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Development and evaluation of an evidence-based infusion management program using visualization devices.

Research Project

Project/Area Number 16H05561
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Fundamental nursing
Research InstitutionThe University of Tokyo

Principal Investigator

Murayama Ryoko  東京大学, 医学部附属病院, 特任准教授 (10279854)

Co-Investigator(Kenkyū-buntansha) 松井 優子  公立小松大学, 保健医療学部, 教授 (00613712)
真田 弘美  東京大学, 大学院医学系研究科(医学部), 教授 (50143920)
土井 麻里 (阿部麻里)  東京大学, 医学部附属病院, 特任助教 (50802386)
高橋 聡明  東京大学, 大学院医学系研究科(医学部), 特任助教 (50824653)
小見山 智恵子  東京大学, 医学部附属病院, 看護部長 (60581634)
大江 真琴  東京大学, 医学部附属病院, 特任講師 (60389939)
Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥15,210,000 (Direct Cost: ¥11,700,000、Indirect Cost: ¥3,510,000)
Fiscal Year 2019: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2018: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2017: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2016: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Keywords看護技術 / 輸液療法 / 輸液看護 / 末梢静脈カテーテル留置 / 看護学 / 臨床看護学 / 看護理工学
Outline of Final Research Achievements

We have taken up research to develop an infusion management program that incorporates evidence-based assessment technology for the prevention and early detection of catheter failures. A care bundle using ultrasonography (US) was developed to prevent catheter failure due to mechanical irritation from peripheral intravenous catheter (PIVC) contact to the vessel wall. Next, we created an algorithm that standardized the US-assisted PIVC placement technique and confirmed that venipuncture by nurses who used it had a low incidence of catheter failures. Also, observation of skin surface temperature around the catheter indwelling area with a liquid crystal thermo-film showed a significant association between subcutaneous edema at the indwelling area with a characteristic temperature distribution pattern. It was suggested that the assessment of subcutaneous tissue with a liquid crystal thermo-film may be useful for early detection of abnormalities including extravasation.

Academic Significance and Societal Importance of the Research Achievements

本研究では、末梢静脈に留置したカテーテルが腫脹や発赤、疼痛などの症状や徴候を伴い、治療が完遂する前に抜去を余儀なくされる「点滴トラブル」を予防、あるいは早期発見するために、点滴トラブルの原因・要因解明の研究を続け、カテーテル留置アルゴリズムを作成し、有効性を評価した。本研究内での開発したプログラムの評価により改善点を見出したことで、今後普及につながる修正プログラムを考案することができた。今後は臨床現場に速やかに成果を還元する、つまりアルゴリズムを含めた教育プログラムを普及することで、患者の我慢を不要とし、医療者のワークロードを低減、さらには医療経済的にもコスト削減に寄与できると考える。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • Research Products

    (38 results)

All 2020 2019 2018 2017 2016 Other

All Journal Article (15 results) (of which Peer Reviewed: 15 results,  Open Access: 11 results,  Acknowledgement Compliant: 3 results) Presentation (21 results) (of which Int'l Joint Research: 10 results) Remarks (2 results)

  • [Journal Article] Development of an algorithm using ultrasonography-assisted peripheral intravenous catheter placement for reducing catheter failure2020

    • Author(s)
      Kanno Chiho、Murayama Ryoko、Abe-Doi Mari、Takahashi Toshiaki、Shintani Yui、Nogami Junko、Komiyama Chieko、Sanada Hiromi
    • Journal Title

      Drug Discoveries & Therapeutics

      Volume: 14 Issue: 1 Pages: 27-34

    • DOI

      10.5582/ddt.2019.01094

    • ISSN
      1881-7831, 1881-784X
    • Year and Date
      2020-02-29
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Preventing peripheral intravenous catheter failure by reducing mechanical irritation2020

    • Author(s)
      Takahashi Toshiaki、Murayama Ryoko、Abe-Doi Mari、Miyahara-Kaneko Maki、Kanno Chiho、Nakamura Miwa、Mizuno Mariko、Komiyama Chieko、Sanada Hiromi
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 1550-1550

    • DOI

      10.1038/s41598-019-56873-2

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Incidence, risk factors, and assessment of induration by ultrasonography after chemotherapy administration through a peripheral intravenous catheter2020

    • Author(s)
      Abe‐Doi Mari、Murayama Ryoko、Komiyama Chieko、Sanada Hiromi
    • Journal Title

