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Improvement of athletic performances by mild hyperthermic training which included mild hyperthermia in sports training protocol.

Research Project

Project/Area Number 16591233
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionAichi Medical University

Principal Investigator

ITOH Youko  Aichi Medical Univ., Medical Dept., Assistant Professor, 医学部, 助教授 (60065597)

Co-Investigator(Kenkyū-buntansha) AIHARA Mariko  Aichi Medical Univ., Medical Dept., Lecturer, 医学部, 講師 (30184021)
Project Period (FY) 2004 – 2005
Project Status Completed (Fiscal Year 2005)
Budget Amount *help
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2005: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2004: ¥3,100,000 (Direct Cost: ¥3,100,000)
Keywordsmild hyperthermic training / HSP 70 (heat shock protein) / mile hyperthermia / hyperthermia / muscle pain / lactic acid / fatigue / NK activity (natural killer cells) / HSP70 / 予備加温 / 筋硬度 / 筋疲労 / 乳酸値
Research Abstract

It is well known that heat stress induces heat shock proteins (HSP 70) in cells. Also, mild hyperthermia (MH) induces HSP 70 that has a function as repairing the structure of proteins in stress-damaged cells and defense of cells against many kinds of stresses. We had reported the body protective effects of HSP 70 induced by MH as preconditioning using experimental animals, such as stress ulcer by water immersion, endotoxine shock, and kidney failure by reperfusion after renal-ischemia. This pre-heating by MH protected fatigue of leg muscle (Grant-in Aid for Scientific Research (C)). These results revealed that MH would improve performance of many sports and contribute for the sports world.
We propose mild hyperthermic training (MHT) which concluding MH in physical training. To confirm the our purpose, ten wrestling players were divided in two groups, MTH (mist sauna and far infrared ray device heating) and control group (just training) and they were examined the levels of athletic performances and measured HSP 70, lactic acid, NK activity at before (Test1) and 2 days after MHT (Test2). MHT inhibited the production of lactic acid after Test2 and increased the athletic performances, HSP 70 and NK-activity.
MH also protected muscle pain. Five healthy men were examined with muscle pain-examination (push-up ; 100times, squat ; 100times) with or without MH). Muscle pain score, muscle, solidity, CPK activity (inflammation of muscle), and Lactic acid were significantly decreased by MH.
Improvement of athletic performance by MH was confirmed by wrestling and cross-country players in winter Olympic. For the 21th century, we recommended MHT as a scientific training-using index of HSP 70. We can enjoy any sports ourselves by MH without muscle pain. We should extend mild hyperthermia (MH) and HSP 70 on the world.

Report

(3 results)
  • 2005 Annual Research Report   Final Research Report Summary
  • 2004 Annual Research Report
  • Research Products

    (24 results)

All 2006 2005 2004

All Journal Article (20 results) Book (4 results)

  • [Journal Article] Evaluation of heat shock protein induced in spa therapy with a simple thermal : preliminary experience.2005

    • Author(s)
      Kenji Tazawa, Youko Itoh, et al.
    • Journal Title

      Japanese Journal of Hyperthermic Oncology Vol.21, No.1

      Pages: 21-32

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] マウス局所および全身予備加温による生体防御 -口腔局所予備加温による舌熱傷の防御と全身予備加温による放射線障害の防御2005

    • Author(s)
      伊藤要子, 一本木真也, 中野雅則, 倉部輝久, 風岡宜暁, 石口恒男
    • Journal Title

      日本医学放射線学会雑誌 65巻3号

      Pages: 255-262

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Induction of HSP 70 in lymphocytes by whole body far-infrared hyperthermia.2005

    • Author(s)
      Youko Itoh, Kenji Tazawa, et al.
    • Journal Title

      Japanese Journal of Hyperthermic Oncology Vol.21, No.4

      Pages: 209-220

    • NAID

      10029676519

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 温熱療法(ハイパーサーミア) -癌の温熱療法とマイルド加温(HSP療法)-2005

    • Author(s)
      伊藤要子
    • Journal Title

      Medical Technology 33巻12号

      Pages: 1230-1232

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Evaluation oh heat shock protein 70 induced in spa therapy Woth a simple thermal : Preliminary experience.2005

    • Author(s)
      Kenji Tazawa, Youko Itoh, et al.
    • Journal Title

      Jpn.J.Hyperthermia Oncology Vol.21, No.1

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Bioprotection by local and whole-body preheating. -Bioprotection of damage to mice tongue from burning by local preheating of oral cavity and of radiation damage of small intestine from whole-body heating-2005

    • Author(s)
      Youko Itoh, Shinnya Ipponngi, et al.
    • Journal Title

      Nippon Acta Radiologica Vol.65, No.3

      Pages: 255-262

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Induction of HSP 70 in lymphocytes by whole body far-infrared hyperthermia.2005

