| Budget Amount *help |
¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000)
Fiscal Year 2018: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2017: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Fiscal Year 2016: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
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| Outline of Final Research Achievements |
Metal allergy is considered to be delayed-type of allergy by T-cell dependent diseases, but its immune mechanism is not well understood.
In this study, we performed to clarify the characteristics of T cells involved in the onset of metal allergy using the our technology. We found that non-biased gene amplification plays a very important role in T cell receptor analysis. Thus, in T cell receptor analysis, it is necessary to use a non-biased gene amplification method, such as a single chain adapter ligation PCR by our technology.
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