| Budget Amount *help |
¥26,910,000 (Direct Cost: ¥20,700,000、Indirect Cost: ¥6,210,000)
Fiscal Year 2018: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000)
Fiscal Year 2017: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000)
Fiscal Year 2016: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
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| Outline of Final Research Achievements |
Magnetotactic bacteria synthesize iron oxide magnetic nanoparticles by accumulating iron ion and crystalize them in the cell. This study aimed to construct novel microorganisms producing both magnetic particles and useful substances. In order to achieve this subject, we utilized and modified the gene set for magnetic particle synthesis from magnetotactic bacteria, and introduced the genes into selected host bacterial strains. Following results were obtained from this study. (1) Construction of magnetotactic bacterial strain containing minimum gene set for magnetic particle synthesis. (2) Selection of optimal host cell for magnetic particle formation. (3) Production of magnetic particles and useful substances in the host bacterial cell.
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