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Simultaneous determination and risk screening of chlorinated polycyclic aromatic hydrocarbons and their derivatives

Research Project

Project/Area Number 16H05891
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Environmental impact assessment
Research InstitutionUniversity of Shizuoka

Principal Investigator

Miyake Yuichi  静岡県立大学, 食品栄養科学部, 助教 (40425731)

Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥20,540,000 (Direct Cost: ¥15,800,000、Indirect Cost: ¥4,740,000)
Fiscal Year 2019: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2016: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Keywordsハロゲン化多環芳香族炭化水素類 / 残留性有機汚染物質 / 廃棄物焼却 / 曝露評価 / 発生源解析 / リスク評価 / 多環芳香族炭化水素類 / ハロゲン化PAHs / 有害化学物質 / 環境分析 / PAHs / 有機ハロゲン化合物
Outline of Final Research Achievements

Halogenated polycyclic aromatic hydrocarbons are potential candidates of the persistent organic pollutants in terms of their dioxin-like toxicities and environmental persistence. Our results suggest that waste incineration could be a potential source of halogenated PAHs in Japan. We elucidated the mechanism of formation of halogenated PAHs during the combustion with a developed kinetic model describing the chlorination of PAHs. Chlorinated PAHs could be unintentionally generated during cooking of fish and meats, especially during gas-grilling (direct heating). We also found that exposure to PAHs and ClPAHs in cooking exhaust gas via inhalation could be a major route of exposure to these toxic compounds; therefore, the grilling of fish indoors may pose a health risk, especially to kitchen workers.

Academic Significance and Societal Importance of the Research Achievements

ハロゲン化PAHsやその他のPAHs誘導体のうち、従来モニタリングされていなかった物質や極めて情報が少なかった物質に関して、一般環境および発生源周辺にわたって測定事例を得られた。主要な発生源の情報が網羅的に得られ、ヒトへの主な曝露経路の推定とリスクレベルの評価できたことから、今後、ハロゲン化PAHs関連物質に関するリスクベース管理の促進への貢献が期待される。

Report

(5 results)
  • 2020 Final Research Report ( PDF )
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • Research Products

    (41 results)

All 2020 2019 2018 2017 2016

All Journal Article (14 results) (of which Int'l Joint Research: 13 results,  Peer Reviewed: 13 results,  Open Access: 2 results) Presentation (27 results) (of which Int'l Joint Research: 12 results,  Invited: 4 results)

  • [Journal Article] Quantification of Brominated Polycyclic Aromatic Hydrocarbons in Environmental Samples by Liquid Chromatography Tandem Mass Spectrometry with Atmospheric Pressure Photoionization and Post-column Infusion of Dopant2020

    • Author(s)
      Misato Masuda, Qi Wang, Masahiro Tokumura, Yuichi Miyake, Takashi Amagai
    • Journal Title

      Analytical Sciences

      Volume: 36 Issue: 9 Pages: 1105-1111

    • DOI

      10.2116/analsci.20P025

    • NAID

      130007898810

    • ISSN
      0910-6340, 1348-2246
    • Year and Date
      2020-09-10
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Risk assessment of polycyclic aromatic hydrocarbons and their chlorinated derivatives produced during cooking and released in exhaust gas2020

    • Author(s)
      Misato Masuda, Qi Wang, Masahiro Tokumura, Yuichi Miyake, Takashi Amagai
    • Journal Title

      Ecotoxicology and Environmental Safety

      Volume: 197 Pages: 110592-110592

    • DOI

      10.1016/j.ecoenv.2020.110592

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Mitigation of the inhibitory effects of co-existing substances on the Fenton process by UV light irradiation2020

    • Author(s)
      Muramatsu Kosuke、Tokumura Masahiro、Wang Qi、Miyake Yuichi、Amagai Takashi、Makino Masakazu
    • Journal Title

      Journal of Environmental Science and Health, Part A

      Volume: 55 Issue: 6 Pages: 730-738

    • DOI

      10.1080/10934529.2020.1737460

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Simultaneous determination of polycyclic aromatic hydrocarbons and their chlorinated derivatives in grilled foods2019

    • Author(s)
      Masuda Misato、Wang Qi、Tokumura Masahiro、Miyake Yuichi、Amagai Takashi
    • Journal Title

      Ecotoxicology and Environmental Safety

      Volume: 178 Pages: 188-194

    • DOI

      10.1016/j.ecoenv.2019.04.046

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Dermal exposure to plasticizers in nail polishes: An alternative major exposure pathway of phosphorus-based compounds2019

