Elucidation of widespread contamination status and bioaccumulation features of emerging persistent organic pollutants and assessment of their ecological effects

• Project/Area Number: 16H01784
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Environmental impact assessment
• Research Institution: Ehime University
• Principal Investigator: Tanabe Shinsuke 愛媛大学, 沿岸環境科学研究センター, 特別栄誉教授 (60116952)
• Co-Investigator(Kenkyū-buntansha): 国末 達也 愛媛大学, 沿岸環境科学研究センター, 教授 (90380287) ; 岩田 久人 愛媛大学, 沿岸環境科学研究センター, 教授 (10271652) ; 野見山 桂 愛媛大学, 沿岸環境科学研究センター, 准教授 (30512686)
• Project Period (FY): 2016-04-01 – 2019-03-31
• Project Status: Completed (Fiscal Year 2018)
• Budget Amount: ¥41,600,000 (Direct Cost: ¥32,000,000、Indirect Cost: ¥9,600,000); Fiscal Year 2018: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000); Fiscal Year 2017: ¥14,430,000 (Direct Cost: ¥11,100,000、Indirect Cost: ¥3,330,000); Fiscal Year 2016: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
• Keywords: 新規残留性有機汚染物質 / 生物蓄積 / 環境動態 / 生態影響 / リスク評価

Outline of Final Research Achievements

Widespread contamination status, bioaccumulation features, and temporal trends of persistent organic pollutants (POPs) and their candidate substances were determined. It was revealed that freshwater (brackish-water) fish, tilapia, collected from various areas in Asian countries have been widely exposed not only to POPs but also to a candidate substance, and in Japan, contamination of hexabromocyclododecanes (HBCDs) registered recently on the POPs convention was dominant and this new POP was bioaccumulated in various wild birds. When the temporal trends of POPs were analyzed in a pelagic whale species, HBCD levels increased significantly even in recent years. In addition, in vitro assay analysis indicated the presence of unknown aryl hydrocarbon receptor (AhR) aganists in the liver of wild avian species and instrumental analysis revealed the secondary formation of mixed halogenated dibenzofurans and dipheyl ethers in a developing country e-waste site.

Academic Significance and Societal Importance of the Research Achievements

アジア太平洋地域に生息する野生生物を対象に新規POPsとして知られるヘキサブロモシクロドデカン(HBCDs)やPOPs代替物質のモニタリング事例はきわめて少なく、本研究で得られた成果は、POPs条約の有効性評価や対象物質の追加について重要な基礎的知見となり得る。また、電気・電子機器廃棄物(e-waste)の不適切なリサイクル処理による化学物質汚染は、既知のPOPsだけでなく多様な有害化学物質の二次生成も関与していることを初めて突き止めた本研究成果は、現地での廃棄物処理に関わる規制の整備が急務であることに加え、資源循環と越境移動の適正化を目指す国際的な枠組みを制定する必要性を強調するものである。

Research Products

• [Int'l Joint Research] CSIR Water Research Institute(ガーナ)
• [Int'l Joint Research] Hanoi University of Science(ベトナム)
• [Int'l Joint Research] Brunel University(英国)
• [Int'l Joint Research] University of Aveiro(ポルトガル)
• [Int'l Joint Research] CSIR Water Research Institute(ガーナ)
• [Int'l Joint Research] Hanoi University of Science(ベトナム)
• [Int'l Joint Research] Brunel University(英国)
• [Int'l Joint Research] University of Aveiro/University of Beira Interior(ポルトガル)
• [Int'l Joint Research] University of Aveiro(Portugal)
• [Int'l Joint Research] Woods Hole(米国)
• [Int'l Joint Research] Bharathidasan University(India)
• [Int'l Joint Research] Hanoi University of Science(ベトナム)
• [Journal Article] Evaluation of a data-processing method for target and non-target screening using comprehensive two-dimensional gas chromatography coupled with high-resolution time-of-flight mass spectrometry for environmental samples (2019)
  • Author(s): Teruyo Ieda, Shunji Hashimoto, Tomohiko Isobe, Tatsuya Kunisue, Shinsuke Tanabe
  • Journal Title: Talanta Volume: 194 Pages: 461-468
  • DOI: 10.1016/j.talanta.2018.10.050
  • Peer Reviewed
• [Journal Article] Seasonal variation of atmospheric organochlorine pesticides and polybrominated diphenyl ethers in Parangipettai, Tamil Nadu, India: Implication for atmospheric transport (2019)
  • Author(s): Paromita Chakraborty, Gan Zhang, Jun Li, Pitchai Sampathkumar, Thangavel Balasubramanian, Kandasamy Kathiresan, Shin Takahashi, Annamalai Subramanian, Shinsuke Tanabe, Kevin C. Jones
  • Journal Title: Science of the Total Environment Volume: 649 Pages: 1653-1660
  • DOI: 10.1016/j.scitotenv.2018.07.414
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Occurrence of benzotriazole ultraviolet stabilizers (BUVSs) in human breast milk from three Asian countries (2019)
  • Author(s): Joon-Woo Kim, Kwang-Hyeon Chang, Maricar Prudente, Pham Hung Viet, Shin Takahashi, Shinsuke Tanabe, Tatsuya Kunisue, Tomohiko Isobe
  • Journal Title: Science of the Total Environment Volume: 655 Pages: 1081-1088
  • DOI: 10.1016/j.scitotenv.2018.11.298
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Exposure assessment of heavy metals in an e-waste processing area in northern Vietnam (2018)
  • Author(s): Tomoto Oguri, Go Suzuki, Hidenori Matsukami, Natsuyo Uchida, Nguyen Minh Tue, Le Huu Tuyen, Pham Hung Viet, Shin Takahashi, Shinsuke Tanabe, Hidetaka Takigami
  • Journal Title: Science of the Total Environment Volume: 621 Pages: 1115-1123
  • DOI: 10.1016/j.scitotenv.2017.10.115
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Alterations in urinary metabolomic profiles due to lead exposure from a lead?acid battery recycling site (2018)
  • Author(s): Eguchi Akifumi、Nomiyama Kei、Sakurai Kenichi、Kim Trang Pham Thi、Viet Pham Hung、Takahashi Shin、Iwata Hisato、Tanabe Shinsuke、Todaka Emiko、Mori Chisato
  • Journal Title: Environmental Pollution Volume: 242 Pages: 98-105
  • DOI: 10.1016/j.envpol.2018.06.071
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Cryptic lineage differentiation among Indo-Pacific bottlenose dolphins (Tursiops aduncus) in the northwest Indian Ocean (2018)
  • Author(s): Gray H.W.I.、Nishida S.、Welch A.J.、Moura A.E.、Tanabe S.、Kiani M.S.、Culloch R.、M?ller L.、Natoli A.、Ponnampalam L.S.、Minton G.、Gore M.、Collins T.、Willson A.、Baldwin R.、Hoelzel A.R.
