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Stereotactic radiotherapy for lung cancer ; evaluation of tumor viability

Research Project

Project/Area Number 16591209
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionKyushu University

Principal Investigator

SAKAI Shuji  Kyushu University, Faculty of Medicine, Associate professor (90225756)

Co-Investigator(Kenkyū-buntansha) SHIOYAMA Yoshiyuki  Kyushu University, University Hospital, Assistant Professor (10323304)
MATSUO Yoshio  Kyushu University, University Hospital, Assistant professor (50419595)
HONDA Hiroshi  Kyushu University, Faculty of Medicine, professor (90145433)
ABE Koishiro  Kyushu University, University Hospital, Assistant Professor (00380387)
NAKAMURA Kazumasa  Kyushu University, University Hospital, Assistant Professor (20284507)
古賀 博文  九州大学, 大学病院, 助教 (90343318)
添田 博康  九州大学, 大学病院, 助手 (90335969)
Project Period (FY) 2004 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥3,730,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2006: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2005: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2004: ¥800,000 (Direct Cost: ¥800,000)
KeywordsLung Cancer / Stereotactic Radiotherapy / Computed Tomography / Magnetic Resonance Imaging / FDG-PET / Prognosis / 磁気共鳴画像 / 定位的放射線療法
Research Abstract

Finally, 32 patients with primary lung cancer and 13 patients with metastatic lung cancer were submitted to present study. Stereotactic radiotherapy was performed by using linac device which was equipped respiratory gated system. And, we used the stereotactic body frame to suppress the chest and abdominal wall mothion. Stereotactic radiotherapy method in Kyushu University Hospital conformed to clinical trial study of Japan Clinical Oncology Group (JCOG) and maintained the quality control and assurance. On almost patients, the air-space consolidations according to a radiation field with peripheral ground grass attenuation were seen as HRCT findings. These findings appeared at three or six months after from beginning of stereotactic radiotherapy. And, the greater part of these opacities had vanished a few months later.
During the research period, we focused on several classes of graph-structured patterns which represent structural features common to graph-structured data in real-world databases. The followings are main results of this research.

Report

(5 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • Research Products

    (41 results)

All 2008 2007 2006 2005 2004 Other

All Journal Article (30 results) (of which Peer Reviewed: 6 results) Presentation (8 results) Book (3 results)

  • [Journal Article] Integration of Temporal Subtraction and Nodule Detection System for Digital Chest Radiographs into Picture Archiving and Communication System(PACS):Four-year Experience2008

    • Author(s)
      Sakai S, Yabuuchi H, et. al.
    • Journal Title

      J Digit Imaging 21

      Pages: 91-98

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Integration of temporal subtraction and nodule detection system for digital chest radiographs into PACS : four-year experience2008

    • Author(s)
      Sakai, S., Yabuuchi, H., Matsuo, Y., et. al.
    • Journal Title

      J Digit Imaging 21

      Pages: 91-98

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Integration of Temporal Subtraction and Nodule Detection System for Digital Chest Radiographs into Picture Archiving and Communication System(PACS):Four-year Experience2008

    • Author(s)
      Sakai S, Yabuuchi H, Matsuo Y, et. al.
    • Journal Title

      J Digit Imaging 21

      Pages: 91-98

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Automated method for identification of patients with Alzheimer's disease based on three-dimensional MR images2008

    • Author(s)
      Arimura H, Yoshiura T, Kumazawa S, Tanaka K, Koga H, Mihara F, Honda H, Sakai S, et. al.
    • Journal Title

      Acad Radiol 15

      Pages: 274-284

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of masses and microcalcifications of breast cancer on digital mammograms:comparison among hard copy film,3-megapixel liquid crystal display(LCD)monitors and 5-megapixel LCD monitors:an observer performance study2007

    • Author(s)
      Kamitani T, Yabuuchi H, Soeda H, Matsuo Y, Okafuji T, Sakai S, et. al.
    • Journal Title

      Eur Radiol. 17

      Pages: 1365-1371

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Computer-Aided Nodule Detection on Digital Chest Radiography:Validation Test on Consecutive T1 Cases of Resectable Lung Cancer2006

    • Author(s)
      Sakai S, Soeda H, Takahashi N, et. al.
    • Journal Title

      J Digit Imaging 19

      Pages: 376-382

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Evaluation of the Image Quality of Temporal Subtraction Images Produced Automatically in a PACS Environment2006

    • Author(s)
      Sakai S, Soeda H, Akio F, et. al.
    • Journal Title

      J Digit Imaging 19

      Pages: 383-390

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Computer-Aided Nodule Detection on Digital Chest Radiography : Validation Test on Consecutive T1 Cases of Resectable Lung Cancer2006