    • Author(s)
      Tokumura Masahiro、Seo Makiko、Wang Qi、Miyake Yuichi、Amagai Takashi、Makino Masakazu
    • Journal Title

      Chemosphere

      Volume: 226 Pages: 316-320

    • DOI

      10.1016/j.chemosphere.2019.03.108

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Comparison of rates of direct and indirect migration of phosphorus flame retardants from flame-retardant-treated polyester curtains to indoor dust2019

    • Author(s)
      Tokumura Masahiro、Ogo Sayaka、Kume Kazunari、Muramatsu Kosuke、Wang Qi、Miyake Yuichi、Amagai Takashi、Makino Masakazu
    • Journal Title

      Ecotoxicology and Environmental Safety

      Volume: 169 Pages: 464-469

    • DOI

      10.1016/j.ecoenv.2018.11.052

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Identification of Novel Phosphorus-Based Flame Retardants in Curtains Purchased in Japan Using Orbitrap Mass Spectrometry2018

    • Author(s)
      Miyake Yuichi、Tokumura Masahiro、Wang Qi、Amagai Takashi、Takegawa Yasuhiro、Yamagishi Yoko、Ogo Sayaka、Kume Kazunari、Kobayashi Takeshi、Takasu Shinji、Ogawa Kumiko、Kannan Kurunthachalam
    • Journal Title

      Environmental Science & Technology Letters

      Volume: 5 Issue: 7 Pages: 448-455

    • DOI

      10.1021/acs.estlett.8b00263

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Effects of characteristics of waste incinerator on emission rate of halogenated polycyclic aromatic hydrocarbon into environments2018

    • Author(s)
      Wang Qi、Miyake Yuichi、Tokumura Masahiro、Amagai Takashi、Horii Yuichi、Nojiri Kiyoshi、Ohtsuka Nobutoshi
    • Journal Title

      Science of The Total Environment

      Volume: 625 Pages: 633-639

    • DOI

      10.1016/j.scitotenv.2017.12.323

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Methods for the analysis of organophosphorus flame retardants?Comparison of GC-EI-MS, GC-NCI-MS, LC-ESI-MS/MS, and LC-APCI-MS/MS2018

    • Author(s)
      Tokumura Masahiro、Miyake Yuichi、Wang Qi、Nakayama Hayato、Amagai Takashi、Ogo Sayaka、Kume Kazunari、Kobayashi Takeshi、Takasu Shinji、Ogawa Kumiko
    • Journal Title

      Journal of Environmental Science and Health, Part A

      Volume: 53 Issue: 5 Pages: 475-481

    • DOI

      10.1080/10934529.2017.1410419

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Mechanism of Formation of Chlorinated Pyrene during Combustion of Polyvinyl Chloride2017

    • Author(s)
      Miyake Yuichi、Tokumura Masahiro、Wang Qi、Amagai Takashi、Horii Yuichi、Kannan Kurunthachalam
    • Journal Title

      Environmental Science & Technology

      Volume: 51 Issue: 24 Pages: 14100-14106

    • DOI

      10.1021/acs.est.7b04854

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Rate of hexabromocyclododecane decomposition and production of brominated polycyclic aromatic hydrocarbons during combustion in a pilot-scale incinerator2017

    • Author(s)
      Miyake Yuichi、Tokumura Masahiro、Wang Qi、Amagai Takashi、Horii Yuichi
    • Journal Title

      Journal of Environmental Sciences

      Volume: 61 Pages: 91-96

    • DOI

      10.1016/j.jes.2017.07.007

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Effects of Annual Emission Rates of Halogenated Polycyclic Aromatic Hydrocarbons from Wate Incinerators on Atmospheric Concentrations2017

    • Author(s)
      王 斉、徳村 雅弘、三宅 祐一、雨谷 敬史、堀井 勇一、蓑毛 康太郎、野尻 喜好、大塚 宜寿
    • Journal Title

      ENVIRONMENTAL SCIENCE

      Volume: 30 Issue: 6 Pages: 336-345

    • DOI

      10.11353/sesj.30.336

    • NAID

      130006230371

    • ISSN
      0915-0048, 1884-5029
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Simultaneous determination of brominated and phosphate flame retardants in flame-retarded polyester curtains by a novel extraction method2017

    • Author(s)
      Miyake Yuichi、Tokumura Masahiro、Nakayama Hayato、Wang Qi、Amagai Takashi、Ogo Sayaka、Kume Kazunari、Kobayashi Takeshi、Takasu Shinji、Ogawa Kumiko、Kannan Kurunthachalam
    • Journal Title

