Precision Medicine in Cardiology: Personalizing the Management in the Patients with Coronary Artery Disease

• Project/Area Number: 16H05215
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Medical sociology
• Research Institution: Keio University
• Principal Investigator: KOHSAKA Shun 慶應義塾大学, 医学部(信濃町), 講師 (30528659)
• Co-Investigator(Kenkyū-buntansha): 宮田 裕章 東京大学, 医学部附属病院, 特任教授 (70409704)
• Project Period (FY): 2016-04-01 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000); Fiscal Year 2019: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000); Fiscal Year 2018: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2017: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000); Fiscal Year 2016: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
• Keywords: 医療の質 / 冠動脈疾患 / 冠動脈インターベンション / アウトカム / 経皮的冠動脈インターベンション / 個別化医療 / 心不全・心房細動 / レジストリ・データベース / 心不全 / 心房細動 / レジストリ / 経皮的インターベンション / 循環器・高血圧 / 医療・福祉 / 社会医学 / 情報工学

Outline of Final Research Achievements

The purpose of the project was to utilize the large-scale procedure-based registry dataset to establish infrastructure for providing 'precision medicine' in the management of patients with coronary artery disease. We aimed to benchmark the performance of PCI (percutaneous coronary intervention; non-surgical procedure that uses a catheter to place a small structure called a stent to open up blood vessels in the heart that have been narrowed by atherosclerosis) for participating institutions, and build risk-models related to adverse outcome during and after the procedure.

We have reported the baseline characteristics and clinical outcomes of patients who underwent PCI in the region (registered roughly 27.000 patients) and compared the information with the registries and database obtained in other countries. In additon, validation of the key in-hospital outcomes were performed, and aim to include the long-term follow-up information within our risk models in the near future.

Academic Significance and Societal Importance of the Research Achievements

その主要な成果に関しては主要な学会発表ならびに学術誌に公表されており、このうち数編は国内の診療ガイドラインにも引用されている（JCS 2020
Guideline Focused Update on Antithrombotic Therapy in Patients With Coronary Artery Disease; JCS 2018 Guideline on Diagnosis and Treatment of
Acute Coronary Syndrome）。今後はさらに国際協力施設との連携を深め、我が国で規定される診療ガイドライン推奨の遵守率の算出や推移の評価を行う予定である。

Research Products

• [Journal Article] Presentation Pattern of Lower Extremity Endovascular Intervention versus Percutaneous Coronary Intervention (2020)
  • Author(s): Takahara Mitsuyoshi、Iida Osamu、Kohsaka Shun、Soga Yoshimitsu、Fujihara Masahiko、Shinke Toshiro、Amano Tetsuya、Ikari Yuji、on behalf of the J-EVT and J-PCI investigators
  • Journal Title: Journal of Atherosclerosis and Thrombosis Volume: 27 Issue: 8 Pages: 761-768
  • DOI: 10.5551/jat.53330
  • NAID: 130007883653
  • ISSN: 1340-3478, 1880-3873
  • Year and Date: 2020-08-01
  • Peer Reviewed / Open Access
• [Journal Article] JCS 2020 Guideline Focused Update on Antithrombotic Therapy in Patients With Coronary Artery Disease (2020)
