Identification of diagnostic biomarker and novel fusion genes of bone and soft tissue sarcoma

• Project/Area Number: 16H02676
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Orthopaedic surgery
• Research Institution: The University of Tokyo
• Principal Investigator: Matsuda Koichi 東京大学, 大学院新領域創成科学研究科, 教授 (90401257)
• Co-Investigator(Kenkyū-buntansha): 中村 卓郎 公益財団法人がん研究会, がん研究所 発がん研究部, 部長 (00180373) ; 中山 タラントロバート 慶應義塾大学, 医学部(信濃町), 講師 (00365298) ; 竹中 聡 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 整形外科部長 (00588379) ; 高阪 真路 国立研究開発法人国立がん研究センター, 研究所, ユニット長 (00627119) ; 松本 嘉寛 九州大学, 医学研究院, 准教授 (10346794) ; 植田 幸嗣 公益財団法人がん研究会, がんプレシジョン医療研究センター がんオーダーメイド医療開発プロジェクト, プロジェクトリーダー (10509110) ; 穴澤 卯圭 東京歯科大学, 歯学部, 教授 (20245525) ; 比留間 徹 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, 部長 (20254188) ; 河野 博隆 帝京大学, 医学部, 教授 (20345218) ; 阿江 啓介 公益財団法人がん研究会, 有明病院 整形外科, 部長 (20376726) ; 小林 寛 東京大学, 医学部附属病院, 講師 (20407951) ; 堀内 圭輔 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 整形外科学, 准教授 (30327564) ; 河本 旭哉 神戸大学, 医学研究科, 特命講師 (30420558) ; 平賀 博明 独立行政法人国立病院機構北海道がんセンター(臨床研究部), 臨床研究部, 教育研修部長 (30501530) ; 土屋 弘行 金沢大学, 医学系, 教授 (40227434) ; 坂本 昭夫 京都大学, 医学研究科, 講師 (40335964) ; 朴木 寛弥 奈良県立医科大学, 医学部, 教授 (40336863) ; 秋山 達 自治医科大学, 医学部, 教授 (40376471) ; 片山 琴絵 東京大学, 医科学研究所, 助教 (40581195) ; 大隈 知威 東京都立駒込病院(臨床研究室), 骨軟部腫瘍科, 医長 (40806189) ; 元井 亨 東京都立駒込病院(臨床研究室), 病理科, 医長 (50291315) ; 西田 佳弘 名古屋大学, 医学部附属病院, 病院教授 (50332698) ; 中川 英刀 国立研究開発法人理化学研究所, 生命医科学研究センター, チームリーダー (50361621) ; 平田 真 国立研究開発法人国立がん研究センター, 中央病院, 医員 (50401071) ; 米本 司 千葉県がんセンター(研究所), 整形外科, 部長 (50506318) ; 馬場 一郎 大阪医科大学, 医学部, 准教授 (60330073) ; 小田 義直 九州大学, 医学研究院, 教授 (70291515) ; 末原 義之 順天堂大学, 医学部, 客員教授 (70509405) ; 國定 俊之 岡山大学, 医歯薬学総合研究科, 准教授 (80346428) ; 山田 聡 名古屋市立大学, 医薬学総合研究院(医学), 講師 (80405208) ; 相羽 久輝 名古屋市立大学, 医薬学総合研究院(医学), 助教 (70793834) ; 松原 大祐 自治医科大学, 医学部, 准教授 (80415554) ; 川井 章 国立研究開発法人国立がん研究センター, 中央病院, 科長 (90252965) ; 筑紫 聡 愛知県がんセンター(研究所), 腫瘍免疫応答研究分野, 研究員 (90378109) ; 山口 類 愛知県がんセンター(研究所), システム解析学分野, 分野長 (90380675) ; 綿貫 宗則 東北大学, 大学病院, 講師 (90451575) ; 王谷 英達 大阪大学, 医学系研究科, 助教 (60727965) ; 吉川 秀樹 大阪大学, 医学系研究科, 理事・副学長 (60191558) ; 中 紀文 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 整形外科主任部長 (90601964) ; 岡本 健 京都大学, 医学研究科, 准教授 (30414113) ; 五嶋 孝博 東京都立駒込病院(臨床研究室), 骨軟部腫瘍科, 部長 (20272544) ; 岩田 慎太郎 千葉県がんセンター(研究所), 整形外科, 主任医長 (90549685)
• Project Period (FY): 2016-04-01 – 2021-03-31
• Project Status: Completed (Fiscal Year 2020)
• Budget Amount: ¥46,410,000 (Direct Cost: ¥35,700,000、Indirect Cost: ¥10,710,000); Fiscal Year 2020: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000); Fiscal Year 2019: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000); Fiscal Year 2018: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000); Fiscal Year 2017: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000); Fiscal Year 2016: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
• Keywords: 肉腫 / ゲノム解析 / がんゲノム / 骨軟部腫瘍 / 融合遺伝子 / 癌 / ゲノム / 整形外科 / 骨軟部肉腫

Outline of Final Research Achievements

In this research project, we conduced genome analysis and functional analysis of bone and soft tissue tumors to elucidate their molecular pathogenesis and developing new therapeutics. Through a collaborative network of Japan sarcoma genome consortium consisting of 28 medical institutions and 14 research institutes, pairs of tumor and normal tissue of 20 target diseases (dedifferentiated liposarcoma, giant synovial cell tumor, epithelial sarcoma, and osteoblastoma etc) were collected and RNA sequence and whole exome sequence of more than 400 samples was performed. As a result, CTDSP1 / 2-DNM3OS fusion (dedifferentiated liposarcoma) was identified as a disease-specific fusion gene. We also identified frequent CBL mutations in tenosynovial giant cell tumors and useful prognostic markers for Desmoid tumors.

Academic Significance and Societal Importance of the Research Achievements

本研究課題では28医療機関、14研究機関からなるオールジャパンの共同研究体制を通じて、希少がんである骨軟部腫瘍に対する試料・臨床情報収集、ゲノム解析の実施体制が構築された。20の組織型を対象に400例を超える検体を用いた大規模ゲノム解析の成果として、新規の疾患融合遺伝子が腱滑膜巨細胞腫や脱分化型脂肪肉腫で同定された。さらにデスモイド腫瘍や粘液型脂肪肉腫においては複数の予後マーカーが同定され、また骨肉腫に対する治療候補分子も同定された。これらの一連の成果は、希少がんである骨軟部腫瘍の発症メカニズムの解明だけでなく、診断・予後マーカーや新規治療法の開発などの臨床応用につながると期待される。

Research Products

• [Journal Article] Comprehensive molecular and clinicopathological profiling of desmoid tumours (2021)
  • Author(s): Kohsaka Shinji、Hirata Makoto、Ikegami Masachika、Ueno Toshihide、Kojima Shinya、Sakai Tomohisa、Ito Kan、Naka Norifumi、Ogura Koichi、Kawai Akira、Iwata Shintaro、Okuma Tomotake、Yonemoto Tsukasa、Kobayashi Hiroshi、Suehara Yoshiyuki、Hiraga Hiroaki、Kawamoto Teruya、Motoi Toru、Oda Yoshinao、Matsubara Daisuke、etc
  • Journal Title: European Journal of Cancer Volume: 145 Pages: 109-120
  • DOI: 10.1016/j.ejca.2020.12.001
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The simplified Kyoto classification score is consistent with the ABC method of classification as a grading system for endoscopic gastritis (2021)
  • Author(s): Nishizawa Toshihiro、Toyoshima Osamu、Kondo Ryo、Sekiba Kazuma、Tsuji Yosuke、Ebinuma Hirotoshi、Suzuki Hidekazu、Tanikawa Chizu、Matsuda Koichi、Koike Kazuhiko
  • Journal Title: Journal of Clinical Biochemistry and Nutrition Volume: 68 Issue: 1 Pages: 101-104
  • DOI: 10.3164/jcbn.20-41
  • NAID: 130007965311
  • ISSN: 0912-0009, 1880-5086
  • Peer Reviewed
• [Journal Article] A single nucleotide polymorphism in <i>Prostate Stem Cell Antigen</i> is associated with endoscopic grading in Kyoto classification of gastritis (2021)
  • Author(s): Toyoshima Osamu、Nishizawa Toshihiro、Sekiba Kazuma、Matsuno Tatsuya、Kondo Ryo、Watanabe Hidenobu、Suzuki Hidekazu、Tanikawa Chizu、Koike Kazuhiko、Matsuda Koichi
  • Journal Title: Journal of Clinical Biochemistry and Nutrition Volume: 68 Issue: 1 Pages: 73-77
  • DOI: 10.3164/jcbn.20-67
  • NAID: 130007965305
  • ISSN: 0912-0009, 1880-5086
  • Peer Reviewed
• [Journal Article] Population-based Screening for Hereditary Colorectal Cancer Variants in Japan (2020)
