• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Clinical basic research for the surgical treatment of the cervical carotid artery stenosis.

Research Project

Project/Area Number 16591433
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Cerebral neurosurgery
Research InstitutionTOYAMA UNIVERSITY (2005)
Toyama Medical and Pharmaceutical University (2004)

Principal Investigator

ENDO Shunro  Toyama University, Medicine, Neurosurgery, Professor, 医学部, 教授 (70125269)

Co-Investigator(Kenkyū-buntansha) 林 央周  富山医科薬科大学, 医学部, 助手 (50283073)
Project Period (FY) 2004 – 2005
Project Status Completed (Fiscal Year 2005)
Budget Amount *help
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2005: ¥1,600,000 (Direct Cost: ¥1,600,000)
Fiscal Year 2004: ¥1,800,000 (Direct Cost: ¥1,800,000)
Keywordsatheroma-thrombus / carotid artery stenosis / carotid artery occlusion / plateletaggregation / heparincofactor II / clamidia pneumonia / heparin / 脳高次機能 / 頸動脈分岐部 / 均整動脈 / 石灰化 / 内膜切除術 / ステント留置術 / 頚動脈分岐部
Research Abstract

The purpose of this study is to approach clinical-pathological feature of the carotid artery stenosis, ; especially about the arterial wall characteristics, and pathological meaning of heparin cofactor II and platelet aagregation,.
During 2 year research periods, the following four subjects were revealed as new evidence in this field, and important topics were reported in the journal.
1 Characteristic pathological findings of the arterial wall changes at the carotid bifurcation : relationship of the changes the elastic/muscular artery and limitation of the atheroma plaque extention.
These findings should reveal important information for surgical and endovascular treatment strategy.
2 Physiological and pathological mechanisms of heparin cofactor II.
3 Monitoring of platelet aggregation and heparin activation in patients undergoing neuroendovascular treatment or angiography.
Based on these studies, we continued research to investigate true pathological features of the carotid artery disease and to create the most adequate treatment selection and methods.

Report

(3 results)
  • 2005 Annual Research Report   Final Research Report Summary
  • 2004 Annual Research Report
  • Research Products

    (18 results)

All 2005 2004 Other

All Journal Article (17 results) Book (1 results)

  • [Journal Article] Adenovirus-mediated expression of heparin cofactorll inhibits thrombin-induced cellular responses in fibroblasts and vascular.......2005

    • Author(s)
      Hayakawa Y, Endo S, et al.
    • Journal Title

      Thrombosis Research 116

      Pages: 357-363

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 頸動脈アテロームプラークの伸展度と血管壁の性状に関する検討2005

    • Author(s)
      堀恵美子, 遠藤俊郎他
    • Journal Title

      脳卒中の外科 33

      Pages: 35-38

    • NAID

      110003739859

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] わが国における頸動脈狭窄病変の治療の現状分析及び診療ガイドライン作成に関する研究.2005

    • Author(s)
      遠藤俊郎, JCAS研究班
    • Journal Title

      平成15年度厚生省循環器病研究委託費による研究報告書

      Pages: 212-216

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Surgical anatomy of the cervical carotid artery for endarterectomy..2005

    • Author(s)
      Hayashi N, Endo S, et al.
    • Journal Title

      Neurol Med Chir(Tokyo) 46

      Pages: 25-30

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 頸部内頸動脈狭窄-CEAかステントか-2005

    • Author(s)
      遠藤俊郎, 他
    • Journal Title

      脳と神経 67

      Pages: 577-584

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Surgical anatomy of the cervical carotid artery for carotid endarterectomy2005

    • Author(s)
      Hayashi N, Hori E, Endo S et al.
    • Journal Title

      Neurol Med Chir (Tokyo) 45(1)

      Pages: 25-30

    • NAID

      110002283536

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Adenovirus-mediated expression of heparin cofactor II inhibits thrombin-induced cellular esponses in fibroblasts and vascular smooth muscle cells.2005

    • Author(s)
      Hayakawa Y, Endo S et al.
    • Journal Title

      Thrombosis Research 116

      Pages: 357-363

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 頸動脈アテロームプラークの伸展度と血管壁の性状に関する検討2005

    • Author(s)
      堀 恵美子, 遠藤俊郎ほか
    • Journal Title

      脳卒中の外科 33・2

      Pages: 35-38

    • NAID

      110003739859

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Adenovirus-mediated expression of heparin cofactor II inhibits thrombin-induced cellular response.2005

    • Author(s)
      Hayakawa Y, Endo S, et al.
    • Journal Title

      Thrombosis Research 116

      Pages: 357-363

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 頸部内頸動脈狭窄症2005

    • Author(s)
      遠藤俊郎ほか
    • Journal Title

      脳と神経 57・7

      Pages: 577-584

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Surgical anatomy of the cervical carotid artery for carotid endarterectomy2005

    • Author(s)
      Nakamasa Hayashi, Shunro Endo
    • Journal Title

      Neurol Med Chir(Tokyo) 45(1)

      Pages: 25-30

    • NAID

      110002283536

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Japan Carotid Althero- sclerosis Study : JCAS.2004

    • Author(s)
      Endo S, Kuwayama N, JCAS members
    • Journal Title

      Neurol Med Chir 44

      Pages: 215-217

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Japan Carotid Althero-sclerosis Study : JCAS.2004

    • Author(s)
      Endo S, Kuwayama N, Hayashi N, JCAS members
    • Journal Title

      Neurol Med Chir 44(4)

      Pages: 215-217

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] 脳外科手術適応と脳循環-内頚動脈剥離術-2004

    • Author(s)
      久保道也, 遠藤俊郎
    • Journal Title

      CLINICAL SCIENCE 22(4)

      Pages: 468-470

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Japan Carotid Atherosclerosis Study : JCAS2004

    • Author(s)
      Shunro Endo, et al.
    • Journal Title

      Neurol Med Chir(Tokyo) 44(2)

      Pages: 215-217

    • NAID

      110002277202

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 脳梗塞急性期の主幹動脈病変に対する外科治療-特に頚動脈内膜切除術の意義と限界-2004

    • Author(s)
      遠藤俊郎
    • Journal Title

      脳卒中 25(4)

      Pages: 419-424

    • Related Report
      2004 Annual Research Report
  • [Journal Article] A development of atheromatous plaque is restricted by characteristic arterial wall structure at the carotid bifurcation.

    • Author(s)
      Hori E, Hayashi N, Endo S
    • Journal Title

      Neurosurgery (in Japanese)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Book] 脳神経外科学大系3 基本手技2005

    • Author(s)
      遠藤俊郎, 林 央周
    • Related Report
      2005 Annual Research Report

URL: 

Published: 2004-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi