Journal Title

      Hum Genet 122

      Pages: 151-157

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Immunological actions of Sophy β-Gllucan(β-1, 3-1, 6 Gulucan), currently available commercially as a health food supplement2007

    • Author(s)
      Ikewaki, N, Fujii, N, Onaka, T, Ikewaki, S, Inoko, H
    • Journal Title

      Microbiol Immunol 51

      Pages: 861-873

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Human leukocyte antigen may predict outcome of primary recurrent spontaneous abortion treated with paternal lymphocyte alloimmunization therapy2007

    • Author(s)
      Kano, T, Mon, T, Furudono, M, Ishikawa, H, Watanabe, H, Kikkawa, E, Warita, T, Onizuka, M, Takahashi, M, Maeda , Y, Naruse, T, Inoko, H, Kimura, A
    • Journal Title

      Am J Reprod Immunol 58

      Pages: 383-387

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Lack of association of Toll-like receptor 9 gene polymorphism with Behcet's disease in Japanese patients2007

    • Author(s)
      Ito, A, Ota, M, Katsuyama, Y, Inoko, H, Ohno, S, Mizuki, N
    • Journal Title

      Tissue Antigens 70

      Pages: 423-426

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Association of autoimmune disease-related gene polymorphisms with chronic graft-versus-host disease2007

    • Author(s)
      Shimada, M, Onizuka, M, Machida, S, Suzuki, R, Kojima, M, Miyamura, K, Kodera, Y, Inoko, H, Ando, K
    • Journal Title

      Br J Haematol 139

      Pages: 458-463

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Single nucleotide polymorphism detection by polymerase chain reaction-restriction fragment length polymorphism2007

    • Author(s)
      Ota, M, Fukushima, H, Kulski, JK, Inoko, H
    • Journal Title

      Nature Protoc 11

      Pages: 2857-2864

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] A single nucleotide polymorphism analysis of the LAMAAI gene in Japanese patients with high myopia2007

    • Author(s)
      Sasaki S, Ota M, Nishizuka R, Okada E, Mok J, Kimura T, Oka A, Katsuyama Y, Ohono S, Inoko H, Mizuki N
    • Journal Title

      Clinical Opthalmology 1

      Pages: 289-295

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Lack of association with high myopia and the MYP2 locus in he Japanese population by high resolution analysis on chromosome 182007

    • Author(s)
      Yamane, T, Mok, J, Nishizuka, R, Oka, A, Nishizaki, R, Meguro, A, Yonemoto, J, Kulski, JK, Ohono, S, Inoko, H, Mizuki, N
    • Journal Title

      Clinical Opthalmology 1

      Pages: 311-316

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Genetic analysis of craniofacial traits in the medaka2007

    • Author(s)
      Kimura, T, Shimada, A, Sakai, N, Mitani, H, Naruse, K, Takeda, H, Inoko, H, Tamiya, G, Shinya, M
    • Journal Title

      Genetics 177

      Pages: 2379-2388

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Decrease in CD93(C1qRp) expression in a human monocyte cell line(U937) treated with various apoptosis-inducing chemical substances2007

    • Author(s)
      Ikewaki, N, Tamauchi, H, Inoko, H
    • Journal Title

      Microbiol Immunol 51

      Pages: 1189-1200

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] HLA-DPβ chain may confer the susceptibility to hepatitis C virus-associated hypertrophic cardiomyopathy2007

    • Author(s)
      Shichi, D, Matsumori, A, Naruse, KT, Inoko, H, Kimura, A
    • Journal Title

      Int J immunogenetics 35

      Pages: 37-43

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] A BAC-based contig map of the cynomolgus macaque(Macaca fasccicularis)major histocompatibnity complex genomic region.2007

    • Author(s)
      A.Watanabe, et. al.
    • Journal Title

      Genomics 89

      Pages: 402-412

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A BAC-based contig map of the cynomolgus macaque (Macaca fascicularis) majc histocompatibility complex genomic region.2007

    • Author(s)
      A.Watanabe
    • Journal Title

      Genomics (In press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The Genomic Sequence and Analysis of the Swine Major Histocompatibility Complex2006

    • Author(s)
      Renard C
    • Journal Title

      Genomics 88

      Pages: 96-110

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Novel cynomolgus macaque Mhc-DPB1 polymorphisms in three South-East Asian populations2006

    • Author(s)
      Sano K
    • Journal Title

      Tissue Antigens 67

      Pages: 297-306

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Construction of a nurse shark(Ginglymostoma cirratum) bacterial artificial chromosome(BAC) library and a preliminary genome survey2006

    • Author(s)
      Luo M
    • Journal Title

      BMC Genomics 7

      Pages: 106-106

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Rapid evolution of MHC class I genes in primates generates new disease alleles in man via hitchhiking diversity2006

    • Author(s)
      Shiina T
    • Journal Title

      Genetics 173

      Pages: 1555-1570

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] The major histocompatibility complex(Mhc)class IIB region has greater genomic structural flexibility and diversity in the quail than the chicken2006

    • Author(s)
      Hosomichi K
    • Journal Title

      BMC Genomics 7

      Pages: 322-322

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] The association between non-melanoma skin cancer and a young dimorphic Aluelement within the major histocompatibility complex class I genomic region2006

    • Author(s)
      Dunn DS
    • Journal Title

      Tissue Antigens 68

      Pages: 127-134

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 同種免疫性流産患者におけるHLA-AとHLA-E遺伝子多型の解析2006

    • Author(s)
      渡辺 浩彦
    • Journal Title

      産婦の進歩 58

      Pages: 136-146

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Regulation of CD93 cell surface expression by protein kinse C isoenzyme2006

    • Author(s)
      Ikewaki I
    • Journal Title

      Microbiol Immunol 50

      Pages: 93-103

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Multiple candidate gene analysis identifies a-synuclein as a susceptibility gene for sporadic Parkinson's disease2006

    • Author(s)
      Mizuta I
    • Journal Title

      Hum Mol Genet 15

      Pages: 1151-1158

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Construction of mouse 129/01a BAC library for the targeting experiments using E14 embryonic stem cells2006

    • Author(s)
      Ohtsuka M
    • Journal Title

      Genes Genet Syst 81

      Pages: 143-146

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Serotonin transporter gene promoter polymorphism and autism:a family-based genetic association study in Japanese population2006

    • Author(s)
      Koishi S
    • Journal Title

      Brain Development 28

      Pages: 257-260

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Four-digit allele genotyping of the HLA-A and HLA-B genes in Japanese patients with Behcet's disease by a PCR-SSOP-Luminex method2006

    • Author(s)
      Itoh Y
    • Journal Title

      Tissue Antigens 67

      Pages: 390-394

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Major histocompatibility complex haplotype is associated with postherpetic pain in mice2006

    • Author(s)
      Sato-Takeda M
    • Journal Title

      Anesthesiology 104

      Pages: 1063-1069

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Augmented induction of CD8+ cytotoxic T-cell response and antitumour resistance by T helper type 1-inducing peptide2006

    • Author(s)
      Kikuchi T
    • Journal Title

      Immunology 117

      Pages: 47-58

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Combination of HLA-A24,-DQA1*03,and -DR9 contributes to acute-onset and early complete {beta}-cell destruction in type 1 diabetes:longitudinal study of residual {beta}-cell function2006

    • Author(s)
      Nakanishi K
    • Journal Title

      Diabetes 55

      Pages: 1862-1868

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Genomewide association analysis of human narcolepsy and a new resistance gene2006

    • Author(s)
      Kawashima M
    • Journal Title

      Am J Hum Genet 79

      Pages: 252-263

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Analysis of single nucleotide polymorphisms at 13 loci within the transforming growth factor-induced factor gene shows no association with high myopia in Japanese subjects2006

