| Budget Amount *help |
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2018: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2017: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2016: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
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| Outline of Final Research Achievements |
Nitric oxide (NO) is an essential signal mediator, but it is unstable and not easy to handle. Caged compound is one of the useful compound category, and we have been developed caged NOs and the caged compounds of the species related to NO. In this project, we have developed novel caged NOs. One of them is a caged NO responding to yellowish-green light irradiation, which was found to be applicable to ex vivo experiments. The second is a nanoparticle version of caged NO. The third one is a version of caged NO responding to red light which was also applicable to ex vivo experiments.
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