  • Author(s): Nakamura Masato、Kimura Kazuo、Kimura Takeshi、Ishihara Masaharu、Otsuka Fumiyuki、Kozuma Ken、Kosuge Masami、Shinke Toshiro、Nakagawa Yoshihisa、Natsuaki Masahiro、Yasuda Satoshi、Akasaka Takashi、Kohsaka Shun、Haze Kazuo、Hirayama Atsushi
  • Journal Title: Circulation Journal Volume: 84 Issue: 5 Pages: 831-865
  • DOI: 10.1253/circj.CJ-19-1109
  • NAID: 130007835141
  • ISSN: 1346-9843, 1347-4820
  • Year and Date: 2020-04-24
  • Peer Reviewed / Open Access
• [Journal Article] Ischemic and Bleeding Events Among Patients With Acute Coronary Syndrome Associated With Low-Dose Prasugrel vs Standard-Dose Clopidogrel Treatment (2020)
  • Author(s): Shoji Satoshi、Sawano Mitsuaki、Sandhu Alexander T.、Heidenreich Paul A.、Shiraishi Yasuyuki、Ikemura Nobuhiro、Ueno Koji、Suzuki Masahiro、Numasawa Yohei、Fukuda Keiichi、Kohsaka Shun
  • Journal Title: JAMA Network Open Volume: 3 Issue: 4 Pages: e202004-e202004
  • DOI: 10.1001/jamanetworkopen.2020.2004
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Transradial percutaneous coronary intervention in patients with advanced chronic kidney disease (2020)
  • Author(s): Yashima Fumiaki、Inohara Taku、Numasawa Yohei、Kuno Toshiki、Sawano Mitsuaki、Ueno Koji、Shimoji Kenichiro、Noma Shigetaka、Fukuda Keiichi、Kohsaka Shun
  • Journal Title: Cardiovascular Revascularization Medicine Volume: Epub ahead of print Issue: 9 Pages: 1138-1143
  • DOI: 10.1016/j.carrev.2020.02.004
  • Peer Reviewed
• [Journal Article] Incidence and In-Hospital Outcomes of Patients Presenting With Stent Thrombosis (from the Japanese Nationwide Percutaneous Coronary Intervention Registry) (2020)
  • Author(s): Ohno Yohei、Yamaji Kyohei、Kohsaka Shun、Inohara Taku、Amano Tetsuya、Ishii Hideki、Kadota Kazushige、Nakamura Masato、Nakazawa Gaku、Yoshimachi Fuminobu、Ikari Yuji
  • Journal Title: The American Journal of Cardiology Volume: 125 Issue: 5 Pages: 720-726
  • DOI: 10.1016/j.amjcard.2019.12.005
  • Peer Reviewed
• [Journal Article] Primary Percutaneous Coronary Intervention in Elderly Patients With Acute Myocardial Infarction ― An Analysis From a Japanese Nationwide Claim-Based Database ― (2019)
  • Author(s): Uemura Shiro、Okamoto Hiroshi、Nakai Michikazu、Nishimura Kunihiro、Miyamoto Yoshihiro、Yasuda Satoshi、Tanaka Nobuhiro、Kohsaka Shun、Kadota Kazushige、Saito Yoshihiko、Tsutsui Hiroyuki、Komuro Issei、Ikari Yuji、Ogawa Hisao、Nakamura Masato
  • Journal Title: Circulation Journal Volume: 83 Issue: 6 Pages: 1229-1238
  • DOI: 10.1253/circj.CJ-19-0004
  • NAID: 130007652783
  • ISSN: 1346-9843, 1347-4820
  • Year and Date: 2019-05-24
  • Peer Reviewed / Open Access
• [Journal Article] JCS 2018 Guideline on Diagnosis and Treatment of Acute Coronary Syndrome (2019)
  • Author(s): Kimura Kazuo、Kimura Takeshi、Ishihara Masaharu、Tanaka Akihito、Tamura Toshihiro、Nakashima Takahiro、Noguchi Teruo、Fukamachi Daisuke、Mizuno Tomohiro、Yamaguchi Junichi、Yodogawa Kenji、Kosuge Masami、Kohsaka Shun et al.