    • Author(s)
      Sakai, S., Soeda, H., Takahashi, N., et. al.
    • Journal Title

      J Digit Imaging 19

      Pages: 378-382

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Evaluation of the Image Quality of Temporal Subtraction Images Produced Automatically in a PACS Environment2006

    • Author(s)
      Sakai, S., Soeda, H., Furuya, A., et. al.
    • Journal Title

      J Digit Imaging 19

      Pages: 383-390

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Pulmonary Lesions Associated with Visceral Larva Migrans due to Ascaris Suum or Toxocara Canis : Image Findings in Six Cases2006

    • Author(s)
      Sakai, S., Shida, Y., Takahashi, N., et. al.
    • Journal Title

      AJR 186

      Pages: 1697-1702

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] A case of pulmonary synovial sarcoma diagnosed with detection of chimera gene Imaging findings2006

    • Author(s)
      Matsuo Y., Sakai, S., Yabuuchi, H., et. al.
    • Journal Title

      Clin Imaging. 30

      Pages: 60-62

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Pulmonary Lesions Associated with Visceral Larva Migrans Due to Ascaris suum or Toxocara canis : Imaging of Six Cases2006

    • Author(s)
      Sakai S, Shida Y, Takahashi N, et al.
    • Journal Title

      AJR 186・6

      Pages: 1697-1702

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Evaluation of the Image Quality of Temporal Subtraction Images Produced Automatically in a PACS Environment2006

    • Author(s)
      Sakai S, Soeda H, Akio F, et al.
    • Journal Title

      J Digit Imaging 19・4

      Pages: 383-390

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Computer-Aided Nodule Detection on Digital Chest Radiography : Validation Test on Consecutive T1 Cases of Resectable Lung Cancer2006

    • Author(s)
      Sakai S, Soeda H, Takahashi N, et al.
    • Journal Title

      J Digit Imaging 19・4

      Pages: 376-382

    • Related Report
      2006 Annual Research Report
  • [Journal Article] MR imaging features of pure mucinous carcinoma of the breast.2006

    • Author(s)
      Okafuji T, Yabuuchi H, Sakai S, et al.
    • Journal Title

      Eur J Radiol 60・3

      Pages: 405-413

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Pulmonary Lesions Associated with Visceral Larva Migrans Due to Ascaris suum or Toxocara canis : Imaging of Six Cases2006

    • Author(s)
      Sakai S, Shida Y, Takahashi N, et al.
    • Journal Title

      AJR 186・6(In press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] A case of pulmonary synovial sarcoma diagnosed with detection of chimera gene Imaging findings.2006

    • Author(s)
      Matsuo Y, Sakai S, Yabuuchi H, et al.
    • Journal Title

      Clin Imaging 30・1

      Pages: 60-62

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Multifocal Nodular Lymphoid Hyperplasia of the Lung2005

    • Author(s)
      Kajiwara, S., Sakai, S., Soeda, H., et. al.
    • Journal Title

      J Thorac Imaging 20

      Pages: 239-241

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Multifocal Nodular Lymphoid Hyperplasia of the Lung2005

    • Author(s)
      Kajiwara S, Sakai S, Soeda H, et al.
    • Journal Title

      J Thorac Imaging 20・3

      Pages: 239-241

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 経皮肺細胞診・生検による肺腫瘤の良悪性の鑑別2005

    • Author(s)
      坂井修二
    • Journal Title

      断層映像研究会雑誌 32・3

      Pages: 122-127

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Multiple nodular lymphoid hyperplasia of the lung : a case report2005

    • Author(s)
      Kajiwara S, Sakai S, Soeda H, et al.
    • Journal Title

      J Thorac Imaging (In press)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Pulmonary metastasis from pancreatic cancer : a case showing biphasic radiological and histological patterns2004

    • Author(s)
      Okafuji, T., Sakai, S., Yoshimitsu, K., et. al.
    • Journal Title

      CMIG Extra : Cases 28

      Pages: 68-71

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Risk Factor of Radiation Pneumonitis : Assessment with Velocity-Encoded Cine Magnetic Resonance Imaging of Pulmonary Artery.2004

    • Author(s)
      Murayama S, Akamine T, Sakai S, et al.
    • Journal Title

      J Comput Assist Tomogr 28巻2号

      Pages: 204-208

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Pulmonary cryptococcosis in immunocompetent patients ; HRCT characteristics2004

    • Author(s)
      Murayama S, Sakai S, Soeda H, et al.
    • Journal Title

      Clinical Imaging 28巻3号

      Pages: 191-195

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Pulmonary metastasis from pancreatic cancer : a case showing biphasic radiological and histological patterns2004