    • Author(s)
      Hasumi Y
    • Journal Title

      Immunogenetics 58

      Pages: 947-953

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Tyrosinase gene family and Vogt-Koyanagi-Harada disease in Japanese patients2006

    • Author(s)
      Horie Y
    • Journal Title

      Mol Vis 12

      Pages: 1601-1605

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] The Genomic Sequence and Analysis of the Swine Major Histocompatibility Complex2006

    • Author(s)
      Renard, C, Hart, E, Sehra, H, Beasley, H, Coggill, P, Howe, K, Harrow, J, Sims, S, Rogers, J, Ando, A, Shigenan, A, Shiina, T, Inoko, H, Chardon, P, Beck, S
    • Journal Title

      Genomics 88

      Pages: 96-110

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Novel cynomolgus macaque Mhc-DPB1 polymorphisms in three South-East Asianpopulations2006

    • Author(s)
      Sano, K, Shona, T, Kohara, S, Yanagiya, K, Hosomichi, K, Shimizu, S, Anzai, T, Watanabe, A, Ogasawara, K, Toni, , Jerzy, K Kulska, Inoko, H
    • Journal Title

      Tissue Antigens 67

      Pages: 297-306

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Construction of a nurse shark(Ginglymostoma cirratum) bacterial artificial chromosome(BAC) library and a preliminary genome survey2006

    • Author(s)
      Luo, M, Kim, H, Kudrna, D, Sisneros, NB, Lee, SJ, Mueller, C, Collura, K, Zuccolo, A, Buckingham, EB, Grim, SM, Yanagiya, K, Inoko, H, Shiina, T, Flajnik, MF, Wing, RA, Ohta, Y
    • Journal Title

      BMC Genomics 7

      Pages: 106-106

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Rapid evolution of MHC class I genes in primates generates new disease alleles in man via hitchhiking diversity2006

    • Author(s)
      Shiina, T, Ota, M, Shimizu, S, Katsuyama, Y, Hashimoto, N, Takasu, M, Anzai, T, Kulski, JK, Kikkawa, E, Naruse , T, Kimura, N, Yanagiya, K, Watanabe, A, Hosomichi, K, Kohara, S, Iwamoto, C, Umehara, Y, Meyer, A, Wanner, V, Sano, K, Macquin, C, Ikeo, K, Tokunaga, K, Gojobori, T, lnoko, H, Bahram, S
    • Journal Title

      Genetics 173

      Pages: 1555-1570

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] The major histocompatibility complex(Mhc) class IIB region has greater genomic structural flexibility and diversity in the quail than the chicken2006

    • Author(s)
      Hosomichi, K, Shiina, T, Suzuki, S, Tanaka, M, Shimizu, S, Iwamoto, S, Hara, H, Yoshida, Y, Kulski JK, Inoko, H, Hanzawa, K
    • Journal Title

      BMC Genomics 7

      Pages: 322-322

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] The association between non-melanoma skin cancer and a young dimorphic Alu element within the major histocompatibility complex class I genomic region2006

    • Author(s)
      Dunn, DS, Inoko, H, Kulski, JK
    • Journal Title

      Tissue Antigens 68

      Pages: 127-134

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Regulation of CD93 cell surface expression by protein kinse C isoenzyme2006

    • Author(s)
      Ikewaki, I, Kulski, JK, Inoko, H
    • Journal Title

      Microbiol Immunol 50

      Pages: 93-103

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Multiple candidate gene analysis identifies a-synuclein as a susceptibility gene for sporadic Parkinson's disease2006

    • Author(s)
      Mizuta, I, Satake, W, Nakabayashi, Y, Ito, C, Suzuki, S, Momose, Nagai, Y, Oka, A, Inoko, H, Fukae, J, Saito, Y, Sawabe, M, Murayama, S, Yamamoto, M, Hattori, N, Murata, M, Toda, T
    • Journal Title

      Hum Mol Genet 15

      Pages: 1151-1158

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Construction of mouse 129/Ola BAC library for the targeting experiments using E142006

    • Author(s)
      Ohtsuka, M, Ishii, K, Kikuti, YY, Warita, T, Suszuki, D, Sato, D, Kimura, M, Inoko, H
    • Journal Title

      Genes Genet Syst 81

      Pages: 143-146

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Serotonin transporter gene promoter polymorphism and autism a family-based genetic association study in Japanese population2006

    • Author(s)
      Koishi, S, Yamamoto, K, Matsumoto, H, Koishi, S, Enseki, Y, Oya, A, Asakura, A, Aoki, Y, Atsumi, M, Iga, T, Inomata, J, Inoko, H, Sasaki, T, Nanba, E, Kato, N, Ishii, T, Yamazaki, K
    • Journal Title

      Brain Development 28

      Pages: 257-260

    • NAID

      10020331106

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Four-digit allele genotyping of the HLA-A and HLA-B genes in Japanese patients with Behcet's disease by a PCR-SSOP-Luminex method2006

    • Author(s)
      Itoh, Y, Inoko, H, Kulski, JK, Sasaki, S, Meguro, A, Takiyama, N, Nishida, T, Yuasa, T, Ohno, S, Mizuki, N
    • Journal Title

      Tissue Antigens 67

      Pages: 390-394

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Major histocompatibility complex haplotype is associated with postherpetic pain in mice2006

    • Author(s)
      Sato-Takeda, M, Takasaki, I, Takeda, K, Sasaki, A, Andoh, T, Nojima, H, Shiraki, K, Kuraishi, Y, Hanaoka, K, Tokunaga, K, Yabe, T
    • Journal Title

      Anesthesiology 104

      Pages: 1063-1069

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Augmented induction of CD8+ cytotoxic T-cell response and antitumour resistance by T helper type 1-inducing peptide2006

    • Author(s)
      Kikuchi, T, Uehara, S, Anga, H, Tokunaga, T, Kanyone, A, Tamura, T, Takatsu, K
    • Journal Title

      Immunology 117

      Pages: 47-58

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Combination of HLA-A24, -DQA1 *03, and -DR9 contributes to acute-onset and early complete {beta}-cell destruction in type 1 diabetes longitudinal study of residual {beta}-cell function2006

    • Author(s)
      Nakanishi, K, Inoko, H
    • Journal Title

      Diabetes 55

      Pages: 1862-1868

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] The association between non-melanoma skin cancer and a young dimorphic Alu element within the major histocompatibility complex class I genomic region2006

    • Author(s)
      Dunn, D S, Inoko, H, J.K., Kulski
    • Journal Title

      Tissue Antigens 68

      Pages: 127-134

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Genomewide association analysis of human narcolepsy and a new resistance2006

    • Author(s)
      Kawashima, M, Tamiya, G, Oka, A, Hohjoh, H, Juji, T, Ebisawa, T, Honda, Y, Inoko, H, Tokunaga, K
    • Journal Title

      Am J Hum Genet 79

      Pages: 252-263

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Analysis of single nucleotide polymorphisms at 13 loci within the transforming growth factor-induced factor gene shows no association with high myopia in Japanese subjects2006

    • Author(s)
      Hasumi, Y, Inoko, H, Mano, S, Ota, M, Okada, E, Kulski, JK, Nishizaki, R, Mok, J, Oka, A, Kumagai, N, Nishida, T, Ohno, S, Mizuki, N
    • Journal Title

      Immunogenetics 58

      Pages: 947-953

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Tyrosinase gene family and Vogt-Koyanagi-Harada disease in Japanese patients2006

    • Author(s)
      Hone, Y, Takemoto, Y, Miyazaki, A, Namba, K, Kase, S, Yoshida, K, Ota, M, Hasumi, Y, Inoko, H, Mizuki, N, Ohno, S
    • Journal Title

      Mol Vis 12

      Pages: 1601-1605

    • NAID

      120000947113

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Rapid evolution of major histocompatibility complex class I genes in primate generates new disease alleles in humans via hitchhiking diversity2006

    • Author(s)
      T.Shiina
    • Journal Title

      Genetics 173

      Pages: 1555-1570

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Novel cynomolgus macaque NHC-DPB1 polymorphisms in three South-East Asian populations2006

    • Author(s)
      K.Sano
    • Journal Title

      Tissue Antigens 67

      Pages: 297-306

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Rapid assignment of the swine major histocompatibility complex (SLA) class I and II genotypes in Clawn miniature swine using PCR-SSP and PCR-RFLP methods2005

    • Author(s)
      Ando A
    • Journal Title

      Xenotransplantation 12

      Pages: 121-126

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Development of dense microsatellite markers in the entire SLA region and evaluation of their polymorphisms in porcine breeds2005

    • Author(s)
      Tanaka M
    • Journal Title

      Immunogenetics 57

      Pages: 690-696

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] ニホンウズラMhc(Coja)領域における多型マーカーの設定2005

    • Author(s)
      細道 一善
    • Journal Title

      日本組織適合性学会誌 11

      Pages: 241-251

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Interchromosomal duplication of major histocompatibility complex class I regions in rainbow trout (Oncorhynchus mykiss),a species with presumable recent tetraploid ancestry2005

    • Author(s)
      Shiina T
    • Journal Title

      Immunogenetics 56

      Pages: 878-893

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Genomic evolution of MHC class I region in primates2005

    • Author(s)
      Fukami-Kobayashi K
    • Journal Title

      Proc Natl Acad Sci U S A 102

      Pages: 9230-9234

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Correlation between disparity for microsatellites markers and clinical outcome after unrelated HLA identical hematopietic stem cell transplantation (HSCT)2005

    • Author(s)
      Li S
    • Journal Title

      Tissue Antigens 66

      Pages: 477-477

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] MIC and other NKG2D ligands:from none to too many2005

    • Author(s)
      Bahram S
    • Journal Title

      Curr Opin Immunol. 17

      Pages: 505-509

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Genomic sequence analysis of the 238-kb swine segment with a cluster of TRIM and olfactory receptor genes located,but with no class I genes,at the distal end of the SLA class I region2005

    • Author(s)
      Ando A
    • Journal Title

      Immunogenetics 57

      Pages: 864-873

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Identification and characterization of novel variants of the thioredox in reductase 3 new transcript TXNRD3NT12005

    • Author(s)
      Matsuzaka Y
    • Journal Title

      Mamm Genome 16

      Pages: 41-49

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Augmented induction of CD8+ cytotoxic T-cell response and antitumour resistance by T helper type 1-inducing peptide2005

    • Author(s)
      Tanaka G
    • Journal Title

      Immunogenetics 56

      Pages: 861-870

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Genetic features of Mongolian ethnic groups revealed by Y-chromosomal analysis2005

    • Author(s)
      Katoh T
    • Journal Title

      Gene 346

      Pages: 63-70

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] HLA class II DPB1,DQA1,DQB1,and DRB1 genotypic associations with occupational allergic cough to Bunashimeji mushro2005

    • Author(s)
      Suzuki K
    • Journal Title

      Tissue Antigens 65

      Pages: 459-466

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Analysis of the sequence variations in the Mhc DRB1-like gene of the endangered Humboldt penguin (Spheniscus humboldti)2005

    • Author(s)
      Kikkawa EF
    • Journal Title

      Immunogenetics 57

      Pages: 99-107

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Whole genome association study of rheumatoid arthritis using 27,039 microsatellites2005

    • Author(s)
      Tamiya G
    • Journal Title

      Hum Mol Genetics 14

      Pages: 2305-2321

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] ERVK9,transposons and the evolution of MHC class I duplicons within the alpha-block of the human and chimpanzee2005

    • Author(s)
      Kulski JK
    • Journal Title

      Cytogenetic and Genome Research 110

      Pages: 181-192

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] The haplotype block,NFKBIL1-ATP6V1G2-BAT1-MICB-MICA,within the class III-class I boundary region of the human major histocompatibility complex may control susceptibility to hepatitis C virus-associated dilated cardiomyopathy2005

    • Author(s)
      Shichi D
    • Journal Title

      Tissue Antigens 66

      Pages: 200-208

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Genetic features of Khoton Mongolians revealed by SNP analysis of the Xchromosome2005

    • Author(s)
      Katoh T
    • Journal Title

      Gene 357

      Pages: 95-102

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] High-throughput DNA typing of HLA-A,-B,-C,and -DRB1 loci by a PCR-SSOP-Luminex method in the Japanese population2005

    • Author(s)
      Itoh Y
    • Journal Title

      Immunogenetics 57

      Pages: 1-13

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Genetic linkage map of medaka with polymerase chain reaction length polymorphisms2005

    • Author(s)
      Kimura T
    • Journal Title

      Gene 363

      Pages: 24-31

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Donor fibroblast chimerism in the pathogenic fibrotic lesion of human chronic graft-versus-Host disease2005

    • Author(s)
      Ogawa Y
    • Journal Title

      Investigative Ophthalmology & Visual Science 46

      Pages: 4519-4527

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Gene expression profiling of Japanese psoriatic skin reveals an increased activity in molecular stress and immune response signals2005

    • Author(s)
      Kulski JK
    • Journal Title

      J Mol Med 83

      Pages: 964-975

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] An EYFP insertion mutant containing a modified lox sequence for potential use as a recombination indicator2005

    • Author(s)
      Mizutani A
    • Journal Title

      Nucieic Acid Symposium Series 49

      Pages: 297-298

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] The rise and fall of the CR1 subfamily in the lineage leading to penguins2005

    • Author(s)
      Watanabe M
    • Journal Title

      Gene 365

      Pages: 57-66

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Rapid assignment of the swine major histocompatibility complex(SLA) class I and II genotypes in Clawn miniature swine using PCR-SSP and PCR-RFLP methods2005

    • Author(s)
      T, Miyoshi Y, Fujimura, N, Inoko, H
    • Journal Title

      Xenotransplantation 12

      Pages: 121-126

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Rapid assignment of the swine major histocompatibility complex(SLA) class I and II genotypes in Clawn miniature swine using PCR-SSP and PCR-RFLP methods2005

    • Author(s)
      Ando, A, Ota, M, Sada, M, Katsuyama, Y, Goto, R, Shigenan, A, Kawata, H, Anzai, T, Iwanaga, T, Miyoshi, Y, Fujimura, N, Inoko, H
    • Journal Title

      Xenotransplantation 12

      Pages: 121-126

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Development of dense microsatellite markers in the entire SLA region and evaluation of their polymorphisms in porcine breeds2005

    • Author(s)
      Tanaka, M, Ando, A, Renard, C, Chardon, P, Domukai, M, Okumura, N, Awata, T, Uenishi, H
    • Journal Title

      Immunogenetics 57

      Pages: 690-696

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Interchromosomal duplication of major histocompatibility complex class I regions in rainbow trout(Oncorhynchus mykiss), a species with presumable recent tetraploid ancestry2005

    • Author(s)
      Shiina, T, Dijkstra, JM, Shimizu, S, Watanabe, A, Yanagiya, K, Kiryu, I, Fujiwara, A, Nishida-Umehara, C, Kaba, U, Hirono, I, Yoshiura, Y, Aoki, T, Inoko, H, Kulski, JK, Ototake, M
    • Journal Title

      Immunogenetics 56

      Pages: 878-893

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Genomic evolution of MHC class I region in primates2005