  • Author(s): Fujita Masashi、Liu Xiaoxi、Iwasaki Yusuke、Terao Chikashi、Mizukami Keijiro、Kawakami Eiryo、Takata Sadaaki、Inai Chihiro、Aoi Tomomi、Mizukoshi Misaki、Maejima Kazuhiro、Hirata Makoto、Murakami Yoshinori、Kamatani Yoichiro、Kubo Michiaki、Akagi Kiwamu、Matsuda Koichi、Nakagawa Hidewaki、Momozawa Yukihide
  • Journal Title: Clinical Gastroenterology and Hepatology Volume: 20 Issue: 9 Pages: 31664-31665
  • DOI: 10.1016/j.cgh.2020.12.007
• [Journal Article] Improving the trans-ancestry portability of polygenic risk scores by prioritizing variants in predicted cell-type-specific regulatory elements (2020)
  • Author(s): Amariuta Tiffany、Ishigaki Kazuyoshi、Sugishita Hiroki、Ohta Tazro、Koido Masaru、Dey Kushal K.、Matsuda Koichi、Murakami Yoshinori、Price Alkes L.、Kawakami Eiryo、Terao Chikashi、Raychaudhuri Soumya
  • Journal Title: Nature Genetics Volume: 52 Issue: 12 Pages: 1346-1354
  • DOI: 10.1038/s41588-020-00740-8
• [Journal Article] Endogenization and excision of human herpesvirus 6 in human genomes. (2020)
  • Author(s): Xiaoxi Liu, Shunichi Kosugi, Rie Koide, Yoshiki Kawamura, Jumpei Ito, Hiroki Miura, Nana Matoba, Motomichi Matsuzaki , and other 14 authors
  • Journal Title: PLOS Genetics Volume: 16 Issue: 8 Pages: 1008915-1008915
  • DOI: 10.1371/journal.pgen.1008915
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Chromosomal alterations among age-related haematopoietic clones in Japan (2020)
  • Author(s): Terao Chikashi、Suzuki Akari、Momozawa Yukihide、Akiyama Masato、Ishigaki Kazuyoshi、Yamamoto Kazuhiko、Matsuda Koichi、Murakami Yoshinori、McCarroll Steven A.、Kubo Michiaki、Loh Po-Ru、Kamatani Yoichiro
  • Journal Title: Nature Volume: 584 Issue: 7819 Pages: 130-135
  • DOI: 10.1038/s41586-020-2426-2
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases (2020)
  • Author(s): Ishigaki K, Akiyama M, Kanai M, Takahashi A, Kawakami E, Sugishita H, Sakaue S, Matoba N, Low SK, Okada Y, Yamaji T, et al
  • Journal Title: Nature Genetics Volume: 52 Issue: 7 Pages: 669-679
  • DOI: 10.1038/s41588-020-0640-3
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan (2020)
  • Author(s): Sakaue S, Kanai M, Karjalainen J, Akiyama M, Kurki M, Matoba N, Takahashi A, Hirata M, Kubo M, Matsuda K, Murakami Y; FinnGen, Daly MJ, Kamatani Y, Okada Y
  • Journal Title: Nat Med Volume: 26 Issue: 4 Pages: 542-548
  • DOI: 10.1038/s41591-020-0785-8
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] The Polygenic and Monogenic Basis of Blood Traits and Diseases (2020)
  • Author(s): Vuckovic Dragana、Bao Erik L.、Matsuda Koichi .、Soranzo Nicole et al.
  • Journal Title: Cell Volume: 182 Issue: 5 Pages: 1214-1231.e11
  • DOI: 10.1016/j.cell.2020.08.008
• [Journal Article] Genetic characterization of pancreatic cancer patients and prediction of carrier status of germline pathogenic variants in cancer-predisposing genes (2020)
  • Author(s): Mizukami Keijiro、Iwasaki Yusuke、Kawakami Eiryo、Hirata Makoto、Kamatani Yoichiro、Matsuda Koichi、Endo Mikiko、Sugano Kokichi、Yoshida Teruhiko、Murakami Yoshinori、Nakagawa Hidewaki、Spurdle Amanda B.、Momozawa Yukihide
  • Journal Title: EBioMedicine Volume: 60 Pages: 103033-103033
  • DOI: 10.1016/j.ebiom.2020.103033
  • Peer Reviewed / Open Access
• [Journal Article] Endoscopy-based Kyoto classification score of gastritis related to pathological topography of neutrophil activity (2020)
  • Author(s): Toyoshima Osamu、Nishizawa Toshihiro、Yoshida Shuntaro、Sakaguchi Yoshiki、Nakai Yousuke、Watanabe Hidenobu、Suzuki Hidekazu、Tanikawa Chizu、Matsuda Koichi、Koike Kazuhiko
  • Journal Title: World Journal of Gastroenterology Volume: 26 Issue: 34 Pages: 5146-5155
  • DOI: 10.3748/wjg.v26.i34.5146
  • Peer Reviewed / Open Access
• [Journal Article] Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease (2020)
  • Author(s): 2.Koyama S, Ito K, Terao C, Akiyama M, Horikoshi M, Momozawa Y, Matsunaga H, Ieki H, Ozaki K, Onouchi Y, Takahashi A, Nomura S, Morita H, Akazawa H, Kim C, Seo JS, Higasa K, Iwasaki M, Yamaji T, et al.
  • Journal Title: Nature Genetics Volume: 52 Issue: 11 Pages: 1169-1177
  • DOI: 10.1038/s41588-020-0705-3
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Fine Mapping of the Major Histocompatibility Complex Region and Association of the HLA-B*52:01 Allele With Cervical Cancer in Japanese Women (2020)
  • Author(s): Masuda Tatsuo、Ito Hidemi、Hirata Jun、Sakaue Saori、Ueda Yutaka、Kimura Tadashi、Takeuchi Fumihiko、Murakami Yoshinori、Matsuda Koichi、Matsuo Keitaro、Okada Yukinori
  • Journal Title: JAMA Network Open Volume: 3 Issue: 10 Pages: e2023248-e2023248
  • DOI: 10.1001/jamanetworkopen.2020.23248
  • Peer Reviewed / Open Access
• [Journal Article] Association of circulating 25-Hydroxyvitamin D and its related genetic variations with hepatocellular carcinoma incidence and survival (2020)
  • Author(s): Liu Hui、Jiang Xia、Qiao Qiaohua、Chen Liying、Matsuda Koichi、Jiang Guangyi、Yu Tunan、Wang Yifan、Lin Hui、Liang Xiao、Cai Xiujun
  • Journal Title: Annals of Translational Medicine Volume: 8 Issue: 17 Pages: 1080-1080
  • DOI: 10.21037/atm-20-1637
• [Journal Article] Integrated exome and RNA sequencing of dedifferentiated liposarcoma (2019)
  • Author(s): Hirata Makoto、Matsubara Daisuke (21th) etc
  • Journal Title: Nature Communications Volume: 10 Issue: 1 Pages: 1-12
  • DOI: 10.1038/s41467-019-13286-z
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Massively parallel sequencing of tenosynovial giant cell tumors reveals novel CSF1 fusion transcripts and novel somatic CBL mutations (2019)
  • Author(s): Tsuda Yusuke、Matsubara Daisuke (5th) etc
  • Journal Title: International Journal of Cancer Volume: 145 Issue: 12 Pages: 3276-3284
  • DOI: 10.1002/ijc.32421
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Frequent mutations of genes encoding vacuolar H+ -ATPase components in granular cell tumors. (2019)
  • Author(s): Sekimizu M, Yoshida A, Mitani S, Asano N, Hirata M, Kubo T, Yamazaki F, Sakamoto H, Kato M, Makise N, Mori T, Yamazaki N, Sekine S, Oda I, Watanabe SI, Hiraga H, Yonemoto T, Kawamoto T, Naka N, Funauchi Y, Nishida Y, Honoki K, Kawano H, Tsuchiya H, Kunisada T, Matsuda K, Inagaki K, Kawai A, Ichikawa H.
