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A population-based cohort study on serum vitamin-D in association with frailty among the community elderly

Research Project

Project/Area Number 16390187
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionTokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare

Principal Investigator

SUZUKI Takao  Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare, Tokyo Metropolitan Institute of Gerontology, Vice-Director, 東京都老人総合研究所, 副所長 (30154545)

Co-Investigator(Kenkyū-buntansha) YOSHIDA Hideyo  Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare, Tokyo Metropolitan Institute of Gerontology, Senior Research Scientist, 東京都老人総合研究所, 研究副部長 (00242735)
KIM Hunkyung  Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare, Tokyo Metropolitan Institute of Gerontology, Senior Research Scientist, 東京都老人総合研究所, 研究副部長 (20282345)
KWON Jinhee  Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare, Tokyo Metropolitan Institute of Gerontology, Research Scientist, 東京都老人総合研究所, 研究員 (50415494)
YOSHIDA Yuko  Tokyo Metropolitan Foundation for Research on Aging and Promotion of Human Welfare, Tokyo Metropolitan Institute of Gerontology, Research Scientist, 東京都老人総合研究所, 研究員 (30321871)
古名 丈人  財団法人東京都高齢者研究, 福祉振興財団・東京都老人総合研究所, 研究助手 (20238687)
杉浦 美穂  財団法人東京都高齢者研究, 福祉振興財団・東京都老人総合研究所, 研究助手 (30260293)
Project Period (FY) 2004 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥14,000,000 (Direct Cost: ¥14,000,000)
Fiscal Year 2006: ¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 2005: ¥5,300,000 (Direct Cost: ¥5,300,000)
Fiscal Year 2004: ¥5,700,000 (Direct Cost: ¥5,700,000)
KeywordsSerum vitamin D / Sarcopenia / Frailty / Functional capacity / Fall / Elderly / 虚弱化 生活機能
Research Abstract

Vitamin D deficiency characterized by low 25-hydroxy vitamin D [25 (OH) D] levels has been found to be prevalent among the elderly in many regions of the world. To investigate the vitamin D status in elderly community-living person in Japan, we measured 25 (OH) D at a baseline survey of 2004-2006.
As a result, we managed to measure 25 (OH) D of 4,305 elderly persons with age 65 and above living in communities. Major outcomes of the analysis on vitamin-D status are as follows: 1) Seasonal difference of 25 (OH) D ; measurement in summer is significantly higher level than in autumn. 2) Sex difference ; male at any age is significantly higher than female. 3) Institutionalized elderly showed significantly lower level of 25 (OH) D level than community/home-living elderly. And 4) lower level of 25 (OH) D is significantly associated with fall occurrence and decline of fall-related physical fitness.

Report

(4 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • Research Products

    (30 results)

All 2007 2006 2005 2004 Other

All Journal Article (28 results) Book (2 results)

  • [Journal Article] Association between change in bone mineral density and decline in usual walking speed among Japanese community elderly women during 2-year follow-up2007

    • Author(s)
      Kwon J, Suzuki T, Yoshida H, Kim H, Yoshida Y, Iwasa H, Sugiura M, Furuna T
    • Journal Title

      Journal of American Geriatrics Society 55・2

      Pages: 240-244

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] A functional single nucleotide polymorphism in the vitamin-K-dependent gamma-glutamyl carboxylase (Arg325Gln) is associated with bone mineral density in elderly Japanese women2007

    • Author(s)
      Kinoshita H, Nakagawa K, Narusawa K, Suzuki T et al.
    • Journal Title

      Bone 40

      Pages: 451-456

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Association between change in bone mineral density and decline in usual walking speed among Japanese community elderly women during 2-year follow-up.2007

    • Author(s)
      Kwon J, Suzuki T, Yoshida H, Kim H, Yoshida Y, Iwasa H, Sugiura M, Furuna T
    • Journal Title

      Journal of American Geriatrics Society 55(2)

      Pages: 240-244

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] A functional single nucleotide polymorphism in the vitamin-K-dependent gamma-glutamyl carboxylase (Arg325Gln) is associated with bone mineral density in elderly Japanese women.2007

    • Author(s)
      Kinoshita H, Nakagawa K, Narusawa K, Suzuki T et al.
    • Journal Title

