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Development of ionic liquid based aqueous two-phase extraction

Research Project

Project/Area Number 16H04556
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Properties in chemical engineering process/Transfer operation/Unit operation
Research InstitutionDoshisha University

Principal Investigator

MATSUMOTO MICHIAKI  同志社大学, 理工学部, 教授 (10157381)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥13,520,000 (Direct Cost: ¥10,400,000、Indirect Cost: ¥3,120,000)
Fiscal Year 2018: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2017: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2016: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Keywordsイオン液体 / 水性2相 / 深共晶溶媒 / 分離 / 反応・分離工学 / 水性2相 / 抽出 / 液膜 / バイオマス
Outline of Final Research Achievements

Ionic liquids are attracting attention as new solvents because of their non-volatility, incombustibility and environmentally benign. On the other hand, ionic liquids are generally still expensive to use as commercial solvents because their purification is difficult. In this study, we investigated the function as a new separation medium of protic ionic liquid (PIL) and deep eutectic solvent (DES), which can express similar function to ionic liquid by mixing inexpensive substances. Of particular interest is the application of PIL and DES to aqueous two-phase extraction with low environmental impact. The main results obtained in this study, construction of a novel aqueous two-phase system using PIL and DES, and separation of bio-related compunds were achieved.

Academic Significance and Societal Importance of the Research Achievements

生体関連物質の工業的生産において分離プロセスは全コストの50%以上を占めるといわれ,環境負荷の小さくかつ経済的な分離システムを構築は喫緊の課題である.本研究ではこのために本研究では環境負荷の小さくかつ安価に合成できるプロトン性イオン液体や深共晶溶媒といった新規な溶媒を用いた新規水相2相系を用いた分離プロセスを提案し.ジオールやタンパク質の分離に有効であることを示した.

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • Research Products

    (34 results)

All 2018 2017 2016 Other

All Int'l Joint Research (1 results) Journal Article (12 results) (of which Peer Reviewed: 11 results,  Open Access: 6 results) Presentation (20 results) (of which Int'l Joint Research: 6 results) Book (1 results)

  • [Int'l Joint Research] Nusa Cendana University(インドネシア)

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Ionic Liquid–Based Liquid Membranes in Separation Technique2018

    • Author(s)
      松本道明
    • Journal Title

      MEMBRANE

      Volume: 43 Issue: 3 Pages: 88

    • DOI

      10.5360/membrane.43.88

    • NAID

      130007378557

    • ISSN
      0385-1036, 1884-6440
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Extraction and Esterification of Succinic Acid Using Aqueous Two-phase Systems Composed of Ethanol and Salts2018

    • Author(s)
      Michiaki Matsumoto, Masahiro Tatsumi
    • Journal Title

      Solvent Extraction Research and Development, Japan

      Volume: 25 Issue: 2 Pages: 101-107

    • DOI

      10.15261/serdj.25.101

    • NAID

      130006733830

    • ISSN
      1341-7215, 2188-4765
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] In situ extractive fermentation of lactic acid by Rhizopus oryzae in an air-lift bioreactor2018

    • Author(s)
      Michiaki Matsumoto, Hisanori Furuta
    • Journal Title

      Chemical and Biochemical Engineering Quarterly

      Volume: 32 Issue: 2 Pages: 275-280

    • DOI

      10.15255/cabeq.2017.1208

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enhanced activities and thermostability of lipase pretreated with carboxylic and perflurocarboxylic acids in transesterification2018

    • Author(s)
      Michiaki Matsumoto, Erika Matsui
    • Journal Title

      Journal of Chemical Technology & Biotechnology

      Volume: 93 Issue: 11 Pages: 3219-3222

    • DOI

      10.1002/jctb.5678

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Salting-out Extraction of 3-Hydroxypropionic Acid with Reactive Extraction and Aqueous Two-phase Systems2017

    • Author(s)
      Michiaki Matsumoto, Megumi Shibazaki, Ryo Yuasa, Kazuo Kondo
    • Journal Title

      Solvent Extraction Research and Development, Japan

      Volume: 24 Issue: 2 Pages: 141-147

    • DOI

      10.15261/serdj.24.141

    • NAID

      130005689401

    • ISSN
      1341-7215, 2188-4765
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Solvent extraction and stripping of Fe and Mn from aqueous solution using ionic liquids as extractants2017

