| Project/Area Number |
16390444
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Tokyo Women's Medical University |
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Principal Investigator |
MOMOHARA Shigeki Tokyo Women's Medical University, School of Medicine, lecturer, 医学部, 講師 (00190984)
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| Co-Investigator(Kenkyū-buntansha) |
KAMATANI Naoyuki Tokyo Women' s Medical University, School of Medicine, professor, 医学部, 教授 (00114447)
TOMATSU Taisuke Tokyo Women' s Medical University, School of Medicine, professor, 医学部, 教授 (40112693)
IKARI Katsunori Tokyo Women' s Medical University, School of Medicine, fellow, 医学部, 助手 (80343557)
KOMIYA Koichiro Tokyo Women' s Medical University, School of Medicine, fellow, 医学部, 助手 (10296634)
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| Project Period (FY) |
2004 – 2005
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| Project Status |
Completed (Fiscal Year 2005)
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| Budget Amount *help |
¥13,400,000 (Direct Cost: ¥13,400,000)
Fiscal Year 2005: ¥3,800,000 (Direct Cost: ¥3,800,000)
Fiscal Year 2004: ¥9,600,000 (Direct Cost: ¥9,600,000)
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| Keywords | genome / microarray / gene / 遺伝子発現プロファイル / 滑膜 / 原因遺伝子 / 関節リウマチ / 軟骨 |
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| Research Abstract |
This study was planned to identify disease-related genes of rheumatoid arthritis (RA) using a two-step systematic approach : (i) the use of gene expression profiling to identify candidate genes for RA susceptibility, and (ii) the use of reported genome-wide scan to narrow the potential region of interest. This is the broad study of rheumatoid arthritis to date and has resulted in the identification of RA-associated genes in Japanese RA patients.
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