| Project/Area Number |
16390336
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | KYOTO UNIVERSITY |
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Principal Investigator |
NAGATA Yasushi Kyoto University, Graduate School of Medicine, Associate Professor, 医学研究科, 助教授 (10228033)
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| Co-Investigator(Kenkyū-buntansha) |
MITSUMORI Michihide Kyoto University, Graduate School of Medicine, Lecturer, 医学研究科, 講師 (10263089)
MIZOWAKI Takashi Kyoto University, Graduate School of Medicine, Lecturer, 医学研究科, 講師 (90314210)
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| Project Period (FY) |
2004 – 2005
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| Project Status |
Completed (Fiscal Year 2005)
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| Budget Amount *help |
¥6,400,000 (Direct Cost: ¥6,400,000)
Fiscal Year 2005: ¥1,700,000 (Direct Cost: ¥1,700,000)
Fiscal Year 2004: ¥4,700,000 (Direct Cost: ¥4,700,000)
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| Keywords | Stereotactic body radiation therapy / Four-dimensional radiotherapy / Lung cancer / Body frame / Respiratory gating / Chest wall censor / 同期照射 / 同期信号 / FDG-PET / 腹壁圧センサー |
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| Research Abstract |
To establish an integrated four-dimensional irradiation system for SBRT (stereotactic body radiation therapy), the following research had been performed.
1.Respiratory gating system
To expand the stereotactic radiotherapy for a patient with poor respiratory function, a gating system is ideal. In this study, a flow and a pressure gated signal generators and a coaching system was established.
2.Image registration for SBRT
The image registration between CT, MRI and FDG (FLT)-PET was performed. The system could be used for both target delineation and evaluation of response.
3.Clinical application of SBRT
As many as 180 patients have been treated with this technique. The clinical results of primary lung cancer and secondary lung cancer was evaluated respectively.
4.JCOG0403
A mutli-institutional phase II study of SBRT for stage I lung cancer is ongoing.
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