• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of re-entrant type hyperthermia system for many different kinds of deep tumor

Research Project

Project/Area Number 16390345
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionMeiji University

Principal Investigator

KATO Kazuo  MEIJI UNIVERSITY, SCHOOL OF SCIENCE AND TECHNOLOGY, PROFESSOR, 理工学部, 教授 (80115104)

Co-Investigator(Kenkyū-buntansha) TSUCHIYA Kazuo  MEIJI UNIVERSITY, SCHOOL OF SCIENCE AND TECHNOLOGY, PROFESSOR, 理工学部, 教授 (00090100)
Project Period (FY) 2004 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥11,800,000 (Direct Cost: ¥11,800,000)
Fiscal Year 2006: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 2005: ¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 2004: ¥8,600,000 (Direct Cost: ¥8,600,000)
Keywordshyperthermia / deep tumor / resonant mode / 3-D finite element method / resonant cavity / resonant frequency / noncontact / leaked electromagnetic field / 非接触加温 / 加温パターン / 漏れ電界 / 臨床試験 / 糖尿病 / 非接触深部加温 / 寒天ファントム / 環境 / 漏れ電磁波 / 深部加温 / 多種部位 / 形状可変空胴共振器 / インピーダンス整合器 / 広帯域高周波電源装置
Research Abstract

In this research, a new re-entrant type hyperthermia system was developed to heat many different kinds of deep tumor without contact. Below, the main results of this research are shown.
(1) The electromagnetic field and temperature distributions inside the cavity were estimated by 3-D FEM. From these results, it was shown that the proposed heating method was useful for deep tumor hyperthermia.
(2) The re-entrant resonant cavity type hyperthermia system for deep tumors was designed and constructed based on the computer simulations.
・Developed system consists of a cavity, impedance matching unit, an RF amplifier, an antenna, a computer.
・From the results of computer simulations and experimental heating, it was possible to heat the deep tumor of about 2-5cm in diameter by using the different resonance modes (TM010 and TM012-like-modes) without contact.
・Moving the position of the object, the position of maximum temperature could be controlled.
・Comparing the computer simulation and the experimental results, resonant frequencies agreed with each other with an error of 1% or less, and temperature distributions agreed with each other with an error of 10%.
(3) The influence of electromagnetic waves is a social big problem. Leaked electromagnetic field of the developed system hardly has bad influence on the circumference
It was found that the proposed heating system could be applicable to heat many different kinds of tumors, noncontact, corresponding to the size and that position where it occurred.

Report

(4 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • Research Products

    (23 results)

All 2006 2005 2004

All Journal Article (23 results)

  • [Journal Article] Experimental heating properties of re-entrant type resonant cavity applicator for deep tumor hyperthermia2006

    • Author(s)
      A.Nakano, K.Kato, K.Tsuchiya, et al.
    • Journal Title

      Proc. of the 28^<th> Annual International Conference of the IEEE EMBS EMBC2006

      Pages: 4058-4061

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Design and Construction of Resonant Cavity Applicater for Brain Tumor Hyperthermia Treatment without Contanct2006

    • Author(s)
      Y.Takahashi, K.Kato, K.Tsuchiya, et al.
    • Journal Title

      Proc. of the 28^<th> Annual International Conference of the IEEE EMBS EMBC2006

      Pages: 4074-4077

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Development of the re-entrant type resonant cavity applicator for brain tumor hyperthermia -Experimental heating results -2006

    • Author(s)
      T.Yabuhara, K.Kato, K.Tsuchiya, et al.
    • Journal Title

      Proc. of the 28^<th> Annual International Conference of the IEEE EMBS EMBC2006

      Pages: 5161-5164

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Development of the re-entrant type resonant cavity applicator for brain tumor hyperthermia-Experimental heating results-2006

    • Author(s)
      T.Yabuhara, K.Kato, K.Tsuchiya, et al.
    • Journal Title

      Proc. of the 28th Annual International Conference of the IEEE EMBS EMBC2006

      Pages: 5161-5164

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Experimental heating properties of re-entrant type resonant cavity applicator for deep tumor hyperthermia2006

    • Author(s)
      A.Nakano, K.Kato, K.Tsuchiya, et al.
    • Journal Title

      Proc. of the 28^th Annual International Conference of the IEEE EMBS EMBC2006

      Pages: 4058-4061

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Design and Construction of Resonant Cavity Applicater for Brain Tumor Hyperthermia Treatment without Contanct2006

    • Author(s)
      Y.Takahashi, K.Kato, K.Tsuchiya, et al.
    • Journal Title

      Proc. of the 28^th Annual International Conference of the IEEE EMBS EMBC2006

      Pages: 4074-4077

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Development of the re-entrant type resonant cavity applicator for brain tumor hyperthermia - Experimental heating results -2006

    • Author(s)
      T.Yabuhara, K.Kato, K.Tsuchiya, et al.
    • Journal Title

      Proc. of the 28^th Annual International Conference of the IEEE EMBS EMBC2006

      Pages: 5161-5164

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 頭部用リエントラント型空胴共振器を用いた多種モードによる加温特性解析2006

