| Budget Amount *help |
¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000)
Fiscal Year 2018: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2017: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2016: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
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| Outline of Final Research Achievements |
In the last decade, there has been great progress in technologies for the remote control of organisms through physical and chemical manipulation. In particular, methods involving lasers have proven useful for the control of biological functions in living organisms through simple manipulation with laser beams. Ultraviolet, short-wavelength visible, and infrared light are generally used in optical techniques for the control of biological functions in organisms. However, these types of light do not efficiently penetrate biological tissues. It is well known that near-infrared (NIR) rays can penetrate tissues because biological systems are relatively transparent to these wavelengths of light. We have developed NIR-laser-driven nanocomplexes for remote control of cellular functions. I believe that the technologies will help to create a new state-of-the-art tool for the comprehensive analysis of "real" biological molecular information at the single-cell level.
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