  • Journal Title: Genes Chromosomes Cancer Volume: 58 Issue: 6 Pages: 373-380
  • DOI: 10.1002/gcc.22727
  • Peer Reviewed / Open Access
• [Journal Article] Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation (2018)
  • Author(s): Owa Tomoo、Taya Shinichiro、Miyashita Satoshi、Yamashita Mariko、Adachi Toma、Yamada Koyo、Yokoyama Miwa、Aida Shogo、Nishioka Tomoki、Inoue Yukiko U.、Goitsuka Ryo、Nakamura Takuro、Inoue Takayoshi、Kaibuchi Kozo、Hoshino Mikio
  • Journal Title: The Journal of Neuroscience Volume: 38 Issue: 5 Pages: 1277-1294
  • DOI: 10.1523/jneurosci.1545-17.2017
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility (2018)
  • Author(s): Tanikawa Chizu、Ueda Koji、Suzuki Akari、Iida Aritoshi、Nakamura Ryoichi、Atsuta Naoki、Tohnai Genki、Sobue Gen、Saichi Naomi、Momozawa Yukihide、Kamatani Yoichiro、Kubo Michiaki、Yamamoto Kazuhiko、Nakamura Yusuke、Matsuda Koichi
  • Journal Title: Cell Reports Volume: 22 Issue: 6 Pages: 1473-1483
  • DOI: 10.1016/j.celrep.2018.01.031
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases (2018)
  • Author(s): Kanai M, Akiyama M, Takahashi A, Matoba N, Momozawa Y, Ikeda M, Iwata N, Ikegawa S, Hirata M, Matsuda K, Kubo M, Okada Y, Kamatani Y
  • Journal Title: Nat Genet Volume: 50 Issue: 3 Pages: 390-400
  • DOI: 10.1038/s41588-018-0047-6
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Diagnostic utility of histone H3.3 G34W, G34R, and G34V mutant-specific antibodies for giant cell tumors of bone (2018)
  • Author(s): Yamamoto Hidetaka、Iwasaki Takeshi、Yamada Yuichi、Matsumoto Yoshihiro、Otsuka Hiroshi、Yoshimoto Masato、Kohashi Kenichi、Taguchi Kenichi、Yokoyama Ryohei、Nakashima Yasuharu、Oda Yoshinao
  • Journal Title: Human Pathology Volume: 73 Pages: 41-50
  • DOI: 10.1016/j.humpath.2017.11.020
  • Peer Reviewed
• [Journal Article] SWI/SNF Chromatin-remodeling Complex Status in SMARCB1/INI1-preserved Epithelioid Sarcoma (2018)
  • Author(s): Kohashi Kenichi、Yamamoto Hidetaka、Yamada Yuichi、Kinoshita Izumi、Taguchi Tomoaki、Iwamoto Yukihide、Oda Yoshinao
  • Journal Title: The American Journal of Surgical Pathology Volume: 42 Issue: 3 Pages: 312-318
  • DOI: 10.1097/pas.0000000000001011
  • Peer Reviewed
• [Journal Article] Correction: Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor (2018)
  • Author(s): Fukushima Suguru、Endo Makoto、Matsumoto Yoshihiro、Fukushi Jun-ichi、Matsunobu Tomoya、Kawaguchi Ken-ichi、Setsu Nokitaka、IIda Keiichiro、Yokoyama Nobuhiko、Nakagawa Makoto、Yahiro Kenichiro、Oda Yoshinao、Iwamoto Yukihide、Nakashima Yasuharu
  • Journal Title: PLOS ONE Volume: 13 Issue: 3 Pages: 0194508-0194508
  • DOI: 10.1371/journal.pone.0194508
  • Peer Reviewed / Open Access
• [Journal Article] Secondary Chondrosarcoma Presenting with Symptoms Similar to Thoracic Outlet Syndrome (2018)
  • Author(s): Kobayashi Hiroshi、Ikegami Masachika、Ushiku Tetsuo、Anraku Masaki、Ohki Takahiro、Shinoda Yusuke、Tanaka Sakae、Kawano Hirotaka
  • Journal Title: Case Reports in Orthopedics Volume: 2018 Pages: 1-5
  • DOI: 10.1155/2018/9347145
  • Peer Reviewed
• [Journal Article] Time-Dependent Recovery of Human Synovial Membrane Mesenchymal Stem Cell Function After High-Dose Steroid Therapy: Case Report and Laboratory Study (2017)
  • Author(s): Yasui Yukihiko、Hart David A.、Sugita Norihiko、Chijimatsu Ryota、Koizumi Kota、Ando Wataru、Moriguchi Yu、Shimomura Kazunori、Myoui Akira、Yoshikawa Hideki、Nakamura Norimasa
  • Journal Title: The American Journal of Sports Medicine Volume: 46 Issue: 3 Pages: 695-701
  • DOI: 10.1177/0363546517741307
  • Peer Reviewed
• [Journal Article] Trabectedin is a promising antitumor agent potentially inducing melanocytic differentiation for clear cell sarcoma (2017)
  • Author(s): Nakai Takaaki、Imura Yoshinori、Tamiya Hironari、Yamada Shutaro、Nakai Sho、Yasuda Naohiro、Kaneko Keiko、Outani Hidetatsu、Takenaka Satoshi、Hamada Kenichiro、Myoui Akira、Araki Nobuhito、Ueda Takafumi、Itoh Kazuyuki、Yoshikawa Hideki、Naka Norifumi
  • Journal Title: Cancer Medicine Volume: 6 Issue: 9 Pages: 2121-2130
  • DOI: 10.1002/cam4.1130
  • Peer Reviewed / Open Access
• [Journal Article] Clinical outcomes of patients with epithelioid sarcomas: impact and management of nodal metastasis (2017)
  • Author(s): Outani Hidetatsu、Imura Yoshinori、Tanaka Takaaki、Takenaka Satoshi、Oshima Kazuya、Hamada Kenichiro、Kakunaga Shigeki、Joyama Susumu、Naka Norifumi、Kudawara Ikuo、Ueda Takafumi、Araki Nobuhito、Yoshikawa Hideki
  • Journal Title: International Journal of Clinical Oncology Volume: 23 Issue: 1 Pages: 181-188
  • DOI: 10.1007/s10147-017-1179-x
  • Peer Reviewed
• [Journal Article] Clinical significance of circulating miR-25-3p as a novel diagnostic and prognostic biomarker in osteosarcoma (2017)
  • Author(s): Fujiwara T, Uotani K, Yoshida A, Morita T, Nezu Y, Kobayashi E, Yoshida A5, Uehara T1, Omori T1, Sugiu K1, Komatsubara T, Takeda K, Kunisada T, Kawamura M, Kawai A, Ochiya T, Ozaki T
  • Journal Title: Oncotarget Volume: - Issue: 20 Pages: 33375-33392
  • DOI: 10.18632/oncotarget.16498
  • Peer Reviewed / Open Access
• [Journal Article] Role of zoledronic acid in oncolytic virotherapy: Promotion of antitumor effect and prevention of bone destruction (2017)
  • Author(s): Yamakawa Yasuaki、Tazawa Hiroshi、Hasei Joe、Osaki Shuhei、Omori Toshinori、Sugiu Kazuhisa、Komatsubara Tadashi、Uotani Kouji、Fujiwara Tomohiro、Yoshida Aki、Kunisada Toshiyuki、Urata Yasuo、Kagawa Shunsuke、Ozaki Toshifumi、Fujiwara Toshiyoshi
  • Journal Title: Cancer Science Volume: 108 Issue: 9 Pages: 1870-1880
  • DOI: 10.1111/cas.13316
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Circulating MicroRNA-92b-3p as a Novel Biomarker for Monitoring of Synovial Sarcoma (2017)
  • Author(s): Uotani Koji、Fujiwara Tomohiro、Yoshida Aki、Iwata Shintaro、Morita Takuya、Kiyono Masahiro、Yokoo Suguru、Kunisada Toshiyuki、Takeda Ken、Hasei Joe、Numoto Kunihiko、Nezu Yutaka、Yonemoto Tsukasa、Ishii Takeshi、Kawai Akira、Ochiya Takahiro、Ozaki Toshifumi
  • Journal Title: Scientific Reports Volume: 7 Issue: 1 Pages: 14634-14634
  • DOI: 10.1038/s41598-017-12660-5
  • Peer Reviewed / Open Access
• [Journal Article] Takuro Nakamura CIC-DUX4 induces small round cell sarcomas distinct from Ewing sarcoma (2017)
  • Author(s): Yoshimoto T, Tanaka M, Homme M, Yamazaki Y, Takazawa Y, Antonescu CR, Nakamura T
  • Journal Title: Cancer Res Volume: 印刷中 Issue: 11 Pages: 2927-2937
  • DOI: 10.1158/0008-5472.can-16-3351
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] A double-edged sword: The world according to Capicua in cancer. (2017)
  • Author(s): Tanaka M, Yoshimoto T, Nakamura T.