      Japan Journal of Nursing Science

      Volume: 9 Issue: 3

    • DOI

      10.1111/jjns.12329

    • NAID

      210000173257

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Characteristics of subcutaneous tissues at the site of insertion of peripheral infusion in patients undergoing paclitaxel and carboplatin chemotherapy2019

    • Author(s)
      Murayama Ryoko、Oya Maiko、Abe-Doi Mari、Oe Makoto、Komiyama Chieko、Sanada Hiromi
    • Journal Title

      Drug Discoveries & Therapeutics

      Volume: 13 Issue: 5 Pages: 288-293

    • DOI

      10.5582/ddt.2019.01064

    • NAID

      130007744544

    • ISSN
      1881-7831, 1881-784X
    • Year and Date
      2019-10-31
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Ultrasonographic assessment of an induration caused by extravasation of a nonvesicant anticancer drug2019

    • Author(s)
      Abe-Doi Mari、Murayama Ryoko、Yabunaka Koichi、Tanabe Hidenori、Komiyama Chieko、Sanada Hiromi
    • Journal Title

      Medicine

      Volume: 98 Issue: 14 Pages: e15043-e15043

    • DOI

      10.1097/md.0000000000015043

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Exploring the causes of peripheral intravenous catheter failure based on shape of catheters removed from various insertion sites2018

    • Author(s)
      Murayama Ryoko、Takahashi Toshiaki、Tanabe Hidenori、Yabunaka Koichi、Oe Makoto、Komiyama Chieko、Sanada Hiromi
    • Journal Title

      Drug Discoveries & Therapeutics

      Volume: 12 Issue: 3 Pages: 170-177

    • DOI

      10.5582/ddt.2018.01024

    • NAID

      130007403867

    • ISSN
      1881-7831, 1881-784X
    • Year and Date
      2018-06-30
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Observational study at the time of peripheral venous catheter placement using the ultrasonography and qualitative sketching method2018

    • Author(s)
      高橋聡明, 村山陵子, 田邊秀憲, 玉井奈緒, 藪中幸一, 真田弘美.
    • Journal Title

      Journal of Nursing Science and Engineering

      Volume: 5 Issue: 1 Pages: 2-11

    • DOI

      10.24462/jnse.5.1_2

    • NAID

      130006330060

    • ISSN
      2188-4323, 2432-6283
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Continuous thermographic observation may predict extravasation in chemotherapy-treated2017

    • Author(s)
      Oya M, Murayama R, Oe M, Yabunaka K, Tanabe H, Takahashi T, Matsui Y, Otomo E, Komiyama C, Sanada H
    • Journal Title

      European Journal of Oncology Nursing

      Volume: 28 Pages: 56-61

    • DOI

      10.1016/j.ejon.2017.02.009

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Is thrombus with subcutaneous edema detected by ultrasonography related to short peripheral catheter failure?2017

    • Author(s)
      Takahashi T, Murayama R, Oe M, Nakagami G, Tanabe H, Yabunaka K, Arai R, Komiyama C, Uchida M, Sanada H.
    • Journal Title

      Journal of Infusion Nursing

      Volume: 40 Issue: 5 Pages: 313-322

    • DOI

      10.1097/nan.0000000000000216

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Removal of peripheral intravenous catheters due to catheter failures among adult patients.2017

    • Author(s)
      Murayama R, Uchida M, Oe M, Takahashi T, Oya M, Komiyama C, Sanada H.
    • Journal Title

      Journal of Infusion Nursing

      Volume: 40 Issue: 4 Pages: 224-231

    • DOI

      10.1097/nan.0000000000000168

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 看護師の末梢静脈路確保における留置針刺入・輸液ルート接続時の主観的体験.2017

    • Author(s)
      井上文, 保坂嘉成, 村山陵子, 田邊秀憲, 大江真琴, 内田美保, 小見山智恵子, 真田弘美.
    • Journal Title

      看護理工学会誌

      Volume: 4(1) Pages: 67-72

    • NAID

      130006406564

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 看護師の視点からとらえた輸液療法が患者の療養生活行動を妨げるプロセス.2017

    • Author(s)
      小林康司, 池田真理, 村山陵子, 大江真琴, 相馬光代, 鳩宿あゆみ, 小見山智恵子, 真田弘美.
    • Journal Title

      看護理工学会誌

      Volume: 4 (1) Pages: 39-48

    • NAID

      130006406577

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Low-angled peripheral intravenous catheter tip placement decreases phlebitis.2016

    • Author(s)
      Tanabe H, Murayama R, Yabunaka K, Oe M, Takahashi T, Komiyama C, Sanada H.
    • Journal Title

      The Journal of Vascular Access.

