• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of super-resolution dark-spot imaging by manipulation of all parameters of light

Research Project

Project/Area Number 16H05985
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Optical engineering, Photon science
Research InstitutionTohoku University

Principal Investigator

Kozawa Yuichi  東北大学, 多元物質科学研究所, 准教授 (90509126)

Research Collaborator Sato Shunichi  
Nemoto Tomomi  
Ishi Hirokazu  
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2018: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2017: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2016: ¥11,440,000 (Direct Cost: ¥8,800,000、Indirect Cost: ¥2,640,000)
Keywordsレーザー顕微鏡 / 超解像 / ベクトルビーム
Outline of Final Research Achievements

This research project aimed to develop a new method to enhance the spatial resolution in confocal laser scanning microscopy by exploiting vector beams, which have axially symmetric polarization distribution. In this method, the enhancement of the spatial resolution is achieved by the simple subtraction process for images separately acquired by different vector beams with various focal spot shapes. The focal spot shape is controlled by manipulating the spatial distributions of polarization and phase for vector beams. Based on this principle, the spatial resolution close to 100 nm was experimentally demonstrated in visible light imaging.

Academic Significance and Societal Importance of the Research Achievements

レーザー顕微鏡法は,多様な学術分野あるいは産業現場において広く普及している必須の観察手法である.一方で,光を用いた顕微鏡法であるため,観察対象として解像可能な最小サイズは使用する光の波長程度であり,可視光を用いた場合の空間分解能の限界は200 nm前後とされている.本研究成果は,このような従来のレーザー顕微鏡法に対して,使用するレーザー光をベクトルビームとするだけで従来の限界を超えた高い空間分解能が容易に得られること実証した点に大きな意義があり,広く様々な分野での活用につながることが期待される.

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • Research Products

    (37 results)

All 2019 2018 2017 2016 Other

All Journal Article (5 results) (of which Peer Reviewed: 4 results,  Open Access: 1 results) Presentation (29 results) (of which Int'l Joint Research: 8 results,  Invited: 10 results) Book (1 results) Remarks (2 results)

  • [Journal Article] Subtraction imaging by the combination of higher order vector beams for enhanced spatial resolution2019

    • Author(s)
      Yuichi Kozawa and Shunichi Sato
    • Journal Title

      Optics Letters

      Volume: 44 Issue: 4 Pages: 883-886

    • DOI

      10.1364/ol.44.000883

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Vector beam generation from vertical cavity surface emitting lasers2018

    • Author(s)
      Yuichi Kozawa, Yuki Nara, Naoto Jikutani, Yasuhiro Higashi, and Shunichi Sato
    • Journal Title

      Optics Letters

      Volume: 43 Issue: 22 Pages: 5659-5662

    • DOI

      10.1364/ol.43.005659

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Superresolution imaging via superoscillation focusing of a radially polarized beam2018

    • Author(s)
      Yuichi Kozawa, Daichi Matsunaga, Shunichi Sato
    • Journal Title

      Optica

      Volume: 5 Issue: 2 Pages: 749-759

    • DOI

      10.1364/optica.5.000086

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Micro-hole drilling by tightly focused vector beams2018

    • Author(s)
      Shugo Matsusaka, Yuichi Kozawa, Shunichi Sato
    • Journal Title

      Optics Letters

      Volume: 43 Issue: 7 Pages: 1542-1545

    • DOI

      10.1364/ol.43.001542

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 高次径偏光ビームの軸方向電場を用いた共焦点イメージング2017

    • Author(s)
      小澤祐市, 阪下良太, 佐藤俊一
    • Journal Title

      光アライアンス

      Volume: 28 Pages: 16-20

    • Related Report
      2017 Annual Research Report
  • [Presentation] 光波の強度・偏光・位相の空間分布制御と光マニピュレーション応用2019

    • Author(s)
      小澤 祐市, 佐藤 俊一
    • Organizer
      第66回応用物理学会春季学術講演会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 高次ベクトルビームを用いた差引イメージングの生体試料への適用2019

    • Author(s)
      吉田 実生, 小澤 祐市, 佐藤 俊一
    • Organizer
      第66回応用物理学会春季学術講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] レーザー光の偏光・位相の空間分布制御に基づく光イメージングの高度化2018

