| Budget Amount *help |
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2019: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2018: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2017: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2016: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
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| Outline of Final Research Achievements |
The cell membrane is intimately involved in cell function by dynamically altering its membrane structure. The aim of this study was to control the dynamic structural changes of this membrane and its communication with cells based on the concept of membrane morphogenesis and its nanobiomedical applications. It was found that the elongation of lipid nanotubes, which function as a material and information transport system, can be controlled by physical stimulation by external fields or the addition of amphiphilic polymers as chemical stimuli. In addition, we established a system to control cellular functions such as differentiation by introducing extracellular vesicles as microvesicles into the cell with high efficiency in a magnetic field.
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