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Development of Mechatronic Measurement System for Local Property of Biological Gel

Research Project

Project/Area Number 16500306
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionOsaka Institute of Technology

Principal Investigator

HASHIMOTO Shigehiro  Osaka Institute of Technology, Faculty of Engineering, Professor, 工学部, 教授 (00146515)

Project Period (FY) 2004 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 2006: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2005: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2004: ¥800,000 (Direct Cost: ¥800,000)
KeywordsBiomedical Engineering / Biomeasurement / Mechatronic property / Biological gel / Electric impedance / Electrode / Vibration / 電気インピーダンス / 生体組織 / 粘性係数 / 周波数 / バイオメカニクス
Research Abstract

Local property of biological gel was evaluated with the newly proposed mechatronic measurement system. Impedance between two electrodes soaked in an electrolyte solution varies with the distance between them. When the distance oscillates sinusoidally with a mechanically vibrating electrode, the impedance oscillates, too. The oscillation corresponds to the variation of impedance of the local space, where the electrode is vibrating. The variation was analyzed with spectrum and the amplitude at the corresponding frequency was measured. The electrode was made of a glass micro-capillary (0.01 mm diameter) filled with a potassium chloride aqueous solution (3 mol/L). One of the electrodes was vibrated with a piezoelectric actuator. The measurement system consists of an oscillator, an amplifier, a spectrum analyzer, a phase-contrast optical microscope, a charge-coupled device camera. The manufactured system was applied to measure electrolytes : the sodium chloride aqueous solution, the potassi … More um chloride aqueous solution, a quail egg, and human blood at 25 degrees centigrade. Variation was made in the viscosity of the solution with dextran. The experimental data show that impedance increases with the decrease in the concentration of sodium chloride in the solution from 9.0 to 0.1 percent, and with the increase in the amplitude of vibration of the electrode to 0.023 mm. The experiment with a quail egg shows that the impedance is independently measured of that of the surroundings, when the electrode stuck into the yolk is vibrating : while the impedance varies with the concentration of electrolyte in the surroundings, when the electrode is not vibrating. The impedance increases with viscosity at higher frequency (>100 Hz), and with frequency at higher viscosity (>0.01 Pa s). The result with human blood shows that impedance of the blood varies with coagulation process. The experimental data show that the designed system is effective to evaluate local mechatronic property of biological gel. Less

Report

(4 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • Research Products

    (12 results)

All 2006 2005 2004

All Journal Article (12 results)

  • [Journal Article] Measurement of Mechatronic Property of Blood during Coagulation with Micro-Vibrating Electrode2006

    • Author(s)
      S.Hashimoto, T.Furukawa, et al.
    • Journal Title

      Proc. 10^<th> World Multiconference on Systemics Cybernetics and Informatics 4

      Pages: 177-180

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effect of Viscosity on Local Impedance of Biological Gel : Measurement with Micro-Vibrating Electrode2006

    • Author(s)
      T.Okamoto, S.Hashimoto, et al.
    • Journal Title

      Proc. 20th Congress of the International Society of Biomechanics

      Pages: 507-507

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Measurement of Mechatronic Property of Blood during Coagulation with Micro-Vibrating Electrode2006

    • Author(s)
      S.Hashimoto
    • Journal Title

      Proc. 10^<th> World Multiconference on Systemics Cybernetics and Informatics Vol.4

      Pages: 177-180

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Measurement of Mechatronic Property of Blood during Coagulation with Micro-Vibrating Electrode2006

    • Author(s)
      S.Hashimoto, T.Furukawa
    • Journal Title

      Proc.10^th World Multiconference on Systemics Cybernetics and Informatics 4

      Pages: 177-180

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Measurement of Mechatronic Property of Biological Gel with Micro-Vibrating Electrode2005

    • Author(s)
      T.Furukawa, S.Hashimoto, et al.
    • Journal Title

      Proc. 2nd International Conference on Cybernetics and Information Technologies, Systems and Applications 1

      Pages: 276-280

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Effect of Viscosity on Local Impedance of Biological Gel : Measurement with Micro-Vibrating Electrode2005

    • Author(s)
      T.Okamoto, S.Hashimoto, et al.
    • Journal Title

      Proc. 20th Congress of the International Society of Biomechanics

      Pages: 507-507

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Measurement of Mechatronic Property of Biological Gel with Micro-Vibrating Electrode2005

    • Author(s)
      T.Furukawa, S.Hashimoto, et al.
    • Journal Title

      Proc. 2nd International Conference on Cybernetics and Information Technologies, Systems and Applications Vol.1

      Pages: 276-280

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Measurement of Mechatronic Property of Biological Gel with Micro-Vibrating Electrode2005

    • Author(s)
      Takatsugu Furukawa, Shigehiro Hashimoto
    • Journal Title

      Proc.2nd International Conference on Cybernetics and Information Technologies, Systems and Applications 1

      Pages: 276-280

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Effect of Viscosity on Local Impedance of Biological Gel : Measurement with Micro-Vibrating Electrode2005

    • Author(s)
      Takayuki Okamoto, Shigehiro Hashimoto
    • Journal Title

      Proc.20th Congress of the International Society of Biomechanics

      Pages: 507-507

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Measurement System for Mechatronic Property of Biological Electrolyte Solution with Micro-Vibrating Electrode2004

    • Author(s)
      T.Sekiyama, S.Hashimoto, et al.
    • Journal Title

      Proc. 8^<th> World Multiconference on Systemics Cybernetics and Informatics 7

      Pages: 199-203

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Measurement System for Mechatronic Property of Biological Electrolyte Solution with Micro-Vibrating Electrode2004

    • Author(s)
      T.Sekiyama, S.Hashimoto, et al.
    • Journal Title

      Proc. 8^<th> World Multiconference on Systemics Cybernetics and Informatics Vol.7

      Pages: 199-203

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Measurement System for Mechatronic Property of Biological Electrolyte Solution with Micro-Vibrating Electrode2004

    • Author(s)
      Takayuki Sekiyama, Shigehiro Hashimoto
    • Journal Title

      Proc.8th World Multiconference on Systemics Cybernetics and Informatics 7

      Pages: 199-203

    • Related Report
      2004 Annual Research Report

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Published: 2004-04-01   Modified: 2016-04-21  

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