| Budget Amount *help |
¥3,300,000 (Direct Cost: ¥3,300,000)
Fiscal Year 2006: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2005: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2004: ¥1,500,000 (Direct Cost: ¥1,500,000)
|
|---|
| Research Abstract |
From the aspects of neural activation of cerebral cortex accompanying mastication and swallowing, the effects of partial prosthodontic treatment was investigated with NIRS system (Hitachi, ETG 100) and following results were obtained ;
1. Using the principal component analysis for brain blood volume, muscle blood could be excluded from NIRS data, Hb mapping and topography were reconstructed with the changing of cerebral blood flow. Activation in the primary sensorimotor and post-parietal and supplementary motor cortices were indicated accompanying with the performance of matication and swallowing.
2. Cortical activation of primary sensorimotor cortex, and post-parietal and supplementary motor cortex during mastication were decreased by the injection of anesthesia into infra-alveolar nerve, therefore oral sensation can affect to the cortical sensorimotor function and sensory integration.
3. Masticatory loading and masticatory imagery activated the prefrontal cortex, and the focus of its activation was indicted in the bilateral dorsolateral prefrontal cortex areas.
4. Cortical activation of prefrontal cortex during mastication was decreased by the injection of anesthesia into infra-alveolar nerve, therefore prefrontal cortex is involved in perception of oral sensory and sensorimotor integration.
5. Oral dysesthesia indicated the hypofrontality in the prefrontal cortex comparing with healthy controls, it is therefore assumed that hypofrontality in mastication may reflect to the oral dysesthesia.
6. Concerning the effects of prosthodontic treatment to the cortical activation, wearing partial denture more activated the sensorimotor and prefrontal cortices during mastication.
It was assumed that the prosthodontic reconstruction of oral apparatus affects to the functional upgrading in the perception of oral sensory, the sensorimotor integration, and the masticatory motor planning and execution.
|