  • Journal Title: Cancer Science Volume: 108(12) Issue: 12 Pages: 2319-2325
  • DOI: 10.1111/cas.13413
  • Peer Reviewed / Open Access
• [Journal Article] Identification of a p53 target, CD137L, that mediates growth suppression and immune response of osteosarcoma cells (2017)
  • Author(s): Tsuda Y, Tanikawa C, Miyamoto T, Hirata M, Yodsurang V, Zhang YZ, Imoto S, Yamaguchi R, Miyano S, Takayanagi H, Kawano H, Nakagawa H, Tanaka S, Matsuda K
  • Journal Title: Sci Rep Volume: 7(1) Issue: 1 Pages: 10739-10739
  • DOI: 10.1038/s41598-017-11208-x
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Genome-wide association study identifies 112 new loci for body mass index in the Japanese population (2017)
  • Author(s): Akiyama M, Okada Y, Kanai M, Takahashi A, Momozawa Y, Ikeda M, Iwata N, Ikegawa S, Hirata M, Matsuda K, Iwasaki M, Yamaji T, Sawada N, Hachiya T, Tanno K, Shimizu A, Hozawa A, Minegishi N, Tsugane S, Yamamoto M, Kubo M and Kamatani Y
  • Journal Title: Nat Genet Volume: 49 Issue: 10 Pages: 1458-1462
  • DOI: 10.1038/ng.3951
  • Peer Reviewed / Open Access
• [Journal Article] Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway (2017)
  • Author(s): Takahashi Yukie、Tanikawa Chizu、Miyamoto Takafumi、Hirata Makoto、Wang Guanxiong、Ueda Koji、Komatsu Tsunehiko、Matsuda Koichi
  • Journal Title: International Journal of Oncology Volume: 51 Issue: 2 Pages: 724-736
  • DOI: 10.3892/ijo.2017.4060
  • Peer Reviewed
• [Journal Article] Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p53 (2017)
  • Author(s): Miyamoto Takafumi、Lo Paulisally Hau Yi、Saichi Naomi、Ueda Koji、Hirata Makoto、Tanikawa Chizu、Matsuda Koichi
  • Journal Title: Science Advances Volume: 3 Issue: 5 Pages: 1603204-1603204
  • DOI: 10.1126/sciadv.1603204
  • Peer Reviewed / Open Access
• [Journal Article] Extracellular vesicles isolated from human renal cell carcinoma tissues disrupt vascular endothelial cell morphology via azurocidin (2017)
  • Author(s): Jingushi Kentaro、Uemura Motohide、Ohnishi Naomi、Nakata Wataru、Fujita Kazutoshi、Naito Takuya、Fujii Risa、Saichi Naomi、Nonomura Norio、Tsujikawa Kazutake、Ueda Koji
  • Journal Title: International Journal of Cancer Volume: 142 Issue: 3 Pages: 607-617
  • DOI: 10.1002/ijc.31080
  • Peer Reviewed / Open Access
• [Journal Article] p53-independent p21 induction by MELK inhibition (2017)
  • Author(s): Matsuda Tatsuo、Kato Taigo、Kiyotani Kazuma、Tarhan Yunus Emre、Saloura Vassiliki、Chung Suyoun、Ueda Koji、Nakamura Yusuke、Park Jae-Hyun
  • Journal Title: Oncotarget Volume: 8 Issue: 35 Pages: 57938-57947
  • DOI: 10.18632/oncotarget.18488
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Cabozantinib and dastinib exert anti-tumor activity in alveolar soft part sarcoma (2017)
  • Author(s): Mukaihara K, Tanabe Y, Kubota D, Akaike K, Hayashi T, Mogushi K, Hosoya M, Sato S,Kobayashi E, Okubo T, Kohsaka S, Saito T, Kaneko K, Suehara Y.
  • Journal Title: PLoS One Volume: 12(9) Issue: 9 Pages: 0185321-0185321
  • DOI: 10.1371/journal.pone.0185321
  • Peer Reviewed / Open Access
• [Journal Article] MAGEA4 expression in bone and soft tissue tumors: its utility as a target for immunotherapy and diagnostic marker combined with NY-ESO-1 (2017)
  • Author(s): Iura Kunio、Kohashi Kenichi、Ishii Takeaki、Maekawa Akira、Bekki Hirofumi、Otsuka Hiroshi、Yamada Yuichi、Yamamoto Hidetaka、Matsumoto Yoshihiro、Iwamoto Yukihide、Oda Yoshinao
  • Journal Title: Virchows Archiv Volume: 471 Issue: 3 Pages: 383-392
  • DOI: 10.1007/s00428-017-2206-z
  • Peer Reviewed
• [Journal Article] Efficacy of Trabectedin in Patients with Advanced Translocation‐Related Sarcomas: Pooled Analysis of Two Phase II Studies (2017)
  • Author(s): Takahashi Mitsuru、Takahashi Shunji、Araki Nobuhito、Sugiura Hideshi、Ueda Takafumi、Yonemoto Tsukasa、Morioka Hideo、Hiraga Hiroaki、Hiruma Toru、Kunisada Toshiyuki、Matsumine Akihiko、Shimura Masashi、Kawai Akira
  • Journal Title: The Oncologist Volume: 22 Issue: 8 Pages: 979-988
  • DOI: 10.1634/theoncologist.2016-0064
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Analysis of the Infiltrative Features of Chordoma: The Relationship Between Micro-Skip Metastasis and Postoperative Outcomes (2017)
  • Author(s): Akiyama Toru、Ogura Koichi、Gokita Tabu、Tsukushi Satoshi、Iwata Shintaro、Nakamura Tomoki、Matsumine Akihiko、Yonemoto Tsukasa、Nishida Yoshihiro、Saita Kazuo、Kawai Akira、Matsumoto Seiichi、Yamaguchi Takehiko
  • Journal Title: Annals of Surgical Oncology Volume: 25 Issue: 4 Pages: 912-919
  • DOI: 10.1245/s10434-017-6268-6
  • Peer Reviewed
• [Journal Article] Metabolic Tumor Volume by 18F-FDG PET/CT Can Predict the Clinical Outcome of Primary Malignant Spine/Spinal Tumors (2017)
  • Author(s): Matsumoto Yoshihiro、Baba Shingo、Endo Makoto、Setsu Nokitaka、Iida Keiichiro、Fukushi Jun-Ichi、Kawaguchi Kenichi、Okada Seiji、Bekki Hirofumi、Isoda Takuro、Kitamura Yoshiyuki、Honda Hiroshi、Nakashima Yasuharu
  • Journal Title: BioMed Research International Volume: 2017 Pages: 1-8
  • DOI: 10.1155/2017/8132676
  • Peer Reviewed
• [Journal Article] Activation of ERK1/2 Causes Pazopanib Resistance via Downregulation of DUSP6 in Synovial Sarcoma Cells (2017)
  • Author(s): Yokoyama N, Matsunobu T, Matsumoto Y, Fukushi J, Endo M, Hatano M, Nabeshima A, Fukushima S, Okada S, and Iwamoto Y
  • Journal Title: ScイエンチフィcRえぽrts Volume: 7 Issue: 1 Pages: 45332-45332
  • DOI: 10.1038/srep45332
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Prevalence and clinical outcomes of hip fractures and subchondral insufficiency fractures of the femoral head in patients with tumour-induced osteomalacia (2017)
  • Author(s): Kobayashi Hiroshi、Ito Nobuaki、Akiyama Toru、Okuma Tomotake、Kinoshita Yuka、Ikegami Masachika、Shinoda Yusuke、Fukumoto Seiji、Tanaka Sakae、Kawano Hirotaka
  • Journal Title: International Orthopaedics Volume: 41 Issue: 12 Pages: 2597-2603
  • DOI: 10.1007/s00264-017-3610-3
  • Peer Reviewed
• [Journal Article] Neutrophil-to-lymphocyte ratio after pazopanib treatment predicts response in patients with advanced soft-tissue sarcoma (2017)
  • Author(s): Kobayashi Hiroshi、Okuma Tomotake、Oka Hiroyuki、Hirai Toshihide、Ohki Takahiro、Ikegami Masachika、Sawada Ryoko、Shinoda Yusuke、Akiyama Toru、Sato Kenji、Abe Satoshi、Kawano Hirotaka、Goto Takahiro、Tanaka Sakae
  • Journal Title: International Journal of Clinical Oncology Volume: 23 Issue: 2 Pages: 368-374
  • DOI: 10.1007/s10147-017-1199-6
  • Peer Reviewed
• [Journal Article] SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters (2017)
  • Author(s): Nakayama Robert T、Pulice John L、Valencia Alfredo M、McBride Matthew J、McKenzie Zachary M、Gillespie Mark A、Ku Wai Lim、Teng Mingxiang、Cui Kairong、Williams Robert T、Cassel Seth H、Qing He、Widmer Christian J、Demetri George D、Irizarry Rafael A、Zhao Keji、Ranish Jeffrey A、Kadoch Cigall
  • Journal Title: Nature Genetics Volume: 49 Issue: 11 Pages: 1613-1623
  • DOI: 10.1038/ng.3958
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Wide-spread ignorance on the treatment of subcutaneous malignant tumors; a questionnaire-based study (2017)
  • Author(s): Kikuta Kazutaka、Nakayama Robert、Yamaguchi Sayaka、Nishiwaki Yuuji、Susa Michiro、Nishimoto Kazumasa、Horiuchi Keisuke、Nakamura Masaya、Matsumoto Morio、Morioka Hideo
  • Journal Title: Japanese Journal of Clinical Oncology Volume: 48 Issue: 2 Pages: 130-134
  • DOI: 10.1093/jjco/hyx184
  • Peer Reviewed
• [Journal Article] A histological positive margin after surgery is correlated with high local re-recurrence rate in patients with recurrent myxofibrosarcoma (2017)
  • Author(s): Kikuta K, Nakayama R, Yoshida A, Sasaki A, Kameyama K, Chuman H, Kawai A, Nakamura M, Matsumoto M, Morioka H
  • Journal Title: Japanese Journal of Clinical Oncology Volume: 47 (4) Issue: 4 Pages: 334-341
  • DOI: 10.1093/jjco/hyw199
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Mesenchymal chondrosarcoma: A Japanese Musculoskeletal Oncology Group (JMOG) study on 57 patients (2017)
  • Author(s): Tsuda Yusuke、Ogura Koichi、Hakozaki Michiyuki、Kikuta Kazutaka、Ae Keisuke、Tsuchiya Hiroyuki、Iwata Shintaro、Ueda Takafumi、Kawano Hirotaka、Kawai Akira
  • Journal Title: Journal of Surgical Oncology Volume: 115 Issue: 6 Pages: 760-767
  • DOI: 10.1002/jso.24567
  • Peer Reviewed
• [Journal Article] Pulmonary metastasis from giant cell tumor of bone: clinical outcome prior to the introduction of molecular target therapy. (2017)
  • Author(s): Kito M, Matusmoto S, Ae K, Tanizawa T, Gokita T, Kobayashi H, Hayakawa K, Funauchi Y.
  • Journal Title: Jpn J Clin Oncol Volume: 4-Mar Issue: 6 Pages: 1-6
  • DOI: 10.1093/jjco/hyx033
  • Peer Reviewed
• [Journal Article] Tenosynovial giant cell tumour of the hand in children under 10 years of age (2017)
  • Author(s): Tsujino Shohei、Matsumoto Seiichi、Ae Keisuke
  • Journal Title: Journal of Hand Surgery (European Volume) Volume: 43 Issue: 3 Pages: 335-337
  • DOI: 10.1177/1753193417739518
  • Peer Reviewed
• [Journal Article] Antitumor effects of 4-methylumbelliferone, a hyaluronan synthesis inhibitor, on malignant peripheral nerve sheath tumor. (2017)
  • Author(s): Ikuta K, Ota T, Zhuo L, Urakawa H, Kozwa E, Hamada S, Kimata K, Ishiguro N, Nishida Y.
  • Journal Title: Int J Cancer Volume: 140 Issue: 2 Pages: 469-479
  • DOI: 10.1002/ijc.30460
  • NAID: 120006220417
  • Peer Reviewed / Open Access
• [Journal Article] Cross-cultural adaptation and validation of the Japanese version of the Toronto Extremity Salvage Score (TESS) for patients with malignant musculoskeletal tumors in the upper extremities. (2017)
  • Author(s): Akiyama T, Uehara K, Ogura K, Shinoda Y, Iwata S, Saita K, Tanzawa Y, Nakatani F, Yonemoto T, Kawano H, Davis AM, Kawai A.
  • Journal Title: J Orthop Sci. Volume: 22(1) Issue: 1 Pages: 127-132
  • DOI: 10.1016/j.jos.2016.09.012
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Skeletal-related events and prognosis in urothelial cancer patients with bone metastasis. (2017)
  • Author(s): Tsuda Y, Nakagawa T, Shinoda Y, Kanatani A, Kawai T, Taguchi S, Yamada Y, Sawada R, Kume H, Homma Y, Tanaka S, Kawano H.
  • Journal Title: Int J Clin Oncol. Volume: Epub ahead of print Issue: 3 Pages: 548-553
  • DOI: 10.1007/s10147-016-1075-9
  • Peer Reviewed
• [Journal Article] Impact of geriatric factors on surgical and prognostic outcomes in elderly patients with soft-tissue sarcoma. (2017)
  • Author(s): Tsuda Y, Ogura K, Kobayashi E, Hiruma T, Iwata S, Asano N, Kawai A, Chuman H, Ishii T, Morioka H, Kobayashi H, Kawano H.
  • Journal Title: Jpn J Clin Oncol Volume: 2017/2/15 Issue: 5 Pages: 1-8
  • DOI: 10.1093/jjco/hyx016
  • Peer Reviewed / Open Access
• [Journal Article] Three-dimensional fluoroscopic navigation-assisted surgery for tumors in patients with tumor-induced osteomalacia in the bones. (2017)
  • Author(s): Kobayashi H, Akiyama T, Okuma T, Shinoda Y, Oka H, Ito N, Fukumoto S, Tanaka S, Kawano H.
  • Journal Title: Comput Assist Surg Volume: 12 Issue: 1 Pages: 1-14
  • DOI: 10.1080/24699322.2017.1282044
  • Peer Reviewed / Open Access
• [Journal Article] Anterior Impingement Syndrome of the Ankle Caused by Osteoid Osteoma in the Talar Neck Treated with Arthroscopy and 3D C-Arm-Based Imaging (2017)
  • Author(s): Masachika Ikegami, Takumi Matsumoto, Song Ho Chang, Hiroshi Kobayashi, Yusuke Shinoda, and Sakae Tanaka
  • Journal Title: Case Reports in Orthopedics Volume: 2017 Pages: 2171627-2171627
  • DOI: 10.1155/2017/2171627
  • Peer Reviewed / Open Access
• [Journal Article] Best practices for the Management of Local-regional Recurrent Chordoma. A Position Paper by the Chordoma Global Consensus Group. (2017)
  • Author(s): Stacchiotti S, Gronchi A, Fossati P, Akiyama T, Alapetite C, Baumann M, Blay JY, Bolle S, Boriani S, Bruzzi P, Capanna R, Caraceni A, Casadei R, Colia V, Debus J, Delaney T, Desai A, Dileo P, Dijkstra S, Doglietto F, Flanagan A, Froelich S,
  • Journal Title: Ann Oncol. Volume: Epib Issue: 6 Pages: 1230-1242
  • DOI: 10.1093/annonc/mdx054
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Modeling alveolar soft part sarcoma unveils novel mechanisms of metastasis. (2017)
  • Author(s): Tanaka M, Homme M, Yamazaki Y, Shimizu R, Takazawa Y, Nakamura T
  • Journal Title: Cancer Res Volume: 77 Issue: 4 Pages: 897-904
  • DOI: 10.1158/0008-5472.can-16-2486
  • Peer Reviewed
• [Journal Article] Clinicopathological and molecular characterization of SMARCA4-deficient thoracic (2017)
  • Author(s): Yoshida A, Kobayashi E, Kubo T, Kodaira M, Motoi T, Motoi N, Yonemori K, Ohe
  • Journal Title: Modern Pathology Volume: 印刷中 Issue: 6 Pages: 797-809
  • DOI: 10.1038/modpathol.2017.11
  • Peer Reviewed
• [Journal Article] Angiofibroma of Soft Tissue on the Cheek: Diagnosis Confirmed by Gene Rearrangem (2017)
  • Author(s): Jeong JW, Kono M, Hasegawa-Murakami Y, Motoi T, Yokota K, Matsumoto T, Kaibu
  • Journal Title: Acta Derm Venereol Volume: 4;97(1) Pages: 133-134
  • Peer Reviewed
• [Journal Article] Sequence-specific bias correction for RNA-seq data using recurrent neural networks (2017)
  • Author(s): Zhang Y-Z, Yamaguchi R, Imoto S, Miyano S
  • Journal Title: BMC Genomics Volume: 18(Suppl 1) Issue: S1 Pages: 1044-1044
  • DOI: 10.1186/s12864-016-3262-5
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p53 (2017)
  • Author(s): T. Miyamoto, P. H. Y. Lo, N. Saichi, K. Ueda, M. Hirata, C. Tanikawa, K. Matsuda
  • Journal Title: Science Advance Volume: In press
  • Peer Reviewed
• [Journal Article] EPSIN 3, A Novel p53 Target, Regulates the Apoptotic Pathway and Gastric Carcinogenesis. (2017)
  • Author(s): Mori J, Tanikawa C, Ohnishi N, Funauchi Y, Toyoshima O, Ueda K, Matsuda K.
  • Journal Title: Neoplasia Volume: 19 Issue: 3 Pages: 185-195
  • DOI: 10.1016/j.neo.2016.12.010
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Extra-articular diffuse-type tenosynovial giant cell tumor with benign histological features resulting in fatal pulmonary metastases. (2017)
  • Author(s): Osanai T, Suzuki H, Hiraga H, Soma T, Nojima T.
  • Journal Title: J Orthop Surg Volume: 25(1) Issue: 1 Pages: 1-5
  • DOI: 10.1177/2309499017690323
  • Peer Reviewed
• [Journal Article] Simple resection of truncal desmoid tumors: A case series. (2016)
  • Author(s): Nishida Y, Tsukushi S, Urakawa H, Hamada S, Kozawa E, Ikuta K, Ishiguro N.
  • Journal Title: Oncology Letters Volume: 12 Issue: 2 Pages: 1564-1568
  • DOI: 10.3892/ol.2016.4792
  • NAID: 120005868225
  • Peer Reviewed / Open Access
• [Journal Article] Giant cell tumor of bone arising in long bones possibly originates from the metaphyseal region. (2016)
  • Author(s): Futamura N, Urakawa H, Tsukushi S, Arai E, Kozawa E, Ishiguro N, Nishida Y.
