| Budget Amount *help |
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2020: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2019: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2018: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2017: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2016: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
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| Outline of Final Research Achievements |
We succeeded in the development of biphenyl derivatives as a new intramolecular CT photosensitizer on the basis of our own triplet-producing mechanism. We exploited this photosensitizer for the photodynamic damage of cancer cells. We also found that the biphenyl photosensitizer can be excited by two-photon excitation with a near-infrared laser, which enables deep-tissue entry. Overall, we have accomplished almost all the goals first planned, except for animal experiments.
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