    • Author(s)
      Youko Itoh, Kenji Tazawa, et al.
    • Journal Title

      Jpn.J.Hyperthermic Oncology Vol.21, No.4

      Pages: 209-220

    • NAID

      10029676519

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Hyperthermia -Hyperthermic oncology and mild hyperthermia (HSP therapy)-2005

    • Author(s)
      Youko Itoh
    • Journal Title

      Medical Technology Vol.33, No.12

      Pages: 1230-1232

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Evalution of Heat Shock Protein 70 induced in spa therapy with a simple thermal : Pureliminary experience.2005

    • Author(s)
      Kenji Tazawa, Youko Itoh, et al.
    • Journal Title

      Japanese Journal of Hyperthermic Oncology. Vol.21,No.1

      Pages: 21-32

    • Related Report
      2005 Annual Research Report
  • [Journal Article] マウス局所及び全身予備加温による生体防御効果 -口腔局所予備加温による舌熱傷の防御と全身予備加温による放射線障害の防御2005

    • Author(s)
      伊藤要子, 一本木真也, 中野雅則, 倉部輝久, 風岡宜暁, 石口恒男
    • Journal Title

      日本医学放射線学会雑誌 65巻,3号

      Pages: 255-262

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Induction of Hsp 70 in Lymphocytes by Whole Body Far-infrared Hyperthermia2005

    • Author(s)
      Youko Itoh, Kenji Tazawa, et al.
    • Journal Title

      Japanese Journal of Hyperthermic Oncology. Vol.21,No.4

    • NAID

      10029676519

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 温熱療法を取り入れたトレーニング(温熱トレーニング)による運動能力向上2005

    • Author(s)
      伊藤要子, 石口恒男
    • Journal Title

      日本医学放射線学会雑誌 Vol.65 臨時増刊号

    • Related Report
      2005 Annual Research Report
  • [Journal Article] マイルド予備加温による筋肉痛の防御2005

    • Author(s)
      伊藤要子, 中野雅則, 箭頭真理子, 小川耕平
    • Journal Title

      Jpn J.Hyperthemic Onoology. Vol.21,No.3

      Pages: 182-183

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 温熱トレーニング:加温を取り入れたトレーニング2005

    • Author(s)
      伊藤要子, 田澤賢次, 小川耕平.
    • Journal Title

      Jpn J.Hyperthermic Oncology. Vol.21,Supplement

      Pages: 92-92

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 熱ショック蛋白(HSP 70,HSP 60)2004

    • Author(s)
      伊藤要子, 菊池有子, 菊池有純
    • Journal Title

      日本臨床 -広範囲 血液・尿化学検査(1),A.蛋白関係 62巻増刊号11

      Pages: 285-287

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 全身加温による運動能力の向上 -温熱療法により誘導されるHSP 70を利用した温熱トレーニング-2004

    • Author(s)
      伊藤要子
    • Journal Title

      日温気物医誌 68巻1号

      Pages: 28-29

    • NAID

      10014053547

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Heat Shock Protein (HSP 70 and HSP 60)2004

    • Author(s)
      Youko Itoh, Yuko Kikuchi et al.
    • Journal Title

      Nippon rinsho Vol.62, Suppl.11

      Pages: 285-287

    • NAID

      40016874494

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Improvement of athletic performance by whole-body heating - Heating training with HSP 70 induced by heating -2004

    • Author(s)
      Youko Itoh
    • Journal Title

      J.Jpn.Association of physical Medicine, Balnelogy and climatology Vol.68, No.1

    • NAID

      10014053547

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] ミストサウナ, 遠赤外線加温による温熱トレーニング-HSP70と免疫力の増強-2004

    • Author(s)
      伊藤 要子 他
    • Journal Title

      Jpn J Hyperthermic Oncology Vol 20 Supple

      Pages: 72-72

    • Related Report
      2004 Annual Research Report
  • [Journal Article] マウスにおけるミストサウナでのマイルド連続加温によるストレス蛋白(HSP70)の誘導2004

    • Author(s)
      伊藤 要子 他
    • Journal Title

      日本医学放射線学会雑誌 Vol 64, No2臨時増刊号

    • Related Report
      2004 Annual Research Report
  • [Book] からだを温めるとなぜ病気が治るか2006

    • Author(s)
      石原結實, 伊藤要子
    • Total Pages
      192
    • Publisher
      ビジネス社
    • Related Report
      2005 Annual Research Report
  • [Book] HSPが病気を必ず治す2005

    • Author(s)
      伊藤 要子
    • Total Pages
      213
    • Publisher
      ビジネス社
    • Related Report
      2004 Annual Research Report
  • [Book] からだを温めると増えるHSPが病気を必ず治す2004

    • Author(s)
      伊藤要子
    • Publisher
      ビジネス社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Book] HSP would be sure to cure any sickness.2004

    • Author(s)
      Youko Itoh
    • Publisher
      Bijinesu Co.
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary

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Published: 2004-04-01   Modified: 2016-04-21  

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