| Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2018: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
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| Outline of Final Research Achievements |
In Aspergillus oryzae, isomaltose that is converted from maltose incorporated into the cell, is involved in the activation of the transcription factor AmyR, while in Aspergillus luchuensis and Aspergillus nidulans, isomaltose extracellularly converted from maltose is involved in AmyR activation, indicating that regulation mechanism for AmyR activation is different among these three Aspergillus fungi. In A. luchuensis, the acid-stable α-amylase is under the control of AmyR but not under the control of FlbC. The acid-unstable α-amylase, Taka-amylase ortholog, is constitutively produced, suggesting the existence of a different regulation from AmyR. The cis-element bound by the transcription factor FlbC could be identified by gel shift assay.
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