  • Journal Title: Oncology Letters Volume: 11 Issue: 4 Pages: 2629-2634
  • DOI: 10.3892/ol.2016.4264
  • NAID: 120005844106
  • Peer Reviewed / Open Access
• [Journal Article] Risk factors for distant metastasis of dermatofibrosarcoma protuberans (2016)
  • Author(s): Hayakawa, K., Matsumoto, S., Ae, K., Tanizawa, T., Gokita, T., Funauchi, Y., Motoi, N.
  • Journal Title: J. Orthop. Traumatol. Volume: 17(3) Issue: 3 Pages: 261-6
  • DOI: 10.1007/s10195-016-0415-x
  • Peer Reviewed
• [Journal Article] Risk factors for pneumothorax in advanced and/or metastatic soft tissue sarcoma patients during pazopanib treatment: a single-institute analysis (2016)
  • Author(s): Nakano, K., Motoi, N., Tomomatsu, J., Gokita, T., Ae, K., Tanizawa, T., Matsumoto, S., Takahashi, S.
  • Journal Title: BMC Cancer Volume: 16(1) Issue: 1 Pages: 750-750
  • DOI: 10.1186/s12885-016-2786-z
  • Peer Reviewed / Open Access
• [Journal Article] High serum ALP level is associated with increased risk of denosumab-related hypocalcemia in patients with bone metastases from solid tumors (2016)
  • Author(s): Kinoshita Y, Arai M, Ito N, Takashi Y, Makita N, Nangaku M, Shinoda Y, Fukumoto S.
  • Journal Title: Endocrine Journal Volume: 63 Issue: 5 Pages: 479-484
  • DOI: 10.1507/endocrj.EJ16-0003
  • NAID: 130005154205
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  • Peer Reviewed / Open Access
• [Journal Article] Inferior gluteal artery detection at the greater sciatic notch with a computer-assisted navigation system during pelvic and sacral tumor resection. (2016)
  • Author(s): Akiyama T, Kanda S, Maeda A, Saita K.
  • Journal Title: Comput Assist Surg (Abingdon) Volume: 21(1) Issue: 1 Pages: 18-24
  • DOI: 10.3109/24699322.2016.1174305
  • Peer Reviewed / Open Access
• [Journal Article] Reconstruction of the Midfoot Using a Free Vascularized Fibular Graft After En Bloc Excision for Giant Cell Tumor of the Tarsal Bones: A Case Report. (2016)
  • Author(s): Hara H, Kawamoto T, Onishi Y, Fujioka H, Nishida K, Kuroda R, Kurosaka M, Akisue T.
  • Journal Title: J Foot Ankle Surg Volume: 55 Issue: 4 Pages: 838-841
  • DOI: 10.1053/j.jfas.2015.04.020
  • Peer Reviewed
• [Journal Article] Large-scale mutational analysis in the EXT1 and EXT2 genes for Japanese patients with multiple osteochondromas. (2016)
  • Author(s): Ishimaru D, Gotoh M, Takayama S, Kosaki R, Matsumoto Y, Narimatsu H, Sato T, Kimata K, Akiyama H, Shimizu K, Matsumoto K.
  • Journal Title: BMC Genet. Volume: 17 Issue: 1 Pages: 52-52
  • DOI: 10.1186/s12863-016-0359-4
  • Peer Reviewed / Open Access
• [Journal Article] Dumbbell Scoring System: A New Method for the Differential Diagnosis of Malignant and Benign Spinal Dumbbell Tumors. (2016)
  • Author(s): Matsumoto Y, Harimaya K, Kawaguchi K, Hayashida M, Okada S, Doi T, Iwamoto Y.
  • Journal Title: Spine Volume: 41 Issue: 20 Pages: E1230-E1236
  • DOI: 10.1097/brs.0000000000001582
  • Peer Reviewed
• [Journal Article] MEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis. (2016)
  • Author(s): Yokoyama T, Nakatake M, Kuwata T, Couiznet A, Goitsuka R, Tsutsumi S, Aburatani H, Valk PJ, Delwel R, Nakamura T.
  • Journal Title: J Clin Invest. Volume: 印刷中 Issue: 5 Pages: 1664-1678
  • DOI: 10.1172/jci81516
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model (2016)
  • Author(s): Minas TZ, Surdez D, Tahereh J, Tanak M, Howarth M, Kang HJ, Han J, Han ZY, Sax B, Kream BE, Hong SH, Tirode F, Tuckermann J, Toretsky JA, Kenner L, Kovar H, Lee S, Sweet-Cordero A, Nakamura T, Moriggi R, Delattre O, Uren A
  • Journal Title: Oncotarget Volume: May 15 Issue: 21 Pages: 9388-9388
  • DOI: 10.18632/oncotarget.9388
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The clinical outcome of pazopanib treatment in Japanese patients with relapsed soft tissue sarcoma: A Japanese Musculoskeletal Oncology Group (JMOG) study. (2016)
  • Author(s): Nakamura T, Matsumine A, Kawai A, Araki N, Goto T, Yonemoto T, Sugiura H, Nishida Y, Hiraga H, Honoki K, Yasuda T, Boku S, Sudo A, Ueda T.
  • Journal Title: Cancer Volume: 122(9) Issue: 9 Pages: 1408-1416
  • DOI: 10.1002/cncr.29961
  • Peer Reviewed / Open Access
• [Journal Article] Reliability and validity of a Japanease-language and culturally adapted version of the Musculoskeletal Tumor Society scoring system for the lower extremity. (2016)
  • Author(s): Iwata S, Uehara K, Ogura K, Akiyama T, Shinoda Y, Yonemoto T, Kawai A
  • Journal Title: Clin Orthop Relat Res Volume: 474(9) Issue: 9 Pages: 2044-2052
  • DOI: 10.1007/s11999-016-4880-6
  • Peer Reviewed / Open Access
• [Journal Article] Results of sub-analysis of a phase 2 study on trabectedin treatment for extraskeletal myxoid chondrosarcoma and mesenchymal chondrosarcoma. (2016)
  • Author(s): Morioka H, Takahashi S, Araki N, Sugiura H, Ueda T, Takahashi M, Yonemoto T, Hiraga H, Hiruma T, Kunisada T, Matsumine A, Susa M, Nakayama R, Nishimoto K, Kikuta K, Horiuchi K, Kawai A
  • Journal Title: BMC Cancer Volume: 16 Issue: 1 Pages: 479-479
  • DOI: 10.1186/s12885-016-2511-y
  • Peer Reviewed / Open Access
• [Journal Article] Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma. (2016)
  • Author(s): Nakayama R, Zhang YX, Czaplinski JT, Anatone AJ, Sicinska ET, Fletcher JA, Demetri GD, Wagner AJ
  • Journal Title: Oncotarget Volume: Mar 29;7(13) Issue: 13 Pages: 16581-92
  • DOI: 10.18632/oncotarget.7667
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Forty-eight cases of leiomyosarcoma of bone in Japan: A multicenter study from the Japanese musculoskeletal oncology group. (2016)
  • Author(s): Mori T, Nakayama R, Endo M, Hiraga H, Tomita M, Fukase N, Kobayashi E, Kawai A, Ueda T, Morioka H.
  • Journal Title: J Surg Oncol Volume: Sep;114(4) Issue: 4 Pages: 495-500
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  • Peer Reviewed / Open Access
• [Journal Article] FOSL1 immunohistochemistry clarifies the distinction between desmoplastic fibrob (2016)
  • Author(s): Kato I, Yoshida A, Ikegami M, Okuma T, Tonooka A, Horiguchi S, Funata N, Kaw
  • Journal Title: Histopathology Volume: 69(6) Issue: 6 Pages: 1012-1020
  • DOI: 10.1111/his.13042
  • Peer Reviewed
• [Journal Article] Prognostic Significance of Forkhead Box M1 (FOXM1) Expression and Antitumor Effect of FOXM1 Inhibition in Angiosarcoma. (2016)
  • Author(s): Ito T, Kohashi K, Yamada Y, Iwasaki T, Maekawa A, Kuda M, Hoshina D, Abe R, Furue M, Oda Y.
  • Journal Title: J Cancer Volume: Apr 27;7(7) Issue: 7 Pages: 823-30
  • DOI: 10.7150/jca.14461
  • Peer Reviewed / Open Access
• [Journal Article] Reclassification of rhabdoid tumor and pediatric undifferentiated/unclassified sarcoma with complete loss of SMARCB1/INI1 protein expression: three subtypes of rhabdoid tumor according to their histological features. (2016)
  • Author(s): Kohashi K, Tanaka Y, Kishimoto H, Yamamoto H, Yamada Y, Taguchi T, Iwamoto Y, Oda Y.