    • Author(s)
      Pius Dore Ola, Yusuke Kurobe, Michiaki Matsumoto
    • Journal Title

      Chemical Engineering Transactions

      Volume: 57 Pages: 1135-1140

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Recovery of Fe and Mn from aqueous solution with solvent extraction and liquid membrane permeation using ionic liquids2017

    • Author(s)
      Pius Dore Ola, Michiaki Matsumoto, Kazuo Kondo
    • Journal Title

      Desalination and Water Treatment

      Volume: 75 Pages: 325-330

    • DOI

      10.5004/dwt.2017.20406

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Photocatalytic degradation of pentachlorophenol by TiO2 supported on mesoporous silica2017

    • Author(s)
      Michiaki Matsumoto, Shinsuke Usami
    • Journal Title

      Desalination and Water Treatment

      Volume: 80 Pages: 352-356

    • DOI

      10.5004/dwt.2017.21038

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of Quaternary Ammonium Salts on the Extraction of 1,3-Propanediol with Phenylboronic Acid2016

    • Author(s)
      Michiaki Matsumoto, Kikuko Shimizu, Yuji Harada and Kazuo Kondo
    • Journal Title

      Solvent Extraction Research and Development, Japan

      Volume: 23 Issue: 2 Pages: 175-180

    • DOI

      10.15261/serdj.23.175

    • NAID

      130005152885

    • ISSN
      1341-7215, 2188-4765
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Extractive fermentation of lactic acid with Hiochi bacteria in a two-liquid phase system2016

    • Author(s)
      Michiaki Matsumoto, Masashi Nishimura, Hiroaki Kobayashi and Kazuo Kondo
    • Journal Title

      Fermentation Technology

      Volume: 5 Issue: 2 Pages: 1000219-1000219

    • DOI

      10.4172/2167-7972.1000129

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Adsorption of ferrous ion in water on filter paper including cedar bark2016

    • Author(s)
      Michiaki Matsumoto, Akiyoshi Ikoma, Kazuo Kond
    • Journal Title

      Desalination and Water Treatment

      Volume: 57 Issue: 54 Pages: 26294-26298

    • DOI

      10.1080/19443994.2016.1170640

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 松本道明2016

    • Author(s)
      塩析・糖析を利用した分離技術の新展開
    • Journal Title

      日本海水学会誌

      Volume: 70 Pages: 354-357

    • Related Report
      2016 Annual Research Report
  • [Presentation] 3-ヒドロキシプロピオン酸の塩析抽出2018

    • Author(s)
      松本道明,柴崎愛実,湯浅亮
    • Organizer
      分離技術会年会2018
    • Related Report
      2018 Annual Research Report
  • [Presentation] イオン液体系水性2相系によるコバルトの抽出2018

    • Author(s)
      山口拓哉,松本道明
    • Organizer
      日本海水学会第69年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Extraction and stripping of manganese and cobalt from aqueous solution with deep eutectic solvent as extractants2018

    • Author(s)
      Pius Dore Ola, Yusuke Kurobe, Michiaki Matsumoto
    • Organizer
      The 7th International Conference on Ion Exchange
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] デカン酸とリドカインからなる深共融溶媒を用いた金属イオンの抽出2018

    • Author(s)
      Pius Dore Ola,松本道明
    • Organizer
      化学工学会第50回秋季大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Extraction of precious metals from aqueous solution with deep eutectic solvent as extractants2018

    • Author(s)
      Pius Dore Ola, Michiaki Matsumoto
    • Organizer
      The 1st International Conference and Exhibition on Science and Technology
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 疎水性プロトン性イオン液体を用いたマンガンおよび銅の抽出2018

    • Author(s)
      岡邊伯恭,松本道明
    • Organizer
      第37回溶媒抽出討論会
    • Related Report
      2018 Annual Research Report
  • [Presentation] プロトン性イオン液体を用いたタンパク質の水性二相抽出2018

    • Author(s)
      進士文也、松本道明
    • Organizer
      第37回溶媒抽出討論会
    • Related Report
      2018 Annual Research Report
  • [Presentation] DES/塩系水性2相系を用いた乳酸の抽出2018