  • Journal Title: Molecular Phylogenetics and Evolution Volume: 122 Pages: 1-14
  • DOI: 10.1016/j.ympev.2017.12.027
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Soil Pollution by Chlorobenzenes and Polychlorinated Biphenyls from an Electronic Waste Recycling Area in Northern Vietnam (2018)
  • Author(s): Nishimura, C., Suzuki, G., Matsukami, H., Agusa, T., Takaoka, M., Takahashi, S., Tue, N. M., Viet, P. H., Tanabe, S., Takigami, H., Fujimori, T.
  • Journal Title: International Journal of Environment and Pollution Volume: 63 Issue: 4 Pages: 283-297
  • DOI: 10.1504/ijep.2018.097863
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Occurrence, Profiles, and Toxic Equivalents of Chlorinated and Brominated Polycyclic Aromatic Hydrocarbons in E-waste Open Burning Soils (2017)
  • Author(s): Nishimura, C.; Horii, Y.; Tanaka, S.; Asante, K. A.; Ballesteros Jr., F. C.; Viet, P. H.; Itai, T.; Takigami, H.; Tanabe, S.; Fujimori, T.
  • Journal Title: Environmental Pollution Volume: 225 Pages: 252-260
  • DOI: 10.1016/j.envpol.2016.10.088
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Spatio-temporal trends of polybrominated dibenzo-p-dioxins and dibenzofurans in archived sediments from Tokyo Bay, Japan (2017)
  • Author(s): Goto Akitoshi, Tue Nguyen Minh, Someya Masayuki, Isobe Tomohiko, Takahashi Shin, Tanabe Shinsuke, Kunisue Tatsuya
  • Journal Title: Science of the Total Environment Volume: 599-600 Pages: 340-347
  • DOI: 10.1016/j.scitotenv.2017.04.166
  • Peer Reviewed
• [Journal Article] Species- and tissue-specific profiles of polybrominated diphenyl ethers and their hydroxylated and methoxylated derivatives in cats and dogs (2017)
  • Author(s): Kei Nomiyama , Kohki Takaguchi, Hazuki Mizukawa, Yasuko Nagano, Tomoko Oshihoi, Susumu Nakatsu, Tatsuya Kunisue, Shinsuke Tanabe
  • Journal Title: Environmental Science & Technology Volume: 51 Issue: 10 Pages: 5811-5819
  • DOI: 10.1021/acs.est.7b01262
  • Peer Reviewed / Open Access
• [Journal Article] Uridine Diphosphate-Glucuronosyltransferase (UGT) 2B Subfamily Interspecies Differences in Carnivores (2017)
  • Author(s): Kondo Takamitsu、Ikenaka Yoshinori、Nakayama Shouta M. M.、Kawai Yusuke K.、Mizukawa Hazuki、Mitani Yoko、Nomiyama Kei、Tanabe Shinsuke、Ishizuka Mayumi
  • Journal Title: Toxicological Sciences Volume: 158 Issue: 1 Pages: 90-100
  • DOI: 10.1093/toxsci/kfx072
  • Peer Reviewed / Open Access
• [Journal Article] Lead exposure in raptors from Japan and source identification using Pb stable isotope ratios (2017)
  • Author(s): Chihiro Ishii, Shouta M.M.Nakayama, Yoshinori Ikenaka, Hokuto Nakata, Keisuke Saito, Yukiko Watanabe, Hazuki Mizukawa, Shinsuke Tanabe, Kei Nomiyama, Terutake Hayashi, Mayumi Ishizuka
  • Journal Title: Chemosphere Volume: 186 Pages: 367-373
  • DOI: 10.1016/j.chemosphere.2017.07.143
  • NAID: 120006477493
  • Peer Reviewed / Open Access
• [Journal Article] Anthropogenic and naturally produced brominated phenols in pet blood and pet food in Japan (2017)
  • Author(s): Hazuki Mizukawa, Kei Nomiyama, Susumu Nakatsu, Miyuki Yamamoto, Mayumi Ishizuka, Yoshinori Ikenaka, Shouta M.M. Nakayama, Shinsuke Tanabe
  • Journal Title: Environmental Science & Technology Volume: 51 Issue: 19 Pages: 11354-11362
  • DOI: 10.1021/acs.est.7b01009
  • Peer Reviewed / Open Access
• [Journal Article] Occurrence of natural mixed halogenated dibenzo-p-dioxins: specific distribution and profiles in Mussels from Seto Inland Sea, Japan (2017)
  • Author(s): Goto Akitoshi, Tue Nguyen Minh, Someya Masayuki, Isobe Tomohiko, Takahashi Shin, Tanabe Shinsuke, Kunisue Tatsuya
  • Journal Title: Environmental Science & Technology Volume: 51 Issue: 20 Pages: 11771-11779
  • DOI: 10.1021/acs.est.7b03738
  • Peer Reviewed
• [Journal Article] Uptake and Metabolism of Human Pharmaceuticals by Fish: A Case Study with the Opioid Analgesic Tramadol (2017)
