| Budget Amount *help |
¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 2006: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2005: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2004: ¥1,200,000 (Direct Cost: ¥1,200,000)
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| Research Abstract |
The 2-2 breathing during a marathon enables carbon dioxide elimination and oxygen uptake at a high metabolic rate over an extended period of time. Furthermore, from the evidence that the load by marathon does not cause the pulmonary physiological unbalance, this ventilation method can expect greater protective effects on the ventilator-induced lung injury in comparison with the small tidal volume ventilation method. So, the pulmonary oxygenation efficiency and pulmonary protective effects of the ventilation method using the marathoner's breath pattern (MBV) were studied in animal experiments using rabbits.
The time distribution (sec.) of one breath cycle is inspiration of 0.3, pause of 0.2, inspiration of 0.3, pause of 0.2, expiration of 0.3, pause of 0.2, and expiration of 0.5.
The following results were observed :
1) Although the MBV provides small-volume ventilation in both tidal volume and minute volume, there was not any problem in the efficiency of oxygen uptake and carbon dioxide elimination.
2) The airway pressure was kept low.
3) The effects were due to the gas redistribution phenomenon which occurred during the three pause periods.
4) This device can set PEEP (positive end-expiratory pressure) in two steps, so further effects can be observed.
5) In comparison with conventional ventilation method, the MBV method showed a lung protective effect by suppressing the wet-to-dry ratio.
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