      Bone 40

      Pages: 451-456

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Concomitant lower serum albumin and vitamin D levels are associated with decreased objective physical performance among Japanese community-dwelling elderly.2007

    • Author(s)
      Kwon J, Suzuki T, Yoshida H, Kim H, Yoshida Y, Iwasa H et al.
    • Journal Title

      Gerontology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Predictors of Cessation of Regular Leisure-time Physical Activity in Community-dwelling Elderly People. Gerontology.2007

    • Author(s)
      Shimada H, Lord S, Yoshida H, Kim H, Suzuki T
    • Journal Title

      Gerontology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Association between change in bone mineral density and decline in usual walking speed among Japanese community elderly woman during 2-year follow-up2007

    • Author(s)
      Kwon J, Suzuki T, Yoshida H, Kim H, Yoshida Y, Iwasa H, Sugiura M, Furuna T
    • Journal Title

      Journal of American Geriatrics Society 55・2

      Pages: 240-244

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 日本人高齢者における身体機能の縦断的・横断的変化に関する研究-高齢者は若返っているか?-.2006

    • Author(s)
      鈴木隆雄, 權珍嬉
    • Journal Title

      厚生の指標 53・4

      Pages: 1-10

    • NAID

      40007262148

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] 姿勢バランス機能の因子構造 : 臨床的バランス機能検査による検討2006

    • Author(s)
      島田裕之, 内山靖, 原田和宏, 大渕修一, Stephen Lord, 鈴木隆雄
    • Journal Title

      理学療法学 33・5

      Pages: 283-286

    • NAID

      110004798409

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 都市部在住高齢者における尿失禁の頻度および尿失禁に関連する特性 : 要介護予防のための包括的健診(「お達者健診」)についての研究2006

    • Author(s)
      吉田祐子, 金憲経, 岩佐一, 權珍嬉, 杉浦美穂, 古名丈人, 吉田英世, 鈴木隆雄
    • Journal Title

      日本老年医学会誌 44・1

      Pages: 83-89

    • NAID

      10018513356

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] 都市部在住高齢女性における老年症候群の複数徴候保侍者の諸特性と関連要因-要介護予防のための包括的健診「お達者健診」-2006

    • Author(s)
      金憲経, 鈴木隆雄, 吉田英世, 權珍嬉, 岩佐一
    • Journal Title

      日本公衆衛生雑誌 54・1

      Pages: 43-52

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Risk factors for dietary variety decline among Japanese elderly in a rural community : a 8-year follow-up study from TMIG-LISA.2006

    • Author(s)
      Kwon J, Suzuki T, Kumagai S, Yukawa H
    • Journal Title

      European Journal Clinical Nutrition 30

      Pages: 305-311

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 姿勢バランス機能の因子構造 : 臨床的バランス機能調査による検討2006

    • Author(s)
      島田裕之, 内山靖, 原田和宏, 大渕修一, Stephen Lord, 鈴木隆雄
    • Journal Title

      理学療法学 33・5

      Pages: 283-286

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 都市部在住高齢女性における老年症候群の複数徴候保持者の諸特性と関連要因-要介護予防のための包括的健診「お達者健診」-2006

    • Author(s)
      金憲経, 鈴木隆雄, 吉田英世, 權珍嬉, 岩佐一
    • Journal Title

      日本公衆衛生雑誌 54・1

      Pages: 43-52

    • NAID

      10018756388

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Risk factors for dietary variety decline among Japanese elderly in a rural community : a 8-year follow-up study from TMIG-LISA.2006

    • Author(s)
      Kwon J, Suzuki T, Kumagai S, Yukawa H
    • Journal Title

      European Journal Clinical Nutrition. 30

      Pages: 305-311

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 高齢者の介護予防と体力増強2005

    • Author(s)
      鈴木隆雄
    • Journal Title

      Journal of Clinical Rehabilitation 14・1

      Pages: 10-14

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 地域高齢者の包括健康維持に対する新しい健診システム2005

    • Author(s)
      鈴木隆雄
    • Journal Title

      日本老年医学会雑誌 42・3

      Pages: 294-297

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 高齢者における骨密度と脈波速度の関連性についての前向き追跡研究-骨粗鬆症は動脈硬化の促進に関与するか-2005