      Science of The Total Environment

      Volume: 601-602 Pages: 1333-1339

    • DOI

      10.1016/j.scitotenv.2017.05.249

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 廃棄物焼却により生成される新規有害化学物質の排出実態と排出削減方法2016

    • Author(s)
      三宅祐一、堀井勇一
    • Journal Title

      生活と環境

      Volume: 61 Pages: 68-72

    • Related Report
      2016 Annual Research Report
  • [Presentation] Halogenated Polycyclic Aromatic Hydrocarbons in Soil and River Sediment from E-waste Recycling Sites in Vietnam2018

    • Author(s)
      三宅祐一
    • Organizer
      日本水環境学会総会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Determination and Identification of Novel Brominated and Phosphorus Flame Retardants in Flame-Retarded Curtains2018

    • Author(s)
      Miyake Y.
    • Organizer
      2nd Chemical Hazard Symposium
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Emission and mass balance of halogenated polycyclic aromatic hydrocarbons from waste incinerator2018

    • Author(s)
      Qi Wang, Yuichi Miyake, Masahiro Tokumura, Takashi Amagai, Yuichi Horii, Kiyoshi Nojiri, Nobutoshi Ohtsuka
    • Organizer
      The 13th Japan-China International Symposium on Health Sciences
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] An Analytical Method for Chlorinated Polycyclic Aromatic Hydrocarbons in Particles by Thermal Desorption-GC/MS2018

    • Author(s)
      Kento Sei, Qi Wang, Misato Masuda, Masahiro Tokumura, Yuichi Miyake, Takashi Amagai
    • Organizer
      the 38th International Symposium on Halogenated Persistent Organic Pollutants (POPs) & 10th International PCB Workshop (Dioxin 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Unintentional Generation of Chlorinated Polycyclic Aromatic Hydrocarbons during Cooking2018

    • Author(s)
      Misato Masuda, Qi Wang, Masahiro Tokumura, Yuichi Miyake, Takashi Amagai
    • Organizer
      The 38th International Symposium on Halogenated Persistent Organic Pollutants (POPs) & 10th International PCB Workshop (Dioxin 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Environmental impact of halogenated polycyclic aromatic hydrocarbons emitted from E-waste recycling activities in Vietnam2018

    • Author(s)
      Qi Wang, Masahiro Tokumura, Yuichi Miyake, Takashi Amagai
    • Organizer
      The 12th Asia Impact Assessment Conference (AIC 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Determination of Chlorinated Polycyclic Aromatic Hydrocarbons in Sediments2018

    • Author(s)
      Misato Masuda, Qi Wang, Masahiro Tokumura, Yuichi Miyake, Takashi Amagai
    • Organizer
      The Water and Environment Technology Conference 2018 (WET 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 調理により生成する多環芳香族炭化水素とその塩素化体の経路別曝露量の比較2018

    • Author(s)
      増田 美里, 王 斉, 徳村 雅弘, 三宅 祐一, 雨谷 敬史
    • Organizer
      環境科学会 2018年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 塩素化多環芳香族炭化水素類 (ClPAHs) 個人曝露評価のための高感度分析法の開発2018

    • Author(s)
      清 健人, 王 斉, 増田 美里, 徳村 雅弘, 三宅 祐一, 雨谷 敬史
    • Organizer
      環境科学会 2018年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 加熱脱着-GC/MSを用いた粒子状塩素化多環芳香族炭化水素類(ClPAHs)分析法の開発2018

    • Author(s)
      清 健人, 王 斉, 徳村 雅弘, 三宅 祐一, 雨谷 敬史
    • Organizer
      第27回環境化学討論会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 底質および魚介類中の塩素化ピレンとそのヒドロキシ誘導体の分析法の開発2018

    • Author(s)
      増田 美里, 王 斉, 徳村 雅弘, 三宅 祐一, 雨谷 敬史
    • Organizer
      第27回環境化学討論会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Generation of polycyclic aromatic hydrocarbons and their derivatives during cooking2018

    • Author(s)
      Misato Masuda, Qi Wang, Masahiro Tokumura, Yuichi Miyake, Takashi Amagai
    • Organizer
      The 4th International Conference on Pharma and Food (ICPF2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Risk assessment of polycyclic aromatic hydrocarbons and their chlorinated derivativesproduced by cooking2018

    • Author(s)
      Misato Masuda, Qi Wang, Masahiro Tokumura, Yuichi Miyake, Takashi Amagai
    • Organizer
      The 23rd Shizuoka Forum on Health and Longevity
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 加熱調理により生成した多環芳香族炭化水素とその塩素化体の曝露経路別リスク評価2018