    • Author(s)
      Fukami-Kobayashi, K, Shwa, T, Anzai, T, Sano, K, Yamazaki, M, Inoko, H, Tateno, Y
    • Journal Title

      Proc Natl Acad Sci U S A 102

      Pages: 9230-9234

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Correlation between disparity for microsatellites markers and clinical outcom after unrelated HLA identical hematopietic stem cell transplantation(HSCT)2005

    • Author(s)
      Lu, S, Onizuka, M, Kikuchi, T, Ota, M, Monshima, Y, Ando, A, Inoko, H
    • Journal Title

      Tissue Antigens 66

      Pages: 477-477

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] MIC and other NKG2D ligands from none to too many2005

    • Author(s)
      Bahram, S, Inoko, H, Shiina, T, Radosavljevic, M
    • Journal Title

      Curr Opin Immunol 17

      Pages: 505-509

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Genomic sequence analysis of the 238-kb swine segment with a cluster of TRIM and olfactory receptor genes located, but with no class I genes, at the distal end of the SLA class I region2005

    • Author(s)
      Ando, A, Shigenan, A, Kulski, JK, Renard, C, Chardon, P, Shiina, T, Inoko, H :
    • Journal Title

      Immunogenetics 57

      Pages: 864-873

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Identification and characterization of novel variants of the thioredoxin reductase 3 new transcript TXNRD3NT12005

    • Author(s)
      Matsuzaka, Y, Okamoto, K, Mabuchi, T, hzuka, M, Ozawa, A, Oka, A, Tanya, G, Kuiski, JK, Inoko, H
    • Journal Title

      Mamm Genome 16

      Pages: 41-49

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Augmented induction of CD8+ cytotoxic T-cell response and antitumour resistance by T helper type 1-inducing peptide2005

    • Author(s)
      Tanaka, G, Matsushita, I, Ohashi, J, Tsuchlya, N, Ikushima, S, Oritsu, M, Hpikata, M, Nagata, T, Yamamoto, K, Tokunaga, K, Keicho, N
    • Journal Title

      Immunogenetics 56

      Pages: 861-870

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Genetic features of Mongolian ethnic groups revealed by Y-chromosomal analysis2005

    • Author(s)
      Katoh, T, Munkhbat, B, Tounai, K, Mano, S, Ando, H, Oyungerel, G, Chae, GT, Han H, Jia, GJ, Tokunaga, K, Munkhtuvshun, N, Tamiya, G, Inoko, H
    • Journal Title

      Gene 346

      Pages: 63-70

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] HLA class II DPB1, DQA1, DQB1, and DRB1 genotypic associations with occupational allergic cough to Bunashimeji mushro2005

    • Author(s)
      Suzuki, K, Tanaka, H, Sahara, H, Tanaka, N, Tamura, Y, Naruse, T, Inoko, H, Tsushima, K, Kubo, K, Abe, S, Sato, N
    • Journal Title

      Tissue Antigens 65

      Pages: 459-466

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Analysis of the sequence variations in the Mhc DRB1-like gene of the endangered Humboldt penguin(Spheniscus humboldti)2005

    • Author(s)
      Kikkawa, EF, Tsuda, TT, Naruse, TK, Sumiyama, D, Fukuda, M, Kunta, M, Murata, K, Wilson, RP, Lemaho, Y, Tsuda, M, Kulski, JK, Inoko, H
    • Journal Title

      Immunogenetics 57

      Pages: 99-107

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Whole genome association study of rheumatoid arthritis using 27, 039microsatellites2005

    • Author(s)
      Tanya, G, Shinya, M, Imanish, T, Ikuta, T, Makino, S, Okamoto, K, Furugaki, K, Matsumoto, T, Mano, S, Ando, S, Nozaki, Y, Yukawa, W, Nakashige, R, Yamaguchi, D, Ishibashi, H, Yonekura, M, Nakami, Y, Takayama, S, Endo, T, Saruwatan, T, Yagura, M, Yoshikawa, Y, Fujimoto, K, Oka, A, Chiku, S, Linsen, SEV, Giphart, MJ, Kulski, JK, Fukazawa, T, Hashimoto, H, Kimura, M, Hoshina, Y, Suzuki, Y, Hotta, T, Mochuda, J, Minezaki, T, Komai, K, Shuozawa, S, Taniguchi, A, Yamanaka H, Kamatani, N, Gojobori, T, Bahram, S, Inoko, H
    • Journal Title

      Hum Mol Genetics 14

      Pages: 2305-2321

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] ERVK9, transposons annd the evolution of MHC class I duplicons within the alpha-block of the human and chimpanzee2005

    • Author(s)
      Kulski, JK, Anzai, T, Inoko, H
    • Journal Title

      Cytogenetic and Genome Research 110

      Pages: 181-192

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] The haplotype block, NFKBILI-ATP6V1 G2-BAT1-MICB-MICA, within the class III - class I boundary region of the human major histocompatibility complex may control susceptibility to hepatitis C virus-associated dilated cardiomyopathy2005

    • Author(s)
      Shichi, D, Kikkawa EF, Ota M, Katsuyama Y, Kimura A, Matsumon A, Kulski JK, Naruse TK, Inoko H
    • Journal Title

      Tissue Antigens 66

      Pages: 200-208

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Genetic features of Khoton Mongolians revealed by SNP analysis of the X chromosome2005

    • Author(s)
      Katoh T, Mano S, Munkhbat B, Tounal K, Oyungerel G, Chae GT, Han H, Jia GJ, Tokunaga K, Munkhtuvshin N, Tamiya G, Inoko H
    • Journal Title

      Gene 357

      Pages: 95-102

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] High-throughput DNA typing of HLA-A, -B, -C, and -DRB1 loci by a PCR-SSOP-Lumunex method in the Japanese population2005

    • Author(s)
      Itoh, Y, Muzuku, N, Shimada, T, Azuma, F, Itakura, M, Kashiwase, K, Kikkawa, E, Kulski, JK, Satake, M, Inoko, H
    • Journal Title

      Immunogenetics 57

      Pages: 1-13

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Genetic linkage map of medaka with polymerase chain reaction length polymorphisms2005

    • Author(s)
      Kimura, T, Yoshida, K, Shimada, A, Jindo, T, Sakauzumu, M, Mitani, H, Naruse, K, Takeda, H, Inoko, H, Tamiya, G, Shinya, M
    • Journal Title

      Gene 363

      Pages: 24-31

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Donor fibroblast chimerism in the pathogenic fibrotic lesion of human chronic graft-versus-Host disease2005

    • Author(s)
      Ogawa, Y, Kodama, H, Kameyama, K, Yamazaki, K, Yasuoka, H, Okamoto, S, Inoko, H, Kawakami, Y, Kuwana, M
    • Journal Title

      Investigative Ophthalmology & Visual Science 46

      Pages: 4519-4527

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Gene expression profiling of Japanese psonatic skin reveals an increased activity in molecular stress and immune response signals2005

    • Author(s)
      Kulski, JK, Kenworthy, W, Bellgard, M, Taplin, R, Okamoto, K, Oka, A, Mabuchi, T, Ozawa, A, Tamiya, G, Inoko, H
    • Journal Title

      J Mol Med 83

      Pages: 964-975

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] An EYFP insertion mutant containing a modified lox sequence for potential use as a recombination indicator2005

    • Author(s)
      Mizutani, A, Ostuka, M, Kimira, M, Tanaka, M, Inoko, H
    • Journal Title

      Nucleic Acid Symposium Series 49

      Pages: 297-298

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] The rise and fall of the CR1 subfamily in the lineage leading to penguins2005

    • Author(s)
      Watanabe, M, Nikaido, M, Tsuda, T.T, Inoko, H, Mindell, DP, Murata, K, Okada, N
    • Journal Title