    • Author(s)
      新藤康弘, 加藤和夫, 他6名
    • Journal Title

      日本機械学会第17回バイオフロンティア講演会講演論文集 No.06-46

      Pages: 79-80

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 頭部用リエントラント型空胴共振器アプリケータの高周波加温特性2006

    • Author(s)
      岩崎 亮, 加藤和夫, 他6名
    • Journal Title

      日本機械学会第17回バイオフロンティア講演会講演論文集 No.06-46

      Pages: 81-82

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 深部癌加温用リエントラント型アプリケータの加温特性2006

    • Author(s)
      中澤宏次, 中野晃喜, 加藤和夫, 他3名
    • Journal Title

      日本機械学会第18回バイオエンジニアリング講演会 講演論文集 No.05-68

      Pages: 399-400

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 脳腫瘍の非接触温熱治療を目的とした空胴共振器アプリケータの設計・試作2006

    • Author(s)
      高橋慶彦, 加藤和夫, 他3名
    • Journal Title

      日本機械学会第18回バイオエンジニアリング講演会 講演論文集 No.05-66

      Pages: 401-402

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Improvement of the resonant cavity applicator for brain tumor hyperthermia - Experimental heating results -2005

    • Author(s)
      T.Yabuhara, K.Kato, K.Tsuchiya, et al.
    • Journal Title

      Proc. of the 27^<th> Annual International Conference of the IEEE EMBS EMBC2005

      Pages: 1161-1164

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Improvement of the resonant cavity applicator for brain tumor hyperthermia - Computer simulation results -2005

    • Author(s)
      T.Shigihara, K.Kato, K.Tsuchiya, et al.
    • Journal Title

      Proc. of the 27^<th> Annual International Conference of the IEEE EMBS EMBC2005

      Pages: 1297-1300

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Improvement of the resonant cavity applicator for brain tumor hyperthermia-Experimental heating results-2005

    • Author(s)
      T.Yabuhara, K.Kato, K.Tsuchiya, et al.
    • Journal Title

      Proc. of the 27th Annual International Conference of the IEEE EMBS EMBC2005

      Pages: 1161-1164

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Improvement of the resonant cavity applicator for brain tumor Hyperthermia -Experimental heating results-2005

    • Author(s)
      T.Yabuhara, K.Kato, K.Tsuchiya, et al.
    • Journal Title

      Proceedings of the 2005 IEEE EMBC'05

      Pages: 1161-1164

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Improvement of the resonant cavity applicator for brain tumor Hyperthermia -Computer simulation results-2005

    • Author(s)
      T.Shigihara, K.kato, K.Tsuchiya, et al.
    • Journal Title

      Proceedings of the 2005 IEEE EMBC'05

      Pages: 1297-1300

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 頭部加温用空胴共振器アプリケータの加温特性 -コンピュータ・シミュレーション-2005

    • Author(s)
      鴫原 健, 薮原忠雄, 加藤和夫, 他3名
    • Journal Title

      Japanese Journal of Hyperthermic Oncology Vol.21

      Pages: 154-154

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 頭部加温用空胴共振器アプリケータの加温特性 -加温実験-2005

    • Author(s)
      薮原忠雄, 鴫原 健, 加藤和夫, 他3名
    • Journal Title

      Japanese Journal of Hyperthermic Oncology Vol.21

      Pages: 155-155

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 非接触温熱治療を目的とした空胴共振器アプリケータの加温特性2005

    • Author(s)
      藪原忠雄, 小原隆宏, 嶋原健, 加藤和夫, 土屋一雄, 高橋英明, 宇塚岳夫, 田中隆一
    • Journal Title

      日本機械学会第17回バイオエンジニアリング講演会講演論文集 No.04-48

      Pages: 299-300

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 深部癌の非接触温熱治療を目的とした空胴共振器アプリケータの設計・試作2004

    • Author(s)
      加藤和夫, 和田森 直, 松田甚一, 高橋英明, 宇塚岳夫, 田中隆一
    • Journal Title

      日本設計工学誌 39・11

      Pages: 627-631

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Improvement of the resonant cavity applicator for brain tumor hyperthermia-Computer simulation results-2004

    • Author(s)
      T.Shigihara, K.Kato, K.Tsuchiya, et al.
    • Journal Title

      Proc. of the 27th Annual International Conference of the IEEE EMBS 39・11

      Pages: 1297-1300

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Design and construction of resonant cavity applicator for deep tumor hyperthermia treatment without contact2004

    • Author(s)
      K.Kato, N.Wadamori, J.Matsuda, H.Takahashi, T.Uzuka, R.Tanaka
    • Journal Title

      Journal of Japan Society for Design Engineering 39・11

      Pages: 627-631

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 深部癌の非接触温熱治療を目的とした空胴共振器アプリケータの設計・試作(第3報,試作加温システムによる人体形状寒天ファントムおよび動物の加温実験)2004

    • Author(s)
      加藤和夫, 和田森直, 松田甚一, 高橋英明, 宇塚岳夫, 田中隆一
    • Journal Title

      設計工学会誌 39・11

      Pages: 627-631

    • NAID

      10013767409

    • Related Report
      2004 Annual Research Report

URL: 

Published: 2004-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi