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Developments of high-intensity intermittent training under hypoxic conditions for improving cardiovascular and metabolic risk maker

Research Project

Project/Area Number 16H03234
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Sports science
Research InstitutionNational Institute of Fitness and Sports in Kanoya

Principal Investigator

OGITA Futoshi  鹿屋体育大学, スポーツ生命科学系, 教授 (50224134)

Co-Investigator(Kenkyū-buntansha) 添嶋 裕嗣  鹿屋体育大学, スポーツ生命科学系, 教授 (00295239)
片山 敬章  名古屋大学, 総合保健体育科学センター, 教授 (40343214)
後藤 一成  立命館大学, スポーツ健康科学部, 教授 (60508258)
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000)
Fiscal Year 2018: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2017: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2016: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Keywordsトレーニング科学 / 高強度間欠的運動トレーニング / 低酸素環境 / メタボリック症候群 / メタボリックシンドローム / 高強度トレーニング
Outline of Final Research Achievements

The present study aimed to clarify the effects of various high-intensity intermittent training (HIIT) under hypoxic conditions on cardiovascular and metabolic risk makers. In this study, 4 types of HIIT were done under 2500m above sea level. Those protocols were as follows; 1) six 10s-bout at 220%VO2max with 10s rest, 2) ten 20s-bout at 150%VO2max with 40s rest, 3)ten 1min-bout at 100%VO2max x 10 with 1min rest, 4) six or exhaustive 15s-bout at 175%VO2max with 10s rest. Each training was done 4 days a week for 4 weeks. As the results, HIIT (Tr.1 to 3) that the subjects did not reach exhaustion did not improve any factors, but that exhaustive HIIT (Tr.4) improved significantly cardiovascular function and body composition. Our results suggest that it is very beneficial and effective to perform exhaustive HIIT to improve effectively cardiovascular and metabolic risk factors. In other words, inexhaustive HIIT would be less effective even though it is done under hypoxic conditions.

Academic Significance and Societal Importance of the Research Achievements

本研究では、メタボリック症候群の危険因子改善をねらいとして、高強度間欠的低酸素トレーニングの効果を検証した。その結果、低酸素環境下における高強度運動であっても、疲労困憊に至らないプロトコールでは効果が乏しいということが示唆された。ネガティブデータであり、そのメカニズムについても明らかではないが、この点は学術的意義が深い。また、疲労困憊に至る運動に限れば、酸素レベルに関係なく効果が得られやすいこと、さらに循環応答、身体組成の改善には低酸素刺激がより効果的であることが示され、時間効率の良い運動処方を新たに例示できたことは社会的に意義が大きいと思われる。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • Research Products

    (28 results)

All 2018 2017 2016

All Journal Article (9 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 9 results,  Open Access: 6 results,  Acknowledgement Compliant: 1 results) Presentation (19 results) (of which Int'l Joint Research: 7 results,  Invited: 7 results)

  • [Journal Article] Effects of streptomycin administration on increases in skeletal muscle fiber permeability and size following eccentric muscle contractions.2018

    • Author(s)
      Hayao K., Tamaki H., Nakagawa K., Tamakoshi K., Takahashi H., Yotani K., Ogita F., Yamamoto N., Onishi H.
    • Journal Title

      Anat. Rec.

      Volume: 301 Issue: 6 Pages: 1096-1102

    • DOI

      10.1002/ar.23770

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Within-Day Amino Acid Intakes and Nitrogen Balance in Male Collegiate Swimmers during the General Preparation Phase2018

    • Author(s)
      Matsuda Takeshi、Kato Hiroyuki、Suzuki Haruka、Mizugaki Ami、Ezaki Takahiko、Ogita Futoshi
    • Journal Title

      Nutrients

      Volume: 10 Issue: 11 Pages: 1809-1809

    • DOI

      10.3390/nu10111809

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparison of carbohydrate metabolism between land and aquatic exercise following glucose ingestion2018

