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Verification of the process by which improvement of oral function maintains and improves cognitive and motor function of elderly people through nutrition improvement

Research Project

Project/Area Number 16H05523
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Prosthodontics/ Dental materials science and
Research InstitutionOsaka University

Principal Investigator

Maeda Yoshinobu  大阪大学, 歯学研究科, 特任教授 (10144510)

Co-Investigator(Kenkyū-buntansha) 池邉 一典  大阪大学, 歯学研究科, 教授 (70273696)
権田 知也  大阪大学, 歯学部附属病院, 講師 (30324792)
権藤 恭之  大阪大学, 人間科学研究科, 教授 (40250196)
神出 計  大阪大学, 医学系研究科, 教授 (80393239)
大久保 公美  国立保健医療科学院, 生涯健康研究部, 主任研究官 (80407577)
増井 幸恵  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (10415507)
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2018: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2016: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
Keywords歯学 / 咬合力 / 栄養 / 運動機能 / 認知機能 / 縦断研究 / 健康長寿
Outline of Final Research Achievements

In the model that examined the relationship between nutritional status and oral function, it became clear that those with low occlusal force tended to lose nutritional status even after adjusting for other confounding factors. As a result of examining the relationship with the state in the oral status such as the number of teeth and occlusal force after inferring the amount of masticatory muscle activity in the daily diet of the elderly from the intake of various foods, it was found that those with low occlusal power avoided eating hard food and that their masticatory muscle activity decreased.In the model that examined the relationship between cognitive function and oral function, it was revealed that the those with low occlusal force was related to the decrease in cognitive function even after adjusting the factor related to cognitive function.

Academic Significance and Societal Importance of the Research Achievements

高齢期まで歯や口腔機能を維持することは,栄養状態の悪化を防ぎ,さらに,それらは認知機能低下を抑制することから,歯科治療による口腔機能を維持・回復は,食生活の改善,認知症予防,延いては,介護予防につながることが示唆された.このことから,口腔健康の向上を推進することで,社会費用削減につながる可能性が示された.この結果は,医療関係者のみならず,日本国民や世界の人々へと広く影響を及ぼすことができると考えられる.

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • Research Products

    (11 results)

All 2019 2018 2017

All Journal Article (8 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 8 results,  Open Access: 7 results,  Acknowledgement Compliant: 1 results) Presentation (3 results) (of which Int'l Joint Research: 3 results)

  • [Journal Article] Relationship between oral stereognostic ability and dietary intake in older Japanese adults with complete dentures2019

    • Author(s)
      Fukutake Motoyoshi、Ikebe Kazunori、Okubo Hitomi、Matsuda Ken-ichi、Enoki Kaori、Inomata Chisato、Takeshita Hajime、Mihara Yusuke、Hatta Kodai、Gondo Yasuyuki、Kamide Kei、Masui Yukie、Ishizaki Tatsuro、Arai Yasumichi、Maeda Yoshinobu
    • Journal Title

      Journal of Prosthodontic Research

      Volume: 63 Issue: 1 Pages: 105-109

    • DOI

      10.1016/j.jpor.2018.10.001

    • NAID

      130007604164

    • ISSN
      1883-1958, 1883-9207
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Lack of posterior occlusal support predicts the reduction in walking speed in 80‐year‐old Japanese adults: A 3‐year prospective cohort study with propensity score analysis by the SONIC Study Group2019

    • Author(s)
      Hatta Kodai、Ikebe Kazunori、Mihara Yusuke、Gondo Yasuyuki、Kamide Kei、Masui Yukie、Sugimoto Ken、Matsuda Ken‐ichi、Fukutake Motoyoshi、Kabayama Mai、Shintani Ayumi、Ishizaki Tatsuro、 Arai Yasumichi、Rakugi Hiromi、Maeda Yoshinobu
    • Journal Title

      Gerodontology

      Volume: - Issue: 2 Pages: 156-162

    • DOI

      10.1111/ger.12393

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Association of handgrip strength with various oral functions in 82- to 84-year-old communitydwelling Japanese2018

