Budget Amount *help |
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2019: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2018: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2017: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
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Outline of Final Research Achievements |
To clarify the dietary factors and their mechanisms that contribute to the progression and prevention of age-related hearing loss, we performed a series of experiments using mouse models. It was revealed that the hardness of the diet and the nutritional components influence the progression of long-term age-related hearing loss. In addition, transient hearing loss due to loud noise could be reduced by food components such as rosmarinic acid. We also obtained novel insights into gene expression changes associated with the progression of hearing loss.
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