      Gene 365

      Pages: 57-66

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Genomic evolution of MHC class I region in primates2005

    • Author(s)
      Fukami-Kobayashi, K
    • Journal Title

      Proc Natl Acad Sci U S A 102

      Pages: 9230-9234

    • Related Report
      2005 Annual Research Report
  • [Journal Article] MIC and other NKG2D ligands : from none to too many2005

    • Author(s)
      Bahram, S
    • Journal Title

      Curr Opin Immunol 17

      Pages: 505-509

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Interchromosomal duplication of major histocompatibility complex class I regions in rainbow trout (Oncorhynchus mykiss), a species with presumable recent tetraploid ancestry.2005

    • Author(s)
      Shiina T
    • Journal Title

      Immunogenetics (In press)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Nucleotide sequencing analysis of the swine 433-kb genomic segment located between the non-classical and classical SLA class I gene clusters2004

    • Author(s)
      Shigenari A
    • Journal Title

      Immunogenetics 55

      Pages: 695-705

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Identification of two new C4 alleles by DNA sequencing and evidence for a historical recombination of serologically defined C4A and C4B alleles2004

    • Author(s)
      Hui J
    • Journal Title

      Tissue Antigens 63

      Pages: 263-269

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Association of polymorphic MHC microsatellites with GVHD,survival,and leukemia relapse in unrelated hematopoietic stem cell transplant donor/recipient pairs matched at five HLA loci2004

    • Author(s)
      Li S
    • Journal Title

      Tissue Antigens 63

      Pages: 362-368

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Notch4 gene polymorphisms are not associated with autism in Japanese population2004

    • Author(s)
      Koishi S
    • Journal Title

      Am J Med Genet 125B

      Pages: 61-62

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Rapid screening of a novel arrayed medaka (Oryzias latipes) cosmid library2004

    • Author(s)
      Ohtsuka M
    • Journal Title

      Mar Biotechnol 4

      Pages: 173-178

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones2004

    • Author(s)
      Imanishi T
    • Journal Title

      PLoS Biology 1

      Pages: 1-20

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Notes on the maximum likelihood estimation of haplotype frequencies2004

    • Author(s)
      Mano S
    • Journal Title

      Annals of Human Genetics 68

      Pages: 257-264

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Comparative analysis of a 229 kb medaka genomic region,containing that zicl and zic4 genes,with Fugu,and mouse2004

    • Author(s)
      Ohtsuka M
    • Journal Title

      Genomics 83

      Pages: 1063-1071

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] CHOP:Visualization of 'wobbling' and isolation of highly conserved regions from aligned DNA sequences2004

    • Author(s)
      Ohtsuka M
    • Journal Title

      Nucleic Acids Research 32

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Kimura M:Possible roles of zic1 and zic4,identified within the medaka Double anal fin (Da) locus,in dorsoventral patterning of the trunk-tailregion (related to phenotypes of the Da mutant)2004

    • Author(s)
      Ohtsuka M
    • Journal Title

      Mech Dev 121

      Pages: 873-882

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] The MICA5.1 allele is not associated with susceptibility to effects of ultraviolet-B radiation on induction of contact hypersensitivity2004

    • Author(s)
      Niizeki H
    • Journal Title

      J Dermatol Sci 35

      Pages: 221-223

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] hRDH-E2 gene polymorphisms,variable transcriptional start sites,and psoriasis2004

    • Author(s)
      Matsuzaka Y
    • Journal Title

      Mamm Genome 15

      Pages: 668-675

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Major histocompatibility complex class I chain-related gene A in Thaipsoriasis patients:MICA association as a part of human leukocyte antigen-B-Cw haplotypes2004

    • Author(s)
      Romphruk AV
    • Journal Title

      Tissue Antigens 63

      Pages: 547-554

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Molecular analysis of HLA allele frequencies and haplotypes in Baloch of Iran compared with related populations of Pakistan2004

    • Author(s)
      Farjadian S
    • Journal Title

      Tissue Antigens 64

      Pages: 561-577

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Autoreactive CD8+ cytotoxic T lymphocytes to major histocompatibility complex class I chain-related gene A in patients with Behcet's disease2004

    • Author(s)
      Yasuoka H
    • Journal Title

      Arthritis & Rheumamtisms 50

      Pages: 3658-3662

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Novel algorithm for automated genotyping of microsatellites2004

    • Author(s)
      Matsumoto T
    • Journal Title

      Nucleic Acids Res 32

      Pages: 6069-6077

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Integration of microsatellite characteristics in the MHC region:a literature and sequence based analysis2004

    • Author(s)
      Gourraud PA
    • Journal Title

      Tissue Antigens 64

      Pages: 543-555

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Identification,expression analysis and polymorphism of a novel RLTPR gene encoding a RGD motif,tropomodulin domain and proline/leucine-rich regions2004

    • Author(s)
      Matsuzaka Y
    • Journal Title

      Gene 343

      Pages: 291-304

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] ペンギン類フンボルト属のMHC領域における多型解析2004

    • Author(s)
      吉川 枝里
    • Journal Title

      DNA多型 12

      Pages: 27-30

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] マイクロサテライトDNA(STR)を用いた造血幹細胞移植後のキメラリズム解析の有用性に関する研究2004

    • Author(s)
      吉場 史郎
    • Journal Title

      移植 39

      Pages: 556-563

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Evolution of the proto-MHC ancestral region:more evidence for the plesiomorphic organisation of human chromosome 9q34 region2004

    • Author(s)
      Vienne A
    • Journal Title

      Immunogenetics 55

      Pages: 429-436

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] The genomic sequence and comparative analysis of the rat major histocompatibility complex2004

    • Author(s)
      Hurt P
    • Journal Title

      Genome Res. 14

      Pages: 631-639

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary 2004 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparative genomic analysis of two avian -quail and chicken- major histocompatibility complex regions2004

    • Author(s)
      Shiina T
    • Journal Title

      J.Immunol 172

      Pages: 6751-6763

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] An update of the HLA genomic region,loci information and disease associations:20042004

    • Author(s)
      Shiina T
    • Journal Title

      Tissue Antigens 64

      Pages: 631-649

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Rhesus Macaque Class I Duplicon Structures,Organization and Evolution within the Alpha Block of the Major Histocompatibility Complex2004

    • Author(s)
      Kulski JK
    • Journal Title

      Mol Biol Evol. 21

      Pages: 2079-2091

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] MHC class IIB gene sequences and expression in quails (Coturnix japonica)selected for high and low antibody responses2004

    • Author(s)
      Shimizu S
    • Journal Title

      Immunogenetics 56

      Pages: 280-291

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution2004

    • Author(s)
      International Chicken Genome Sequencing Consortium
    • Journal Title

      Nature 432

      Pages: 695-716

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] 血清IgG高低選抜ニホンウズラ系統における機能的MhcクラスIIβ遺伝子の塩基配列解析2004

    • Author(s)
      細道 一善
    • Journal Title

      動物遺伝育種研究 31

      Pages: 3-10

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] HNucleotide sequencing analysis of the swine 433-kb genomic segment located between the non-classical and classical SLA class I gene clusters2004

    • Author(s)
      Shigenan, A, Ando, A, Renard, C, Chardon, P, Shiina, T, Kulski, JK, Yasue, H, Inoko
    • Journal Title

      Immunogenetics 55

      Pages: 695-705

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Identification of two new C4 alleles by DNA sequencing and evidence for a historical recombination of serologically defined C4A and C4B alleles2004

    • Author(s)
      Hui, J, Oka, A, Tomizawa, M, Tay, GK, Kulski, JK, Penhale, WJ, Isachi, SPA, Tamiya, G, Inoko, H
    • Journal Title