      Volume: 17(6) Issue: 6 Pages: 542-547

    • DOI

      10.5301/jva.5000601

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Ultrasonographic classification of subcutaneous edema caused by infusion via peripheral intravenous catheter.2016

    • Author(s)
      Yabunaka K, Murayama R, Tanabe H, Takahashi T, Oe M, Oya M, Fujioka M, Sanada H.
    • Journal Title

      Journal of medical ultrasound

      Volume: 24(2) Issue: 2 Pages: 60-65

    • DOI

      10.1016/j.jmu.2016.02.001

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Low-temperature infiltration identified using infrared thermography in patients with subcutaneous edema revealed ultrasonographically: A case report2016

    • Author(s)
      Oya M, Takahashi T, Tanabe H, Oe M, Murayama R, Yabunaka K, Matsui Y, Sanada H.
    • Journal Title

      Drug Discoveries & Therapeutics

      Volume: 10 Issue: 2 Pages: 117-122

    • DOI

      10.5582/ddt.2016.01033

    • NAID

      130005152841

    • ISSN
      1881-7831, 1881-784X
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Development of an algorithm using ultrasonography-assisted peripheral intravenous catheter placement for reducing catheter failure: uncontrolled Before and after study2019

    • Author(s)
      Ryoko Murayama, Chiho Kanno, Mari Abe, Toshiaki Takahashi, Yui Shintani, Junko Nogami, Chieko Komiyama, Hiromi Sanada
    • Organizer
      AVAS Scientific Meeting 2019
    • Related Report
      2019 Annual Research Report
  • [Presentation] Survey of induration development following anticancer drug administration through a peripheral intravenous catheter and risk factors by ultrasonography2019

    • Author(s)
      Mari Abe, Ryoko Murayama, Koichi Yabunaka, Mie Tsuge, Chieko Komiyama, Hiromi Sanada
    • Organizer
      AVAS Scientific Meeting 2019
    • Related Report
      2019 Annual Research Report
  • [Presentation] Catheter tip are possible resource for biological study on catheter failure2019

    • Author(s)
      Toshiaki Takahashi, Takeo Minematsu, Ryoko Murayama, Taketoshi Mori, Hiromi Sanada
    • Organizer
      AVAS Scientific Meeting 2019
    • Related Report
      2019 Annual Research Report
  • [Presentation] 抗がん剤投与前から硬結発生までの超音波診断装置を用いた皮下組織の観察:ケースレポート2019

    • Author(s)
      阿部麻里, 村山陵子, 真田弘美
    • Organizer
      第7回看護理工学会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] The influence of a peripheral intravenous catheterization on the sleep quality of patients.2018

    • Author(s)
      Murayama R, Abe M, Takahashi T, Kanno C, Sanada H.
    • Organizer
      5th World Congress on Vascular Access,
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of a needle for peripheral intravenous catheters to improve vein puncture using in vitro models.2018

    • Author(s)
      Tanabe H, Kawasaki M, Ueda T, Zushi Y, Murayama R, Abe M, Sanada H.
    • Organizer
      5th World Congress on Vascular Access,
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Interventional study of care protocols including using ultrasonography to reduce mechanical irritation for the prevention of peripheral intravenous catheter failure.2018

    • Author(s)
      Takahashi T, Murayama R, Abe M, Miyahara M, Kanno C, Sanada H.
    • Organizer
      5th World Congress on Vascular Access,
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 皮膚表面温度分布に着目した末梢静脈カテーテル留置部位の観察.2018

    • Author(s)
      村山 陵子, 阿部 麻里, 真田 弘美.
    • Organizer
      第44回日本看護研究学会学術集会,
    • Related Report
      2018 Annual Research Report
  • [Presentation] 抗がん剤の血管外漏出観察のための感温フィルムユーザビリティ調査.2018

    • Author(s)
      上山 恵三子, 阿部 麻里, 村山 陵子, 真田 弘美.
    • Organizer
      第22回日本看護管理学会学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 点滴スタンド装着型超音波プローブ支持機による末梢静脈カテーテル穿刺支援.2018

    • Author(s)
      高橋聡明, 村山陵子, 野口博史, 阿部麻里, 菅野 智穂, 森 武俊, 真田弘美.
    • Organizer
      第6 回看護理工学会学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 顕著な腫脹がみられない抗がん剤の血管外漏出の現象の基礎的検証.2017