    • Author(s)
      Mihara Yusuke、Matsuda Ken-ichi、Ikebe Kazunori、Hatta Koudai、Fukutake Motoyoshi、Enoki Kaori、Ogawa Taiji、Takeshita Hajime、Inomata Chisato、Gondo Yasuyuki、Masui Yukie、Kamide Kei、Sugimoto Ken、Kabayama Mai、Ishizaki Tatsuro、Arai Yasumichi、Maeda Yoshinobu
    • Journal Title

      Gerodontology

      Volume: 35 Issue: 3 Pages: 214-220

    • DOI

      10.1111/ger.12341

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Relationship between gerotranscendence and oral health-related quality of life2018

    • Author(s)
      Mihara Yusuke、Matsuda Ken-ichi、Hatta Koudai、Gondo Yasuyuki、Masui Yukie、Nakagawa Takeshi、 Kamide Kei、Ishizaki Tatsuro、Arai Yasumichi、Maeda Yoshinobu、Ikebe Kazunori
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 45 Issue: 10 Pages: 805-809

    • DOI

      10.1111/joor.12691

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Influence of lack of posterior occlusal support on cognitive decline among 80-year-old Japanese pople in a 3-year prospective study2018

    • Author(s)
      Hatta K、Ikebe K、Gondo Y、Kamide K、Masui Y、Inagaki H、Nakagawa T、Matsuda K、Ogawa T、 Inomata C、Takeshita H、Mihara Y、Fukutake M、Kitamura M、Murakami S、Kabayama M、Ishizaki T、 Arai Y、Sugimoto K、Rakugi H、Maeda Y
    • Journal Title

      Geriatrics & Gerontology International

      Volume: 18 Issue: 10 Pages: 1439-1446

    • DOI

      10.1111/ggi.13508

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Relationship between Atherosclerosis and Occlusal Support of Natural Teeth with Mediating Effect of Atheroprotective Nutrients: from the SONIC Study.2017

    • Author(s)
      Tada, S., Ikebe, K., Kamide, K., et al.
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 8 Pages: e0182563-e0182563

    • DOI

      10.1371/journal.pone.0182563

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between dietary patterns and cognitive function among 70-year-old Japanese elderly: a cross-sectional analysis of the SONIC study2017

    • Author(s)
      Okubo H., Inagaki H., Gondo Y., Kamide K., Ikebe K., Masui Y., Arai Y., Ishizaki T., Sasaki S., Nakagawa T., Kabayama M., Sugimoto K., Rakugi H., Maeda Y; SONIC Study Group.
    • Journal Title

      Nutrition Journal

      Volume: 16 Issue: 1 Pages: 56-56

    • DOI

      10.1186/s12937-017-0273-2

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Dietary intake is associated with occlusal force rather than number of teeth in 80-year-old Japanese2017

    • Author(s)
      Inomata C, Ikebe K, Okubo H, Takeshita H, Mihara Y, Hatta K, Tada S, Enoki K, Ogawa T, Matsuda K, Gondo Y, Masui Y, Kamide K, Takahashi R, Arai Y, Maeda Y
    • Journal Title

      JDR Clinical & Translational Research

      Volume: 2 Pages: 187-197

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Occlusal contacts predict decline in cognitive decline in 3-years2018

    • Author(s)
      Hatta K, Matsuda K, Gondo Y, Kamide K, Masui Y, Ishizaki T, Arai Y, Sugimoto K, Mihara Y, Inomata C, Takeshita H, Enoki K, Fukutake M, Sato H, Maeda Y, Ikebe K
    • Organizer
      International Association for Dental Research
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Influence of occlusal force on malnutrition in older adults.2018

    • Author(s)
      Fukutake M, Hatta K, Sato H, Mihara Y, Inomata C, Takeshita H, Enoki K, Matsuda K, Gondo Y, Kamide K, Arai Y, Ishizaki T, Masui Y, Maeda Y, Ikebe K
    • Organizer
      International Association for Dental Research
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Influence of occlusal force on 3-years weight loss in elders2018

    • Author(s)
      Fukutake M, Ikebe K, Hatta K et al.
    • Organizer
      AADR Annual Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research

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Published: 2016-04-21   Modified: 2020-03-30  

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