| Budget Amount *help |
¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2020: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2019: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2018: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2017: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2016: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
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| Outline of Final Research Achievements |
Our previous studies showed that the viral "genome replication factories" formed
by a plant RNA virus in infected cells play important roles in both the replication of the viral genome and the transfer of the viral genomes from infected cells to adjacent cells. In this study, we tracked the transition of the factories over time. We found that the factories began to form as a large number of fine granular structures in the vicinity of the endoplasmic reticulum membrane, and eventually increased in size through repeated collisions and fusions, and finally grew to the same level as the nucleus. The viral replication enzyme protein continued to exist in the factories, while the movement protein that facilitates for the viral cell-to-cell movement, began to form as granular structures independent of the factories and fused with the factories over time.
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