| Budget Amount *help |
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2018: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2017: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2016: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
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| Outline of Final Research Achievements |
In vivo, a series of enzymes are closely packed in a minute space, and the enzyme reactions are coupled. In this study, enzymes are clustered on nanoparticles and the clustered enzymes are hierarchically assembled to reconstruct in-vivo-mimic enzyme-crowded environment. The utilization of material-binding peptides and proteins showed the possibility for spontaneous self-assembly of clustered enzymes.
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