  • Author(s): Rumi Tanoue, Luigi Margiotta-Casaluci, Belinda Huerta, Tamsin J. Runnalls, Kei Nomiyama, Tatsuya Kunisue, Shinsuke Tanabe, John P. Sumpter
  • Journal Title: Environmental Science & Technology Volume: 51 Issue: 21 Pages: 12825-12835
  • DOI: 10.1021/acs.est.7b03441
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Cadmium intake in women from the University of Aveiro, Portugal ? A duplicate diet study (2017)
  • Author(s): Coelho Sonia D.、Maricoto Tiago、Pastorinho M. Ramiro、Itai Takaaki、Isobe Tomohiko、Kunisue Tatsuya、Tanabe Shinsuke、Sousa Ana C.A.、Nogueira Antonio J.A.
  • Journal Title: Journal of Geochemical Exploration Volume: 183 Pages: 187-190
  • DOI: 10.1016/j.gexplo.2017.02.003
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Levels of TBT and other selected organotin compounds in duplicate diet samples (2017)
  • Author(s): Sousa, A. C. A, Coelho, S. D., Pastorinho, M. R., Taborda-Barata. L., Nogueira, A. J. A., Isobe, T., Kunisue, T., Takahashi, S. and Tanabe, S.
  • Journal Title: Science of the Total Environment Volume: 574 Pages: 19-23
  • DOI: 10.1016/j.scitotenv.2016.09.037
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Concentrations of polybrominated diphenyl ethers and alternative flame retardants in surface soils and river sediments from an electronic waste-processing area in northern Vietnam, 2012-2014 (2017)
  • Author(s): Matsukami, H., Suzuki, G., Someya, M., Uchida, N., Tue, N. M., Tuyen, L. H., Viet, P. H., Takahashi, S., Tanabe, S. and Takigami, H.
  • Journal Title: Chemosphere Volume: 167 Pages: 291-209
  • DOI: 10.1016/j.chemosphere.2016.09.147
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Polybrominated diphenyl ethers (PBDEs) and their hydroxylated and methoxylated analogues in the blood of harbor, Dall's and finless porpoises from the Japanes e coastal waters (2016)
  • Author(s): Ochiai, M., Nomiyama, K., Isobe, T., Yamada, T. K., Tajima, Y., Matsuda, A., Shiozaki, A., Matsuishi, T., Amano, M., Iwata, H., Tanabe, S.
  • Journal Title: Marine Environmental Research Volume: 1136(16) Pages: 30260-30264
  • DOI: 10.1016/j.marenvres.2016.11.004
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Soil contamination by halogenated polycyclic aromatic hydrocarbons from open burning of e-waste in Agbogbloshie (Accra, Ghana) (2016)
  • Author(s): (2)Tue, N. M., Goto, A., Takahashi, S., Itai, T., Asante, K. A., Nomiyama, K., Tanabe, S., Kunisue, T.
  • Journal Title: Journal of Material Cycles and Waste Management Volume: 印刷中 Issue: 4 Pages: 1324-1332
  • DOI: 10.1007/s10163-016-0568-y
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] PCBs, PBDEs and dioxin-related compounds in floor dust from an informal end-of-life vehicle recycling site in northern Vietnam: contamination levels and implications for human exposure. (2016)
  • Author(s): (1)Takahashi, S., Tue, N.M., Takayanagi, C., Tuyen, L.H., Suzuki, G., Matsukami, H., Viet, P.H., Kunisue, T., Tanabe, S.
  • Journal Title: Journal of Material Cycles and Waste Management Volume: 印刷中 Issue: 4 Pages: 1333-1341
  • DOI: 10.1007/s10163-016-0571-3
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Brominated, chlorinated and phosphate organic contaminants in house dust from Portugal (2016)
  • Author(s): Coelho, S. D., Sousa, A. C. A., Isobe, T., Kim, J. W., Kunisue, T., Nogueira, A. J. A. and Tanabe, S.
  • Journal Title: Science of the Total Environment Volume: 569-570 Pages: 442-449
  • DOI: 10.1016/j.scitotenv.2016.06.137
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Occurrence of emerging flame retardants from e-waste recycling activities in the northern part of Vietnam (2016)
  • Author(s): Someya, M., Suzuki, G., Ionas, A. C., Tue, N. M., Xu, F., Matsukami, H., Covaci, A., Tuyen, L. H., Viet, P. H., Takahashi, S., Tanabe, S. and Takigami, H.