    • Author(s)
      鈴木隆雄, 吉田英世, 金 憲経
    • Journal Title

      Osteoporosis Japan 13・1

      Pages: 75-77

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Functional Analysis of the Single Nucleotide Polymorphism (787T>C) in the Tissue-Nonspecific Alkaline Phosphatase Gene Assiciated With BMD.2005

    • Author(s)
      Goseki-Sone M, Sogabe N, Fukushi-Irie M, Orimo H, Suzuki T, Nakamura H, Orimo H, Hosoi T
    • Journal Title

      J Bone Miner.Res. 20・5

      Pages: 773-782

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Cognitive function among physically independent very old people in an urban Japanese community.2005

    • Author(s)
      Iwasa H, Gondo Y, Suzuki T et al.
    • Journal Title

      Geriat.Gerontol.Int. 5

      Pages: 248-253

    • NAID

      10018028131

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 高齢者における骨密度と脈波速度の関連性についての前向き追跡研究-骨粗鬆症は動脈硬化の促進に関与するか-2005

    • Author(s)
      鈴木隆雄, 吉田英世, 金憲経
    • Journal Title

      Osteoporosis Japan 13・1

      Pages: 75-77

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 地域在宅高齢者における記憶愁訴の実態把握 要介護予防のための包括的健診(「お達者健診」)についての研究(3)2005

    • Author(s)
      岩佐一, 鈴木隆雄, 吉田祐子, 吉田英世, 金憲経, 古名丈人, 杉浦美穂
    • Journal Title

      日本公衆衛生誌 52・2

      Pages: 176-185

    • NAID

      10014497712

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Randomized controlled trial of exercise intervention for the prevention of falls in community-dwelling elderly Japanese women.2004

    • Author(s)
      Suzuki T, Kim H, Yoshida H, et al.
    • Journal Title

      J Bone Min.Metab 22

      Pages: 602-611

    • NAID

      110004696535

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 地域高齢者における転倒と転倒恐怖感についての研究-要介護予防のための包括的健診(「お達者健診」)の調査より-2004

    • Author(s)
      鈴木隆雄, 岩佐一, 吉田英世, 金憲経, 古名丈人, 杉浦美穂, 吉田祐子
    • Journal Title

      Osteoporosis Japan 12・2

      Pages: 295-298

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Randomized controlled trial of exercise intervention for the prevention of falls in community-dwelling elderly Japanese women.2004

    • Author(s)
      Suzuki T, Kim H, Yoshida H, et al.
    • Journal Title

      J Bone Miner Metabolism 22

      Pages: 602-611

    • NAID

      110004696535

    • Related Report
      2004 Annual Research Report
  • [Journal Article] New intervention program for preventing falls among frail elderly people : The effects of perturbed walking exercise using a bilateral separated treadmill.2004

    • Author(s)
      Shimada H, Obuchi S, Furuna T, Suzuki T
    • Journal Title

      Am.J.Phys.Med.Rehab. 83

      Pages: 493-499

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 地域在住高齢者を対象とした転倒刺激付きトレッドミルトレーニングのバランス機能改善効果-無作為化比較対照試験-2004

    • Author(s)
      大渕修一, 小島基永, 柴 喜崇, 島田裕之, 鈴木隆雄
    • Journal Title

      日本老年医誌 41・4

      Pages: 321-327

    • NAID

      10014384893

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Serumvitamin D level and physical function related falling among the community-dwelling elderly in Japan.

    • Author(s)
      Suzuki T, Kwon J, Yoshida H, et al.
    • Journal Title

      (In submitted)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] 骨組鬆症の予防と治療ガイドライン2006年版2006

    • Author(s)
      鈴木隆雄(共著)
    • Total Pages
      141
    • Publisher
      ライフサイエンス出版
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] 骨粗鬆症の予防と治療ガイドライン2006年版2006

    • Author(s)
      鈴木隆雄(共著)
    • Total Pages
      141
    • Publisher
      ライフサイエンス出版
    • Related Report
      2006 Annual Research Report

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Published: 2004-04-01   Modified: 2016-04-21  

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