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Development of the optimal treatment schedule on high-dose-rate intracavitary brachytherapy for uterine cervical cancer

Research Project

Project/Area Number 16591214
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionUniversity of the Ryukyus

Principal Investigator

TOITA Takafumi  University of the Ryukyus, Faculty of Medicine, Associate professor, 医学部, 助教授 (30237036)

Co-Investigator(Kenkyū-buntansha) KAKINOHARA Yasumasa  University of the Ryukyus, Faculty of Medicine, Instructor, 医学部, 助手 (20185713)
KODAIRA Takeshi  Aichi Cancer Center, Radiation Oncology, Chief, 医長 (80303626)
TESHIMA Teruki  Osaka Univ., Medicine, Professor, 大学院・医学系研究科, 教授 (40136049)
MAEHAMA Toshiyuki  University of the Ryukyus, Faculty of Medicine, Associate professor, 医学部, 助教授 (50157153)
諸見里 秀彦  琉球大学, 医学部附属病院, 講師 (90244334)
Project Period (FY) 2004 – 2005
Project Status Completed (Fiscal Year 2005)
Budget Amount *help
¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 2005: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 2004: ¥1,800,000 (Direct Cost: ¥1,800,000)
KeywordsUterine cervical cancer / Radiotherapy / High-dose-rate intracavitary therapy / multi-institutional cooperative study
Research Abstract

1)Multi-institutional prospective clinical study of definitive radiotherapy using high-dose-rate intracavitary brachytherapy for stage I, II uterine cervical cancer is ongoing. Patient entry started from September 24, 2004. Target sample size was calculated to be 60. The estimated accrual phase of the study is 3 years. Administrative office is placed in the Department of Radiation Oncology, National Cancer Center Hospital. The data is managed in the Department of Medical Physics and Engineering, Osaka University.
2)This study was approved by IRB in 16 institutions. At the time of this writing (April 25, 2006), 30 patients have been entered into the study.
3)To keep the quality of radiotherapy utilized in this study, quality assurance (QA) and quality control (QC) committee was organized. The QA/QC committee performed the first QA review of radiotherapy on 15 patients treated on February 4, 2006.
4)We will continue the patient entry, data management, and QA review on radiotherapy. After closing the patient entry, data will be analyzed and the results will be submitted to the international journals.

Report

(3 results)
  • 2005 Annual Research Report   Final Research Report Summary
  • 2004 Annual Research Report
  • Research Products

    (25 results)

All 2005 2004 Other

All Journal Article (23 results) Book (2 results)

  • [Journal Article] Radiotherapy for uterine cervical cancer : results of the 1995-1997 patterns of care process survey in Japan.2005

    • Author(s)
      Toita T
    • Journal Title

      Jpn J Clin Oncol 35

      Pages: 139-148

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] Concurrent chemoradiotherapy using high-dose-rate intracavitary brachytherapy for uterine cervical cancer.2005

    • Author(s)
      Toita T
    • Journal Title

      Gynecol Oncol 96

      Pages: 665-670

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] 子宮頸癌放射線治療の標準化に向けて-特に線量に関する問題-.2005

    • Author(s)
      戸板孝文
    • Journal Title

      第3回婦人科悪性腫瘍化学療法研究機構総会記録集

      Pages: 11-15

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] 子宮頸癌の科学放射線治療の現状と展望2005

    • Author(s)
      戸板孝文
    • Journal Title

      臨床放射線 50

      Pages: 955-958

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 子宮頸部腺癌の放射線治療-適応と限界-2005

    • Author(s)
      戸板孝文
    • Journal Title

      日本婦人科腫瘍学会雑誌 23

      Pages: 436-438

    • NAID

      10020562046

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Patterns of Care Study in Japan2005

    • Author(s)
      Teshima T
    • Journal Title

      Jpn J Clin Oncol 35

      Pages: 497-506

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 子宮頸癌非手術(根治的放射線治療)症例におけるPatterns of Care Study (PCS) 95-97, 99-01調査の比較からみるevidenceの癌床への浸透2005

    • Author(s)
      古平毅
    • Journal Title

      癌の臨床 51

      Pages: 1037-1043

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Radiotherapy for uterine cervical cancer : results of the 1995-1997 patterns of care process survey in Japan.2005