  • Journal Title: Emerging Contaminants Volume: 2 Issue: 2 Pages: 58-65
  • DOI: 10.1016/j.emcon.2015.10.002
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Analysis of monomeric and oligomeric organophosphorus flame retardants in fish muscle tissues using liquid chromatography-electrospray ionization tandem mass spectrometry: Application to Nile tilapia (Oreochromis niloticus) from an e-waste processing area in northern Vietnam (2016)
  • Author(s): Matsukami, H., Suzuki, G., Tue, N. M., Tuyen, L. H., Viet, P. H., Takahashi, S., Tanabe, S. and Takigami, H.
  • Journal Title: Emerging Contaminants Volume: 2 Issue: 2 Pages: 89-97
  • DOI: 10.1016/j.emcon.2016.03.004
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Comprehensive evaluation of dioxins and dioxin-like compounds in surface soils and river sediments from e-waste-processing sites in a village in northern Vietnam: Heading towards the environmentally sound management of e-waste (2016)
  • Author(s): Suzuki, G., Someya, M., Matsukami, H., Tue, N. M., Uchida, N., Tuyen, L. H., Viet, P. H., Takahashi, S., Tanabe, S., Brouwer, A. and Takigami, H.
  • Journal Title: Emerging Contaminants Volume: 2 Issue: 2 Pages: 98-108
  • DOI: 10.1016/j.emcon.2016.03.001
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Brominated flame retardants and organochlorine compounds in duplicate diet samples from a Portuguese academic community (2016)
  • Author(s): Coelho, S. D., Sousa, A. C. A., Isobe, T., Kunisue, T., Nogueira, A. J. A. and Tanabe, S.
  • Journal Title: Chemosphere Volume: 160 Pages: 89-94
  • DOI: 10.1016/j.chemosphere.2016.06.038
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Edward D. Goldburg’s proposal of the “the Mussel Watch”: Reflections after 40 years (2016)
  • Author(s): Farrington, J. W., Tripp, B. W., Tanabe, S., Subramanian, An., Sericano, J. L., Wade, T. L. and Knap, A. H.
  • Journal Title: Marine Pollution Bulletin Volume: 110 Issue: 1 Pages: 501-510
  • DOI: 10.1016/j.marpolbul.2016.05.074
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Lead contamination in surface soil on roads from used lead-acid battery recycling in Northern Vietnam (2016)
  • Author(s): Fujimori, T., Eguchi, A., Agusa, T., Tue, N. M., Suzuki, G., Takahashi, S., Viet, P. H., Tanabe, S. and Takigami, H.
  • Journal Title: Journal of Material Cycles and Waste Management Volume: 18(4) Issue: 4 Pages: 599-607
  • DOI: 10.1007/s10163-016-0527-7
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Lead in duplicate diet samples from an academic community (2016)
  • Author(s): Coelho, S. D., Pastorinho, M. R., Itai, T., Isobe, T., Kunisue, T., Nogueira, A. J. A., Tanabe, S. and Sousa, A. C. A.
  • Journal Title: Science of the Total Environment Volume: 573 Pages: 603-607
  • DOI: 10.1016/j.scitotenv.2016.08.133
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Contamination Status of PCBs and Organochlorine Pesticides in the Okinawa Island, Japan: Utilization of Small Indian Mongoose (<i>Herpestes auropunctatus</i>) as a Bioindicator (2016)
  • Author(s): Tashiro, Y., Goto, A., Kunisue, T., Kurahashi, T. and Tanabe, S.
  • Journal Title: Journal of Environmental Chemistry Volume: 26 Issue: 3 Pages: 115-122
  • DOI: 10.5985/jec.26.115
  • NAID: 130005465067
  • ISSN: 0917-2408, 1882-5818
  • Peer Reviewed
• [Journal Article] Halogenated Polycyclic Aromatic Hydrocarbons in Soil and River Sediment from E-waste Recycling Sites in Vietnam (2016)
  • Author(s): Wang, Q., Miyake, Y., Amagi, T., Matsukami, H., Tue, N. M., Takahashi, S., Tanabe, S., Viet, P. H. and Takigami, H.
  • Journal Title: Journal of Water and Environment Technology Volume: 14 Issue: 3 Pages: 166-176
  • DOI: 10.2965/jwet.15-053
  • NAID: 130005156734
  • ISSN: 1348-2165
  • Peer Reviewed / Int'l Joint Research
• [Presentation] Thermally produced derivatives of halogenated flame retardants in soils from e-waste dismantling and burning areas (2018)
  • Author(s): Tue, N. M., Matsushita, T., Goto, A., Itai, T., Asante, K. A., Tanabe, S. and Kunisue, T.
  • Organizer: Brominated Flame Retardant Workshop 2018 (BFR 2018)
  • Int'l Joint Research
• [Presentation] AhR agonists in Japanese wild birds evaluated by chemical analysis and bioassays (2018)
  • Author(s): Kasuya, M., Tue, N. M., Goto, A., Tanabe, S. and Kunisue, T.
  • Organizer: 38th International Symposium on Halogenated Persistent Organic Pollutants (DIOXIN 2018)
  • Int'l Joint Research
• [Presentation] Temporal trend analyses of POPs in three toothed whale species stranded along the Japanese coastal waters: importance of samples and data stored in es-BANK and ChemTHEATRE (2018)
  • Author(s): Kunisue, T., Egashira, K., Isobe, T., Nakayama, K., Matsuishi, T., Tajima, Y., Yamada, T. K. and Tanabe, S.