  • Journal Title: Mod Pathol Volume: Oct;29(10) Pages: 1232-42
  • Peer Reviewed
• [Journal Article] Cancer-testis antigen expression in synovial sarcoma: NY-ESO-1, PRAME, MAGEA4, and MAGEA1. (2016)
  • Author(s): Iura K, Maekawa A, Kohashi K, Ishii T, Bekki H, Otsuka H, Yamada Y, Yamamoto H, Harimaya K, Iwamoto Y, Oda Y.
  • Journal Title: Hum Pathol Volume: Mar;61 Pages: 130-139
  • DOI: 10.1016/j.humpath.2016.12.006
  • Peer Reviewed
• [Journal Article] Large skin ulcer due to a subcutaneous orthopedic implant after bevacizumab therapy: (2016)
  • Author(s): Suehara Y*, Osawa H, Kubota D, Kato S, Akaike K, Tanabe Y, Saito T, Kaneko K.
  • Journal Title: J Bone Joint Surg Volume: 6 (3) Issue: 3 Pages: e70-e70
  • DOI: 10.2106/jbjs.cc.15.00281
  • Peer Reviewed / Open Access
• [Journal Article] Expression of F-actin-capping protein subunit beta is associated with cell growth and motility in epithelioid sarcoma. (2016)
  • Author(s): Mukaihara K, Suehara Y*, Kohsaka S, Kubota D, Toda-Ishii M, Akaike K, Fujimura T, Kobayashi E, Yao T, Ladanyi, M, Kaneko K, Saito T.
  • Journal Title: BMC cancer. Volume: 16(1) Issue: 1 Pages: 206-206
  • DOI: 10.1186/s12885-016-2235-z
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Protein Expression Profiling of Giant Cell Tumors of Bone Treated with Denosumab. (2016)
  • Author(s): Mukaihara K, Suehara Y, Kohsaka S, Akaike K, Tanabe Y, Kubota D, Ishii M, Fujimura T, Kazuno S, Okubo T, Takagi T, Yao T, Kaneko K, Saito T.
  • Journal Title: PLoS One Volume: 10 Issue: 2 Pages: e0148401-e0148401
  • DOI: 10.1371/journal.pone.0148401
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Risk factors for surgical site infection after posterior fixation surgery and intraoperative radiotherapy for spinal metastases. (2016)
  • Author(s): Sugita S, Hozumi T, Yamakawa K, Goto T, Kondo T.
  • Journal Title: Eur Spine J. Volume: 25(4) Issue: 4 Pages: 1034-1038
  • DOI: 10.1007/s00586-015-4116-6
  • Peer Reviewed / Open Access
• [Journal Article] Prognostic significance of intensive local therapy to bone lesions in renal cell carcinoma patients with bone metastasis (2016)
  • Author(s): Fukushima H, Hozumi T, Goto T, Nihei K, Karasawa K, Nakanishi Y, Kataoka M, Tobisu K, Koga F.
  • Journal Title: Clinical and Experimental Metastasis Volume: 33(7) Issue: 7 Pages: 699-705
  • DOI: 10.1007/s10585-016-9805-y
  • Peer Reviewed / Open Access
• [Journal Article] Long-term Follow-up of an Osteoid Osteoma of the Femoral Neck Treated with Percutaneous Procedure Under Computed Tomography Guidance. (2016)
  • Author(s): Anazawa U, Watanabe I, Mizuno S and Hotta H.
  • Journal Title: Chemo Open Access Volume: 5(4)
  • Peer Reviewed / Open Access
• [Journal Article] Clinicopathological effects of protein phosphatase 2, regulatory subunit A, alpha mutations in gastrointestinal stromal tumors (2016)
  • Author(s): Ishii M, Akaike K, Suehara Y, Mukaihara K, Kubota K , Kohsaka S, Okubo T, Mitani K, Mogushi K, Takagi T, Kaneko K, Yao T, Saito T.
  • Journal Title: Modern Pathology. Volume: 29 Issue: 11 Pages: 1424-1432
  • DOI: 10.1038/modpathol.2016.138
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults (2016)
  • Author(s): Takahiko Yasuda, Shinobu Tsuzuki, Masahito Kawazu, Fumihiko Hayakawa, Shinya Kojima, Toshihide Ueno, Naoto Imoto, Shinji Kohsaka, Akiko Kunita, Koichiro Doi, Toru Sakura, Toshiaki Yujiri, Eisei Kondo, Katsumichi Fujimaki, Yasunori Ueda, Yasutaka Aoyama, Shigeki Ohtake, Junko Takita, Eirin Sai, Masafumi Taniwaki, et al.
  • Journal Title: Nature genetics Volume: in press Issue: 5 Pages: 409-417
  • DOI: 10.1038/ng.3535
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer. (2016)
  • Author(s): Takanobu Jotatsu, Shigehiro Yagishita, Ken Tajima, Fumiyuki Takahashi, Kaoru Mogushi, Moulid Hidayat, Aditya Wirawan, Ryo Ko, Ryota Kanemaru, Naoko Shimada, Keiko Mitani, Tsuyoshi Saito, Kazuya Takamochi, Kenji Suzuki, Shinji Kohsaka, Shinya Kojima, Hiroshi Mukae, Kazuhiro Yatera, Kazuhisa Takahashi.
  • Journal Title: Biochemistry and Biophysics Reports Volume: 9 Pages: 86-94
  • Peer Reviewed / Open Access
• [Journal Article] Real-time in vivo confocal fluorescence imaging of prostate cancer bone-marrow micrometastasis development at the cellular level in nude mice (2016)
  • Author(s): Miwa S, Toneri M, Igarashi K, Yano S, Kimura H, Hayashi K, Yamamoto N, Tsuchiya H, Hoffman RM
  • Journal Title: J Cell Biochem Volume: 117 Issue: 11 Pages: 2533-2537
  • DOI: 10.1002/jcb.25545
  • Peer Reviewed / Open Access
• [Journal Article] Clinical relevance of peroxisome proliferator-activated receptor-gamma expression in myxoid liposarcoma (2016)
  • Author(s): Takeuchi A, Yamamoto N, Shirai T, Hayashi K, Miwa S, Munesue S, Yamamoto Y, Tsuchiya H
  • Journal Title: BMC Cancer Volume: 16 Issue: 1 Pages: 442-442
  • DOI: 10.1186/s12885-016-2524-6
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Tenosynovial giant cell tumors in unusual locations detected by positron emission tomography imaging confused with malignant tumors: report of two cases (2016)
  • Author(s): Takeuchi A, Yamamoto N, Hayashi K, Miwa S, Takahira M, Fukui K, Oikawa T, Tsuchiya H
  • Journal Title: BMC Musculoskelet Disord Volume: 17 Issue: 1 Pages: 180-180
  • DOI: 10.1186/s12891-016-1050-7
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] OVarCall: bayesian mutation calling method utilizing overlapping paired-end reads (2016)
  • Author(s): Moriyama T, Shiraishi Y, Chiba K, Yamaguchi R, Imoto S, Miyano S
  • Journal Title: IEEE Trans Nanobioscience Volume: 14 Issue: 2 Pages: 1-6
  • DOI: 10.1109/tnb.2017.2670601
  • Peer Reviewed / Open Access
• [Journal Article] Ablation of MCL1 expression by virally induced microRNA-29 reverses chemoresistance in human osteosarcomas. (2016)
  • Author(s): Osaki S, Tazawa H, Hasei J, Yamakawa Y, Omori T, Sugiu K, Komatsubara T, Fujiwara T, Sasaki T, Kunisada T,
  • Journal Title: Sci Rep. Volume: 30(6) Issue: 1 Pages: 28953-28953
  • DOI: 10.1038/srep28953
  • Peer Reviewed / Open Access
• [Journal Article] Neurological Recovery after Posterior Spinal Surgery in Patients with Metastatic Epidural Spinal Cord Compression. (2016)
  • Author(s): Watanabe N, Sugimoto Y, Tanaka M, Mazaki T, Arataki S, Takigawa T, Kataoka M,&nbsp;Kunisada T, Ozaki T.
  • Journal Title: Acta Med Okayama. Volume: 70 Pages: 449-453
  • NAID: 120005971539
  • Peer Reviewed
• [Journal Article] Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors (2016)
  • Author(s): C.D. Middlebrooks, A.R. Banday, K. Matsuda, K.I. Udquim, O.O. Onabajo, A. Paquin, J.D. Figueroa, B. Zhu, S. Koutros, M. Kubo, T. Shuin, N.D. Freedman, M. Kogevinas, N. Malats, S.J. Chanock, M. Garcia-Closas, D.T. Silverman, N. Rothman, L. Prokunina-Olsson
  • Journal Title: Nature Genetics Volume: 48 Issue: 11 Pages: 1330-1338
  • DOI: 10.1038/ng.3670
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Feasibility and efficacy of gemcitabine and docetaxel combination chemotherapy for bone and soft tissue sarcomas: multi-institutional retrospective analysis of 134 patients. (2016)
  • Author(s): Tanaka K, Joyama S, Chuman H, Hiraga H, Morioka H, Yoshikawa H, Hosaka M, Takahashi M, Kubo T, Hatano H, Kaya M, Toguchida J, Nishida Y, Nagano A, Tsumura H, Iwamoto Y.
