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Novel approach of the surface functionalization of nanomaterials based on noncovalent chemistry

Research Project

Project/Area Number 16H04577
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Biofunction/Bioprocess
Research InstitutionKobe University

Principal Investigator

Maruyama Tatsuo  神戸大学, 工学研究科, 教授 (30346811)

Co-Investigator(Kenkyū-buntansha) 田中 勉  神戸大学, 工学研究科, 准教授 (90436551)
Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2019: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2018: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2017: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
Keywordsナノ材料 / 界面活性剤 / 重合 / 生体分子 / 分散状態 / 表面修飾 / 表面機能化 / 高分子 / 表面 / 機能化 / ポリマー / ナノマテリアル / 親溶媒化 / 分散 / 界面 / ナノ粒子 / 有機無機ハイブリッド / 高分子重合 / 表面改質 / ナノバイオ
Outline of Final Research Achievements

In this study, we aimed to develop polymerizable surfactants, which lead to stable surface functionalization. One of the polymerizable surfactants we synthesized was designed and synthesized to consist of a methacryloyl group, oligo(ethylene glycol) and a long alkyl group. The surfactant assisted the dispersion of gold nanoparticles in water. The polymerization of the surfactant on the gold nanoparticles did not affect the dispersion. After the polymerization, the gold nanoparticles kept the well dispersion state in water. The dispersion was not affected by washing the nanoparticles or by diluting the dispersion. The polymerization of the surfactant was also achieved on carbon nanotubes and improved the dispersion of carbon nanotubes in water. The present approach based on the polymerizable surfactant successfully realized non-detachable surfactant and stable surface functionalization.

Academic Significance and Societal Importance of the Research Achievements

カーボンナノ材料や金属ナノ粒子は特有の光学的・熱・電気・磁気的性質や機械的特性をもつことから、機能性材料として広く注目を集めている。カーボンナノ材料や金属ナノ粒子表面は一般に強い疎溶媒性を示すため、成形加工等のハンドリング過程において溶媒中で凝集してしまうことや、反応点が限られているといった問題がある。これらナノ材料と他の材料を複合化させるためには、ナノ材料表面を修飾し、表面改質を行うことが必要である。本研究では界面活性剤をナノ材料表面で重合させることで剥がれない界面活性剤・剥がれない表面機能化を達成した。本方法は、材料表面の材質に依存しないため様々な材料に適用可能である。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • Research Products

    (29 results)

All 2020 2019 2018 2017 2016

All Journal Article (16 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 16 results,  Open Access: 2 results,  Acknowledgement Compliant: 4 results) Presentation (11 results) (of which Int'l Joint Research: 2 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Hydrogel formation by short D-peptide for cell-culture scaffolds2020

    • Author(s)
      Restu Witta Kartika、Yamamoto Shota、Nishida Yuki、Ienaga Hirotoshi、Aoi Takashi、Maruyama Tatsuo
    • Journal Title

      Materials Science and Engineering: C

      Volume: 111 Pages: 110746-110746

    • DOI

      10.1016/j.msec.2020.110746

    • NAID

      120006841709

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] One-Step Biotinylation of Cellulose Paper by Polymer Coating to Prepare a Paper-Based Analytical Device2019

    • Author(s)
      Kaneko Kazuki、Hara Manami、Nishino Takashi、Maruyama Tatsuo
    • Journal Title

      Analytical Chemistry

      Volume: 92 Issue: 2 Pages: 1978-1987

    • DOI

      10.1021/acs.analchem.9b04373

    • NAID

      120006811103

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Cu-free clickable surface with controllable surface density2019

    • Author(s)
      Miyahara Koki、Sakai Rika、Hara Manami、Maruyama Tatsuo
    • Journal Title

      Colloid and Polymer Science

      Volume: 297 Issue: 6 Pages: 927-931

    • DOI

      10.1007/s00396-019-04515-4

    • NAID

      120006709437

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quantification of azide groups on a material surface and a biomolecule using a clickable and cleavable fluorescent compound2019

    • Author(s)
      Rika Sakai, Hiroki Iguchi and Tatsuo Maruyama
    • Journal Title

      Rsc Advances

      Volume: 9 Issue: 8 Pages: 4621-4625

    • DOI

      10.1039/c8ra09421g

    • NAID

      120006599123

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Surface-functionalization of isotactic polypropylene via dip-coating with a methacrylate-based terpolymer containing perfluoroalkyl groups and poly(ethylene glycol)2019

    • Author(s)
      M. Hara, S. Kitahata, K. Nishimori, K. Miyahara, K. Tokuda, T. Nishino, T. Maruyama
    • Journal Title