    • Author(s)
      Okafuji T, Sakai S, Yoshimitsu K, et al.
    • Journal Title

      CMIG Cases 28巻

      Pages: 68-71

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 胸部単純X腺画像-デジタル撮影装置の現況と臨床への応用-2004

    • Author(s)
      坂井修二, 添田博康, 高橋直幹, 他
    • Journal Title

      日本胸部臨床 63巻6号

      Pages: 540-548

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 高分解能CTによるびまん性肺疾患の鑑別診断:総論2004

    • Author(s)
      坂井修二, 添田博康, 高橋直幹, 他
    • Journal Title

      呼吸 23巻8号

      Pages: 289-293

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Integration of Temporal Subtraction and Nodule Detection System for Digital Chest Radiographs into Picture Archiving and Communication System (PACS) : Four-year Experience.

    • Author(s)
      Sakai S, Yabuuchi H, Matsuo Y, et al.
    • Journal Title

      J Digit Imaging (In press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Evaluation of the Image Quality of Temporal Subtraction Images Produced Automatically in a PACS Environment

    • Author(s)
      Sakai S, Soeda H, Akio F, et al.
    • Journal Title

      J Digit Imaging (In press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Computer-Aided Nodule Detection on Digital Chest Radiography : Validation Test on Consecutive T1 Cases of Resectable Lung Cancer

    • Author(s)
      Sakai S, Soeda H, Takahashi N, et al.
    • Journal Title

      J Digit Imaging (In press)

    • Related Report
      2005 Annual Research Report
  • [Presentation] 原発性肺癌に対する3次元集光照射再発に関連する治療前CT所見の検討2007

    • Author(s)
      松尾 芳雄, 坂井 修二, 他
    • Organizer
      第48回日本肺癌学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2007-11-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] Digital Radiography : Clinical Applications and Our Trials2007

    • Author(s)
      S., Sakai
    • Organizer
      The 3rd Joint Meeting of Korean and Japanese Society of Thoracic Radiolog
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Pulmonary involvement of Visceral Larva Migrans due to Ascaris Suum or Toxocara Canis : clinical manifestation and image findings in six cases.2005

    • Author(s)
      Sakai, S., Shida, Y., Yabuuchi, H., et. al.
    • Organizer
      1st world congress of thoracic imaging and diagnosis in chest disease
    • Place of Presentation
      Florence in Italy
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Computer-aided lung nodule detection on digital chest radiography:evaluation of consecutive T1-cases of resected lung cancer2004

    • Author(s)
      Sakai S, Soeda H, Takahashi N, et. al.
    • Organizer
      90th scientific assembly and annual meeting of RSNA
    • Place of Presentation
      Chicago
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Interactive interpretation of chest radiographs by use of CAD systems for temporal subtraction and nodule detection2004

    • Author(s)
      Sakai, S., Yabuuchi, H., Soeda, H., et. al.
    • Organizer
      90th scientific assembly and annual meeting of RSNA
    • Place of Presentation
      Chicago
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Subtle interval change in various clinical situation on temporal subtraction images : comparison with CT findings2004

    • Author(s)
      Sakai, S., Yabuuchi, H., Soeda, H., et. al.
    • Organizer
      90th scientific assembly and annual meeting of RSNA
    • Place of Presentation
      Chicago
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Computer-aided lung nodule detection on digital chest radiography : evaluation of consecutive T1-cases of resected lung cancer2004

    • Author(s)
      Sakai, S., Soeda, H., Takahashi, N., et. al.
    • Organizer
      90th scientific assembly and annual meeting of RSNA
    • Place of Presentation
      Chicago
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Evaluation of image quality of temporal subtraction automatically produded images in PACS environment2004

    • Author(s)
      Sakai, S., Soeda, H, Furuya, A., et. al.
    • Organizer
      90th scientific assembly and annual meeting of RSNA
    • Place of Presentation
      Chicago
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 胸部単純X線診断をきわめる担当部分「1.ハードウエア」2007

    • Author(s)
      坂井 修二
    • Total Pages
      8
    • Publisher
      秀潤社
    • Related Report
      2007 Annual Research Report
  • [Book] 胸部単純X線診断をきわめる,「1.ハードウエア」2007

    • Author(s)
      坂井修二
    • Publisher
      秀潤社
    • Related Report
      2006 Annual Research Report
  • [Book] 胸部画像診断の勘ドコロ「腫瘤性病変のABC:非癌病変」2006

    • Author(s)
      坂井 修二
    • Publisher
      メジカルビュー社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary

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Published: 2004-04-01   Modified: 2016-04-21  

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