  • Organizer: 38th International Symposium on Halogenated Persistent Organic Pollutants (DIOXIN 2018)
  • Int'l Joint Research
• [Presentation] Contamination status and global comparison of organohalogen compounds and their related compounds in the pet cats in Thailand (2018)
  • Author(s): Shimasaki, M., Nomiyama, K., Mizukawa, H., Saengtienchai, A., Ngamchirttakul, A., Pencharee, D., Ikenaka, Y., Nakayama, S., Kunisue, T. and Tanabe, S.
  • Organizer: 38th International Symposium on Halogenated Persistent Organic Pollutants (DIOXIN 2018)
  • Int'l Joint Research
• [Presentation] Coastal monitoring of organohalogen compounds using oysters from Okinawa island, Japan (2018)
  • Author(s): Mukai, Y., Goto, A., Tashiro, Y., Tanabe, S. and Kunisue T.
  • Organizer: 38th International Symposium on Halogenated Persistent Organic Pollutants (DIOXIN 2018)
  • Int'l Joint Research
• [Presentation] Pilot study on the toxicological assessment of organohalogen compounds in pet cat (Felis catus) serum using metabolomics approach (2018)
  • Author(s): Nomiyama, K., Eguchi, A., Mizukawa, H., Yamamoto, Y., Nishikawa, H., Takiguchi, M., Nakayama, S., Ikenaka, Y., Isizuka, M. and Tanabe, S.
  • Organizer: 38th International Symposium on Halogenated Persistent Organic Pollutants (DIOXIN 2018)
  • Int'l Joint Research
• [Presentation] Effects of PCB exposure on thyroid hormone levels in serum of dogs and cats (2018)
  • Author(s): Takaguchi, K., Nishikawa, H., Mizukawa, H., Tanoue, R., Yokoyama, N., Ichii, O., Takiguchi, M., Nakayama, S. M., Ikenaka, Y., Kunisue, T., Ishizuka, M., Tanabe, S., Iwata, H. and Nomiyama, K.
  • Organizer: SETAC North America 39th Annual Meeting
  • Int'l Joint Research
• [Presentation] ネコのin vivo BDE209 長期曝露試験による体内動態の解明および甲状腺ホルモンへの影響評 (2018)
  • Author(s): 田中啓介・野見山 桂・水川葉月・高口倖暉・田上瑠美・横山 望・市居 修・滝口満喜・中山翔太・池中良徳・石塚真由美・国末達也・田辺信介
  • Organizer: 第27回環境化学討論会
• [Presentation] タイ王国におけるペットネコ血清およびペットフード中有機ハロゲン化合物と類縁化合物の汚染実態 (2018)
  • Author(s): 島﨑真琴・野見山 桂・水川葉月・Saengtienchai, A.・Ngamchirttakul, A.・Pencharee, D.・星野光希・山本恭央・高口倖暉1・石塚真由美・池中良徳・中山翔太・国末達也・田辺信介
  • Organizer: 第27回環境化学討論会
• [Presentation] CALUXによる日本の野生鳥類に残留するダイオキシン類縁化合物の活性評価 (2018)
  • Author(s): 粕谷満知子・Tue, N. M.・後藤 哲智・田辺 信介・国末達也
  • Organizer: 第27回環境化学討論会
• [Presentation] 血清中メタボローム解析によるペットネコ（Felis catus）の有機ハロゲン化合物毒性影響評価 (2018)
  • Author(s): 野見山 桂・江口哲史・西川博之・水川葉月・山本恭央・滝口満喜・中山翔太・池中良徳・石塚真由美・田辺信介
  • Organizer: 第27回環境化学討論会
• [Presentation] 瀬戸内海のイガイに蓄積するハロゲン化アルカロイドの構造解析 (2018)
  • Author(s): 後藤哲智・Tue, N. M.・田辺信介・国末達也
  • Organizer: 第27回環境化学討論会
• [Presentation] 沖縄県沿岸のカキを用いた有機ハロゲン化合物の汚染モニタリング (2018)
  • Author(s): 向井幸乃・後藤哲智・田代 豊・田辺信介・国末達也
  • Organizer: 第27回環境化学討論会
• [Presentation] GC×GC-ToFMS による天然有機ハロゲン化合物の網羅的スクリーニング (2018)
  • Author(s): 後藤哲智・Tue, N. M.・田辺信介・国末達也
  • Organizer: 第66回質量分析総合討論会
• [Presentation] 鯨類の脂皮に蓄積する有機ハロゲン化合物のプロファイル解析 (2018)
  • Author(s): 須之内朋哉・後藤哲智・落合真理・田島木綿子・山田 格・田辺信介・国末達也
  • Organizer: 日本セトロジー研究会第29回福岡大会
• [Presentation] 瀬戸内海および大村湾のスナメリにおける有機ハロゲン化合物汚染と経年変化 (2018)
  • Author(s): 川邊 陸・後藤哲智・落合真理・山田 格・田島木綿子・天野雅男・田辺信介・国末達也
  • Organizer: 日本セトロジー研究会第29回福岡大会
• [Presentation] ポリ塩化ビフェニル曝露によるイヌ・ネコの甲状腺ホルモン恒常性への影響 (2018)
  • Author(s): 高口倖暉・野見山 桂・西川博之・水川葉月・田上瑠美・草木桃子・横山 望・市居 修・滝口満喜・中山翔太・池中良徳・石塚真由美・岩田久人・国末達也・田辺信介
  • Organizer: 第45回日本毒性学会学術年会
• [Presentation] インドe-waste処理場の作業環境における難燃剤汚染と労働者への曝露評価 (2018)
  • Author(s): 小川雄平・Tue, N. M.・後藤哲智・Subramanian, An.・Parthasarathy, P.・Bulbule, K. A.・田辺信介・国末達也
  • Organizer: 第29回廃棄物資源循環学会研究発表会
