| Budget Amount *help |
¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2019: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2018: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
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| Outline of Final Research Achievements |
Peptide sequences of gonadotropin releasing hormones (GnRHs), which are conserved among bivalves, was characterized in comparison with vertebrates. Induction of sex differentiation based on the observed difference of sex specific gene expression among sexes and germ cell development with two types of scallop GnRHs were demonstrated. And the occurrence of steroidogenic pathway-related genes, which is suggested mediating the abovementioned GnRH function, was proposed and sex specific profile of these genes between sexes during reproductive cycle was suggested.
Primary structure of oocyte maturation arresting factor (OMAF), which is a neural factor to interfere serotonin-induced spawning was revealed. And neutralizing full OMAF antibody resulted in blockage of OMAF-inhibited serotonin function and activation of spawning of male and sperm motility.
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