| Budget Amount *help |
¥25,480,000 (Direct Cost: ¥19,600,000、Indirect Cost: ¥5,880,000)
Fiscal Year 2019: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2018: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2017: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
Fiscal Year 2016: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
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| Outline of Final Research Achievements |
Trifluoromethyl (CF3), difluoromethyl (CF2H), and monofluoromethyl (CH2F) groups are versatile structural motifs, especially in the fields of pharmaceuticals, agrochemicals, and organic functional materials. Thus, development of new protocols for fluoromethylation of various skeletons has become a vital subject to be studied in the field of organic synthetic chemistry. For the past several years, photoredox catalysis has emerged as a useful tool for radical reactions through visible-light-induced single-electron-transfer (SET) processes. Here we have developed photocatalytic radical fluoromethylation for simple synthesis of valuable organofluorine compounds.
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