• [Presentation] 射撃場起源の微量元素汚染拡散の実態解明 (2017)
  • Author(s): 佐々木 眞・田辺信介・国末達也・岩淵博之・宮脇隼輔・寳來 佐和子
  • Organizer: 第26回環境化学討論会
• [Presentation] 日野川水系上流部における微量元素の起源探索およびタカハヤ (Phoxinus oxycephalus jouyi) を用いた初期曝露試験による毒性影響評価 (2017)
  • Author(s): 森木 翼・吉田博一・田辺信介・国末達也・杉山晶彦・寳來 佐和子
  • Organizer: 第26回環境化学討論会
• [Presentation] リン酸エステル系難燃剤による野生鳥類の汚染 －分析法の開発と種間比較－ (2017)
  • Author(s): 麓 光央・後藤哲智・Tue, N. M.・中津 賞・野見山 桂・田辺信介・国末達也
  • Organizer: 第26回環境化学討論会
• [Presentation] 日本沿岸に座礁したハクジラ類における有機ハロゲン化合物汚染の経年変化 (2017)
  • Author(s): 江頭佳奈・落合 真・Tue, N. M.・松田純佳・松石 隆・田島 木綿子・山田 格・磯部友彦・田辺信介・国末達也
  • Organizer: 第26回環境化学討論会
• [Presentation] 日本に棲息する野生生物のダイオキシン類汚染：化学分析とin vitroバイオアッセイの統合手法による毒性同定評価 (2017)
  • Author(s): 粕谷 満知子・Tue, N. M.・後藤哲智・田辺信介・国末達也
  • Organizer: 第26回環境化学討論会
• [Presentation] 医薬品類およびパーソナルケア製品由来物質（PPCPs）によるアジア途上国の水環境汚染の実態解明と魚類への移行/残留性評価 (2017)
  • Author(s): 野崎一茶・田上瑠美・野見山 桂・Annamalai，A.・Bulbule，K. A.・Parthasarathy, P.・Viet, P. H.・Tuyen，L. H.・Sudaryanto, A.・磯部友彦・国末達也・田辺信介
  • Organizer: 第26回環境化学討論会
• [Presentation] 底質中環境汚染物質のノンターゲット分析－試料の網羅的解析と精密質量スペクトルデータベースの構築－ (2017)
  • Author(s): 家田曜世・橋本俊次・磯部友彦・高澤嘉一・田邊 潔・国末達也・田辺信介
  • Organizer: 第26回環境化学討論会
• [Presentation] Hormone disrupting activities and causative compounds in river water from Asian developing countries. (2017)
  • Author(s): Tue, N. M., Matsukami, H., Tuyen, L. H., Takahashi, S., Suzuki, G., Viet, P. H., Subramanian, A., Tanabe, S. and Kunisue, T.
  • Organizer: 19th International Symposium on Pollutant Responses in Marine Organisms (PRIMO19)
  • Int'l Joint Research
• [Presentation] Spatio-temporal trend of contamination by persistent organic pollutants in deep-sea ecosystems around Japan. (2017)
  • Author(s): Takahashi, S., Tanikawa, M., Ramu, K., Imagawa, S., Saruwatari, T., Kubodera, T. and Tanabe, S.
  • Organizer: 19th International Symposium on Pollutant Responses in Marine Organisms (PRIMO19)
  • Int'l Joint Research
• [Presentation] In vitro bioassay and chemical analysis of dioxins in wild animals from Japan. (2017)
  • Author(s): Kasuya, M., Tue, N. M., Goto, A., Tanabe, S. and Kunisue, T.
  • Organizer: 19th International Symposium on Pollutant Responses in Marine Organisms (PRIMO19)
  • Int'l Joint Research
• [Presentation] Temporal trends of organohalogen compounds in toothed whales stranded at Japanese coastal waters. (2017)
  • Author(s): Egashira, K., Ochiai, M., Tue, N. M., Matsuda, A., Matsuishi, T., Tajima, Y., Yamada, T. K., Isobe, T., Tanabe, S. and Kunisue, T.
  • Organizer: 19th International Symposium on Pollutant Responses in Marine Organisms (PRIMO19)
  • Int'l Joint Research
• [Presentation] Organophosphate flame retardants in wild birds - development of analytical methods and interspecies comparison. (2017)
  • Author(s): Fumoto, M., Tue, N. M., Goto, A., Nakatsu, S., Nomiyama, K., Tanabe, S. and Kunisue, T.
  • Organizer: 19th International Symposium on Pollutant Responses in Marine Organisms (PRIMO19)
  • Int'l Joint Research
• [Presentation] Origin of brominated dioxins in marine algae: Anthropogenic contaminants or natural compounds? (2017)
  • Author(s): Goto A., Tue, N. M., Tanabe, S. and Kunisue, T.
  • Organizer: 19th International Symposium on Pollutant Responses in Marine Organisms (PRIMO19)
  • Int'l Joint Research
• [Presentation] PCDD/Fs, DL-PCBs and PBDEs in the duplicate soils of Tiruchirappalli town, South India. (2017)
  • Author(s): Subramanian, A., Ramaswamy, B. R., Matsushita, T., Krishnamoorthi, V., Kunisue, T. and Tanabe, S.