    • Author(s)
      松井優子, 紺家千津子, 村山陵子, 田邊秀憲, 大江真琴, 元雄良治, 我妻孝則, 道渕路子, 木下幸子, 坂井恵子, 須釜淳子, 真田弘美.
    • Organizer
      第31回日本がん看護学会学術集会
    • Place of Presentation
      高知県高知市
    • Year and Date
      2017-02-04
    • Related Report
      2016 Annual Research Report
  • [Presentation] Efficacy of a poly-2-methoxyethlacrylate coating for intravascular catheters in a rabbit model.2017

    • Author(s)
      Tanabe H, Takemura N, Tominaga T, Murayama R, Oe M, Sanada H.
    • Organizer
      31st Annual Scientific Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A rabbit venous model of infusion infiltration to study the effect of a hyperosmotic solution.2017

    • Author(s)
      Tanabe H, Takemura N, Murayama R, Oe M, Sanada H.
    • Organizer
      The Australian Vascular Access Society 2nd Scientific Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Usefulness of tablet-type ultranonography for assessing peripharal veins for intravenous catheterization: a pilot study.2017

    • Author(s)
      Takahashi T, Murayama R, Yabunaka K, Tanabe H, Sanada H.
    • Organizer
      The Australian Vascular Access Society 2nd Scientific Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Exproring the cause of the peripheral intravenous catheter failure with an upper arm catheterization: case report.2017

    • Author(s)
      Murayama R, Takahashi T, Tanabe H, Yabunaka K, Oe M, Sanada H.
    • Organizer
      The Australian Vascular Access Society 2nd Scientific Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] パクリタキセル・カルボプラチン療法における末梢点滴刺入部の皮下組織の特徴.2017

    • Author(s)
      大屋麻衣子, 村山陵子, 大江真琴, 田邊秀憲, 藪中幸一, 小見山智恵子, 真田弘美.
    • Organizer
      第26回日本創傷・オストミー・失禁管理学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 超音波検査とスケッチ技法を用いた末梢静脈カテーテル留置時の観察研究2016

    • Author(s)
      高橋聡明, 村山陵子, 田邊秀憲, 玉井奈緒, 藪中幸一, 真田弘美.
    • Organizer
      第4回看護理工学会学術集会
    • Place of Presentation
      岩手県滝沢市
    • Year and Date
      2016-10-09
    • Related Report
      2016 Annual Research Report
  • [Presentation] Low-angled catheter tip placement decreased phlebitis.2016

    • Author(s)
      Tanabe H, Murayama R, Yabunaka K, Oe M, Takahashi T, Komiyama C, Sanada H.
    • Organizer
      4th World Congress on Vascular Access
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2016-06-24
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Thrombus with subcutaneous edema detected by ultrasonography related to peripheral intravenous catheter failure.2016

    • Author(s)
      Takahashi T, Murayama R, Oe M, Nakagami G, Tanabe H, Yabunaka K, Arai R, Komiyama C, Uchida M, Sanada H.
    • Organizer
      4th World Congress on Vascular Access
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2016-06-24
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The influence of a peripheral intravenous catheter on the vein and subcutaneous tissue.2016

    • Author(s)
      Murayama R, Tanabe H, Yabunaka K, Oe M, Komiyama C, Sanada H.
    • Organizer
      4th World Congress on Vascular Access
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2016-06-23
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] サーモグラフィを用いた温度分布による抗癌剤血管外漏出アセスメント方法の開発.2016

    • Author(s)
      大屋麻衣子, 村山陵子, 大江真琴,田邊秀憲, 藪中幸一, 松井優子, 小見山智恵子, 真田弘美.
    • Organizer
      第25回日本創傷・オストミー・失禁管理学会学術集会
    • Place of Presentation
      石川県金沢市
    • Year and Date
      2016-06-11
    • Related Report
      2016 Annual Research Report
  • [Remarks] 東京大学大学院医学系研究科社会連携講座アドバンストナーシングテクノロジー ホームページ

    • URL

      http://ant.m.u-tokyo.ac.jp/

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
  • [Remarks] 東京大学大学院医学系研究科社会連携講座アドバンストナースングテクノロジー ホームページ

    • URL

      http://ant.m.u-tokyo.ac.jp/

    • Related Report
      2016 Annual Research Report

URL: 

Published: 2016-04-21   Modified: 2021-02-19  

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