| Budget Amount *help |
¥16,380,000 (Direct Cost: ¥12,600,000、Indirect Cost: ¥3,780,000)
Fiscal Year 2019: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2018: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2016: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
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| Outline of Final Research Achievements |
We morphologically analyzed synaptic inputs to the PV-expressing GABAergic neurons in various cortical areas. We found that the patterns of the inputs have different among cortical areas. In addition, we constructed a theoretical model of PV neurons and found that the locations of inhibitory inputs affected the synchronous activities of the circuits. Furthermore, we developed a new tissue-clearing method. The method enables us to clear the brain tissues in a short time without sample expansion and contraction. We also confirmed the method is compatible with electron microscopic observation.
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