  • Organizer: 19th International Symposium on Pollutant Responses in Marine Organisms (PRIMO19)
  • Int'l Joint Research
• [Presentation] Pharmaceutical and personal care products in freshwater fish from Asian developing countries. (2017)
  • Author(s): Nozaki, K., Tanoue, R., Nomiyama, K., Subramanian, A., Bulbule, K. A., Parhasarathy, P., Viet, P. H., Tuyen, L. H., Sudaryanto, A., Isobe, T., Kunisue, T. and Tanabe, S.
  • Organizer: 19th International Symposium on Pollutant Responses in Marine Organisms (PRIMO19)
  • Int'l Joint Research
• [Presentation] Organohalogen compounds in serum of e-waste recycling workers in India. (2017)
  • Author(s): Ogawa, Y., Tue, N. M., Goto, A., Subramanian, A., Parthasarathy, P., Bulbule, K. A., Tanabe, S. and Kunisue, T.
  • Organizer: 19th International Symposium on Pollutant Responses in Marine Organisms (PRIMO19)
  • Int'l Joint Research
• [Presentation] Temporal trends of brominated flame retardants and organochlorines in melon-headed whales stranded along the Japanese coastal waters: Utilization of samples and data stored in es-BANK and ChemTHEATRE. (2017)
  • Author(s): Kunisue, T., Egashira, K., Isobe, T., Nakayama, K., Tajima, Y., Yamada, T. K. and Tanabe, S.
  • Organizer: 37th International Symposium on Halogenated Persistent Organic Pollutants (DIOXIN 2017)
  • Int'l Joint Research
• [Presentation] Occurrence and potential sources of brominated/chlorinated dibenzo-p-dioxins in mussels from the Seto Inland Sea, Japan. (2017)
  • Author(s): Goto, A., Tue, N. M., Someya, M., Isobe, T., Takahashi, S., Tanabe, S. and Kunisue, T.
  • Organizer: 37th International Symposium on Halogenated Persistent Organic Pollutants (DIOXIN 2017)
  • Int'l Joint Research
• [Presentation] Distribution and composition of brominated/chlorinated dioxins and diphenyl ethers in surface soil from Agbogbloshie, Ghana. (2017)
  • Author(s): Tue, N. M., Matsushita, T., Goto, A., Itai, T., Asante, K. A., Tanabe, S. and Kunisue, T.
  • Organizer: 37th International Symposium on Halogenated Persistent Organic Pollutants (DIOXIN 2017)
  • Int'l Joint Research
• [Presentation] インド・ベンガルールに存在するe-wasteリサイクル処理施設労働者の臭素系難燃剤汚染―作業環境改善による血中レベルの低減― (2017)
  • Author(s): 小川雄平・Tue, N. M.・後藤哲智・Subramanian, An.・Parthasarathy, P.・Bulbule, K. A.・田辺信介・国末達也
  • Organizer: 第28回廃棄物資源循環学会研究発表会
• [Presentation] Persistent organic pollutants (POPs) in dolphin species: Species and tissue-specific accumulation. (2017)
  • Author(s): Ochiai, M., Isobe, T., Tajima, Y., Nomiyama, K., Kunisue, T., Iwata, H. and Tanabe, S.
  • Organizer: 10th International Meeting of Asian Society of Conservation Medicine
  • Int'l Joint Research
• [Presentation] PCBs and BFRs in dust and human blood samples from end of life vehicle (ELV) recycling sites in northern Vietnam: comparison with E-waste recycling sites (2016)
  • Author(s): Takahashi, S., Nose, K., Miyai, R., Takayanagi, C., Tue, N. M., Tuyen, L. H., Viet, P. H., Tanabe, H.
  • Organizer: The 9th International PCB Workshop
  • Place of Presentation: 神戸国際会議場（兵庫県・神戸市）
  • Year and Date: 2016-10-09
  • Int'l Joint Research
• [Presentation] 有機ハロゲン化合物によるガーナe-waste処理場の土壌汚染 - 不適切な処理にともなう有害化学物質の環境放出 - (2016)
  • Author(s): 松下尚史・後藤哲智・Tue, N. M.・板井啓明・Asante, K. A.・田辺信介・国末達也
  • Organizer: 第27回廃棄物資源循環学会研究発表会
  • Place of Presentation: 和歌山大学（和歌山県・和歌山市）
  • Year and Date: 2016-09-27
• [Presentation] Screening of organohalogen compounds accumulated in the liver of wild bird specimens using GCxGC-ToFMS (2016)
  • Author(s): Tue, N. M., Goto, A., Fumoto, M., Nakatsu, S., Tanabe, S., Kunisue, T.
  • Organizer: 36th International Symposium on Halogenated Persistent Organic Pollutants
  • Place of Presentation: Firenze, Italy
  • Year and Date: 2016-08-28
  • Int'l Joint Research
• [Presentation] Contamination levels and temporal trend of flame retardants in human breast milk from Japan (2016)
  • Author(s): Kunisue, T., Nishimoto, K., Kim, J., Isobe, T., Tanabe, S.
  • Organizer: 36th International Symposium on Halogenated Persistent Organic Pollutants
  • Place of Presentation: Firenze, Italy
  • Year and Date: 2016-08-28
  • Int'l Joint Research
• [Presentation] Influence of heavy metals on formation of Dioxin-related compounds in e-waste open dumping soil (2016)
  • Author(s): Fujimori, T., Itai, T., Goto, A., Asante, K., Otsuka, M., Takahashi, S., Tanabe, S.
