Budget Amount *help |
¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2018: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2017: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2016: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
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Outline of Final Research Achievements |
This study aims to clarify the interactions between the gut cell factors, including membrane proteins, glycoproteins and also glycolipids, and Bifdobacteral surface factors. 1) Construct Knockout mutant collection of Cell curface proteins and polysaccharides genes of Bifidobacterium. 2)Research the interaction between the animal cell-line of Intestinal epithelial cells and macrophage. Through these, we will clarify the correspondence between molecules involved in Bifidobacterium-cell interaction and the involvement in cell adhesion.
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