  • Journal Title: Circulation Journal Volume: 83 Issue: 5 Pages: 1085-1196
  • DOI: 10.1253/circj.CJ-19-0133
  • NAID: 130007636985
  • ISSN: 1346-9843, 1347-4820
  • Year and Date: 2019-04-25
  • Peer Reviewed / Open Access
• [Journal Article] In-hospital outcome in patients presenting with acute coronary syndrome with left main coronary artery disease: A report from Japanese prospective multicenter percutaneous coronary intervention registry (2019)
  • Author(s): Tani Hidenori、Sawano Mitsuaki、Numasawa Yohei、Kobayashi Yuhei、Suzuki Masahiro、Noma Shigetaka、Shiraishi Yasuyuki、Ueda Ikuko、Fukuda Keiichi、Kohsaka Shun
  • Journal Title: Journal of Cardiology Volume: Epub ahead of print Issue: 6 Pages: 635-640
  • DOI: 10.1016/j.jjcc.2019.11.006
  • Peer Reviewed
• [Journal Article] Diabetes mellitus and other cardiovascular risk factors in lower-extremity peripheral artery disease versus coronary artery disease: an analysis of 1,121,359 cases from the nationwide databases (2019)
  • Author(s): Takahara Mitsuyoshi、the J-EVT and J-PCI investigators、Iida Osamu、Kohsaka Shun、Soga Yoshimitsu、Fujihara Masahiko、Shinke Toshiro、Amano Tetsuya、Ikari Yuji
  • Journal Title: Cardiovascular Diabetology Volume: 18 Issue: 1 Pages: 155-155
  • DOI: 10.1186/s12933-019-0955-5
  • Peer Reviewed / Open Access
• [Journal Article] Outcomes of acute coronary syndrome patients with concurrent extra-cardiac vascular disease in the era of transradial coronary intervention: A retrospective multicenter cohort study (2019)
  • Author(s): Kodaira Masaki、Sawano Mitsuaki、Kuno Toshiki、Numasawa Yohei、Noma Shigetaka、Suzuki Masahiro、Imaeda Shohei、Ueda Ikuko、Fukuda Keiichi、Kohsaka Shun
  • Journal Title: PLOS ONE Volume: 14 Issue: 10 Pages: e0223215-e0223215
  • DOI: 10.1371/journal.pone.0223215
  • Peer Reviewed / Open Access
• [Journal Article] Impact of reduced-dose prasugrel vs. standard-dose clopidogrel on in-hospital outcomes of percutaneous coronary intervention in 62?737 patients with acute coronary syndromes: a nationwide registry study in Japan (2019)
  • Author(s): Akita Keitaro、Inohara Taku、Yamaji Kyohei、Kohsaka Shun、Numasawa Yohei、Ishii Hideki、Amano Tetsuya、Kadota Kazushige、Nakamura Masato、Maekawa Yuichiro
  • Journal Title: European Heart Journal - Cardiovascular Pharmacotherapy Volume: pii Issue: 4 Pages: 231-238
  • DOI: 10.1093/ehjcvp/pvz056
  • Peer Reviewed / Open Access
• [Journal Article] Association Between Current and Future Annual Hospital Percutaneous Coronary Intervention Mortality Rates (2019)
  • Author(s): Sandhu Alexander T.、Kohsaka Shun、Bhattacharya Jay、Fearon William F.、Harrington Robert A.、Heidenreich Paul A.
  • Journal Title: JAMA Cardiology Volume: 4 Issue: 11 Pages: 1077-1077
  • DOI: 10.1001/jamacardio.2019.3221
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Risk stratification model for in-hospital death in patients undergoing percutaneous coronary intervention: a nationwide retrospective cohort study in Japan (2019)
  • Author(s): Inohara Taku、Kohsaka Shun、Yamaji Kyohei、Ishii Hideki、Amano Tetsuya、Uemura Shiro、Kadota Kazushige、Kumamaru Hiraku、Miyata Hiroaki、Nakamura Masato
  • Journal Title: BMJ Open Volume: 9 Issue: 5 Pages: e026683-e026683
  • DOI: 10.1136/bmjopen-2018-026683
  • Peer Reviewed / Open Access
• [Journal Article] In-Hospital Outcomes After Percutaneous Coronary Intervention for Acute Coronary Syndrome With Cardiogenic Shock (from a Japanese Nationwide Registry [J-PCI Registry]) (2019)
  • Author(s): Kubo Shunsuke、Yamaji Kyohei、Inohara Taku、Kohsaka Shun、Tanaka Hiroyuki、Ishii Hideki、Uemura Shiro、Amano Tetsuya、Nakamura Masato、Kadota Kazushige
  • Journal Title: The American Journal of Cardiology Volume: 123 Issue: 10 Pages: 1595-1601
  • DOI: 10.1016/j.amjcard.2019.02.015
  • Peer Reviewed
• [Journal Article] Comparison of Outcomes After Percutaneous Coronary Intervention in Elderly Patients, Including 10?628 Nonagenarians: Insights From a Japanese Nationwide Registry (J‐PCI Registry) (2019)
  • Author(s): Numasawa Yohei、Inohara Taku、Ishii Hideki、Yamaji Kyohei、Kohsaka Shun、Sawano Mitsuaki、Kodaira Masaki、Uemura Shiro、Kadota Kazushige、Amano Tetsuya、Nakamura Masato et al.