  • Journal Title: World J Surg Oncol. Volume: 8;14(1) Issue: 1 Pages: 306-314
  • DOI: 10.1186/s12957-016-1059-2
  • NAID: 120005997852
  • Peer Reviewed
• [Journal Article] Potential of boron neutron capture therapy (BNCT) for malignant peripheral nerve sheath tumors (MPNST) (2015)
  • Author(s): Fujimoto T., Andoh T., Sudo T., Fujita I., Fukase N., Takeuchi T., Sonobe H., Inoue M., Hirose T., Sakuma T., Moritake H., Sugimoto T., Kawamoto T., Fukumori Y., Yamamoto S., Atagi S., Sakurai Y., Kurosaka M., Ono K., Ichikawa H., Suzuki M.
  • Journal Title: Appl Radiat Isot. Volume: 106 Pages: 220-225
  • DOI: 10.1016/j.apradiso.2015.07.059
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] 疾患バイオバンクと分子疫学研究 (2020)
  • Author(s): 松田浩一
  • Organizer: がん予防学術大会 2020米子
  • Invited
• [Presentation] Japanese Sarcoma Genome Consortium (2020)
  • Author(s): Koichi Matsuda
  • Organizer: 79th Annual meeting of the Japanese Cancer Association
  • Invited
• [Presentation] Biobank of common and rare diseases in Japan (2020)
  • Author(s): Koichi Matsuda
  • Organizer: ISPCM2020
  • Invited
• [Presentation] 骨軟部腫瘍ゲノムコンソーシアムによるゲノム解析 (2020)
  • Author(s): 松田浩一
  • Organizer: 第140回 西日本整形・災害外科学会学術集会
  • Invited
• [Presentation] 骨軟部腫瘍のゲノム解析 (2020)
  • Author(s): 松田浩一
  • Organizer: 遺伝子セミナー 骨軟部腫瘍のゲノム解析
  • Invited
• [Presentation] 骨軟部腫瘍ゲノムコンソーシアム (2020)
  • Author(s): 松田浩一
  • Organizer: 第15回がんトランスレーショナルリサーチ（TR）ワークショップ
  • Invited
• [Presentation] 疾患バイオバンクとがんゲノム研究 (2019)
  • Author(s): 松田浩一
  • Organizer: 第69回日本電気泳動学会シンポジウム
  • Invited
• [Presentation] 疾患バイオバンクとがんゲノム研究 (2019)
  • Author(s): 松田浩一
  • Organizer: 第26回 東北地区骨軟部腫瘍研究会
  • Invited
• [Presentation] 骨軟部腫瘍ゲノムコンソーシアムにおけるゲノム解析 (2019)
  • Author(s): 松田浩一
  • Organizer: 第4回 日本肉腫学会 学術シンポジウム
  • Invited
• [Presentation] New immunomarkers for liposarcoma and its mimics. (2018)
  • Author(s): Yoshinao Oda.
  • Organizer: 107th Annual Meeting of USCAP (Invited lecture)
  • Int'l Joint Research / Invited
• [Presentation] Multi-Omics analysis of tumor suppressor p53 signaling pathway (2018)
  • Author(s): Koichi Matsuda
  • Organizer: Program IARI symposium CRCL
  • Int'l Joint Research / Invited
• [Presentation] 淡明細胞肉腫に対するEribulin mesilateの抗腫瘍効果 (2017)
  • Author(s): 中井翔、吉川秀樹他
  • Organizer: 第32回日本整形外科学会基礎学術集会
• [Presentation] Anti-tumor effects of Eribulin mesilate on clear cell sarcoma cell line. (2017)
  • Author(s): Nakai, S., Yoshikawa, H., et al.
  • Organizer: Annual Meeting of the Connective Tissue Oncology Society (CTOS)
  • Int'l Joint Research
• [Presentation] Clinical outcomes and management of nodal metastasis in the patients with epithelioid sarcoma. (2017)
  • Author(s): Outani, H., Yoshikawa, H., et al.
  • Organizer: Annual Meeting of the Connective Tissue Oncology Society (CTOS)
  • Int'l Joint Research
• [Presentation] シンポジウム：軟部肉種の分子病理学的解析と治療への応用 (2017)
  • Author(s): 小田義直、山元英崇、孝橋賢一、山田裕一
  • Organizer: 第50回日本整形外科学会骨・軟部腫瘍学術集会,2017.7.13-14(7.13),東京
• [Presentation] 教育講演：軟部腫瘍のWHO分類と新たな疾患概念 (2017)
  • Author(s): 小田義直
  • Organizer: 第56回日本臨床細胞学会総会秋期大会,2017.11.18-19(11.18),福岡
• [Presentation] SMARCB1(BAF47)欠損腫瘍における発がん性SWI/SNF(BAF)複合体のプロテオーム解析 (2017)
  • Author(s): 中山ロバート
  • Organizer: 日本癌学会
• [Presentation] SMARCB1の欠損はSW1/SNF複合体のクロマチンへの結合を不安定化させる (2017)
  • Author(s): 中山ロバート
  • Organizer: 日本整形外科学会骨・軟部腫瘍学術集会
• [Presentation] Cancer susceptible germline variants and their applications for precision medicine (2017)
  • Author(s): Koichi Matsuda
  • Organizer: The 1st International Conference for Precision Cancer Medicine（ICPC2017）
  • Int'l Joint Research / Invited
• [Presentation] 骨・軟部腫瘍領域でのエビデンス構築に向けた日本臨床腫瘍研究グループの取り組み (2016)
  • Author(s): 平賀博明、田仲和宏,中馬広一、森岡秀夫、松峯昭彦、戸口田淳也、永野昭仁、米本司、西田佳弘、福田治彦、岩本幸英
  • Organizer: 第89回日本整形外科学会学術総会
  • Place of Presentation: パシフィコ横浜（神奈川県・横浜市）
  • Year and Date: 2016-05-12
• [Presentation] 骨・軟部悪性腫瘍患者における症候性静脈血栓塞栓症発症のリスクファクター -骨軟部肉腫治療研究会(JMOG)前向き観察研究- (2016)
  • Author(s): 岩田慎太郎、米本司、川井章、平賀博明、外堀司、秋山達、角永茂樹、篠田裕介、末原義之、綿貫宗則、上田孝文
  • Organizer: 第89回日本整形外科学会学術総会
  • Place of Presentation: パシフィコ横浜（神奈川県・横浜市）
  • Year and Date: 2016-05-12
• [Presentation] 骨肉腫における予後予測ノモグラムの開発と外的妥当性の検証 (2016)
  • Author(s): 小倉浩一、藤原智洋、康永秀生、松居宏樹、JeonDae-Geun,平賀博明、石井猛、米本司、鴨田博人、尾崎敏文、小澤栄史、西田佳弘、森岡秀夫、比留間徹、角永茂樹、上田孝文、荒木信人、中紀文、津田祐輔、河野博隆、川井章
  • Organizer: 第89回日本整形外科学会学術総会
  • Place of Presentation: パシフィコ横浜（神奈川県・横浜市）
  • Year and Date: 2016-05-12
• [Presentation] Establishment of Japanese Sarcoma Genome Consortium (JSGC) for Genomic Analysis (2016)
  • Author(s): Koichi Matsuda and Japan Sarcoma Genome Consortium
  • Organizer: 11th APMSTS Meeting
  • Place of Presentation: シンガポール（シンガボール）
  • Int'l Joint Research / Invited
• [Presentation] 骨軟部腫瘍ゲノムコンソーシアムによる 共同研究体制の構築 (2016)
  • Author(s): 松田 浩一、骨軟部腫瘍ゲノムコンソーシアム
  • Organizer: 日本整形外科学会学術総会
  • Place of Presentation: パシフィコ横浜（神奈川県・横浜市）
  • Invited
• [Presentation] 骨軟部腫瘍ゲノムコンソーシアムを通じた ゲノム研究 ネットワークの構築 (2016)
  • Author(s): 松田 浩一、骨軟部腫瘍ゲノムコンソーシアム
  • Organizer: 第 49 回日本整形外科学会 骨・軟部腫瘍学術集会
  • Place of Presentation: 東京ドームホテル（東京都・文京区）
  • Invited
• [Presentation] 骨軟部腫瘍ゲノムコンソーシアムを通じた ゲノム研究 ネットワークの構築 (2016)
  • Author(s): 松田 浩一、骨軟部腫瘍ゲノムコンソーシアム
  • Organizer: 第 14 回日本臨床腫瘍学会学術集会
  • Place of Presentation: 神戸国際会議場（兵庫県・神戸市）
  • Invited
• [Presentation] 次世代ＤＮＡシークエンスによるがんの個別化医療の可能性 (2016)
  • Author(s): 松田浩一
  • Organizer: がん治療学会
  • Place of Presentation: パシフィコ横浜（神奈川県・横浜市）
  • Invited