| Project/Area Number |
16591953
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
補綴理工系歯学
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| Research Institution | HIROSHIMA UNIVERSITY |
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Principal Investigator |
MURATA Hiroshi Hiroshima University, Hospital, Assistant Professor, 病院, 講師 (40229993)
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| Co-Investigator(Kenkyū-buntansha) |
HAMADA Taizo Hiroshima University, Graduate School of Biomedical Sciences, Professor, 大学院・医歯学総合研究科, 教授 (50034244)
GUANG Hong Hiroshima University, Graduate School of Biomedical Sciences, Assistant, 大学院・医歯学総合研究科, 助手 (70363083)
SADAMORI Shinsuke Hiroshima University, Graduate School of Biomedical Sciences, Associate Professor, 大学院・医歯学総合研究科, 助教授 (40187167)
MAKIHIRA Seityo Hiroshima University, Hospita, Assistant, 病院・助手 (80304450)
二川 浩樹 広島大学, 病院・講師 (10228140)
西村 正宏 広島大学, 大学院・医歯薬学総合研究科, 助手 (00294570)
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| Project Period (FY) |
2004 – 2005
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| Project Status |
Completed (Fiscal Year 2005)
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| Budget Amount *help |
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2005: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 2004: ¥2,200,000 (Direct Cost: ¥2,200,000)
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| Keywords | Dry mouth / Soft denture liner / Denture adhesive / Saliva replacement gel / Viscoelasticity / Gelation |
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| Research Abstract |
Many elderly patients complaint of dry mouth and discomfort. It has been reported that 56.1% of the people above 65 years old aware of dry mouth. Thus, it is necessary to dissolve this problem as soon as possible. Clinically satisfied results are not obtained in the most of fabrication of dentures for the patients having dry mouth even if hard denture base resin and soft denture liner are applied, because of insufficient retention and stability, and/or masticatory pain. The purpose of this study was to develop a moisturized soft denture liner suitable for thee patients having dry mouth and severe absorbed residual ridge.
In 2004, the dynamic viscoelastic properties and bond strength to denture base resins of commercial denture adhesives and saliva replacement gels were determined. In the case of temporary soft lining materials, influence of molecular weight of polymer powders, plasticizer type, ethyl alcohol content and powder/liquid ratio on gelation characteristics (Journal of Dental Research, 2005).
In 2005, influence of above mentioned composition and structure on dynamic viscoelastic properties of temporary soft lining materials was evaluated. For the autopolymerized acrylic soft denture liners, the additional experiment concerning relationship between viscoelastic properties and type of monomer was conducted. The paper is being prepared now. On the other hand, relationship between masticatory function and viscoelastic properties of soft denture liners has been determined. It has been found that the application of a soft denture liner having viscoelastic properties to the complete denture leads to more marked improvement in masticatory function than that of a soft denture liner having elastic properties. On the basis of the above results, the composition and structure suitable for the moisturized soft denture liner for a patient having dry mouth were determined. At present, mechanical properties and functional effects of this material is evaluated.
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