    • Author(s)
      増田 美里, 王 斉, 徳村 雅弘, 三宅 祐一, 雨谷 敬史
    • Organizer
      平成30年室内環境学会学術大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 加熱脱着法を用いた塩素化多環芳香族炭化水素類 (ClPAHs) の室内濃度の実態調査2018

    • Author(s)
      清 健人, 王 斉, 増田 美里, 徳村 雅弘, 三宅 祐一, 雨谷 敬史
    • Organizer
      平成30年室内環境学会学術大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 新規環境汚染物質である塩素化多環芳香族炭化水素類の包括的かつ統合的環境影響評価2018

    • Author(s)
      天野 あすか, 五老 祐大, 徳村 雅弘, 王 斉, 内藤 博敬, 三宅 祐一, 雨谷 敬史, 牧野 正和
    • Organizer
      環境科学会 2018年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 塩素化多環芳香族炭化水素類(ClPAHs)とその誘導体の生体毒性評価2018

    • Author(s)
      相内 博, 徳村 雅弘, 五老 祐大, 王 斉, 三宅 祐一, 雨谷 敬史, 牧野 正和
    • Organizer
      第52回日本水環境学会年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 水生生物中のハロゲン化多環芳香族炭化水素及びその誘導体の分析法の開発2018

    • Author(s)
      増田 美里, 相内 博, 徳村 雅弘, 五老 祐大, 王 斉, 三宅 祐一, 雨谷 敬史, 牧野 正和
    • Organizer
      第52回日本水環境学会年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] An Analytical Method for Polycyclic Aromatic Hydrocarbons and their Derivatives in Fish Oil Derived from Grilled Fish2017

    • Author(s)
      Masuda M., Wang Q., Tokumura M., Miyake Y., Amagai T.
    • Organizer
      37th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 実験炉を用いたヘキサブロモシクロドデカンの燃焼に伴う非意図的な臭素化多環芳香族炭化水素類の生成2017

    • Author(s)
      王 斉,三宅 祐一,徳村 雅弘,雨谷 敬史,堀井 勇一
    • Organizer
      第26回環境化学討論会
    • Related Report
      2017 Annual Research Report
  • [Presentation] くん煙材の発煙温度と発煙量および多環芳香族炭化水素(PAHs)の生成量2017

    • Author(s)
      鈴木 進二,倉石 祐,三宅 祐一,雨谷 敬史
    • Organizer
      第26回環境化学討論会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 魚油を含む食品中の多環芳香族炭化水素とその誘導体の分析法の検討2017

    • Author(s)
      増田 美里,王 斉,徳村 雅弘,三宅 祐一,雨谷 敬史
    • Organizer
      第26回環境化学討論会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 食品中の多環芳香族炭化水素およびその誘導体の分析2017

    • Author(s)
      増田美里,王 斉,徳村 雅弘,三宅 祐一,雨谷 敬史
    • Organizer
      環境科学会2017年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 調理中に発生する多環芳香族炭化水素およびその誘導体の検討2017

    • Author(s)
      増田 美里,王 斉,徳村 雅弘,三宅 祐一,雨谷 敬史
    • Organizer
      平成29年室内環境学会学術大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Halogenated Polycyclic Aromatic Hydrocarbons in Soil and River Sediment from E-waste Recycling Sites in Vietnam2016

    • Author(s)
      Miyake Y.
    • Organizer
      Special Seminar on Environmental Sciencese in University of Dhaka
    • Place of Presentation
      Dhaka, Bangladesh
    • Year and Date
      2016-12-23
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Concentrations of Halogenated Polycyclic Aromatic Hydrocarbons in Atmosphere in Japan2016

    • Author(s)
      Wang Q., Miyake Y., Tokumura M., Amagai T., Horii Y., Minomo K., Ohtsuka N.
    • Organizer
      The 9th International PCB Workshop
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2016-10-10
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Concentration profiles of halogenated polycyclic aromatic hydrocarbons in soil and river sediment from recycling sites in Vietnam2016

    • Author(s)
      Miyake Y., Wang Q., Amagai T., Suzuki G., Matsukami H., Tue N.M., Takahashi S., Tanabe S., Tuyen L.H., Viet P.H., Takigami H.
    • Organizer
      36th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin2016)
    • Place of Presentation
      Firenze, Italy
    • Year and Date
      2016-08-28
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research

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Published: 2016-04-21   Modified: 2022-01-27  

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