    • Author(s)
      Toita T., et al.
    • Journal Title

      Jpn J Clin Oncol 35

      Pages: 139-148

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Concurrent chemoradiotherapy using high-dose-rate intracavitary brachytherapy for uterine cervical cancer.2005

    • Author(s)
      Toita T., et al.
    • Journal Title

      Gynecol Oncol 96

      Pages: 665-670

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Patterns of Care Study in Japan2005

    • Author(s)
      Teshima T.
    • Journal Title

      Jpn J Clin Oncol 35

      Pages: 497-506

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Chemoradiotherapy for uterine cervical cancer.2005

    • Author(s)
      Toita T., et al.
    • Journal Title

      Jpn J Clin Radiol 50

      Pages: 955-958

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Definitive radiotherapy for uterine cervical adenocarcinoma.2005

    • Author(s)
      Toita T., et al.
    • Journal Title

      J Jpn Soc Gynecol Oncol 23

      Pages: 436-438

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Patterns of radiotherapy practice for patients with carcinoma of the uterine cervix : clinical influence of evidence based medicine with comparison of two sueveys of Japanese patterns of care studies.2005

    • Author(s)
      Kodaira T, Toita T., et al.
    • Journal Title

      Jpn J Cancer Clin 51

      Pages: 1037-1043

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Standardization of radiotherapy for uterine cervical cancer.2005

    • Author(s)
      Toita T.
    • Journal Title

      Japanese Gynecologic Oncology Group 3rd Annual Meeting (suppl)

      Pages: 11-15

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 子宮頸癌の化学放射線治療の現状と展望2005

    • Author(s)
      戸板孝文
    • Journal Title

      臨床放射線 50

      Pages: 955-958

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 子宮頸部腺癌の放射線治療-適応と限界-.2005

    • Author(s)
      戸板孝文
    • Journal Title

      日本婦人科腫瘍学会雑誌 23

      Pages: 436-438

    • NAID

      10020562046

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 子宮頸癌に対するConcurrent Chemoradiation (CCRT):わが国における適応と問題点2004

    • Author(s)
      戸板孝文, 他
    • Journal Title

      癌の臨床 50・2

      Pages: 133-139

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 子宮頸癌における放射線治療の進歩2004

    • Author(s)
      戸板孝文, 他
    • Journal Title

      日本医事新報 4176

      Pages: 9-14

    • NAID

      40006180879

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 放射線腫瘍学の立場からみた化学放射線療法の問題点2004

    • Author(s)
      戸板孝文, 他
    • Journal Title

      日本婦人科腫瘍学会雑誌 22・4

      Pages: 343-347

    • NAID

      10012650360

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Concurrent chemoradiation for cervical cancer : What shoud we do next?

    • Author(s)
      Toita T
    • Journal Title

      Int J Clin Oncol (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Concurrent chemoradiation for cervical cancer : What should we do next?

    • Author(s)
      Toita T.
    • Journal Title

      Int J Clin Oncol (in press)

    • NAID

      10018768536

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Concurrent chemoradiotherapy using high-dose-rate intracavitary brachytherapy for uterine cervical cancer

    • Author(s)
      Takafumi Toita, et al.
    • Journal Title

      Gynecol Oncol (In press)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Radiotherapy for uterine cervical cancer : results of the 1995-1997 patterns of care process survey in Japan

    • Author(s)
      Takafumi Toita, et al.
    • Journal Title

      Jpn J Clin Oncol (In press)

    • Related Report
      2004 Annual Research Report
  • [Book] 放射線治療ガイドライン20042004

    • Author(s)
      戸板孝文
    • Total Pages
      4
    • Publisher
      日本放射線科専門医会・医会,日本放射線腫瘍学会,(社)日本医学放射線学会
    • Related Report
      2004 Annual Research Report
  • [Book] 放射線治療:専門医にきく最新の臨床(渋谷均, 笹井啓資, 小久保雅樹)2004

    • Author(s)
      戸板孝文
    • Total Pages
      6
    • Related Report
      2004 Annual Research Report

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Published: 2004-04-01   Modified: 2016-04-21  

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