| Budget Amount *help |
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2019: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2018: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
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| Outline of Final Research Achievements |
We are injecting organ progenitor cells into the organogenic niche of the stage-matched developing embryo and inducing differentiation into each organ lineage by executing the program of early organ development. It was confirmed that this method can also be applied to nephron progenitor cells derived from iPS cells of dialysis patient. In addition, we used a marmoset to enlarge the regenerated kidney. However, it was found that New World monkeys cannot control xeno- antigens by increasing the amount of conventional immunosuppressive agents, so it is necessary to carry out verification experiments by using Old World monkeys.
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