      Polymer Journal

      Volume: 51 Issue: 5 Pages: 489-499

    • DOI

      10.1038/s41428-018-0164-1

    • NAID

      120006634672

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of uncurled and planar multilayered graphene using polythiophene derivatives via liquid-phase exfoliation of graphite2018

    • Author(s)
      H. Iguchi, K. Miyahara, C. Higashi, K. Fujita, N. Nakagawa, S. Tamba, A. Mori, H. Yoshitani, A. Nakasuga, T. Maruyama
    • Journal Title

      FlatChem

      Volume: 8 Pages: 31-39

    • DOI

      10.1016/j.flatc.2018.03.003

    • NAID

      120006502540

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Controlling Surface Segregation of a Polymer To Display Carboxy Groups on an Outermost Surface Using Perfluoroacyl Groups2018

    • Author(s)
      Keisuke Nishimori, Shigeru Kitahata, Takashi Nishino, Tatsuo Maruyama
    • Journal Title

      Langmuir

      Volume: 34 Issue: 22 Pages: 6396-6404

    • DOI

      10.1021/acs.langmuir.8b00638

    • NAID

      120006489848

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Short Oligopeptides for Biocompatible and Biodegradable Supramolecular Hydrogels2018

    • Author(s)
      Witta Kartika Restu, Yuki Nishida, Shota Yamamoto, Jun Ishii, Tatsuo Maruyama
    • Journal Title

      Langmuir

      Volume: 34 Issue: 27 Pages: 8065-8074

    • DOI

      10.1021/acs.langmuir.8b00362

    • NAID

      120006489849

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Electrospun polymeric short microfibers with surface-selective functionalization2018

    • Author(s)
      Tetsuya Matsuura, Eiko Tsuchiya, Yu Fukui, Tatsuo Maruyama
    • Journal Title

      Colloid Polym Sci

      Volume: 296 Issue: 1 Pages: 239-244

    • DOI

      10.1007/s00396-017-4235-1

    • NAID

      120006398789

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Palmitoylated amino acids as low-molecular-weight gelators for ionic liquids2017

    • Author(s)
      Restu Witta Kartika, Nishida Yuki,Kataoka Toshikazu, Morimoto Masahiro, Ishida Kenji, Mizuhata Minoru, Maruyama Tatsuo
    • Journal Title

      Colloid Polym Sci

      Volume: 295 Issue: 7 Pages: 1109-1116

    • DOI

      10.1007/s00396-017-4093-x

    • NAID

      120006363285

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] In Situ Synthesis of a Supramolecular Hydrogelator at an Oil/Water Interface for Stabilization and Stimuli-Induced Fusion of Microdroplets2017

    • Author(s)
      Yuki Nishida, Akiko Tanaka, Shota Yamamoto, Yudai Tominaga, Nobuaki Kunikata, Minoru Mizuhata, and Tatsuo Maruyama
    • Journal Title

      Angew. Chem. Int. Ed

      Volume: 56 Issue: 32 Pages: 9410-9414

    • DOI

      10.1002/anie.201704731

    • NAID

      120006363284

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Hollow phosphorylcholine polymer vesicles prepared by a coaxial electrospray technique2017

    • Author(s)
      Tetsuya Matsuura, Tatsuo Maruyama
    • Journal Title

      Colloid Polym Sci

      Volume: 295 Issue: 7 Pages: 1251-1256

    • DOI

      10.1007/s00396-017-4110-0

    • NAID

      120006363286

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Rational and practical exfoliation of graphite using well-defined poly(3-hexylthiophene) for the preparation of conductive polymer/graphene composite2017

    • Author(s)
      H. Iguchi, C. Higashi, Y. Funasaki, K. Fujita, A. Mori, A. Nakasuga, T. Maruyama
    • Journal Title

      Scientific reports

      Volume: 7 Issue: 1 Pages: 39937-39937

    • DOI

      10.1038/srep39937

    • NAID

      120005970763

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Calcium phosphate-polymer hybrid microparticles having functionalized surfaces prepared by a coaxially electrospray technique2017

    • Author(s)
      T. Matsuura, T. Maruyama
    • Journal Title

      Colloids and Surfaces A

      Volume: 印刷中 Pages: 64-69

    • DOI

      10.1016/j.colsurfa.2016.10.036

    • NAID

      120006363287

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] In-situ polymerization of a novel surfactant on graphene surface for the stable graphene dispersion in water2016

    • Author(s)
      C. Higashi, Y. Funasaki, H. Iguchi, and T. Maruyama
    • Journal Title

