| Budget Amount *help |
¥45,630,000 (Direct Cost: ¥35,100,000、Indirect Cost: ¥10,530,000)
Fiscal Year 2018: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000)
Fiscal Year 2017: ¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000)
Fiscal Year 2016: ¥21,450,000 (Direct Cost: ¥16,500,000、Indirect Cost: ¥4,950,000)
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| Outline of Final Research Achievements |
In this research, we have successfully demonstrated preparations and physical analyses of novel molecular assemblies composed of amphiphilic block polypeptides and cyclic peptides. The structures of the molecular assemblies are categorized from primary to quaternary structures. Primary structure: single morphology including sheet, tube, and vesicle etc. Secondary structure: chimera morphology like a round-bottom-flask shape and a test-tube shape. Tertiary structure: single morphology showing a hierarchical structure like an unsymmetric vesicle and a phase-separated tube. Quaternary structure: Ordered assembling of molecular assemblies like a bundle of tubes. Strategies for the molecular designs for these hierarchical molecular assemblies have been demonstrated in this research.
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