      Tissue Antigens 63

      Pages: 263-269

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Notch4 gene polymorphisms are not associated with autism in Japanese population2004

    • Author(s)
      Koishi, S, Yamazaki, K, Yamamoto, K, Koishi, S, Enseki, Y, Nakamura, Y, Oya, A, Yasueda, M, Asakura, A, Aoki, Y, Atsumi, M, Inomata, J, Inoko, H, Matsumoto, H
    • Journal Title

      Am J Med Genet 125

      Pages: 61-62

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Rapid screening of a novel arrayed medaka(Oryzias latipes)cosmid library2004

    • Author(s)
      Ohtsuka, M, Kikuchi, N, Nogami, M, Inoko, H, Ozato, K, Kimura, M
    • Journal Title

      Mar Biotechnol 4

      Pages: 173-178

    • NAID

      10012664857

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Notes on the maximum likelihood estimation of haplotype frequencies2004

    • Author(s)
      Mano, S, Yasuda, N, Katoh, T, Tounai, K, Inoko, H, Imanishi, T, Tamiya, G, Goiobon, T
    • Journal Title

      Annals of Human Genetics 68

      Pages: 257-264

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Comparative analysis of a 229 kb medaka genomic region, containing that zuc1 and zic4 genes, with Fugu, and mouse2004

    • Author(s)
      Ohtsuka, M, Kikuchi, N, Ozato, K, Inoko, H, Kimura, M
    • Journal Title

      Genomics 83

      Pages: 1063-1071

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] CHOP Visualization of 'Wobbling' and isolation of highly conserved regions from aligned DNA sequences2004

    • Author(s)
      Ohtsuka, M, Honuchi, Kulski, JK, Kimura, M, lnoko, H
    • Journal Title

      Nucleic Acids Research 32

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Possible roles of zic1 and zic4, identified within the medaka Double anal fin(Da) locus, in dorsoventral patterning of the trunk-tail region(related to phenotypes of the Da mutant)2004

    • Author(s)
      Ohtsuka, M, Kikuchi, N, Yokoi, H, Kinoshita, M, Wakamatsu, Y, Ozato, K, Takeda, H, Inoko, H, Kimura, M
    • Journal Title

      Mech Dev 121

      Pages: 873-882

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] The MICA5.1 allele is not associated with susceptibility to effects of ultraviolet-B radiation on induction of contact hypersensitivity2004

    • Author(s)
      Nuzeku, H, Matsunaga, T, lwata, T, Shimizu, T, Kunmoto, I, Naruse, T, Inoko, H, Streilein, JW
    • Journal Title

      J Dermatol Sol 35

      Pages: 221-223

    • NAID

      10016184929

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] hRDH-E2 gene polymorphisms, variable transcriptional start sites, and psoriasis2004

    • Author(s)
      Matsuzaka, Y, Okamoto, K, Yoshikawa, Y, Takaki, A, Oka, A, Mabuchi, T, lizuka, M, Ozawa, A, Tamiya, G, Kulski, JK, Inoko, H
    • Journal Title

      Mamm Genome 15

      Pages: 668-675

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Major histocompatibility complex class I chain-related gene A in Thai psoriasis patients MICA association as a part of human leukocyte antigen-B-Cw haplotypes2004

    • Author(s)
      Romphruk, AV, Romphruk, A, Choonhakarn, C, Puapairoj, C, Inoko, H, Leelayuwat, C
    • Journal Title

      Tissue Antigens 63

      Pages: 547-554

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Molecular analysis of HLA allele frequencies and haplotypes in Baloch of Iran compared with related populations of Pakistan2004

    • Author(s)
      Farjadian, S, Naruse, T, Kawata, H, Ghaderi, A, Bahram, S, Inoko, H
    • Journal Title

      Tissue Antigens 64

      Pages: 561-577

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Autoreactive CD8+ cytotoxic T lymphocytes to major histocompatibility complex class I chain-related gene A in patients with Behcet's disease2004

    • Author(s)
      Yasuoka, H, Okazaki, Y, Kawakami, Y, Hirakata, M, Inoko, H, Ikeda, Y, Kuwana, M
    • Journal Title

      Arthritis & Rheumamtisms 50

      Pages: 3658-3662

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Novel algorithm for automated genotyping of microsatellites2004

    • Author(s)
      Matsumoto, T, Yukawa, W, Nozaki, Y, Nakashige, R, Shinya, M, Makino, S, Yagura, M, Ikuta, T, Imanishi, T, Inoko, H, Tamiya, G, Goiobon, T
    • Journal Title

      Nucleic Acids Res 32

      Pages: 6069-6077

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Integration of microsatellite characteristics in the MHC region a literature and sequence2004

    • Author(s)
      Gourraud, PA, Mano, S, Barnetche, T, Carrington, M, Inoko, H, Cambon-Thomsen A
    • Journal Title

      Tissue Antigens 64

      Pages: 543-555

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Identification, expression analysis and polymorphism of a novel RLTPR gene encoding a RGD motif, tropomodulin domain and proline/leucine-rich regions2004

    • Author(s)
      Matsuzaka, Y, Okamoto, K, Mabuchi, T, lizuka, M, Ozawa, A, Oka, A, Tamiya, G, Kulski, JK, Inoko, H
    • Journal Title

      Gene 343

      Pages: 291-304

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Evolution of the proto-MHC ancestral region more evidence for the plesiomorphic organisation of human chromosome 9q34 region2004

    • Author(s)
      Vienne, A, Shiina, T, Abi-Rached, L, Danchin, E, Vitiello, V, Cartault, F, Inoko H, Pontarottu, P
    • Journal Title

      Immunogenetics 55

      Pages: 429-436

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] The genomic sequence and comparative analysis of the rat major histocompatibility complex2004

    • Author(s)
      Hurt, P, Walter, L, Sudbrak, R, Klages, S, Muller, I, Shiina, T, Inoko, H, Lehrach, H, Gunther, E, Reinhardt, R, Himmelbauer, H
    • Journal Title

      Genome Res 14

      Pages: 631-639

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Comparative genomic analysis of two avian -quail and chicken- major histocompatibility complex regions2004

    • Author(s)
      Shiina, T, Shimizu, S, Hosomichi, K, Kohara, S, Watanabe, S, Hanzawa, K, Beck, S, Kulski, JK, Inoko, H
    • Journal Title

      J. Immunol 172

      Pages: 6751-6763

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] An update of the HLA genomic region, loci information and disease associations : 20042004

    • Author(s)
      Shuna, T, Inoko, H, Kulski, JK
    • Journal Title

      Tissue Antigens 64

      Pages: 631-649

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Rhesus Macaque Class I Duplicon Structures, Organization and Evolution within the Alpha Block of the Major Histocompatibility Complex2004

    • Author(s)
      Kulski, JK, Anzai, T, Shona, T, Inoko, H
    • Journal Title

      Mol Buol Evol 21

      Pages: 2079-2091

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] MHC class IIB gene sequences and expression in quails(Coturnix japonica) selected for high and low antibody responses2004

    • Author(s)
      Shimizu, S, Shiina, T, Hosomichi, K, Takahashi, S, Koyama, T, Onodera, T, Kulski, JK, Inoko, H
    • Journal Title

      Immunogenetics 56

      Pages: 280-291

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] International Chicken Genome Sequencing Consortium Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution2004

    • Author(s)
      Ando, A, Ota, M, Sada, M, Katsuyama, Y, Goto, R, Shigenan, A, Kawata, H, Anzai, T, Iwanaga
    • Journal Title

      Nature 432

      Pages: 695-716

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.2004

    • Author(s)
      International Chicken Genome Sequencing Consortium
    • Journal Title

