• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Pathogenic mechanism and control of soft egg disease in salmonids

Research Project

Project/Area Number 16H04964
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Aquatic bioproduction science
Research InstitutionHokkaido University

Principal Investigator

Kasai Hisae  北海道大学, 水産科学研究院, 准教授 (50399995)

Co-Investigator(Kenkyū-buntansha) 酒井 隆一  北海道大学, 水産科学研究院, 教授 (20265721)
Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2019: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2018: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2017: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Keywords卵膜軟化症 / サケ / シロサケ
Outline of Final Research Achievements

Soft egg disease in salmonids causes loss of firmness of the egg membrane, increasing vulnerability of the embryo to external impact. In this study, we show that the disease is caused when bacteria from the environment gradually dissolve the surface of the egg membrane. We analyzed bacteria attached to egg membranes, and found candidate pathogenic bacteria to be short bacilli. Artificial culture of the pathogen was possible and a specific detection method was subsequently developed. Furthermore, we demonstrate how polyphenols can inhibit egg membrane softening.

Academic Significance and Societal Importance of the Research Achievements

卵膜軟化症はサケの卵期の主な減耗要因であるが,発症原因および機構は解明されておらず,発症の程度を表す明確な指標も定められていない。本研究は,卵膜軟化症の発症原因の特定から科学的エビデンスに基づく防除法の確立まで体系立てて行ったものであり,本研究成果で得られた成果は疾病予防へとつながる基盤的な情報となる。サケ科魚類の増養殖による安定的な生産に重要かつ直接的な貢献をもたらすものであり,それらの学術的意義や社会的意義は極めて高い。

Report

(5 results)
  • 2020 Final Research Report ( PDF )
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • Research Products

    (9 results)

All 2021 2020 2018 2017 2016

All Journal Article (1 results) Presentation (8 results) (of which Int'l Joint Research: 1 results,  Invited: 2 results)

  • [Journal Article] サケ資源を安定的に維持するための防疫対策2018

    • Author(s)
      笠井久会,吉水 守
    • Journal Title

      日本水産学会誌

      Volume: 印刷中

    • Related Report
      2017 Annual Research Report
  • [Presentation] サケ(Oncorhynchus keta)における孵化酵素活性と孵化酵素遺伝子 発現量の消長および卵膜軟化症との関連性2021

    • Author(s)
      八木橋大亮・笠井久会
    • Organizer
      令和3年度日本魚病学会春季大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 卵膜軟化症発症卵の卵膜に付着する微生物群集の構造2020

    • Author(s)
      笠井久会・八木橋大亮・小松代祐生・西川恵介・鈴木健吾
    • Organizer
      令和2年度日本魚病学会春季大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] ポリフェノールとなめし剤によるサケ (Oncorhynchus keta) の卵膜軟化症予防効果2018

    • Author(s)
      工藤雅子・小松代祐生・記内 優・伴 真俊・笠井久会
    • Organizer
      平成30年度日本魚病学会秋季大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 卵膜軟化症発症時におけるサケ卵膜タンパク質の構造変化2018

    • Author(s)
      記内 優・小松代祐生・工藤雅子・伴 真俊・笠井久会
    • Organizer
      平成30年度日本魚病学会秋季大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] カテキンの構造がサケ (Oncorhynchus keta) の卵膜軟化症防除効果に与える影響2017

    • Author(s)
      小松代祐生,記内 優,松本善行,大久保 勉,伴 真俊,中山 勉,酒井隆一,笠井久会
    • Organizer
      平成29年度日本魚病学会春季大会
    • Place of Presentation
      日本大学(神奈川県藤沢市)
    • Year and Date
      2017-03-11
    • Related Report
      2016 Annual Research Report
  • [Presentation] Prevention of soft egg disease of chum salmon using green tea extract2016

    • Author(s)
      Kasai, H., Nishikawa, K., Ban, M. and Yoshimizu, M.
    • Organizer
      A.F.S. Fish Health Section Meeting
    • Place of Presentation
      Snow King Hotel, Jackson Hole, Wyoming, 米国
    • Year and Date
      2016-06-07
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] サケマス類の卵膜軟化症の原因と対策2016

    • Author(s)
      笠井久会,伴 真俊
    • Organizer
      平成28年度サケ学研究会
    • Place of Presentation
      北海道大学(北海道札幌市)
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] サケマス類の卵膜軟化症の原因と対策2016

    • Author(s)
      笠井久会,伴 真俊
    • Organizer
      平成28年度さけます報告会
    • Place of Presentation
      ホテルライフォート札幌(北海道札幌市)
    • Related Report
      2016 Annual Research Report
    • Invited

URL: 

Published: 2016-04-21   Modified: 2025-01-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi