| Budget Amount *help |
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2020: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2019: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2018: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2017: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
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| Outline of Final Research Achievements |
The plant cuticle covers aerial organs such as leaves, stem and floral organs, and plays essential roles in water retention, defense against pathogen, and prevention of organ fusion during their development. In the present research, we have utilized an Arabidopsis ABC transporter ABCG11, which is mainly expressed in epidermis and promote cuticle formation. According to the previous studies, ABCG11 localizes at the plasma membrane of the epidermal cells and export cuticle precursor. Therefore, it is plausible to speculate that localization of ABCG11 at the plasma membrane is a prerequisite for its functionality. In order to understand the mechanisms involved in intracellular trafficking of ABCG11, we have carried out screening for the sequence-based determinant for ABCG11 localization, and genetic screen for regulatory components involved in ABCG11 localization.
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