      Nature 432

      Pages: 695-716

    • Related Report
      2004 Annual Research Report
  • [Journal Article] An update of the HLA genomic region, loci information and disease associations : 20042004

    • Author(s)
      Shiina T
    • Journal Title

      Tissue Antigens 64

      Pages: 631-649

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Rhesus Macaque Class I Duplicon Structures, Organization and Evolution within the Alpha Block of the Major Histocompatibility Complex.2004

    • Author(s)
      Kulski JK
    • Journal Title

      Mol Biol Evol. 21

      Pages: 2079-2091

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Comparative genomic analysis of two avian - quail and chicken - major histocompatibility complex regions.2004

    • Author(s)
      Shiina T
    • Journal Title

      J.Immunol 172

      Pages: 6751-6763

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Novel cynomolgus macaque Mhc-DPB1 polymorphisms in three South-East Asian populations

    • Author(s)
      Sano, K
    • Journal Title

      Tissue Antigens (In press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] The Genomic Sequence and Analysis of the Swine Major Histocompatibility Complex

    • Author(s)
      Renard, C
    • Journal Title

      Genomics (In press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Comparative genomics of poultry Mhc region

    • Author(s)
      Shiina, T
    • Journal Title

      Animal Science Journal (In press)

    • Related Report
      2005 Annual Research Report
  • [Presentation] Evolutionary process of the major histocompatibility complex(MHC)regions2008

    • Author(s)
      Shiina T
    • Organizer
      New Insight of Genomic Evolution into Fundamental Life Activities
    • Place of Presentation
      国立情報学研究所
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Comparative genome analysis of the MHC regions in primates2008

    • Author(s)
      Shiina T
    • Organizer
      Non-human primate immunogenetics in 22nd European Immunogenetics and Histocompatibility Conference
    • Place of Presentation
      Toulouse International Congress Center
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Comparative genome analysis of the MHC regions in primates2008

    • Author(s)
      Shiina T
    • Organizer
      22nd European Immunogenetics and Histocompatibility Conference
    • Place of Presentation
      Toulouse International Congress Center
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ニホンウズラのMHCクラスIIB遺伝子領域に関する多様性解析2008

    • Author(s)
      椎名 隆
    • Organizer
      東京農業大学先端研究プロジェクトAシンポジウム
    • Place of Presentation
      東京農業大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Evolutionary process of the major histocompatibility complex(MHC) regions2008

    • Author(s)
      Shiina, T
    • Organizer
      New Insight of Genomic Evolution into Fundamental Life Activities
    • Place of Presentation
      NII
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Comparative genome analysis of the MHC regions in primates2008

    • Author(s)
      Shiina, T
    • Organizer
      Non-human promate immunogenetics in 22nd European Immunogenetics and Histocompatibility Conference
    • Place of Presentation
      Toulouse International Congress Center
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Comparative genome analysis of the MHC regions in primates2008

    • Author(s)
      Shiina, T., Hosomichi, K., Kita, FY., Kono, A., Kurata, R., Shibahara, Y., Sato, K., Kintou, S., Inoko, H
    • Organizer
      22nd European Immunogenetics and Histocompatibility Conference
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 主要組織適合遺伝子複合体(MHC)領域における比較ゲノム解析2007

    • Author(s)
      椎名 隆, ら
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      パシヒコ横浜
    • Year and Date
      2007-12-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] カニクイザルMHC領域に位置するTRIM遺伝子群の多型解析2007

    • Author(s)
      倉田 里穂, ら
    • Organizer
      第30回日本分子生物学会年会・第80回目本生化学会大会 合同大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] コモンマーモセットMHC領域における比較ゲノム解析2007

    • Author(s)
      河野 あづみ, ら
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] Comparative genome analysis of the MHC regions in vertebrate species2007

    • Author(s)
      Shiina T
    • Organizer
      Goettingen Workshop on Immunogenetics
    • Place of Presentation
      German Primate Center
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ニワトリMHCとマレック病2007

    • Author(s)
      椎名 隆
    • Organizer
      第3回動物MHCシンポジウム
    • Place of Presentation
      つくば国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 主要組織適合遺伝子複合体(MHC)領域におけるニワトリを含む脊椎動物の間の比較ゲノム解析2007

    • Author(s)
      椎名 隆
    • Organizer
      日本比較免疫学会第19回学術集会シンポジウム
    • Place of Presentation
      舞阪文化センター
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ニワトリMHCハプロタイプの比較ゲノム解析2007

    • Author(s)
      細道 一善
    • Organizer
      日本進化学会2007年大会
    • Place of Presentation
      京都大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] サメ類におけるMHC遺伝子の進化2007

    • Author(s)
      河野 あづみ
    • Organizer
      日本進化学会2007年大会
    • Place of Presentation
      京都大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 霊長類MHCクラスI領域のゲノム構造の比較とその進化2007

    • Author(s)
      椎名 隆
    • Organizer
      日本進化学会2007年大会
    • Place of Presentation
      京都大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] 主要組織適合性遺伝子複合体(MHC)領域の進化医学的解析2007

    • Author(s)
      椎名 隆
    • Organizer
      国立遺伝学研究所研究会シンポジウム
    • Place of Presentation
      国立遺伝学研究所
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ニホンウズラ主要組織適合性抗原複合体Mhc(Coja)領域におけるハプロタイプ解析2007

    • Author(s)
      鈴木 進悟
    • Organizer
      2007年度日本DNA多型学会大会
    • Place of Presentation
      大阪産業創造館
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ニホンウズラCD1領域の塩基配列決定によるゲノム構造解析2007

    • Author(s)
      鈴木 進悟
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 集団遺伝学的解析によるバンドウイルカ1群内の親子関係2007

    • Author(s)
      北 夕紀
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 主要組織適合遺伝子複合体(MHC)領域における比較ゲノム解析2007

    • Author(s)
      椎名 隆
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] カニクイザルMHC領域に位置するTRIM遺伝子群の多型解析2007

    • Author(s)
      倉田 里穂
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ニワトリMHC領域におけるゲノム多様性解析2007

    • Author(s)
      細道 一善
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] コモンマーモセットMHC領域における比較ゲノム解析2007

    • Author(s)
      河野 あづみ
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 家畜MHC領域の比較ゲノム解析2006

    • Author(s)
      椎名 隆
    • Organizer
      第2回動物MHC研究会シンポジウム
    • Place of Presentation
      九州大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ブタMHC領域のゲノム解析と畜産学分野における応用2006

    • Author(s)
      安藤 麻子
    • Organizer
      第2回動物MHC研究会シンポジウム
    • Place of Presentation
      九州大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ニワトリ第16番染色体のゲノム配列決定によるMHC領域のゲノム解析2006

    • Author(s)
      椎名 隆
    • Organizer
      第106回大会日本畜産学会
    • Place of Presentation
      九州大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ニホンウズラおよびニワトリのTapasin遺伝子の多様性解析2006

    • Author(s)
      田中 政之
    • Organizer
      第106回大会日本畜産学会
    • Place of Presentation
      九州大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] マレック病責任遺伝子同定を目的としたニワトリMHC領域におけるヒッチハイキング領域の多様性解析2006

    • Author(s)
      細道 一善
    • Organizer
      第106回大会日本畜産学会
    • Place of Presentation
      九州大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 新しいブタ近交系デュロック種の特徴と多型解析によるSLAハプロタイプの決定2006

    • Author(s)
      安藤 麻子
    • Organizer
      第15回日本組織適合性学会大会
    • Place of Presentation
      砂防会館
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ほ乳類MHC領域の比較ゲノム解析2006

    • Author(s)
      椎名 隆
    • Organizer
      第15回日本組織適合性学会大会
    • Place of Presentation
      砂防会館
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ブタMHC(SLA)の異なるハプロタイプ間における遺伝子構造の差異2006