    • Author(s)
      Kurobe,K., A.Kousaka, F.Ogita, N.Matsumoto.
    • Journal Title

      Clin. Physiol.Funct Imaging

      Volume: 38 Pages: 227-232

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Effects of streptomycin administration on increases in skeletal muscle fiber permeability and size following eccentric muscles2018

    • Author(s)
      Hayao,K., H.Tamaki, K.Nakagawa, K.Tamakoshi, H.Takahashi, K.Yotani, F.Ogita, N.Yamamoto, H.Onishi
    • Journal Title

      Anat.Rec.

      Volume: -

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Electrical stimulation of denervated rat skeletal muscle ameliorates bone fragility and muscle loss in early-stage disuse musculoskeletal atrophy2017

    • Author(s)
      Tamaki H, Yotani K, Ogita F, Hayao K, Nakagawa K, Sugawara K, Kirimoto H, Onishi H, Kasuga N, Yamamoto N
    • Journal Title

      Calcif Tissue Int

      Volume: 100 Issue: 4 Pages: 420-430

    • DOI

      10.1007/s00223-017-0250-y

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Electrical stimulation of denervated rat skeletal muscle retards capillary and muscle loss in early stages of disuse atrophy2017

    • Author(s)
      Nakagawa,K, H.Tamaki, K.Hayao, K.Yotani, F.Ogita, N.Yamamoto, H.Onishi.
    • Journal Title

      BioMed Research International

      Volume: 未定 Pages: 5695217-5695217

    • DOI

      10.1155/2017/5695217

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Beneficial effects of hypoxic exercise on cardiovascular and metabolic risk markers.2017

    • Author(s)
      Ogita,F.
    • Journal Title

      Adapt.Med.

      Volume: 9 Pages: 114-118

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of carbohydrate metabolism between land and aquatic exercise following glucose ingestion2017

    • Author(s)
      Kurobe,K., A.Kousaka, F.Ogita, N.Matsumoto
    • Journal Title

      Clin. Physiol. Funct. Imaging

      Volume: 未定

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] he effects of exercise training under mild hypoxic conditions on body composition and circulating adiponectin in postmenopausal women2016

    • Author(s)
      Nishiwaki,M., R.Kakami, K.Saito, H.Tamaki, F.Ogita
    • Journal Title

      Clin. Physiol. Funct. Imaging

      Volume: 36 Issue: 6 Pages: 468-475

    • DOI

      10.1111/cpf.12252

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Effects of moderate-intensity endurance and high-intensity interval training under hypoxic conditions on metabolic risk markers2018

    • Author(s)
      Ogita,F., K.Yotani, H.Tamaki.
    • Organizer
      23th Annual Congress of European College of Sport Science
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 水中運動と陸上運動の違いから考える水泳選手の栄養戦略ーエネルギー代謝を中心としてー2018

    • Author(s)
      荻田太
    • Organizer
      日本スポーツ栄養学会第5回大会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 低圧低酸素環境下での100%VO2max強度における間欠的運動が血圧と動脈スティフネスに及ぼす影響2018

    • Author(s)
      荻田 太,與谷謙吾,田巻弘之
    • Organizer
      第26回日本運動生理学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 低圧低酸素環境下での100%VO2max強度における間欠的運動が耐糖能、血中脂質、身体組成に及ぼす影響2018

    • Author(s)
      荻田 太,大和谷健太,與谷謙吾,田巻弘之
    • Organizer
      第73回日本体力医学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 下肢自重負荷トレーニングによる起立性低血圧の改善効果2018

    • Author(s)
      中山貴文,坂本将基,荻田太,井福裕俊
    • Organizer
      第73回日本体力医学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Physiological adaptations to high-intensity exercise training2018

    • Author(s)
      Ogita,F.
    • Organizer
      TaiSPO 2018 Fitness Trend Seminar
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Effects of cycling exercise and aquatic exercise in hypobaric hypoxia on vascular adaptations and glucose tolerance2017

    • Author(s)
      Ogita,F., K.Yotani, K.Goto, K.Katayama, H.Tamaki.
    • Organizer
      22th Annual Congress of European College of Sport Science
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The effect of repeated bouts on sarcolemmal permeability and muscle force production after eccentric contractions in rat skeletal muscle2017

    • Author(s)
      Hayao,K., H.Tamaki, K.Nakagawa, K.Yotani, K., F.Ogita, K.Tamakoshi, H.Takahashi, H.Onishi, N.Yamamoto, N.Kasuga
    • Organizer
      22th Annual Congress of European College of Sport Science
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 不動初期の高齢ラットに対する電気刺激誘発性筋収縮が脛骨骨幹部の機械的特性に及ぼす影響2017

    • Author(s)
      田巻弘之,高橋英明,玉越敬悟,與谷謙吾,荻田太
    • Organizer
      第25回日本運動生理学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 低圧低酸素環境下における短期間の高強度間欠的運動が血圧と動脈スティフネスに及ぼす影響2017

    • Author(s)
      荻田 太,與谷謙吾,田巻弘之
    • Organizer
      第25回日本運動生理学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 低圧低酸素環境下における短時間高強度間欠的運動が耐糖能、血中脂質、身体組成に及ぼす影響2017

    • Author(s)
      荻田 太,與谷謙吾,田巻弘之
    • Organizer
      第72回日本体力医学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 起立性低血圧者における立位時の血圧調節2017

    • Author(s)
      中山貴文,坂本将基,荻田太,井福裕俊
    • Organizer
      第72回日本体力医学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Beneficial effects of hypoxic exercise on cardiovascular and metabolic risk markers2017

    • Author(s)
      Ogita,F
    • Organizer
      Eighth Cross-Strait Symposium oh Hypoxia and Dietetics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 低酸素環境下での運動トレーニングがもたらす効果2017

    • Author(s)
      荻田太
    • Organizer
      第21回酸素ダイナミクス研究会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 低酸素における生理学的メカニズムについて2017

    • Author(s)
      荻田太
    • Organizer
      第20回高所トレーニング国際シンポジウム
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Effects of high-intensity training on physiological adaptations and exercise performance -Additional effects of hypoxia-2016

    • Author(s)
      Ogita,F.
    • Organizer
      2016 Sport Science Seminar
    • Place of Presentation
      Taipei (Taiwan)
    • Year and Date
      2016-10-24
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] High intensity intermittent training: Benefits on physical performance and obesity-related metabolic health2016

    • Author(s)
      Ogita,F.
    • Organizer
      Joint Conference of Taiwan Society for Sports Nutrition and Chinese Taipei Association for the Study of Obesity
    • Place of Presentation
      Taipei (Taiwan)
    • Year and Date
      2016-10-23
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 下肢不動にした脛骨骨幹端骨梁における類骨形成に及ぼす電気刺激誘発生筋収縮の効果2016

    • Author(s)
      田巻弘之,與谷謙吾,荻田太,桐本光,大西秀明,山本智章,春日規克
    • Organizer
      第71回日本体力医学会大会
    • Place of Presentation
      いわて県民情報交流センター(岩手県・盛岡市)
    • Year and Date
      2016-09-23
    • Related Report
      2016 Annual Research Report
  • [Presentation] 低圧環境下で行う運動のタイプが糖処理能、血中脂質、身体組成に与える影響2016

    • Author(s)
      荻田太,黒部一道,黄忠,與谷謙吾,田巻弘之
    • Organizer
      第71回日本体力医学会大会
    • Place of Presentation
      いわて県民情報交流センター(岩手県・盛岡市)
    • Year and Date
      2016-09-23
    • Related Report
      2016 Annual Research Report

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Published: 2016-04-21   Modified: 2020-03-30  

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