| Budget Amount *help |
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2019: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2018: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2017: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2016: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
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| Outline of Final Research Achievements |
Amphibians form their hands and feet by differential growth. It means that differences in the growth rate between the digital and interdigital regions will determine the final proportions of these structures. In contrast, amniotes employ interdigital cell death, an additional mechanism that contributes to a greater variation of limb shapes. In this study, we investigate the role of environmental oxygen in the evolution of interdigital cell death in tetrapods. In this study, we identified a surprising factor that could have been crucial for the appearance of interdigital cell death in tetrapods during evolution: the amount of oxygen surrounding the embryo.
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