  • Organizer: 36th International Symposium on Halogenated Persistent Organic Pollutants
  • Place of Presentation: Firenze, Italy
  • Year and Date: 2016-08-28
  • Int'l Joint Research
• [Presentation] Levels of polybrominated diphenyl ether (PBDE) and NON-PBDE flame retardants in chicken and fish samples from an electronic waste processing area in Northern Vietnam (2016)
  • Author(s): Matsukami, H., Suzuki, G., Tao, F., Tue, N. M., Tuyen, L. H., Viet, P. H., Takahashi, S., Tanabe, S., Harrad, S., Takigami, H.
  • Organizer: 36th International Symposium on Halogenated Persistent Organic Pollutants
  • Place of Presentation: Firenze, Italy
  • Year and Date: 2016-08-28
  • Int'l Joint Research
• [Presentation] Concentration profiles of halogenated polycyclic aromatic hydrocarbons in soil and river sediment from recycling sites in Vietnam (2016)
  • Author(s): Miyake, Y., Wang, Q., Amagai, T., Suzuki, G., Matsukami, H., Tue, N. M., Takahashi, S., Tanabe, S.
  • Organizer: 36th International Symposium on Halogenated Persistent Organic Pollutants
  • Place of Presentation: Firenze, Italy
  • Year and Date: 2016-08-28
  • Int'l Joint Research
• [Presentation] 茨城県に集団座礁したカズハゴンドウ（Peponocephala electra）に残留するPCBs, OH-PCBs の脳内負荷量と母子間移行 (2016)
  • Author(s): 落合真理・野見山 桂・磯部友彦・山田 格・田島 木綿子・岩田久人・国末達也・田辺信介
  • Organizer: 日本セトロジー研究会第27回大会
  • Place of Presentation: 長岡市寺泊文化センター（新潟県・長岡市）
  • Year and Date: 2016-06-25
• [Presentation] 北海道沿岸に座礁した鯨類における有機ハロゲン化合物の蓄積特性 (2016)
  • Author(s): 江頭佳奈・磯部友彦・落合真理・松石 隆・松田純佳・山田 格・田島 木綿子・田辺信介・国末達也
  • Organizer: 日本セトロジー研究会第27回大会
  • Place of Presentation: 長岡市寺泊文化センター（新潟県・長岡市）
  • Year and Date: 2016-06-25
• [Presentation] 日本近海沿岸に漂着した鯨類に残留する生物蓄積性有機ハロゲン化合物の網羅分析 (2016)
  • Author(s): 元木一貴・野見山 桂・後藤哲智・落合真理・江頭佳奈・田島 木綿子・山田 格・磯部友彦・国末達也・田辺信介
  • Organizer: 第25回環境化学討論会
  • Place of Presentation: 新潟コンベンションセンター（新潟県・新潟市）
  • Year and Date: 2016-06-08
• [Presentation] ガーナe-waste 処理場の土壌に残留する有機ハロゲン化合物の網羅分析 (2016)
  • Author(s): 松下尚史・後藤哲智・Tue, N. M.・板井啓明・Asante, K. A.・田辺信介・国末達也
  • Organizer: 第25回環境化学討論会
  • Place of Presentation: 新潟コンベンションセンター（新潟県・新潟市）
  • Year and Date: 2016-06-08
• [Presentation] 野生鳥類におけるPOPs および代替難燃剤の汚染実態と蓄積特性 (2016)
  • Author(s): 麓 光央・後藤哲智・Tue, N. M.・中津 賞・野見山 桂・田辺信介・国末達也
  • Organizer: 第25回環境化学討論会
  • Place of Presentation: 新潟コンベンションセンター（新潟県・新潟市）
  • Year and Date: 2016-06-08
• [Presentation] 沖縄島におけるハブとマングース体内の有機塩素化合物濃度分布 (2016)
  • Author(s): 田代 豊・国末達也・後藤哲智・田辺信介
  • Organizer: 第25回環境化学討論会
  • Place of Presentation: 新潟コンベンションセンター（新潟県・新潟市）
  • Year and Date: 2016-06-08
• [Presentation] ベトナム北部の電気電子機器廃棄物（e-waste）の処理地域における鶏および養殖魚中ポリ臭素化ジフェニルエーテル類等難燃剤 (2016)
  • Author(s): 松神秀徳・鈴木 剛・宇智田 奈津代・Tue, N. M.・Tuyen, L. H.・小栗朋子・Viet，P. H.・高橋 真・田辺信介・滝上英孝
  • Organizer: 第25回環境化学討論会
  • Place of Presentation: 新潟コンベンションセンター（新潟県・新潟市）
  • Year and Date: 2016-06-08
• [Presentation] 電気電子機器廃棄物（e-waste）の環境上適切な管理にむけて～ベトナム北部e-waste リサイクル村での3カ年のフィールド調査概要について～ (2016)
  • Author(s): 鈴木 剛・松神秀徳・宇智田 奈津代・Tue, N. M.・Tuyen, L. H.・大木亨祐・Viet, P. H.・高橋 真・田辺信介・滝上 英孝
  • Organizer: 第25回環境化学討論会
  • Place of Presentation: 新潟コンベンションセンター（新潟県・新潟市）
  • Year and Date: 2016-06-08