  • Journal Title: Journal of the American Heart Association Volume: 8 Issue: 5
  • DOI: 10.1161/jaha.118.011017
  • Peer Reviewed / Open Access
• [Journal Article] Stroke After Percutaneous Coronary Intervention in the Era of Transradial Intervention. (2018)
  • Author(s): Shoji S, Kohsaka S, Kumamaru H, Sawano M, Shiraishi Y, Ueda I, Noma S, Suzuki M, Numasawa Y, Hayashida K, Yuasa S, Miyata H, Fukuda K.
  • Journal Title: Circ Cardiovasc Interv. Volume: 11(12) Issue: 12
  • DOI: 10.1161/circinterventions.118.006761
  • Peer Reviewed
• [Journal Article] Association of Renin-Angiotensin Inhibitor Treatment With Mortality and Heart Failure Readmission in Patients With Transcatheter Aortic Valve Replacement (2018)
  • Author(s): Inohara Taku、Manandhar Pratik、Kosinski Andrzej S.、Matsouaka Roland A.、Kohsaka Shun、Mentz Robert J.、Thourani Vinod H.、Carroll John D.、Kirtane Ajay J.、Bavaria Joseph E.、Cohen David J.、Kiefer Todd L.、Gaca Jeffrey G.、Kapadia Samir R.、Peterson Eric D.、Vemulapalli Sreekanth
  • Journal Title: JAMA Volume: 320 Issue: 21 Pages: 2231-2231
  • DOI: 10.1001/jama.2018.18077
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] An overview of percutaneous coronary intervention in dialysis patients: Insights from a Japanese nationwide registry (2018)
  • Author(s): Numasawa Yohei、Inohara Taku、Ishii Hideki、Yamaji Kyohei、Hirano Keita、Kohsaka Shun、Sawano Mitsuaki、Kuno Toshiki、Kodaira Masaki、Uemura Shiro、Kadota Kazushige、Amano Tetsuya、Nakamura Masato、on behalf of the J-PCI Registry Investigators
  • Journal Title: Catheterization and Cardiovascular Interventions Volume: 94 Issue: 1
  • DOI: 10.1002/ccd.27986
  • Peer Reviewed
• [Journal Article] Impact of catheter-induced iatrogenic coronary artery dissection with or without postprocedural flow impairment: A report from a Japanese multicenter percutaneous coronary intervention registry. (2018)
  • Author(s): Hiraide T, Sawano M, Shiraishi Y, Ueda I, Numasawa Y, Noma S, Negishi K, Ohki T, Yuasa S, Hayashida K, Miyata H, Fukuda K, Kohsaka S.
  • Journal Title: PLoS One. Volume: 13(9) Issue: 9 Pages: e0204333-e0204333
  • DOI: 10.1371/journal.pone.0204333
  • Peer Reviewed / Open Access
• [Journal Article] Consequence of reimbursement policy alteration for urgent PCI in Japan (2018)
  • Author(s): Ikemura Nobuhiro、Sawano Mitsuaki、Ueda Ikuko、Fukuda Keiichi、Kohsaka Shun
  • Journal Title: The Lancet Volume: 391 Issue: 10136 Pages: 2208-2209
  • DOI: 10.1016/s0140-6736(18)30857-2
  • Open Access
• [Journal Article] Lower Cardiovascular Risk Associated with SGLT-2i in >400,000 Patients: The CVD-REAL 2 Study. (2018)
  • Author(s): Kosiborod M, Lam CSP, Kohsaka S, Kim DJ, Karasik A, Shaw J, Tangri N, Goh SY, Thuresson M, Chen H, Surmont F, Hammar N, Fenici P; CVD-REAL Investigators and Study Group.
  • Journal Title: J Am Coll Cardiol. Volume: pii: S0735-1097(18) Issue: 23 Pages: 33528-9
  • DOI: 10.1016/j.jacc.2018.03.009
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Association between institutional procedural preference and in-hospital outcomes in laparoscopic surgeries; Insights from a retrospective cohort analysis of a nationwide surgical database in Japan. (2018)
  • Author(s): Miyata H, Mori M, Kokudo N, Gotoh M, Konno H, Wakabayashi G, Matsubara H, Watanabe T, Ono M, Hashimoto H, Yamamoto H, Kumamaru H, Kohsaka S, Iwanaka T.
  • Journal Title: PLoS One. Volume: 13(3) Issue: 3 Pages: e0193186-e0193186
  • DOI: 10.1371/journal.pone.0193186
  • Peer Reviewed / Open Access
• [Journal Article] Predictors of high cost after percutaneous coronary intervention: A review from Japanese multicenter registry overviewing the influence of procedural complications. (2017)
  • Author(s): Inohara T, Numasawa Y, Higashi T, Ueda I, Suzuki M, Hayashida K, Yuasa S, Maekawa Y, Fukuda K, Kohsaka S.
  • Journal Title: Am Heart J. Volume: 194 Pages: 61-72
  • DOI: 10.1016/j.ahj.2017.08.008
  • Peer Reviewed
• [Journal Article] Prognostic Impact of Subsequent Acute Coronary Syndrome and Unplanned Revascularization on Long-Term Mortality After an Index Percutaneous Coronary Intervention: A Report From a Japanese Multicenter Registry. (2017)
  • Author(s): Inohara T, Kohsaka S, Miyata H, Sawano M, Ueda I, Maekawa Y, Fukuda K, Jones PG, Cohen DJ, Zhao Z, Spertus JA, Smolderen KG.
  • Journal Title: J Am Heart Assoc. Volume: 6(11) Issue: 11
  • DOI: 10.1161/jaha.117.006529
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Bleeding risk of apixaban, dabigatran, and low-dose rivaroxaban compared with warfarin in Japanese patients with non-valvular atrial fibrillation: a propensity matched analysis of administrative claims data. (2017)
  • Author(s): Kohsaka S, Murata T, Izumi N, Katada J, Wang F, Terayama Y.
  • Journal Title: Curr Med Res Opin. Volume: 33(11) Issue: 11 Pages: 1955-1963
  • DOI: 10.1080/03007995.2017.1374935
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Inconsistent Dosing of Non-Vitamin K Oral Anticoagulants: Differences Between the United States and Japan. (2017)
  • Author(s): Ono T, Kohsaka S, Takatsuki S, Fukuda K, Suzuki M.
  • Journal Title: J Am Coll Cardiol. Volume: 70(1) Issue: 1 Pages: 118-118
  • DOI: 10.1016/j.jacc.2017.03.609
  • Peer Reviewed
• [Journal Article] Effect of Compliance to Updated AHA/ACC Performance and Quality Measures Among Patients With Atrial Fibrillation on Outcome (from Japanese Multicenter Registry) (2017)
  • Author(s): Inohara Taku、Kimura Takehiro、Ueda Ikuko、Ikemura Nobuhiro、Tanimoto Kojiro、Nishiyama Nobuhiro、Aizawa Yoshiyasu、Nishiyama Takahiko、Katsumata Yoshinori、Fukuda Keiichi、Takatsuki Seiji、Kohsaka Shun
  • Journal Title: The American Journal of Cardiology Volume: 120 Issue: 4 Pages: 595-600
  • DOI: 10.1016/j.amjcard.2017.05.029
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Impact of Institutional and Operator Volume on Short-Term Outcomes of Percutaneous Coronary Intervention: A Report From the Japanese Nationwide Registry. (2017)
  • Author(s): Inohara T, Kohsaka S, Yamaji K, Amano T, Fujii K, Oda H, Uemura S, Kadota K, Miyata H, Nakamura M; J-PCI Registry Investigators.
  • Journal Title: JACC Cardiovasc Interv. Volume: 10(9) Issue: 9 Pages: 918-927
  • DOI: 10.1016/j.jcin.2017.02.015
  • Peer Reviewed
• [Journal Article] Relation of ST-Segment Elevation Myocardial Infarction to Daily Ambient Temperature and Air Pollutant Levels in a Japanese Nationwide Percutaneous Coronary Intervention Registry. (2017)
  • Author(s): Yamaji K, Kohsaka S, Morimoto T, Fujii K, Amano T, Uemura S, Akasaka T, Kadota K, Nakamura M, Kimura T; J-PCI Registry Investigators.