    • Author(s)
      上西 博英
    • Organizer
      第15回日本組織適合性学会大会
    • Place of Presentation
      砂防会館
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ブタMHC(SLA)領域内のマイクロサテライトマーカーを用いたSLAホモ/ヘテロ接合体サンプルの多型性解析2006

    • Author(s)
      安藤 麻子
    • Organizer
      日本分子生物学会フォーラム
    • Place of Presentation
      名古屋国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 比較ゲノム解析によるヒトMHC領域の進化2006

    • Author(s)
      椎名 隆
    • Organizer
      日本分子生物学会フォーラム
    • Place of Presentation
      名古屋国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] マーモセットMHC領域のBACコンティグ作成による霊長類MHC領域のゲノム比較2006

    • Author(s)
      河野 あづみ
    • Organizer
      日本分子生物学会フォーラム
    • Place of Presentation
      名古屋国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] バンドウイルカMHC領域のゲノム構造の解明と陸棲哺乳類との比較ゲノム解析2006

    • Author(s)
      渡辺 舞
    • Organizer
      日本分子生物学会フォーラム
    • Place of Presentation
      名古屋国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ニワトリMHC領域におけるゲノム多様性とヒッチハイキング効果との関連性2006

    • Author(s)
      細道 一善
    • Organizer
      日本分子生物学会フォーラム
    • Place of Presentation
      名古屋国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] カニクイザルのミトコンドリア多型解析2006

    • Author(s)
      安西 達也
    • Organizer
      日本分子生物学会フォーラム
    • Place of Presentation
      名古屋国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ニワトリおよびニホンウズラの主要組織適合性抗原複合体クラスIIB遺伝子座の比較解析2006

    • Author(s)
      鈴木 進悟
    • Organizer
      日本分子生物学会フォーラム
    • Place of Presentation
      名古屋国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 集団遺伝学的解析によるバンドウイルカ1群内の親子関係2006

    • Author(s)
      二橋 夕紀
    • Organizer
      日本分子生物学会フォーラム
    • Place of Presentation
      名古屋国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] MHC-移植ドナーと実験動物としてのミニブタ利用2005

    • Author(s)
      安藤 麻子
    • Organizer
      理研シンポジウム
    • Place of Presentation
      理化学研究所
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] MHC領域の比較ゲノム解析2005

    • Author(s)
      椎名 隆
    • Organizer
      理研シンポジウム
    • Place of Presentation
      理化学研究所
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ブタの比較ゲノム学と実験動物としてのミニブタの利用2005

    • Author(s)
      安藤 麻子
    • Organizer
      第52回日本実験動物学会総会
    • Place of Presentation
      タワーホール船堀
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Comparative genome analyses on primate MHC regions by large scale genome sequencing2005

    • Author(s)
      Shiina T
    • Organizer
      International Colloquium on Microsatellites in the human genomic region HLA
    • Place of Presentation
      Toulouse University
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] HLA region in 2005:Genes and its diversity2005

    • Author(s)
      Shiina T
    • Organizer
      International Colloquium on Microsatellites in the human genomic region HLA
    • Place of Presentation
      Toulouse University
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 比較ゲノム解析によるMHC領域の進化2005

    • Author(s)
      椎名 隆
    • Organizer
      第7回日本進化学会
    • Place of Presentation
      東北大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ニワトリ第16番染色体のゲノム配列決定によるMHC領域のゲノム解析2005

    • Author(s)
      椎名 隆
    • Organizer
      第14回日本組織適合性学会大会
    • Place of Presentation
      熊本大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ブタMHC領域内のマイクロサテライトマーカーを用いたSLAホモ接合体サンプルの多型性解析2005

    • Author(s)
      安藤 麻子
    • Organizer
      第14回日本組織適合性学会大会
    • Place of Presentation
      熊本大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ニワトリMHC領域に見出されたヒッチハイキング領域の多様性解析2005

    • Author(s)
      細道 一善
    • Organizer
      第14回日本組織適合性学会大会
    • Place of Presentation
      熊本大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Correlation between disparity for microsatellites markers and clinical outcome2005

    • Author(s)
      Li S
    • Organizer
      第14回日本組織適合性学会大会
    • Place of Presentation
      熊本大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 各種動物のMHC領域の構造と疾病との関連2005

    • Author(s)
      椎名 隆
    • Organizer
      家畜ゲノム国際ワークショップ
    • Place of Presentation
      日本自転車会館ホール
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] MHCクラスI遺伝子の早い進化速度はHitch-hiking diversityにより新しい疾患感受性遺伝子を生成する2005

    • Author(s)
      椎名 隆
    • Organizer
      第28回日本分子生物学会
    • Place of Presentation
      福岡ヤフードーム
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ヒトゲノムにおけるヒッチハイキング領域の検索と他生物種との比較2005

    • Author(s)
      細道 一善
    • Organizer
      第28回日本分子生物学会
    • Place of Presentation
      福岡ヤフードーム
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] カニクイザルMHCクラスII領域におけるマイクロサテライト多型解析2005

    • Author(s)
      小原 栄
    • Organizer
      第28回日本分子生物学会
    • Place of Presentation
      福岡ヤフードーム
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] ブタMHC領域内のマイクロサテライトマーカーを用いた多品種,並びにSLAホモ接合体サンプルの多型性解析2005

    • Author(s)
      安藤 麻子
    • Organizer
      第28回日本分子生物学会
    • Place of Presentation
      福岡ヤフードーム
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] HLA region in 2005 Genes and its diversity2005

    • Author(s)
      T., Shuna, H., Inoko
    • Organizer
      International Colloquium on Microsatellites in the human genomic region HLA
    • Place of Presentation
      Toulouse University
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 比較ゲノム解析によるMHC領域の進化2004

    • Author(s)
      椎名 隆
    • Organizer
      第6回日本進化学会総会
    • Place of Presentation
      東京大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 霊長類におけるMHC領域の比較ゲノム解析2004

    • Author(s)
      椎名 隆
    • Organizer
      第3回霊長類ゲノム研究会
    • Place of Presentation
      国立遺伝学研究所
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 比較ゲノム解析による霊長類HLA-B/C祖先領域の推定2004

    • Author(s)
      椎名 隆
    • Organizer
      第13回日本組織適合性学会大会
    • Place of Presentation
      千里ライフサイエンスセンター
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Comparative genomic analysis of two avian(quail and chicken)major histocompatibility complex regions2004

    • Author(s)
      Shiina T
    • Organizer
      29th International Conference on Animal Genetics
    • Place of Presentation
      明治大学
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Comparative genome analysis of MHC regions elucidated by genomic sequencing2004

    • Author(s)
      Shiina T
    • Organizer
      第34回日本免疫学会総会
    • Place of Presentation
      ロイトン札幌
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] MHC領域における比較ゲノム解析と多様性解析2004

    • Author(s)
      椎名 隆
    • Organizer
      第27回日本分子生物学会大会
    • Place of Presentation
      パシフィコ横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Comparative genomic analysis of two avian(quail and chicken) major histocompatibility complex regions2004

    • Author(s)
      T., Shona, S., Shimizu, K., Hanzawa, J. K., Kulski, H., Inoko
    • Organizer
      29th International Conference on Animal Genetics
    • Place of Presentation
      Meiji University
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 移植, 輸血検査学2004

    • Author(s)
      椎名 隆
    • Total Pages
      10
    • Publisher
      講談社サイエンティフィク
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] ヒトゲノム2004

    • Author(s)
      椎名 隆
    • Total Pages
      6
    • Publisher
      中山書店
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary

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Published: 2004-04-01   Modified: 2016-04-21  

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