      RSC Advances

      Volume: 6 Issue: 91 Pages: 88244-88247

    • DOI

      10.1039/c6ra20315a

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Liquid-liquid extraction of enzymatically synthesized functional RNA oligonucleotides using reverse micelles with a DNA-surfactant2016

    • Author(s)
      T. Maruyama, N. Ishizu, Y. Eguchi, T. Hosogi, M. Goto
    • Journal Title

      Chemical communications

      Volume: 52 Issue: 83 Pages: 12376-12379

    • DOI

      10.1039/c6cc06985a

    • NAID

      120006318791

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] A clickable surfrace prepared by simple polymer coating2018

    • Author(s)
      K. Miyahara, R. Sakai, T. Maruyama
    • Organizer
      MACRO18 World Polymer Congress
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 塗るだけで機能を発現するポリプロピレンの表面修飾コーティング2018

    • Author(s)
      原 真奈美, 西森 圭亮, 北畑 繁, 西野 孝, 丸山 達生
    • Organizer
      第67回高分子学会年次大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] PEG系高分子の塗布によるセルロース紙表面機能化法の開発2018

    • Author(s)
      金子一貴, 原真奈美, 丸山 達生
    • Organizer
      化学工学会第20回化学工学会学生発表会
    • Related Report
      2018 Annual Research Report
  • [Presentation] ポリチオフェンを基本骨格とする導電性高分子を用いたグラフェン分散技術の開発2017

    • Author(s)
      井口 博貴、東 千誠、舟崎 裕一、藤田 佳佑、森 敦紀、中壽賀 章、丸山 達生
    • Organizer
      第66回高分子学会年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 含フッ素高分子と接着プライマーを用いたポリプロピレンの表面修飾法の開発2017

    • Author(s)
      原 真奈美、西森 圭亮、北畑 繁、西野 孝、丸山 達生
    • Organizer
      化学工学会第49回秋季大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] フッ素含有高分子の塗布によるプラスチック表面へのカルボキシ基の提示2017

    • Author(s)
      西森 圭亮、北畑 繁、下村 文音、西野 孝、丸山 達生
    • Organizer
      第66回高分子学会年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] urface modification of metal nanoparticles using a polymerizable surfactant2016

    • Author(s)
      東 千誠、舟崎 裕一、丸山 達生
    • Organizer
      The 11th SPSJ International Polymer Conference
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2016-12-16
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Modification of surfaces of metal nanoparticles using a polymerizable surfactant2016

    • Author(s)
      東 千誠、舟崎 裕一、丸山 達生
    • Organizer
      化学工学会第48回秋季大会
    • Place of Presentation
      徳島大学(徳島県・徳島市)
    • Year and Date
      2016-09-15
    • Related Report
      2016 Annual Research Report
  • [Presentation] 規重合性界面活性剤を用いた金属ナノ粒子の表面修飾法の開発2016

    • Author(s)
      東 千誠、舟崎 裕一、丸山 達生
    • Organizer
      第65回高分子討論会
    • Place of Presentation
      神奈川大学(神奈川県・横浜市)
    • Year and Date
      2016-09-15
    • Related Report
      2016 Annual Research Report
  • [Presentation] 重合性界面活性剤を用いた金属ナノ粒子の表面修飾法の開発2016

    • Author(s)
      東 千誠、舟崎 裕一、丸山 達生
    • Organizer
      第65回高分子学会年次大会
    • Place of Presentation
      神戸国際会議場・展示場(兵庫県・神戸市)
    • Year and Date
      2016-05-26
    • Related Report
      2016 Annual Research Report
  • [Presentation] 重合性界面活性剤による金属ナノ粒子表面の機能化2016

    • Author(s)
      東 千誠、舟崎 裕一、丸山 達生
    • Organizer
      第62回高分子研究発表会
    • Place of Presentation
      兵庫県民会館(兵庫県・神戸市)
    • Year and Date
      2016-05-15
    • Related Report
      2016 Annual Research Report
  • [Patent(Industrial Property Rights)] 機能性ポリオレフィン2018

    • Inventor(s)
      丸山達生ら
    • Industrial Property Rights Holder
      神戸大学、東洋紡
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-231032
    • Filing Date
      2018
    • Related Report
      2018 Annual Research Report
  • [Patent(Industrial Property Rights)] 高分散金属ナノ粒子およびその製造方法2017

    • Inventor(s)
      丸山達生、東千誠
    • Industrial Property Rights Holder
      丸山達生、東千誠
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-021438
    • Filing Date
      2017-02-08
    • Related Report
      2016 Annual Research Report

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Published: 2016-04-21   Modified: 2021-02-19  

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