| Project/Area Number |
16591049
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Iwate Medical University |
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Principal Investigator |
OYAMA Kotaro Iwate Medical University, School of Medicine, Professor, 医学部, 教授 (80170398)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHIOKA Kunihiro Iwate Medical University, School of Medicine, Associate Professor, 医学部, 助教授 (70210648)
TAKAHASHI Shin Iwate Medical University, School of Medicine, Assistant Professor, 医学部, 講師 (10337149)
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| Project Period (FY) |
2004 – 2006
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| Project Status |
Completed (Fiscal Year 2006)
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| Budget Amount *help |
¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 2006: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2005: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2004: ¥1,600,000 (Direct Cost: ¥1,600,000)
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| Keywords | Congenital Heart Disease / MR Angiography / Contrast Medium |
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| Research Abstract |
Background : Fast imaging employing steady state acquisition (FIESTA) has been reported to be suitable for evaluation of adult congenital heart disease.
Purpose : To assess the applicability and limitation of MR, angiography using FIESTA in the diagnosis of congenital heart disease in children.
Methods : One hundred eleven patients with congenital heart disease underwent MR angiography using FIESTA and the 3D Gd-enhanced fast SPGR technique after parental informed consent. The measurements of the vascular diameters and diagnostic accuracy of the two techniques were compared.
Results : Correlations between FIESTA and the 3D Gd-enhanced fast SPGR technique were excellent in measurement of vascular diameter. The agreement of the vascular diameters in the Bland-Altman method was good. However, MR angiography by 3D Gd-enhanced fast SPGR had a higher resolution than that by FIESTA. Due to signal loss caused at the regions of vascular stenos is or Blalock-Tausig shunt on FIESTA, we could not evaluate the vascular diameter or patency at those lesions.
Conclusion : FIESTA is a useful technique of non-enhanced MR. angiography for non-invasive diagnosis of congenital heart disease in children. However, MR angiography by FIESTA was not adequate for evaluation of vascular stenosis.
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