    • Author(s)
      小澤 祐市, 佐藤 俊一
    • Organizer
      第3期第2回レーザー学会「レーザーバイオ医療」技術専門委員会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 光波の強度・位相・偏光の空間分布制御と光イメージング応用2018

    • Author(s)
      小澤 祐市, 佐藤 俊一
    • Organizer
      第19 回情報フォトニクス研究会( 秋合宿 )
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 光フィードバック光学系を用いた面発光レーザーからの高次ベクトルビームの発生2018

    • Author(s)
      奈良 優樹, 小澤 祐市, 佐藤 俊一, 軸谷 直人, 東 康弘
    • Organizer
      第 79 回応用物理学会秋季学術講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] ベクトルビームを用いた差引イメージングにおける集光ビームの最適化と高分 解能化2018

    • Author(s)
      吉田 実生, 小澤 祐市, 佐藤 俊一
    • Organizer
      第 79 回応用物理学会秋季学術講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 高次ベクトルビームを用いた差引イメージングによる共焦点レーザー顕微鏡の空間分解能向上2018

    • Author(s)
      吉田 実生, 小澤 祐市, 佐藤 俊一
    • Organizer
      応用物理学会東北支部第 73 回学術講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Spatial resolution enhancement in laser scanning microscopy using vector beams2018

    • Author(s)
      Yuichi Kozawa, Shunichi Sato
    • Organizer
      The 4th Biomedical Imaging and Sensing Conference 2018 (BISC2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Acceleration of Micro-Hole Drilling by an Azimuthally Polarized Laser Beam under Tight Focusing Condition2018

    • Author(s)
      Shugo Matsusaka, Yuichi Kozawa, Shunichi Sato
    • Organizer
      Conference on Lasers and Electro-Optics (CLEO) 2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Generation of Cylindrical Vector Beams from Vertical- Cavity Surface-Emitting Laser with Optical Feedback2018

    • Author(s)
      Yuki Nara, Yuichi Kozawa, Shunichi Sato
    • Organizer
      Conference on Lasers and Electro-Optics (CLEO) 2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 複屈折レンズを用いた光フィードバック光学系による面発光レーザーからのベクトルビームの発生2018

    • Author(s)
      奈良 優樹, 小澤 祐市, 佐藤 俊一
    • Organizer
      第65回応用物理学会春季学術講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ベクトルビームを用いた微細穴あけ加工における偏光の効果2018

    • Author(s)
      松坂 修吾, 小澤 祐市, 佐藤 俊一
    • Organizer
      第65回応用物理学会春季学術講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 位相補償を用いた光ファイバー増幅器における高出力・高品質ベクトルビーム発生2017

    • Author(s)
      小澤 祐市, 佐藤 俊一
    • Organizer
      第64回応用物理学会春季学術講演会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2017-03-14
    • Related Report
      2016 Annual Research Report
  • [Presentation] 軸方向電場を用いた共焦点イメージングにおけるサイドローブの抑制2017

    • Author(s)
      阪下 良太, 小澤 祐市, 佐藤 俊一
    • Organizer
      第64回応用物理学会春季学術講演会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2017-03-14
    • Related Report
      2016 Annual Research Report
  • [Presentation] ベクトルビームにおける振幅・偏光・位相の空間分布制御と光イメージング応用2017

    • Author(s)
      小澤 祐市, 佐藤 俊一
    • Organizer
      Optics & Photonics Japan 2017
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Enhanced Spatial Resolution by Subtraction Imaging Using Higher-Order Vector Beams2017

    • Author(s)
      Yuichi Kozawa, Daichi Matsunaga, Shunichi Sato
    • Organizer
      Focus on Microscopy (FOM2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Long Depth-of-Focus Imaging by a Non-Diffracting Optical Needle under Strong Aberration2017

    • Author(s)
      Yuichi Kozawa, Shunichi Sato
    • Organizer
      Conference on Lasers and Electro-Optics (CLEO)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Enhanced Spatial Resolution in Laser Microscopy by the Longitudinal Field of a Radially Polarized Beam2017

    • Author(s)
      Y. Kozawa, R. Sakashita, S. Sato
    • Organizer
      The 24th Congress of the International Commission for Optics (ICO-24)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Subtraction Imaging by Higher-Order Vector Beams for Spatial Resolution Enhancement2017