    • Author(s)
      竹森彩恵,松本道明
    • Organizer
      第37回溶媒抽出討論会
    • Related Report
      2018 Annual Research Report
  • [Presentation] プロトン性イオン液体による木材からの多糖抽出2017

    • Author(s)
      吉田圭吾,松本道明,近藤和生
    • Organizer
      化学工学会第81年会
    • Place of Presentation
      芝浦工業大学(東京都江東区)
    • Year and Date
      2017-03-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] Extraction of protein with aqueous two-phase system using deep eutectic solvent ionic liquids including betaine2017

    • Author(s)
      M. Matsumoto, M. Tatsumi, K. Kondo
    • Organizer
      3rd International Conference on Ionic Liquids in Separation and Purification Technology
    • Place of Presentation
      クアラルンプール(マレーシア)
    • Year and Date
      2017-01-08
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 糖析を用いた水性2相による有機酸の抽出2017

    • Author(s)
      神垣達也,松本道明
    • Organizer
      分離技術会年会2017
    • Related Report
      2017 Annual Research Report
  • [Presentation] プロトン性イオン液体を用いた1,3-プロパンジオールの水性二相抽出2017

    • Author(s)
      進士文也,松本道明
    • Organizer
      分離技術会年会2017
    • Related Report
      2017 Annual Research Report
  • [Presentation] イオン液体系水性2相を用いた鉄・マンガンの抽出2017

    • Author(s)
      岡邊伯恭,松本道明
    • Organizer
      日本海水学会第68年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Extraction of ferric and manganese ions with aqueous two-phase system formed by ionic liquid and polyethylene glycol2017

    • Author(s)
      Pius Dore Ola, Noriyuki Okabe, Michiaki Matsumoto
    • Organizer
      The 21rd International Solvent Extraction Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Use of deep eutectic solvent as extractant for separation of Fe(III) and Mn(II) from aqueous solution2017

    • Author(s)
      Pius Dore Ola, Michiaki Matsumoto
    • Organizer
      The 24th Regional Symposium on Chemical Engineering 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] イオン液体および融点降下溶媒を用いたアルブミンの水性2相抽出2016

    • Author(s)
      辰巳正浩,松本道明,近藤和生
    • Organizer
      化学工学会福島大会
    • Place of Presentation
      コラッセ福島(福島県福島市)
    • Year and Date
      2016-11-25
    • Related Report
      2016 Annual Research Report
  • [Presentation] イオン液体含有高分子膜を用いたフェニルアラニンの透過2016

    • Author(s)
      井上 慧,松本道明,近藤和生
    • Organizer
      化学工学会第48回秋季大会
    • Place of Presentation
      徳島大学(徳島県徳島市)
    • Year and Date
      2016-09-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] エタノール-塩系水性2相によるコハク酸の抽出とエステル化2016

    • Author(s)
      辰巳正浩,松本道明,近藤和生
    • Organizer
      化学工学会第48回秋季大会
    • Place of Presentation
      徳島大学(徳島県徳島市)
    • Year and Date
      2016-09-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] イオン液体含有高分子膜を用いたトリプトファンの透過2016

    • Author(s)
      喜多宣竹,松本道明,近藤和生
    • Organizer
      分離技術会年会2016
    • Place of Presentation
      日本大学(千葉県習志野市)
    • Year and Date
      2016-05-27
    • Related Report
      2016 Annual Research Report
  • [Presentation] Recovery of Fe and Mn from aqueous solution using solvent extraction and liquid membrane permeation using ionic liquids2016

    • Author(s)
      Pius Dore Ola, Michiaki Matsumoto, Kazuo Kondo
    • Organizer
      Membrane Science and Technology Conference of Visegrad Contries 2016 and Membrane and Electromembrane Processes 2016
    • Place of Presentation
      プラハ(チェコ)
    • Year and Date
      2016-05-15
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Book] "Metal Extraction with Ionic Liquids-Based Aqueous Two-Phase System" in Recent Advances in Ionic Liquids2018

    • Author(s)
      Pius Dore Ola, Michiaki Matsumoto
    • Total Pages
      14
    • Publisher
      InTech
    • ISBN
      9781789841183
    • Related Report
      2018 Annual Research Report

URL: 

Published: 2016-04-21   Modified: 2020-03-30  

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