| Budget Amount *help |
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2019: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2018: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2017: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2016: ¥11,050,000 (Direct Cost: ¥8,500,000、Indirect Cost: ¥2,550,000)
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| Outline of Final Research Achievements |
A voltammetric-localized surface plasmon resonance (V-LSPR) fiber optic sensor was develped. This sensor is constituted by indium tin oxide (ITO)-coated multimode fiber optic and gold nanoparticles. We demonstrated two types of sensing method which are based on a shift of LSPR peak wavelength accompanying the electrochemical oxidation & reduction of an analyte, and potential-scanning for detection of refractive index changing. For the first technique, Ru(NH3)62+/3+, methylene blue and Fe(CN)63-/4- were used as model analytes. The optical responses caused by the electrochemical reaction of the analytes showed linear relationship between LSPR peak shift and these concentrations. The second sensing was based on the detection of the LSPR peak potential during the potential-scanning, which shifts with refractive index changing in the solution. The developed sensor was successfully applied to the bio-detection of neutravidin by using a avidin-biotin interaction on the sensor surface.
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