    • Author(s)
      Yuichi Kozawa, Daichi Matsunaga, Shunichi Sato
    • Organizer
      6th Tohoku University Optical Science and Engineering Forum
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 光波の偏光・位相・強度分布制御に基づく新しいレーザー光の発生と応用2017

    • Author(s)
      小澤祐市, 佐藤俊一
    • Organizer
      高分子・ハイブリッド材料研究センター(PHyM)講演会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 面発光半導体レーザーからの径偏光ビーム発生の検討2017

    • Author(s)
      奈良 優樹, 小澤 祐市, 佐藤 俊一
    • Organizer
      第78回応用物理学会秋季学術講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 強く集光したベクトルビームによるレーザー微細穴あけ加工2017

    • Author(s)
      松坂 修吾, 小澤 祐市, 佐藤 俊一
    • Organizer
      第78回応用物理学会秋季学術講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ベクトルビームの基礎とイメージング応用2017

    • Author(s)
      小澤祐市, 佐藤俊一
    • Organizer
      第143回微小光学研究会
    • Place of Presentation
      上智大学 (東京都千代田区)
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 高次径偏光ビームを用いた共焦点イメージングにおける偏光特性の検討2016

    • Author(s)
      阪下 良太, 小澤 祐市, 佐藤 俊一
    • Organizer
      応用物理学会東北支部第71回学術講演会
    • Place of Presentation
      東北大学(仙台市)
    • Year and Date
      2016-12-01
    • Related Report
      2016 Annual Research Report
  • [Presentation] Resolution enhancement in confocal microscopy with vector beams2016

    • Author(s)
      Shunichi Sato, Yuichi Kozawa
    • Organizer
      第54回日本生物物理学会年会
    • Place of Presentation
      つくば国際会議場(つくば市)
    • Year and Date
      2016-11-25
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] レーザー光の強度・偏光・位相の空間分布制御と応用2016

    • Author(s)
      小澤 祐市
    • Organizer
      日本顕微鏡学会 様々なイメージング技術研究部会 第4回研究会
    • Place of Presentation
      ホテル紫雲閣(東松山市)
    • Year and Date
      2016-11-20
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 高次径偏光ビームの軸方向電場を用いた共焦点イメージング2016

    • Author(s)
      阪下 良太, 小澤 祐市, 佐藤 俊一
    • Organizer
      第77回応用物理学会秋季学術講演会
    • Place of Presentation
      朱鷺メッセ(新潟市)
    • Year and Date
      2016-09-13
    • Related Report
      2016 Annual Research Report
  • [Presentation] Super-Oscillation by Higher-Order Radially Polarized Laguerre-Gaussian Beams2016

    • Author(s)
      Daichi Matsunaga, Yuichi Kozawa, Shunichi Sato
    • Organizer
      Conference on Lasers and Electro-Optics (CLEO) 2016
    • Place of Presentation
      San Jose (USA)
    • Year and Date
      2016-06-05
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ベクトルビームレーザー光の光イメージング応用2016

    • Author(s)
      小澤 祐市
    • Organizer
      第1回フロンティアバイオイメージング研究会
    • Place of Presentation
      東北大学(仙台市)
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Book] Super-Resolution Two-Photon Excitation Microscopy Utilizing Transmissive Liquid Crystal Devices (Super-Resolution Imaging in Biomedicine,Chapter 10)2016

    • Author(s)
      Kohei Otomo, Terumasa Hibi, Yuichi Kozawa, Sari Ipponjima, Shunichi Sato, Tomomi Nemoto
    • Total Pages
      426
    • Publisher
      CRC Press
    • Related Report
      2016 Annual Research Report
  • [Remarks] 東北大学多元物質科学研究所 佐藤俊一研究室

    • URL

      http://satolab.tagen.tohoku.ac.jp/

    • Related Report
      2018 Annual Research Report 2016 Annual Research Report
  • [Remarks] 東北大学多元物質科学研究所 佐藤俊一研究室

    • URL

      http://satolab.tagen.tohoku.ac.jp/

    • Related Report
      2017 Annual Research Report

URL: 

Published: 2016-04-21   Modified: 2020-03-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi