| Budget Amount *help |
¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2018: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2017: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Fiscal Year 2016: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
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| Outline of Final Research Achievements |
Atmospheric plasma is attracting interest for medical applications and clinical phases. We adduce the following questions to guide the future plasma medicine.
In this study, we explored the feasibility of using atmospheric microplasma irradiation to enhance percutaneous absorption of drugs, as an alternative delivery method to conventional hypodermic needles, to treat various symptoms, such as those associated with Alzheimer’s disease. Pig skin was used as a biological sample, exposed to microplasma irradiation, and analyzed by attenuated total reflection-Fourier transform infrared spectroscopy. The results show that the stratum corneum could be chemically and physically modified by microplasma irradiation. Physical damage to the skin by microplasma irradiation and plasma jets was also assessed by observing the skin surface. The results suggest that microplasma irradiation has the potential to enhance percutaneous absorption.
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