  • Journal Title: Am J Cardiol. Volume: 15 Issue: 6 Pages: 872-880
  • DOI: 10.1016/j.amjcard.2016.11.041
  • Peer Reviewed
• [Journal Article] Barriers Associated With Door-to-Balloon Delay in Contemporary Japanese Practice (2017)
  • Author(s): Ikemura N, Sawano M, Shiraishi Y, Ueda I, Miyata H, Numasawa Y, Noma S, Suzuki M, Momiyama Y, Inohara T, Hayashida K, Yuasa S, Maekawa Y, Fukuda K, Kohsaka S.
  • Journal Title: Circulation Journal Volume: 81 Issue: 6 Pages: 815-822
  • DOI: 10.1253/circj.CJ-16-0905
  • NAID: 130005679702
  • ISSN: 1346-9843, 1347-4820
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Impact of the Clinical Frailty Scale on Outcomes After Transcatheter Aortic Valve Replacement. (2017)
  • Author(s): Shimura T, Yamamoto M, Kano S, Kagase A, Kodama A, Koyama Y, Tsuchikane E, Suzuki T, Otsuka T, Kohsaka S, Tada N, Yamanaka F, Naganuma T, Araki M, Shirai S, Watanabe Y, Hayashida K
  • Journal Title: Circulation Volume: Epub ahead of print Issue: 21 Pages: 2013-2024
  • DOI: 10.1161/circulationaha.116.025630
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Incidence and predictors of bleeding complications after percutaneous coronary intervention. (2017)
  • Author(s): Numasawa Y, Kohsaka S, Ueda I, Miyata H, Sawano M, Kawamura A, Noma S, Suzuki M, Nakagawa S, Momiyama Y, Fukuda K.
  • Journal Title: J Cardiol. Volume: 69(1) Issue: 1 Pages: 272-279
  • DOI: 10.1016/j.jjcc.2016.05.003
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Use of renin-angiotensin system inhibitors after coronary interventions in patients with the guideline-based indications: A report from a Japanese multicenter registry. (2016)
  • Author(s): Ikemura N, Sawano M, Miyata H, Ueda I, Numasawa Y, Noma S, Suzuki M, Momiyama Y, Maekawa Y, Fukuda K, Kohsaka S.
  • Journal Title: Int J Cardiol. Volume: 225 Pages: 362-364
  • DOI: 10.1016/j.ijcard.2016.09.083
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Effect of Pre-Procedural Beta-Blocker in Patients Undergoing Percutaneous Coronary Intervention. (2016)
  • Author(s): Maekawa Y, Miyata H, Ueda I, Ikemura N, Fukuda K, Kohsaka S.
  • Journal Title: JACC Cardiovasc Interv. Volume: 9(23) Issue: 23 Pages: 2458-2459
  • DOI: 10.1016/j.jcin.2016.09.043
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Presentation] Heart Team Approach for CABG/PCI Reports from Data Registration Systems in Japan (2017)
  • Author(s): 香坂 俊
  • Organizer: 第81回日本循環器学会
  • Place of Presentation: ホテル金澤（石川県金沢市）
  • Int'l Joint Research / Invited
• [Presentation] 循環器データーベース研究 (2016)
  • Author(s): 香坂 俊
  • Organizer: 日本臨床疫学学会 発足記念講演会
  • Place of Presentation: 東京大学弥生講堂（東京都文京区）
  • Invited
• [Presentation] 臨床試験の結果に現実性を持たせるために (2016)
  • Author(s): 香坂 俊
  • Organizer: 第19回日本線子検出と治療学会総会
  • Place of Presentation: 神戸国際会議場（兵庫県神戸市）
  • Invited
• [Presentation] 循環器領域における学会や医師主導のClinical Databaseとビッグデータの連携を考える (2016)
  • Author(s): 香坂 俊
  • Organizer: 第64回心臓病学会学術集会
  • Place of Presentation: 東京国際フォーラム（東京都千代田区）
  • Invited
• [Presentation] 日本におけるPCIの標準的適応：日本の標準化指標作成に何が必要か (2016)
  • Author(s): 香坂 俊
  • Organizer: 第25回日本心血管インターベンション治療学会学術集会
  • Place of Presentation: 東京国際フォーラム（東京都千代田区）
  • Invited